BACKGROUND Differentiated thyroid cancer(DTC)often seriously impacts patients’lives.Radionuclide Iodine-131(131I)is widely used in treating patients with DTC.However,most patients know little about radionuclide thera...BACKGROUND Differentiated thyroid cancer(DTC)often seriously impacts patients’lives.Radionuclide Iodine-131(131I)is widely used in treating patients with DTC.However,most patients know little about radionuclide therapy,and the treatment needs to be performed in a special isolation ward,which can cause anxiety and depression.AIM To explore anxiety and depression status and their influencing factors after 131I treatment in patients with DTC.METHODS A questionnaire survey was conducted among postoperative patients with DTC who received 131I treatment at our hospital from June 2020 to December 2022.General patient data were collected using a self-administered demographic characteristics questionnaire.The self-rating depression scale and self-rating anxiety scale were used to determine whether patients were worried about their symptoms and the degree of anxiety and depression.The patients were categorized into anxiety,non-anxiety,depression,and non-depression groups.Singlevariable and multiple-variable analyses were used to determine the risk factors for anxiety and depression in patients with thyroid cancer after surgery.RESULTS A total of 144 patients were included in this study.The baseline mean score of self-rating anxiety and depression scales were 50.06±16.10 and 50.96±16.55,respectively.Notably,48.62%(70/144)had anxiety and 47.22%(68/144)of the patients had depression.Sex,age,education level,marital status,household income,underlying diseases,and medication compliance significantly differed among groups(P<0.05).Furthermore,multivariate logistic regression analysis showed that education level,per capita monthly household income,and medication compliance level affected anxiety(P=0.015,0.001,and 0.001 respectively).Patient’s sex,marital status,and underlying diseases affected depression(P=0.007,0.001,and 0.009,respectively).CONCLUSION Nursing interventions aiming at reducing the risk of anxiety and depression should target unmarried female patients with low education level,low family income,underlying diseases,and poor adherence to medications.展开更多
All-season thermal management with zero energy consumption and emissions is more crucial to global decarbonization over traditional energy-intensive cooling/heating systems.However,the static single thermal management...All-season thermal management with zero energy consumption and emissions is more crucial to global decarbonization over traditional energy-intensive cooling/heating systems.However,the static single thermal management for cooling or heating fails to self-regulate the temperature in dynamic seasonal temperature condition.Herein,inspired by the dual-temperature regulation function of the fur color changes on the backs and abdomens of penguins,a smart thermal management composite hydrogel(PNA@H-PM Gel)system was subtly created though an"on-demand"dual-layer structure design strategy.The PNA@H-PM Gel system features synchronous solar and thermal radiation modulation as well as tunable phase transition temperatures to meet the variable seasonal thermal requirements and energy-saving demands via self-adaptive radiative cooling and solar heating regulation.Furthermore,this system demonstrates superb modulations of both the solar reflectance(ΔR=0.74)and thermal emissivity(ΔE=0.52)in response to ambient temperature changes,highlighting efficient temperature regulation with average radiative cooling and solar heating effects of 9.6℃in summer and 6.1℃in winter,respectively.Moreover,compared to standard building baselines,the PNA@H-PM Gel presents a more substantial energy-saving cooling/heating potentials for energy-efficient buildings across various regions and climates.This novel solution,inspired by penguins in the real world,will offer a fresh approach for producing intelligent,energy-saving thermal management materials,and serve for temperature regulation under dynamic climate conditions and even throughout all seasons.展开更多
