Pseudomonas aeruginosa is one of the most common pathogenic bacteria, frequently found in different environmental samples. The prevalence of multidrug resistant isolates has become an alarming concern for both patient...Pseudomonas aeruginosa is one of the most common pathogenic bacteria, frequently found in different environmental samples. The prevalence of multidrug resistant isolates has become an alarming concern for both patients and their surroundings. The present study was carried out to record prevalence of P. aeruginosa in surface water of Dhaka city and to screen their antibiotic resistance pattern. The study was also extended to typing of resistant isolates according to extended spectrum beta lactamase production. Hereby, Kirby-Bauer method was applied to test antibiotic sensitivity according to Clinical and Laboratory Standards Institute. Then, the Ampicillin resistant isolates were screened for ESBL production by Double Disk Synergy Test (DDST). In these prospects, 52 water samples were tested, of which 32 were found positive for P. aeruginosa isolates. Hundred percent of the positive isolates were found to Ampicillin (AMP) resistant followed by 93.7% to both Tetracycline and Gentamycin and 71.8% to Co-triimoxazole. P. aeruginosa is completely susceptible to third generation antibiotics ciprofloxacin, Imipenem and Aztreonam followed by moderately susceptible to Polymyxin-B (78.2%) and Colistin (87.5%). According to DDST, all of the susceptible isolates were found positive for AMC type beta-lactamase production. It is evident from this study that the surface water is contaminated with antibiotic resistant P. aeruginosa and that through the water systems antibiotic resistance can be transferred to humans and animals. So, appropriate and rationale use of antibiotic should be applied to minimize the emergence of multidrug isolates to environment.展开更多
The present work gives a methodology for assessing radiological concentration of 131I, 132I, 133I, 134I, and 135I due to a hypothetical accident of TRIGA Mark-II research Reactor at AERE, Savar, Bangladesh. The concen...The present work gives a methodology for assessing radiological concentration of 131I, 132I, 133I, 134I, and 135I due to a hypothetical accident of TRIGA Mark-II research Reactor at AERE, Savar, Bangladesh. The concentrations were estimated through different pathways like ingestion of vegetation, milk, and meat from air and ground deposition. The maximum air concentrations for all 16 directions were found at 110 m distance from the core of the reactor and it was found to be highest in the southern (S) direction. The maximum ground concentration occurred immediately just after the accident in different directions. In all pathways, the most concentration was found to be in S-direction. The concentrations in vegetation of 131I, 133I, 135I were significant, while no concentrations of 132I and 134I were observed. The concentration in vegetation for 131I was found to be highest than all other isotopes of iodine. The concentrations of 133I were found to be higher and concentrations of 134I were observed to be lower in both milk and meat compared to other radio isotopes of iodine. In the case of a radiological accident, the results of the present study will be a valuable guide for adopting radiological safety measures for radiation protection against the ingestion of vegetables, milk and meat from around the research reactor at AERE, Savar, Bangladesh.展开更多
文摘Pseudomonas aeruginosa is one of the most common pathogenic bacteria, frequently found in different environmental samples. The prevalence of multidrug resistant isolates has become an alarming concern for both patients and their surroundings. The present study was carried out to record prevalence of P. aeruginosa in surface water of Dhaka city and to screen their antibiotic resistance pattern. The study was also extended to typing of resistant isolates according to extended spectrum beta lactamase production. Hereby, Kirby-Bauer method was applied to test antibiotic sensitivity according to Clinical and Laboratory Standards Institute. Then, the Ampicillin resistant isolates were screened for ESBL production by Double Disk Synergy Test (DDST). In these prospects, 52 water samples were tested, of which 32 were found positive for P. aeruginosa isolates. Hundred percent of the positive isolates were found to Ampicillin (AMP) resistant followed by 93.7% to both Tetracycline and Gentamycin and 71.8% to Co-triimoxazole. P. aeruginosa is completely susceptible to third generation antibiotics ciprofloxacin, Imipenem and Aztreonam followed by moderately susceptible to Polymyxin-B (78.2%) and Colistin (87.5%). According to DDST, all of the susceptible isolates were found positive for AMC type beta-lactamase production. It is evident from this study that the surface water is contaminated with antibiotic resistant P. aeruginosa and that through the water systems antibiotic resistance can be transferred to humans and animals. So, appropriate and rationale use of antibiotic should be applied to minimize the emergence of multidrug isolates to environment.
文摘The present work gives a methodology for assessing radiological concentration of 131I, 132I, 133I, 134I, and 135I due to a hypothetical accident of TRIGA Mark-II research Reactor at AERE, Savar, Bangladesh. The concentrations were estimated through different pathways like ingestion of vegetation, milk, and meat from air and ground deposition. The maximum air concentrations for all 16 directions were found at 110 m distance from the core of the reactor and it was found to be highest in the southern (S) direction. The maximum ground concentration occurred immediately just after the accident in different directions. In all pathways, the most concentration was found to be in S-direction. The concentrations in vegetation of 131I, 133I, 135I were significant, while no concentrations of 132I and 134I were observed. The concentration in vegetation for 131I was found to be highest than all other isotopes of iodine. The concentrations of 133I were found to be higher and concentrations of 134I were observed to be lower in both milk and meat compared to other radio isotopes of iodine. In the case of a radiological accident, the results of the present study will be a valuable guide for adopting radiological safety measures for radiation protection against the ingestion of vegetables, milk and meat from around the research reactor at AERE, Savar, Bangladesh.
