In order to characterize sleep and the cognitive patterns in patients with acute minor thalamic infarction （AMTI）, we enrolled 27 patients with AMTI and 12 mat- ched healthy individuals. Questionnaires about sleep a...In order to characterize sleep and the cognitive patterns in patients with acute minor thalamic infarction （AMTI）, we enrolled 27 patients with AMTI and 12 mat- ched healthy individuals. Questionnaires about sleep and cognition as well as polysomnography （PSG） were performed on days 14 and 90 post-stroke. Compared to heal- thy controls, in patients with AMTI, hyposomnia was more prevalent; sleep architecture was disrupted as indicated by decreased sleep efficiency, increased sleep latency, and decreased non-rapid eye movement sleep stages 2 and 3; more sleep-related breathing disorders occurred; and cog- nitive functions were worse, especially memory. While sleep apnea and long-delay memory recovered to a large extent in the patients, other sleep and cognitive function deficit often persisted. Patients with AMTI are at an increased risk for hyposomnia, sleep structure disturbance, sleep apnea, and memory deficits. Although these abnormalities improved over time, the slow and incomplete improvement suggest that early management should be considered in these patients.展开更多
基金supported by the Health Industry Key Research Project of Tianjin Municipality,China(12KG132)the Science and Technology Plan Project of Tianjin Municipality,China(13ZCZDSY01900)
文摘In order to characterize sleep and the cognitive patterns in patients with acute minor thalamic infarction （AMTI）, we enrolled 27 patients with AMTI and 12 mat- ched healthy individuals. Questionnaires about sleep and cognition as well as polysomnography （PSG） were performed on days 14 and 90 post-stroke. Compared to heal- thy controls, in patients with AMTI, hyposomnia was more prevalent; sleep architecture was disrupted as indicated by decreased sleep efficiency, increased sleep latency, and decreased non-rapid eye movement sleep stages 2 and 3; more sleep-related breathing disorders occurred; and cog- nitive functions were worse, especially memory. While sleep apnea and long-delay memory recovered to a large extent in the patients, other sleep and cognitive function deficit often persisted. Patients with AMTI are at an increased risk for hyposomnia, sleep structure disturbance, sleep apnea, and memory deficits. Although these abnormalities improved over time, the slow and incomplete improvement suggest that early management should be considered in these patients.