Global warming and energy crisis are two major challenges in the new-century.Wearable materials that enable all-seasonal self-adapting thermal comfort without additional energy-input attract significant attention as a...Global warming and energy crisis are two major challenges in the new-century.Wearable materials that enable all-seasonal self-adapting thermal comfort without additional energy-input attract significant attention as a solution to the increasing severity of extreme climate-change.Inspired by autologous temperature-regulation and multidimensional-sensing origins of nature-skin composed of nature collagen fibers,this study engineered a nanoscale wearable natural fibers-derived thermochromic material(TMEH-skin)for robust all-season self-adapting thermal management by tactically integrating traditional immersion and spraying methods with layer-by-layer stacking-strategy.Because of the on-demand multi-functional layer-structure design,TMEH-skin achieves spontaneous~38.16%visible lightmodulation and~95.1%infrared-emission,demonstrating outstanding double-self-switching thermal management origins by simple color-changing without additional energy-input.Moreover,TMEH-skin has gratifying tensile strength of 13.18 MPa,water vapor permeability,electrical-conductivity,and hydrophobicity,further broadening the application potential and scenarios as wearable materials.In applications for military-missions or reconnaissance behind enemy-lines,TMEH-skin robustly integrates the multi-functionalities of wearing-comfort,physiological signal-response capability for accurate transmission of Morse-code,and thermal management performances under special circumstances,indicating its tremendous potential for smart military-applications.Simulation results show that TMEH-skin has prominent energy-saving efficiency in cities with different climate zones.This study provides a new reference to the booming innovation of natural-derived wearable materials for all-seasonal self-adapting thermal management.展开更多
Rapid population growth in recent decades has intensified both the global energy crisis and the challenges posed by climate change,including global warming.Currently,the increased frequency of extreme weather events a...Rapid population growth in recent decades has intensified both the global energy crisis and the challenges posed by climate change,including global warming.Currently,the increased frequency of extreme weather events and large fluctuations in ambient temperature disrupt thermal comfort and negatively impact health,driving a growing dependence on cooling and heating energy sources.Consequently,efficient thermal management has become a central focus of energy research.Traditional thermal management systems consume substantial energy,further contributing to greenhouse gas emissions.In contrast,emergent radiant thermal management technologies that rely on renewable energy have been proposed as sustainable alternatives.However,achieving year-round thermal management without additional energy input remains a formidable challenge.Recently,dynamic radiative thermal management technologies have emerged as the most promising solution,offering the potential for energy-efficient adaptation across seasonal variations.This review systematically presents recent advancements in dynamic radiative thermal management,covering fundamental principles,switching mechanisms,primary materials,and application areas.Additionally,the key challenges hindering the broader adoption of dynamic radiative thermal management technologies are discussed.By highlighting their transformative potential,this review provides insights into the design and industrial scalability of these innovations,with the ultimate aim of promoting renewable energy integration in thermal management applications.展开更多
Differentially expressed genes are thought to regulate the development and progression of oral squamous cell carcinomas （OSCC）. The purpose of this study was to screen differentially expressed mRNAs in OSCC and matc...Differentially expressed genes are thought to regulate the development and progression of oral squamous cell carcinomas （OSCC）. The purpose of this study was to screen differentially expressed mRNAs in OSCC and matched paraneoplastic normal tissues, and to explore the intrinsic mechanism of OSCC development and progres- sion. We obtained the differentially expressed mRNA expression profiles in 10 pairs of fresh-frozen OSCC tissue specimens and matched paraneoplastic normal tissue specimens by high-throughput RNA sequencing. By using Gene Ontology enrichment analysis and Kyoto Encyclopedia of Genes and Genomes （KEGG） pathway enrichment analyses, the functional significance of the differentially expressed genes were analyzed. We identified 1,120 sig- nificantly up-regulated mRNAs and 178 significantly down-regulated mRNAs in OSCC, compared to normal tissue. The differentially expressed mRNAs were involved in 20 biological processes and 68 signal pathways. Compared to adjacent normal tissue, the expression of MAGEAll was up-regulated; TCHH was down-regulated. These find- ings were verified by real-time PCR. These differentially expressed mRNAs may function as oncogenes or tumor suppressors in the development and progression of OSCC. This study provides novel insights into OSCC. However, further work is needed to determine if these differentially expressed mRNAs have potential roles as diagnostic bio- markers and candidate therapeutic targets for OSCC.展开更多
