Changes of plasma C-reactive protein in patients with craniocerebral injury before and after hyperbaric oxygenation： A randomly controlled study BACKGROUND： Plasma inflammatory factor, such as C-reactive prot...Changes of plasma C-reactive protein in patients with craniocerebral injury before and after hyperbaric oxygenation： A randomly controlled study BACKGROUND： Plasma inflammatory factor, such as C-reactive protein, whose content is regarded as a sensitively pathological marked protein and quantitative indexes of central nervous system injury, has been paid more and more attention in clinic. OBJECTIVE： To observe the effects and clinical significance of C-reactive protein in patients with craniocerebral injury after hyperbaric oxygenation. DESIGN： Randomized controlled study. SETTING： Departments of Neurosurgery, Laboratory and Hyperbaric Oxygen, the Second Affiliated Hospital, Medical College of Shantou University. PARTICIPANTS： A total of 60 patients with craniocerebral injury were selected from Department of Neurosurgery, the Second Affiliated Hospital, Medical College of Shantou University from October 2006 to April 2007. There were 37 males and 23 females and the mean age was 26 years. All subjects were certainly diagnosed as history of craniocerebral injury. Patients hospitalized at 24 hours after injury, Glasgow Coma Score ranged from 3 to 12 points, and all patients were certainly diagnosed with CT or MR scanning. Patients and their relatives provided confirmed consent. All the subjects were randomly divided into hyperbaric oxygenation group and control group with 30 in each group. METHODS： Patients in the control group were treated with routinely neurosurgical therapy after hospitalization; however, based the same basic treatment in the control group, patients in the hyperbaric oxygenation group received hyperbaric oxygenation by using iced-wheel four-door 2-cabin air-compression chamber （made in Yantai） from 24 hours to 10 days after operation or injury. After entering the cabin, patients who had a clear consciousness breathed the oxygen by using face mask; contrarily, patients directly breathed the oxygen. Therapeutic project： Expression was increased for about 15–20 minutes, maintained for about 70–80 minutes, and decreased for 20 minutes. Otherwise, pressure was maintained from 0.2 to 0.25 MPa. Hyperbaric oxygenation took an hour for once a day and 10 times were regarded as a course. Venous blood was collected before treatment and on the next day of the first course end. Content of C-reactive protein in plasma was measured with immune turbidimetry in hyperbaric oxygenation group; in addition, content of C-reactive protein in plasma was directly measured with the same method at the corresponding time in the control group. If the content was less or equal to 8 mg/L, it was regarded as normal value. Effects of the two groups were evaluated based on Glasgow Coma Score before and after treatment. MAIN OUTCOME MEASURES： Content of plasma C-reactive protein and Glasgow Coma Score in the two groups before and after treatment. RESULTS： All 60 patients were involved in the final analysis. ① Content of plasma C-reactive protein： The two contents were obviously higher than normal value after craniocerebral injury. There was no significant difference in the two groups before treatment （P 〉 0.05）, but both contents were decreased after treatment, and there was significant difference between HBOT group and control group after treatment （t =4.756, P 〈 0.01）. In addition, there was significant difference in hyperbaric oxygen therapy group before and after treatment （t =5.236, P 〈 0.01）. ② Glasgow Coma Score： There was no significant difference in the two groups before treatment （P 〉 0.05）, but scores were increased in both groups after treatment （t =9.92, 2.51, P 〈 0.01, 0.05）; on the other hand, therefore, there was significant difference between the two groupsafter treatment （t =9.21, P 〈 0.01）. CONCLUSION： Hyperbaric oxygenation can remarkably decrease content of plasma C-reactive protein in patients with craniocerebral injury at the phase of stress.展开更多
Purpose:To investigate the clinical characteristics and therapeutic effects of vitrectomy in patients with perforating eye injuries with foreign bodies at the exit wound in the posterior global wall.Methods:.Fifty-two...Purpose:To investigate the clinical characteristics and therapeutic effects of vitrectomy in patients with perforating eye injuries with foreign bodies at the exit wound in the posterior global wall.Methods:.Fifty-two cases,diagnosed with perforating eye injury with foreign bodies at the exit of the posterior global wall and admitted to our hospital between June 2010 and June2013,were enrolled in this study.All patients underwent vitrectomy and removal of intraocular foreign bodies and were followed up for 6 to 24 months.The causes of injuries were analyzed and postoperative visual acuity and overall treatment efficacy were evaluated.Results:Intraocular foreign bodies were successfully removed in all cases.The incidence of postoperative complication was low.Among 52 subjects,46 showed alleviated symptoms after treatment with an overall efficacy of 88.46%.Conclusion:.Perforating eye injuries combined with residual foreign bodies in the posterior global wall are commonly observed in young people who perform physical labor.Vitrectomy has a high efficacy for the treatment of perforating eye injuries complicated with foreign bodies located at the posterior global wall,with a low incidence of postoperative complications.展开更多
