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RG7388 inhibits SFTSV replication by suppressing MDM2-mediated p53 degradation and preventing apoptosome disruption
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作者 Zixiang Liu Mengqian Huang +9 位作者 Yuyang Liu luna cui Xixi Shi Honghua Chen Xiaoning Gao Zining Wang Qinting Lin Zhiyun Wang Yue Teng Tao Wang 《Science Bulletin》 2026年第1期55-59,共5页
Severe fever with thrombocytopenia syndrome virus(SFTSV)is an emerging bunyavirus that causes severe fever with thrombocytopenia syndrome(SFTS)[1]and is showing a trend toward global transmission[2].Therefore,a compre... Severe fever with thrombocytopenia syndrome virus(SFTSV)is an emerging bunyavirus that causes severe fever with thrombocytopenia syndrome(SFTS)[1]and is showing a trend toward global transmission[2].Therefore,a comprehensive understanding of the pathogenic mechanism of SFTSV remains crucial. 展开更多
关键词 severe fever thrombocytopenia syndrome apoptosome severe fever thrombocytopenia syndrome sfts degradation SFTSV MDM rg replication
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