Spindle cell carcinoma is a rare highly malignant squamous cell carcinoma.Here,we describe a case of a 74-yearold Chinese female who presented with a 2-week history of pain and swelling in the left retromolar region.S...Spindle cell carcinoma is a rare highly malignant squamous cell carcinoma.Here,we describe a case of a 74-yearold Chinese female who presented with a 2-week history of pain and swelling in the left retromolar region.Surgical resection and titanium plate prosthesis were performed and histological analysis revealed spindle squamous cell carcinoma.展开更多
Composite aerogel based on sodium carboxymethyl cellulose(CMC-Na)and chitosan(CS),i.e.,CS/CMC-Na,was prepared through a sol-gel method.Then,CS/CMC-Na was used for simulating the adsorption of metal ions(Cr^(3+),Al^(3+...Composite aerogel based on sodium carboxymethyl cellulose(CMC-Na)and chitosan(CS),i.e.,CS/CMC-Na,was prepared through a sol-gel method.Then,CS/CMC-Na was used for simulating the adsorption of metal ions(Cr^(3+),Al^(3+)and Zr^(4+))produced by the tanning industry.The ad-sorption process is consistent with the Langmuir isotherm adsorption model and pseudo-second order kinetics.The maximum fitted adsorption capacities of Cr^(3+),Al^(3+),and Zr^(4+)could reach 250.0,111.1,and 100.0 mg/g,respectively.After metal ion adsorption,the obtained composite materials(CS/CMC-Na-Cr^(3+),CS/CMC-Na-Al^(3+),and CS/CMC-Na-Zr^(4+))were used as re-tanning agents in the re-tanning process to leather.The re-tanning agent could increase the shrinkage temperature of leather by up to 5℃.Compared with the traditional method,the method utilized in this study achieved the integration of mental ions-containing wastewater treatment and waste adsorbent/adsorbates recycling.展开更多
The Yarlung Zangbo Suture Zone(YZSZ)on the southern margin of the Lhasa block and the Tangjia-Sumdo ultrahigh-pressure metamorphic belt(TSMB)within the block represent natural laboratories for the study of plate tecto...The Yarlung Zangbo Suture Zone(YZSZ)on the southern margin of the Lhasa block and the Tangjia-Sumdo ultrahigh-pressure metamorphic belt(TSMB)within the block represent natural laboratories for the study of plate tectonics and oceanic slab subduction.It is generally believed that these two zones represent the remnants of the ancient oceanic crust and upper mantle of the Yarlung Zangbo Neo-Tethys(YZNT)and the Tangjia-Sumdo Paleo-Tethys(TSPT).However,the evolutionary patterns and spatiotemporal relationships of the TSPT and the YZNT have been debated.展开更多
Nowadays, diverse leather usage conditions and increasing demands from consumers challenge the leather industry. Traditional leather manufacturing is facing long-term challenges, including low-value threshold, confine...Nowadays, diverse leather usage conditions and increasing demands from consumers challenge the leather industry. Traditional leather manufacturing is facing long-term challenges, including low-value threshold, confined applica-tion fields, and environmental issues. Leather inherits all the biomimetic properties of natural skin such as flexibility, sanitation, cold resistance, biocompatibility, biodegradability, and other cross-domain functions, achieving unre-mitting attention in multi-functional bio-based materials. Series of researches have been devoted to creating and developing leather-based flexible multi-functional bio-materials, including antibacterial leather, conductive leather, flame-retardant leather, self-cleaning leather, aromatic leather, and electromagnetic shielding leather. In this review, we provide a comprehensive overview of the commonly used leather-based functional materials. Furthermore, the possible challenges for the development of functional leathers are proposed, and expected development directions of leather-based functional materials are discussed. This review may promote and inspire the emerging preparation and applications of leather for flexible functional bio-based materials.展开更多
基金Supported by Fujian Science and Technology Plan Project,No.2022J01784.
