Elastic electronics are increasingly prevalent in information storage,smart sensing and health monitoring due to their softness,stretchability and portability.Wearable electronic devices should possess elasticity and ...Elastic electronics are increasingly prevalent in information storage,smart sensing and health monitoring due to their softness,stretchability and portability.Wearable electronic devices should possess elasticity and stretchability that align with biological tissues.Specifically,their materials should be capable of elastic strain up to 50–80%,while the devices themselves must maintain electric stability under strains that accommodate body movements[1].展开更多
In order to have an overview of implementation of the subsidy policy for purchase of plant protection machinery in Fujian Province, based on the questionnaire data on Fujian Province, we use Logit model to conduct emp...In order to have an overview of implementation of the subsidy policy for purchase of plant protection machinery in Fujian Province, based on the questionnaire data on Fujian Province, we use Logit model to conduct empirical analysis of factors influencing farmers' willingness to participate in the subsidy policy for purchase of plant protection machinery. Research results show that there are 69.4% of farmers willing to participate in the subsidy policy for purchase of plant protection machinery; farmers' growing area has a significant impact on the willingness to participate in the subsidy policy for purchase of plant protection machinery, and there is negative correlation; educational level, experience in planting, family farming pure income all have a significant positive impact on the willingness to participate in the subsidy policy.展开更多
Pesticides are widely used in agriculture,public health,and residences to control pests and insects.The safety of exposure to pesticides has raised concerns due to their presence in the environment and their potential...Pesticides are widely used in agriculture,public health,and residences to control pests and insects.The safety of exposure to pesticides has raised concerns due to their presence in the environment and their potential effects on human health.The ovary is the major female reproductive organ and is considered a potential target organ for pesticide toxicity.This comprehensive Review examines the adverse effects of pesticide exposure on the ovary based on evidence from human biomonitoring,epidemiological studies,and toxicological studies.Epidemiological studies have shown that pesticide exposures are associated with early/delayed menarche,menstrual cycle disorders,early menopause,long time to pregnancy,polycystic ovary syndrome,primary ovarian insufficiency,infertility,and implantation failure in women.Both in vivo and in vitro studies have shown that exposure to pesticides disrupts the estrous cycle,reduces the follicle pool,alters hormone levels,and impairs oocyte maturation.Mechanisms of action of pesticides on ovarian function include effects on steroid receptors,hormone synthesis,oxidative stress,inflammation,epigenetic modifications,and signaling pathways.Gaps in knowledge and further research needs include prospective cohort studies with adequate sample sizes to elucidate the effects of different classes of pesticides(especially emerging insecticides,herbicides and fungicides)and mixture exposures on ovarian health,the development of effective toxicological models that can approximate or simulate realistic human exposure scenarios,and the translation of toxicological findings into measurable indicators that can be used in human health risk assessment.In summary,this Review aims to improve the understanding of the risk to women’s reproductive health from exposures to pesticides and to provide insights into strategies for preventing and managing reproductive health risks.展开更多
Background The correlation between metals and hypertension,such as sodium,zinc,potassium,and magnesium,has been confirmed,while the relationship between aluminum and hypertension is not very clear.This study aimed to ...Background The correlation between metals and hypertension,such as sodium,zinc,potassium,and magnesium,has been confirmed,while the relationship between aluminum and hypertension is not very clear.This study aimed to evaluate the correlation between plasma aluminum and hypertension in electrolytic aluminum workers by the Bayesian networks(BN).Methods In 2019,476 male workers in an aluminum factory were investigated.The plasma aluminum concentration of workers was measured by inductively coupled plasma mass spectrometry.The influencing factors on the prevalence of hypertension were analyzed by the BN.Results The prevalence of hypertension was 23.9%in 476 male workers.The risk of hypertension from plasma aluminum in the Q2,Q3,and Q4 groups was 5.20(1.90–14.25),6.92(2.51–19.08),and 7.33(2.69–20.01),respectively,compared with that in the Q1 group.The risk of hypertension from the duration of exposure to aluminum of>10 years was 2.23(1.09–4.57),compared without aluminum exposure.Area under the curve was 0.80 of plasma aluminum and the duration of exposure to aluminum was based on covariates,indicating that aluminum exposure had important predictive value in the prevalence of hypertension in the occupational population.The results of the study using the BN model showed that if the plasma aluminum of all participants was higher than Q4(≥47.86µg/L)and the participants were drinking,smoking,diabetes,central obesity,dyslipidemia,and aged>50 years,the proportion of hypertension was 71.2%.Conclusions The prevalence of hypertension increased significantly with the increase of plasma aluminum level.展开更多
Dear Editor,Pheochromocytomas are rare neuroendocrine tumors originating from chromaffin cells in the adrenal medulla(Neumann et al., 2019). A number of case reports and small cohorts have reported the association bet...Dear Editor,Pheochromocytomas are rare neuroendocrine tumors originating from chromaffin cells in the adrenal medulla(Neumann et al., 2019). A number of case reports and small cohorts have reported the association between dysglycemia and pheochromocytomas(Elenkova et al., 2020;Khatiwada et al., 2020;Krumeich et al., 2021). However, there are few large sample studies reporting the outcomes of dysglycemia in patients with pheochromocytomas after resection.展开更多
基金supported by generous grants from the Natural Science Foundation of Zhejiang Province(LR24E030003)Zhejiang Province Qianjiang Talent Program(ZJ-QJRC-2020-32).
