Photobiomodulation(PBM)-the irradiation of cells or tissues with low-intensity red to near-infrared light-is emerging as an effective means of enhancing cell and tissue resilience and repair.As reviewed elsewhere(Gord...Photobiomodulation(PBM)-the irradiation of cells or tissues with low-intensity red to near-infrared light-is emerging as an effective means of enhancing cell and tissue resilience and repair.As reviewed elsewhere(Gordon et al.,2019),the intracellular effects of PBM appear to be primarily mediated by cytochrome C oxidase,a key enzyme in the mitochondrial respiratory chain and a primary photoacceptor of red to near-infrared light.Absorption of light by cytochrome C oxidase alters its redox state,resulting in increased ATP production,the liberation of nitric oxide and a transient burst in reactive oxygen species.展开更多
文摘Photobiomodulation(PBM)-the irradiation of cells or tissues with low-intensity red to near-infrared light-is emerging as an effective means of enhancing cell and tissue resilience and repair.As reviewed elsewhere(Gordon et al.,2019),the intracellular effects of PBM appear to be primarily mediated by cytochrome C oxidase,a key enzyme in the mitochondrial respiratory chain and a primary photoacceptor of red to near-infrared light.Absorption of light by cytochrome C oxidase alters its redox state,resulting in increased ATP production,the liberation of nitric oxide and a transient burst in reactive oxygen species.