文摘BACKGROUND Differentiated thyroid cancer(DTC)often seriously impacts patients’lives.Radionuclide Iodine-131(131I)is widely used in treating patients with DTC.However,most patients know little about radionuclide therapy,and the treatment needs to be performed in a special isolation ward,which can cause anxiety and depression.AIM To explore anxiety and depression status and their influencing factors after 131I treatment in patients with DTC.METHODS A questionnaire survey was conducted among postoperative patients with DTC who received 131I treatment at our hospital from June 2020 to December 2022.General patient data were collected using a self-administered demographic characteristics questionnaire.The self-rating depression scale and self-rating anxiety scale were used to determine whether patients were worried about their symptoms and the degree of anxiety and depression.The patients were categorized into anxiety,non-anxiety,depression,and non-depression groups.Singlevariable and multiple-variable analyses were used to determine the risk factors for anxiety and depression in patients with thyroid cancer after surgery.RESULTS A total of 144 patients were included in this study.The baseline mean score of self-rating anxiety and depression scales were 50.06±16.10 and 50.96±16.55,respectively.Notably,48.62%(70/144)had anxiety and 47.22%(68/144)of the patients had depression.Sex,age,education level,marital status,household income,underlying diseases,and medication compliance significantly differed among groups(P<0.05).Furthermore,multivariate logistic regression analysis showed that education level,per capita monthly household income,and medication compliance level affected anxiety(P=0.015,0.001,and 0.001 respectively).Patient’s sex,marital status,and underlying diseases affected depression(P=0.007,0.001,and 0.009,respectively).CONCLUSION Nursing interventions aiming at reducing the risk of anxiety and depression should target unmarried female patients with low education level,low family income,underlying diseases,and poor adherence to medications.
基金the funding and generous support of the National Natural Science Foundation of China(52103263,52271249)the Key Project of International Science&Technology Cooperation of Shaanxi Province(2023-GHZD-09)+5 种基金the Key Project of Science Foundation of Education Department of Shaanxi Province(22JY011)the Key Project of Scientific Research and Development of Shaanxi Province(2023GXLH-070)the Qinchuangyuan"Scientist+Engineer"Team of Shaanxi Province(2023KXJ-069)the Key Research and Development Program of Shaanxi(2023-YBGY-488)the Sci-tech Innovation Team of Shaanxi Province(2024RS-CXTD-46)the Key Research and Development Program of Shaanxi Province(2020ZDLGY13-11).
文摘All-season thermal management with zero energy consumption and emissions is more crucial to global decarbonization over traditional energy-intensive cooling/heating systems.However,the static single thermal management for cooling or heating fails to self-regulate the temperature in dynamic seasonal temperature condition.Herein,inspired by the dual-temperature regulation function of the fur color changes on the backs and abdomens of penguins,a smart thermal management composite hydrogel(PNA@H-PM Gel)system was subtly created though an"on-demand"dual-layer structure design strategy.The PNA@H-PM Gel system features synchronous solar and thermal radiation modulation as well as tunable phase transition temperatures to meet the variable seasonal thermal requirements and energy-saving demands via self-adaptive radiative cooling and solar heating regulation.Furthermore,this system demonstrates superb modulations of both the solar reflectance(ΔR=0.74)and thermal emissivity(ΔE=0.52)in response to ambient temperature changes,highlighting efficient temperature regulation with average radiative cooling and solar heating effects of 9.6℃in summer and 6.1℃in winter,respectively.Moreover,compared to standard building baselines,the PNA@H-PM Gel presents a more substantial energy-saving cooling/heating potentials for energy-efficient buildings across various regions and climates.This novel solution,inspired by penguins in the real world,will offer a fresh approach for producing intelligent,energy-saving thermal management materials,and serve for temperature regulation under dynamic climate conditions and even throughout all seasons.
