Personal care products(PCPs)are a class of emerging pollutants that have attracted public concern owing to their harmful effects on humans and the environment.Biomonitoring data is valuable for insight the levels of P...Personal care products(PCPs)are a class of emerging pollutants that have attracted public concern owing to their harmful effects on humans and the environment.Biomonitoring data is valuable for insight the levels of PCPs in the human body and can be crucial for identifying potential health hazards.To gain a better understanding of timely exposure profiles and health risk of reproductive-age population to PCPs,we determined six parabens,six benzophenone-type ultraviolet filters,and three disinfectants in 256 urine samples collected from young adults aged 18-44 years in Beijing,China.The urinary levels of benzophenone-3(BP-3)and 4-hydroxybenzophenone(4-OHBP)were significantly higher in summer compared to winter,suggesting these compounds have different seasonal usage patterns.Moreover,the total concentration of 15 PCPs in female was 430 ng/mL,approximately two times higher than that in male.P-chloro-m-xylenol(PCMX),as a new type of antibacterial agent,has the greatest level among all target analytes,indicating the increasingly use of this antibacterial alternative recently.Five potential influencing factors that lead to the elevated exposure level of PCPs were identified.Over 19%of the target population had a high hazard index value(greater than 1)which was attributed to exposure to propyl paraben(PrP),benzophenone-1(BP-1),BP-3 and PCMX,indicating that PCPs may pose a relatively high exposure risk at environmental levels that should be a cause for concern.展开更多
基金supported by the National Natural Science Foundation of China (No.22106154).
文摘Personal care products(PCPs)are a class of emerging pollutants that have attracted public concern owing to their harmful effects on humans and the environment.Biomonitoring data is valuable for insight the levels of PCPs in the human body and can be crucial for identifying potential health hazards.To gain a better understanding of timely exposure profiles and health risk of reproductive-age population to PCPs,we determined six parabens,six benzophenone-type ultraviolet filters,and three disinfectants in 256 urine samples collected from young adults aged 18-44 years in Beijing,China.The urinary levels of benzophenone-3(BP-3)and 4-hydroxybenzophenone(4-OHBP)were significantly higher in summer compared to winter,suggesting these compounds have different seasonal usage patterns.Moreover,the total concentration of 15 PCPs in female was 430 ng/mL,approximately two times higher than that in male.P-chloro-m-xylenol(PCMX),as a new type of antibacterial agent,has the greatest level among all target analytes,indicating the increasingly use of this antibacterial alternative recently.Five potential influencing factors that lead to the elevated exposure level of PCPs were identified.Over 19%of the target population had a high hazard index value(greater than 1)which was attributed to exposure to propyl paraben(PrP),benzophenone-1(BP-1),BP-3 and PCMX,indicating that PCPs may pose a relatively high exposure risk at environmental levels that should be a cause for concern.