Purpose: To investigate the efficacy of progressive addition lenses on the treatment of ametropia and loss of accomodation after the single eye's IOL implantation. Methods:.Eighty four patients undergoing IOL impl...Purpose: To investigate the efficacy of progressive addition lenses on the treatment of ametropia and loss of accomodation after the single eye's IOL implantation. Methods:.Eighty four patients undergoing IOL implantation in single eyes were prescribed with progressive addition lenses for ametropia correction and regularly followed up to observe subsequent correction effect. Results:.Among these 84 patients,.72 could comfortably adapt to the use of progressive addition lenses to improve visual acuity and accomondation,while the remaining 12 patients failed to accomodate the usage of progressive addition lenses. Conclusion:.Wearing progressive addition lenses acts as a relatively feasible approach to improve visual acuity and alleviate disorders of accomodation for patients who underwent IOL implantation in single eyes..The patients should be prescribed with progressive lenses under professional instructions and guidance.展开更多
Background: Different visual acuity chart can be targeted to evaluate the visual function of patients with different eye diseases. We conducted a comparative analysis of the digital logarithm of the minimum angle of r...Background: Different visual acuity chart can be targeted to evaluate the visual function of patients with different eye diseases. We conducted a comparative analysis of the digital logarithm of the minimum angle of resolution(Log MAR) vision chart and the standard logarithmic vision chart for the measurement of visual acuity after retinal detachment surgery.Methods: We used the digital Log MAR vision chart and the standard logarithmic vision chart to measure the visual acuity of 100 patients(100 eyes) who underwent retinal detachment surgery at our hospital using the Log MAR recording method and compared the dif erences between the mean measurements obtained by both methods for all patients and for different age groups.Results: When all of the patients were analyzed, the mean visual acuity dif ered between the digital Log MAR vision chart and the standard logarithmic vision chart by –0.07 Log MAR units. No signii cant difference was observed in the mean visual acuity between the two vision charts in the 10-20 year and 21-40 year age groups(P>0.05), while a signii cant difference was observed in post-operative mean visual acuity between the two vision charts for patients aged 41-65 years(P<0.05).Conclusions: Both the digital Log MAR vision chart and the standard vision chart were effective and reliable for the measurement of visual acuity. The visual acuity measured by the standard vision chart was higher than that measured by the digital Log MAR vision chart. We recommend using the digital Log MAR vision chart as the preferred chart for measuring visual acuity after retinal detachment surgery.展开更多
Purpose: To evaluate the applicability of different visual acuity charts for outpatient pediatric visual tests.Methods: Fifty-three children(53 eyes) aged 4-8 years undergoing visual acuity tests as outpatients were r...Purpose: To evaluate the applicability of different visual acuity charts for outpatient pediatric visual tests.Methods: Fifty-three children(53 eyes) aged 4-8 years undergoing visual acuity tests as outpatients were randomly selected for this study. The best corrected visual acuity(BCVA)of the eye with better visual acuity was measured for each child using the digital LogMAR visual chart,.the ETDRS visual chart,.and a new standard logarithm visual chart;.all measurements were repeated twice and the BCVA was recorded. Paired comparisons were made between the LogMAR visual acuity chart and ETDRS chart measurements or between the ETDRS chart and logarithm visual acuity chart measurements for statistical analysis of the differences in measurement of visual acuity..The results of different measurements by the same chart were compared to evaluate the consistency of the measurement results..Bland-Altman analysis was employed to evaluate the most suitable chart for outpatient measurement of visual acuity in children.Results:.Bland-Altman analysis revealed that the mean visual acuity measured was.(0.447 ±0.017 LogMAR).by the digital LogMAR chart,.(0.301±0.024 LogMAR).by the standard logarithm visual acuity chart, and(0.309 ±0.018 LogMAR) by the ETDRS visual acuity chart. The BCVA was significantly lower when measured by the LogMAR visual acuity chart than by the ETDRS chart(P<0.01). The BCVA was slightly higher when measured by the logarithm visual acuity chart than by the ETDRS chart, but the difference was not statistically sig nificant(P>0.05)..The Bland-Altman plot showed that the highest consistency was obtained with the digital LogMAR chart,with a difference between two repeated measurements of 0.068 LogMAR,.compared to 0.090 and 0.072 LogMAR for the logarithm and ETDRS visual acuity charts, respectively.Conclusion: All three types of visual acuity charts are appli-cable for outpatient measurement of pediatric visual acuity.The ETDRS and logarithm visual acuity charts have a higher consistency, but the LogMAR visual acuity chart shows better reproducibility..Consequently,.it is difficult to identify and distinguish which acuity chart is most suitable for cooperative children.展开更多