基金the Institute of Biomass&Functional Materials of Shaanxi University of Science and Technology for funding this research workfinancially supported by the National Natural Science Foundation of China(2207081675,22278257,22308209)+1 种基金the Key R&D Program of Shaanxi Province(2024SF-YBXM-586)the Project of Innovation Capability Support Program in Shaanxi Province(2024ZC-KJXX-005)。
文摘Global warming and energy crisis are two major challenges in the new-century.Wearable materials that enable all-seasonal self-adapting thermal comfort without additional energy-input attract significant attention as a solution to the increasing severity of extreme climate-change.Inspired by autologous temperature-regulation and multidimensional-sensing origins of nature-skin composed of nature collagen fibers,this study engineered a nanoscale wearable natural fibers-derived thermochromic material(TMEH-skin)for robust all-season self-adapting thermal management by tactically integrating traditional immersion and spraying methods with layer-by-layer stacking-strategy.Because of the on-demand multi-functional layer-structure design,TMEH-skin achieves spontaneous~38.16%visible lightmodulation and~95.1%infrared-emission,demonstrating outstanding double-self-switching thermal management origins by simple color-changing without additional energy-input.Moreover,TMEH-skin has gratifying tensile strength of 13.18 MPa,water vapor permeability,electrical-conductivity,and hydrophobicity,further broadening the application potential and scenarios as wearable materials.In applications for military-missions or reconnaissance behind enemy-lines,TMEH-skin robustly integrates the multi-functionalities of wearing-comfort,physiological signal-response capability for accurate transmission of Morse-code,and thermal management performances under special circumstances,indicating its tremendous potential for smart military-applications.Simulation results show that TMEH-skin has prominent energy-saving efficiency in cities with different climate zones.This study provides a new reference to the booming innovation of natural-derived wearable materials for all-seasonal self-adapting thermal management.
基金the Institute of Biomass & Functional Materials of Shaanxi University of Science and Technology for funding this research workfinancially supported by the National Natural Science Foundation of China (2207081675, 22278257, 22308209)+1 种基金the Key R&D Program of Shaanxi Province (2024SF-YBXM-586)the Project of Innovation Capability Support Program in Shaanxi Province (2024ZC-KJXX-005)
文摘Rapid population growth in recent decades has intensified both the global energy crisis and the challenges posed by climate change,including global warming.Currently,the increased frequency of extreme weather events and large fluctuations in ambient temperature disrupt thermal comfort and negatively impact health,driving a growing dependence on cooling and heating energy sources.Consequently,efficient thermal management has become a central focus of energy research.Traditional thermal management systems consume substantial energy,further contributing to greenhouse gas emissions.In contrast,emergent radiant thermal management technologies that rely on renewable energy have been proposed as sustainable alternatives.However,achieving year-round thermal management without additional energy input remains a formidable challenge.Recently,dynamic radiative thermal management technologies have emerged as the most promising solution,offering the potential for energy-efficient adaptation across seasonal variations.This review systematically presents recent advancements in dynamic radiative thermal management,covering fundamental principles,switching mechanisms,primary materials,and application areas.Additionally,the key challenges hindering the broader adoption of dynamic radiative thermal management technologies are discussed.By highlighting their transformative potential,this review provides insights into the design and industrial scalability of these innovations,with the ultimate aim of promoting renewable energy integration in thermal management applications.
基金supported by a project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD,2014-37)
文摘Differentially expressed genes are thought to regulate the development and progression of oral squamous cell carcinomas （OSCC）. The purpose of this study was to screen differentially expressed mRNAs in OSCC and matched paraneoplastic normal tissues, and to explore the intrinsic mechanism of OSCC development and progres- sion. We obtained the differentially expressed mRNA expression profiles in 10 pairs of fresh-frozen OSCC tissue specimens and matched paraneoplastic normal tissue specimens by high-throughput RNA sequencing. By using Gene Ontology enrichment analysis and Kyoto Encyclopedia of Genes and Genomes （KEGG） pathway enrichment analyses, the functional significance of the differentially expressed genes were analyzed. We identified 1,120 sig- nificantly up-regulated mRNAs and 178 significantly down-regulated mRNAs in OSCC, compared to normal tissue. The differentially expressed mRNAs were involved in 20 biological processes and 68 signal pathways. Compared to adjacent normal tissue, the expression of MAGEAll was up-regulated; TCHH was down-regulated. These find- ings were verified by real-time PCR. These differentially expressed mRNAs may function as oncogenes or tumor suppressors in the development and progression of OSCC. This study provides novel insights into OSCC. However, further work is needed to determine if these differentially expressed mRNAs have potential roles as diagnostic bio- markers and candidate therapeutic targets for OSCC.