文摘Elastic electronics are increasingly prevalent in information storage,smart sensing and health monitoring due to their softness,stretchability and portability.Wearable electronic devices should possess elasticity and stretchability that align with biological tissues.Specifically,their materials should be capable of elastic strain up to 50–80%,while the devices themselves must maintain electric stability under strains that accommodate body movements[1].
基金Supported by Key Project of Fujian Provincial Department of Education(JA11131S)
文摘In order to have an overview of implementation of the subsidy policy for purchase of plant protection machinery in Fujian Province, based on the questionnaire data on Fujian Province, we use Logit model to conduct empirical analysis of factors influencing farmers' willingness to participate in the subsidy policy for purchase of plant protection machinery. Research results show that there are 69.4% of farmers willing to participate in the subsidy policy for purchase of plant protection machinery; farmers' growing area has a significant impact on the willingness to participate in the subsidy policy for purchase of plant protection machinery, and there is negative correlation; educational level, experience in planting, family farming pure income all have a significant positive impact on the willingness to participate in the subsidy policy.
基金supported by National Key R&D Program of China(2022YFE0134900)the National Natural Science Foundation of China(22376184)Zhejiang Provincial Natural Science Foundation(LZ25B070002).
文摘Pesticides are widely used in agriculture,public health,and residences to control pests and insects.The safety of exposure to pesticides has raised concerns due to their presence in the environment and their potential effects on human health.The ovary is the major female reproductive organ and is considered a potential target organ for pesticide toxicity.This comprehensive Review examines the adverse effects of pesticide exposure on the ovary based on evidence from human biomonitoring,epidemiological studies,and toxicological studies.Epidemiological studies have shown that pesticide exposures are associated with early/delayed menarche,menstrual cycle disorders,early menopause,long time to pregnancy,polycystic ovary syndrome,primary ovarian insufficiency,infertility,and implantation failure in women.Both in vivo and in vitro studies have shown that exposure to pesticides disrupts the estrous cycle,reduces the follicle pool,alters hormone levels,and impairs oocyte maturation.Mechanisms of action of pesticides on ovarian function include effects on steroid receptors,hormone synthesis,oxidative stress,inflammation,epigenetic modifications,and signaling pathways.Gaps in knowledge and further research needs include prospective cohort studies with adequate sample sizes to elucidate the effects of different classes of pesticides(especially emerging insecticides,herbicides and fungicides)and mixture exposures on ovarian health,the development of effective toxicological models that can approximate or simulate realistic human exposure scenarios,and the translation of toxicological findings into measurable indicators that can be used in human health risk assessment.In summary,this Review aims to improve the understanding of the risk to women’s reproductive health from exposures to pesticides and to provide insights into strategies for preventing and managing reproductive health risks.
基金Natural Science Foundationof Shanxi Province,Grant/Award Numbers:202103021224226,202303021211255Shanxi Scholarship Council of China,Grant/Award Number:2021-084Shanxi Health Commission Key Laboratory of Nervous System Disease Prevention and Treatment,Grant/Award Number:2020SY20。
文摘Background The correlation between metals and hypertension,such as sodium,zinc,potassium,and magnesium,has been confirmed,while the relationship between aluminum and hypertension is not very clear.This study aimed to evaluate the correlation between plasma aluminum and hypertension in electrolytic aluminum workers by the Bayesian networks(BN).Methods In 2019,476 male workers in an aluminum factory were investigated.The plasma aluminum concentration of workers was measured by inductively coupled plasma mass spectrometry.The influencing factors on the prevalence of hypertension were analyzed by the BN.Results The prevalence of hypertension was 23.9%in 476 male workers.The risk of hypertension from plasma aluminum in the Q2,Q3,and Q4 groups was 5.20(1.90–14.25),6.92(2.51–19.08),and 7.33(2.69–20.01),respectively,compared with that in the Q1 group.The risk of hypertension from the duration of exposure to aluminum of>10 years was 2.23(1.09–4.57),compared without aluminum exposure.Area under the curve was 0.80 of plasma aluminum and the duration of exposure to aluminum was based on covariates,indicating that aluminum exposure had important predictive value in the prevalence of hypertension in the occupational population.The results of the study using the BN model showed that if the plasma aluminum of all participants was higher than Q4(≥47.86µg/L)and the participants were drinking,smoking,diabetes,central obesity,dyslipidemia,and aged>50 years,the proportion of hypertension was 71.2%.Conclusions The prevalence of hypertension increased significantly with the increase of plasma aluminum level.
基金supported by the National Key Research and Development Program of China(2016YFC1300100)the National Natural Science Foundation of China(81974042)+1 种基金the CAMS Innovation Fund for Medical Sciences(2022-I2M-C&T-A-010,2022I2M-C&T-A-011,and 2022-I2M-C&T-B-041)the Nonprofit Central Research Institute Fund of Chinese Academy of Medical Sciences(2019XK320057 and 2019XK320058)。
基金supported by the National Key Research and Development Program of China(2016YFC1300100)the CAMS Innovation Fund for Medical Sciences(2022-I2M-C&T-A-010,2022-I2MC&T-B-041)National High Level Hospital Clinical Research Funding(2022-PUMCH-D-005,2022-PUMCH-B-110)。
文摘Dear Editor,Pheochromocytomas are rare neuroendocrine tumors originating from chromaffin cells in the adrenal medulla(Neumann et al., 2019). A number of case reports and small cohorts have reported the association between dysglycemia and pheochromocytomas(Elenkova et al., 2020;Khatiwada et al., 2020;Krumeich et al., 2021). However, there are few large sample studies reporting the outcomes of dysglycemia in patients with pheochromocytomas after resection.
