Purpose: Gastrointestinal stromal tumor (GIST) has been considered radiation-resistant and data on the radiotherapy for GIST in previous studies are lacking. The purpose of this article is to accumulate more experienc...Purpose: Gastrointestinal stromal tumor (GIST) has been considered radiation-resistant and data on the radiotherapy for GIST in previous studies are lacking. The purpose of this article is to accumulate more experience in the application of radiotherapy for GISTs. Materials and methods: Review our own case material and the relevant English literature. Results: A huge pelvic GIST after resistance to tyrosine kinase inhibitors (TKIs) has been well controlled by simultaneous-integrated boost intensity-modulated radiation therapy (SIB-IMRT). The time from the initial shrinkage of the mass and subsequent stabilization to now was more than 18 months. The patient was palliated from the series of symptoms caused by tumor compression and well tolerated to the adverse reactions by radiotherapy. And the previous studies have shown that GISTs had a certain sensitivity to radiotherapy. Conclusion: SIB-IMRT may provide a new means of achieving objective response and prolonging survival in selected GIST patients.展开更多
This study aims to improve the value of fast-growing wood and extend the heat-treated wood utilization using inorganic calcium carbonate(CaCO_(3))crystals via an in-situ synthesis method.CaCl_(2)and Na 2CO_(3)solution...This study aims to improve the value of fast-growing wood and extend the heat-treated wood utilization using inorganic calcium carbonate(CaCO_(3))crystals via an in-situ synthesis method.CaCl_(2)and Na 2CO_(3)solutions with a concentration ratio of 1:1 were successively introduced into the thermally modified poplar wood obtained by steam heat treatment(HT)at 200℃for 1.5 and 3 h,resulting in the in-situ synthesis of CaCO_(3)crystals inside the heat-treated wood.The filling effect was best at the concentration of 1.2 mol/L.CaCO_(3)was uniformly distributed in the cell cavities of the heat-treated wood,and some of the crystals were embedded in the fissures of the wood cell walls.The morphology of CaCO_(3)crystals was mainly spherical and rhombic polyhedral.Three main types of CaCO_(3)crystals were calcite,vaterite,and aragonite.The HT of poplar wood at 200℃resulted in degrading the chemical components of the wood cell wall.This degradation led to reduced wood mechanical properties,including the surface hardness(HD),modulus of rupture(MOR),and modulus of elasticity(MOE).After CaCO_(3)was in-situ synthesized in the heat-treated wood,the HD increased by 18.36%and 16.35%,and MOR increased by 14.64%and 8.89%,respectively.Because of the CaCO_(3)synthesization,the char residue of the 200℃heat-treated wood samples increased by 9.31%and the maximum weight loss rate decreased by 19.80%,indicating that the filling with CaCO_(3)cannot only improve the mechanical properties of the heat-treated wood but also effectively enhance its thermal stability.展开更多
文摘Purpose: Gastrointestinal stromal tumor (GIST) has been considered radiation-resistant and data on the radiotherapy for GIST in previous studies are lacking. The purpose of this article is to accumulate more experience in the application of radiotherapy for GISTs. Materials and methods: Review our own case material and the relevant English literature. Results: A huge pelvic GIST after resistance to tyrosine kinase inhibitors (TKIs) has been well controlled by simultaneous-integrated boost intensity-modulated radiation therapy (SIB-IMRT). The time from the initial shrinkage of the mass and subsequent stabilization to now was more than 18 months. The patient was palliated from the series of symptoms caused by tumor compression and well tolerated to the adverse reactions by radiotherapy. And the previous studies have shown that GISTs had a certain sensitivity to radiotherapy. Conclusion: SIB-IMRT may provide a new means of achieving objective response and prolonging survival in selected GIST patients.
基金funded by“Natural Science Foundation of Anhui Province,Grant No.2008085QC130”.
文摘This study aims to improve the value of fast-growing wood and extend the heat-treated wood utilization using inorganic calcium carbonate(CaCO_(3))crystals via an in-situ synthesis method.CaCl_(2)and Na 2CO_(3)solutions with a concentration ratio of 1:1 were successively introduced into the thermally modified poplar wood obtained by steam heat treatment(HT)at 200℃for 1.5 and 3 h,resulting in the in-situ synthesis of CaCO_(3)crystals inside the heat-treated wood.The filling effect was best at the concentration of 1.2 mol/L.CaCO_(3)was uniformly distributed in the cell cavities of the heat-treated wood,and some of the crystals were embedded in the fissures of the wood cell walls.The morphology of CaCO_(3)crystals was mainly spherical and rhombic polyhedral.Three main types of CaCO_(3)crystals were calcite,vaterite,and aragonite.The HT of poplar wood at 200℃resulted in degrading the chemical components of the wood cell wall.This degradation led to reduced wood mechanical properties,including the surface hardness(HD),modulus of rupture(MOR),and modulus of elasticity(MOE).After CaCO_(3)was in-situ synthesized in the heat-treated wood,the HD increased by 18.36%and 16.35%,and MOR increased by 14.64%and 8.89%,respectively.Because of the CaCO_(3)synthesization,the char residue of the 200℃heat-treated wood samples increased by 9.31%and the maximum weight loss rate decreased by 19.80%,indicating that the filling with CaCO_(3)cannot only improve the mechanical properties of the heat-treated wood but also effectively enhance its thermal stability.