文摘Spindle cell carcinoma is a rare highly malignant squamous cell carcinoma.Here,we describe a case of a 74-yearold Chinese female who presented with a 2-week history of pain and swelling in the left retromolar region.Surgical resection and titanium plate prosthesis were performed and histological analysis revealed spindle squamous cell carcinoma.
基金financial support of the Science and Technology Project of Quanzhou City(No.2024G03)Na-tional Natural Science Foundation of China(No.22478235)+1 种基金National Natural Science Foundation of China(No.22078183No.22108165).
文摘Composite aerogel based on sodium carboxymethyl cellulose(CMC-Na)and chitosan(CS),i.e.,CS/CMC-Na,was prepared through a sol-gel method.Then,CS/CMC-Na was used for simulating the adsorption of metal ions(Cr^(3+),Al^(3+)and Zr^(4+))produced by the tanning industry.The ad-sorption process is consistent with the Langmuir isotherm adsorption model and pseudo-second order kinetics.The maximum fitted adsorption capacities of Cr^(3+),Al^(3+),and Zr^(4+)could reach 250.0,111.1,and 100.0 mg/g,respectively.After metal ion adsorption,the obtained composite materials(CS/CMC-Na-Cr^(3+),CS/CMC-Na-Al^(3+),and CS/CMC-Na-Zr^(4+))were used as re-tanning agents in the re-tanning process to leather.The re-tanning agent could increase the shrinkage temperature of leather by up to 5℃.Compared with the traditional method,the method utilized in this study achieved the integration of mental ions-containing wastewater treatment and waste adsorbent/adsorbates recycling.
基金supported by the Science and Technology Research Program of Chongqing Municipal Education Commission(Grant No.KJQN202404310,KJQN202304302)National Natural Science Foundation of China(41972118).
文摘The Yarlung Zangbo Suture Zone(YZSZ)on the southern margin of the Lhasa block and the Tangjia-Sumdo ultrahigh-pressure metamorphic belt(TSMB)within the block represent natural laboratories for the study of plate tectonics and oceanic slab subduction.It is generally believed that these two zones represent the remnants of the ancient oceanic crust and upper mantle of the Yarlung Zangbo Neo-Tethys(YZNT)and the Tangjia-Sumdo Paleo-Tethys(TSPT).However,the evolutionary patterns and spatiotemporal relationships of the TSPT and the YZNT have been debated.
基金the National Natural Science Foundation of China(2207081675)Science and Technology Project of Xianyang City(Grant 2018k02-28)+3 种基金Fellowship of China Postdoctoral Science Foundation(2021M692000)Key R&D Program of Shaanxi Province(2022GY-272)Young Talent Support Program Project of Shaanxi University Science and Technology Association(20200424)Department of education’s Production-Study-Research combined innovation Funding-“Blue fire plan(Huizhou)”of 2018(CXZJHZ201801).
文摘Nowadays, diverse leather usage conditions and increasing demands from consumers challenge the leather industry. Traditional leather manufacturing is facing long-term challenges, including low-value threshold, confined applica-tion fields, and environmental issues. Leather inherits all the biomimetic properties of natural skin such as flexibility, sanitation, cold resistance, biocompatibility, biodegradability, and other cross-domain functions, achieving unre-mitting attention in multi-functional bio-based materials. Series of researches have been devoted to creating and developing leather-based flexible multi-functional bio-materials, including antibacterial leather, conductive leather, flame-retardant leather, self-cleaning leather, aromatic leather, and electromagnetic shielding leather. In this review, we provide a comprehensive overview of the commonly used leather-based functional materials. Furthermore, the possible challenges for the development of functional leathers are proposed, and expected development directions of leather-based functional materials are discussed. This review may promote and inspire the emerging preparation and applications of leather for flexible functional bio-based materials.