文摘Changes of plasma C-reactive protein in patients with craniocerebral injury before and after hyperbaric oxygenation： A randomly controlled study BACKGROUND： Plasma inflammatory factor, such as C-reactive protein, whose content is regarded as a sensitively pathological marked protein and quantitative indexes of central nervous system injury, has been paid more and more attention in clinic. OBJECTIVE： To observe the effects and clinical significance of C-reactive protein in patients with craniocerebral injury after hyperbaric oxygenation. DESIGN： Randomized controlled study. SETTING： Departments of Neurosurgery, Laboratory and Hyperbaric Oxygen, the Second Affiliated Hospital, Medical College of Shantou University. PARTICIPANTS： A total of 60 patients with craniocerebral injury were selected from Department of Neurosurgery, the Second Affiliated Hospital, Medical College of Shantou University from October 2006 to April 2007. There were 37 males and 23 females and the mean age was 26 years. All subjects were certainly diagnosed as history of craniocerebral injury. Patients hospitalized at 24 hours after injury, Glasgow Coma Score ranged from 3 to 12 points, and all patients were certainly diagnosed with CT or MR scanning. Patients and their relatives provided confirmed consent. All the subjects were randomly divided into hyperbaric oxygenation group and control group with 30 in each group. METHODS： Patients in the control group were treated with routinely neurosurgical therapy after hospitalization; however, based the same basic treatment in the control group, patients in the hyperbaric oxygenation group received hyperbaric oxygenation by using iced-wheel four-door 2-cabin air-compression chamber （made in Yantai） from 24 hours to 10 days after operation or injury. After entering the cabin, patients who had a clear consciousness breathed the oxygen by using face mask; contrarily, patients directly breathed the oxygen. Therapeutic project： Expression was increased for about 15–20 minutes, maintained for about 70–80 minutes, and decreased for 20 minutes. Otherwise, pressure was maintained from 0.2 to 0.25 MPa. Hyperbaric oxygenation took an hour for once a day and 10 times were regarded as a course. Venous blood was collected before treatment and on the next day of the first course end. Content of C-reactive protein in plasma was measured with immune turbidimetry in hyperbaric oxygenation group; in addition, content of C-reactive protein in plasma was directly measured with the same method at the corresponding time in the control group. If the content was less or equal to 8 mg/L, it was regarded as normal value. Effects of the two groups were evaluated based on Glasgow Coma Score before and after treatment. MAIN OUTCOME MEASURES： Content of plasma C-reactive protein and Glasgow Coma Score in the two groups before and after treatment. RESULTS： All 60 patients were involved in the final analysis. ① Content of plasma C-reactive protein： The two contents were obviously higher than normal value after craniocerebral injury. There was no significant difference in the two groups before treatment （P 〉 0.05）, but both contents were decreased after treatment, and there was significant difference between HBOT group and control group after treatment （t =4.756, P 〈 0.01）. In addition, there was significant difference in hyperbaric oxygen therapy group before and after treatment （t =5.236, P 〈 0.01）. ② Glasgow Coma Score： There was no significant difference in the two groups before treatment （P 〉 0.05）, but scores were increased in both groups after treatment （t =9.92, 2.51, P 〈 0.01, 0.05）; on the other hand, therefore, there was significant difference between the two groupsafter treatment （t =9.21, P 〈 0.01）. CONCLUSION： Hyperbaric oxygenation can remarkably decrease content of plasma C-reactive protein in patients with craniocerebral injury at the phase of stress.
文摘Purpose:To investigate the clinical characteristics and therapeutic effects of vitrectomy in patients with perforating eye injuries with foreign bodies at the exit wound in the posterior global wall.Methods:.Fifty-two cases,diagnosed with perforating eye injury with foreign bodies at the exit of the posterior global wall and admitted to our hospital between June 2010 and June2013,were enrolled in this study.All patients underwent vitrectomy and removal of intraocular foreign bodies and were followed up for 6 to 24 months.The causes of injuries were analyzed and postoperative visual acuity and overall treatment efficacy were evaluated.Results:Intraocular foreign bodies were successfully removed in all cases.The incidence of postoperative complication was low.Among 52 subjects,46 showed alleviated symptoms after treatment with an overall efficacy of 88.46%.Conclusion:.Perforating eye injuries combined with residual foreign bodies in the posterior global wall are commonly observed in young people who perform physical labor.Vitrectomy has a high efficacy for the treatment of perforating eye injuries complicated with foreign bodies located at the posterior global wall,with a low incidence of postoperative complications.
文摘Purpose: To investigate the efficacy of progressive addition lenses on the treatment of ametropia and loss of accomodation after the single eye's IOL implantation. Methods:.Eighty four patients undergoing IOL implantation in single eyes were prescribed with progressive addition lenses for ametropia correction and regularly followed up to observe subsequent correction effect. Results:.Among these 84 patients,.72 could comfortably adapt to the use of progressive addition lenses to improve visual acuity and accomondation,while the remaining 12 patients failed to accomodate the usage of progressive addition lenses. Conclusion:.Wearing progressive addition lenses acts as a relatively feasible approach to improve visual acuity and alleviate disorders of accomodation for patients who underwent IOL implantation in single eyes..The patients should be prescribed with progressive lenses under professional instructions and guidance.
文摘Background: Different visual acuity chart can be targeted to evaluate the visual function of patients with different eye diseases. We conducted a comparative analysis of the digital logarithm of the minimum angle of resolution(Log MAR) vision chart and the standard logarithmic vision chart for the measurement of visual acuity after retinal detachment surgery.Methods: We used the digital Log MAR vision chart and the standard logarithmic vision chart to measure the visual acuity of 100 patients(100 eyes) who underwent retinal detachment surgery at our hospital using the Log MAR recording method and compared the dif erences between the mean measurements obtained by both methods for all patients and for different age groups.Results: When all of the patients were analyzed, the mean visual acuity dif ered between the digital Log MAR vision chart and the standard logarithmic vision chart by –0.07 Log MAR units. No signii cant difference was observed in the mean visual acuity between the two vision charts in the 10-20 year and 21-40 year age groups(P>0.05), while a signii cant difference was observed in post-operative mean visual acuity between the two vision charts for patients aged 41-65 years(P<0.05).Conclusions: Both the digital Log MAR vision chart and the standard vision chart were effective and reliable for the measurement of visual acuity. The visual acuity measured by the standard vision chart was higher than that measured by the digital Log MAR vision chart. We recommend using the digital Log MAR vision chart as the preferred chart for measuring visual acuity after retinal detachment surgery.
文摘Purpose: To evaluate the applicability of different visual acuity charts for outpatient pediatric visual tests.Methods: Fifty-three children(53 eyes) aged 4-8 years undergoing visual acuity tests as outpatients were randomly selected for this study. The best corrected visual acuity(BCVA)of the eye with better visual acuity was measured for each child using the digital LogMAR visual chart,.the ETDRS visual chart,.and a new standard logarithm visual chart;.all measurements were repeated twice and the BCVA was recorded. Paired comparisons were made between the LogMAR visual acuity chart and ETDRS chart measurements or between the ETDRS chart and logarithm visual acuity chart measurements for statistical analysis of the differences in measurement of visual acuity..The results of different measurements by the same chart were compared to evaluate the consistency of the measurement results..Bland-Altman analysis was employed to evaluate the most suitable chart for outpatient measurement of visual acuity in children.Results:.Bland-Altman analysis revealed that the mean visual acuity measured was.(0.447 ±0.017 LogMAR).by the digital LogMAR chart,.(0.301±0.024 LogMAR).by the standard logarithm visual acuity chart, and(0.309 ±0.018 LogMAR) by the ETDRS visual acuity chart. The BCVA was significantly lower when measured by the LogMAR visual acuity chart than by the ETDRS chart(P<0.01). The BCVA was slightly higher when measured by the logarithm visual acuity chart than by the ETDRS chart, but the difference was not statistically sig nificant(P>0.05)..The Bland-Altman plot showed that the highest consistency was obtained with the digital LogMAR chart,with a difference between two repeated measurements of 0.068 LogMAR,.compared to 0.090 and 0.072 LogMAR for the logarithm and ETDRS visual acuity charts, respectively.Conclusion: All three types of visual acuity charts are appli-cable for outpatient measurement of pediatric visual acuity.The ETDRS and logarithm visual acuity charts have a higher consistency, but the LogMAR visual acuity chart shows better reproducibility..Consequently,.it is difficult to identify and distinguish which acuity chart is most suitable for cooperative children.
