This study analyzed the effects of male age and abstinence time on semen quality and explored the best abstinence time for Chinese males among different age groups.Semen parameters,including sperm kinetics,morphology,...This study analyzed the effects of male age and abstinence time on semen quality and explored the best abstinence time for Chinese males among different age groups.Semen parameters,including sperm kinetics,morphology,and DNA fragmentation index(DFI),were reviewed from 2952 men.Samples were divided into six age groups(≤25 years,26–30 years,31–35 years,36–40 years,41–45 years,and>45 years)and were divided into six groups according to different abstinence time(2 days,3 days,4 days,5 days,6 days,and 7 days).The differences in semen quality between the groups were compared,and the effect of age and abstinence time on semen quality was analyzed.Significant differences were observed in semen volume,progressive motility(PR),and DFI among the age groups(all P<0.05),and no significant differences were observed in sperm morphological parameters(all P>0.05).There were significant differences in semen volume,PR,and DFI among different abstinence time groups(all P<0.05)and no significant differences in sperm morphological parameters(all P>0.05).Pearson analysis showed that male age and abstinence time were both significantly correlated with sperm kinetics and DFI(both P<0.05),while no significant correlation was found with sperm morphological parameters(all P>0.05).The box plots and histograms of men’s age,abstinence time,and semen quality show that most semen quality parameters differ significantly between the 2 days and 7 days abstinence groups and other groups at different ages.Except for the sperm morphology parameters,sperm kinetic parameters and sperm DFI are linearly related to male age and abstinence time.展开更多
Treatment of acute and chronic wounds is one of the primary challenges faced by doctors.Bioderived materials have significant potential clinical value in tissue injury treatment and defect reconstruction.Various strat...Treatment of acute and chronic wounds is one of the primary challenges faced by doctors.Bioderived materials have significant potential clinical value in tissue injury treatment and defect reconstruction.Various strategies,including drug loading,addition of metallic element(s),crosslinking and combining two or more distinct types of materials with complementary features,have been used to synthesize more suitable materials for wound healing.In this review,we describe the recent developments made in the processing of bioderived materials employed for cutaneous wound healing,including newly developed materials such as keratin and soy protein.The focus was on the key properties of the bioderived materials that have shown great promise in improving wound healing,restoration and reconstruction.With their good biocompatibility,nontoxic catabolites,microinflammation characteristics,as well as their ability to induce tissue regeneration and reparation,the bioderived materials have great potential for skin tissue repair.展开更多
基金This work was supported by funding from the Fujian Provincial Maternity and Children Hospital(No.YCXM19-29)the Fujian Natural Science Foundation(No.2019J01511 and No.2020Y0067)the Health Research Project of the Department of Finance(Fujian finance refers to[2019]No.827).
文摘This study analyzed the effects of male age and abstinence time on semen quality and explored the best abstinence time for Chinese males among different age groups.Semen parameters,including sperm kinetics,morphology,and DNA fragmentation index(DFI),were reviewed from 2952 men.Samples were divided into six age groups(≤25 years,26–30 years,31–35 years,36–40 years,41–45 years,and>45 years)and were divided into six groups according to different abstinence time(2 days,3 days,4 days,5 days,6 days,and 7 days).The differences in semen quality between the groups were compared,and the effect of age and abstinence time on semen quality was analyzed.Significant differences were observed in semen volume,progressive motility(PR),and DFI among the age groups(all P<0.05),and no significant differences were observed in sperm morphological parameters(all P>0.05).There were significant differences in semen volume,PR,and DFI among different abstinence time groups(all P<0.05)and no significant differences in sperm morphological parameters(all P>0.05).Pearson analysis showed that male age and abstinence time were both significantly correlated with sperm kinetics and DFI(both P<0.05),while no significant correlation was found with sperm morphological parameters(all P>0.05).The box plots and histograms of men’s age,abstinence time,and semen quality show that most semen quality parameters differ significantly between the 2 days and 7 days abstinence groups and other groups at different ages.Except for the sperm morphology parameters,sperm kinetic parameters and sperm DFI are linearly related to male age and abstinence time.
基金This work was supported by the National Key Research and Development Program of China(grant number 2017YFC1104702)the National Natural Science Foundation of China(grant numbers 31600792,31771065).
文摘Treatment of acute and chronic wounds is one of the primary challenges faced by doctors.Bioderived materials have significant potential clinical value in tissue injury treatment and defect reconstruction.Various strategies,including drug loading,addition of metallic element(s),crosslinking and combining two or more distinct types of materials with complementary features,have been used to synthesize more suitable materials for wound healing.In this review,we describe the recent developments made in the processing of bioderived materials employed for cutaneous wound healing,including newly developed materials such as keratin and soy protein.The focus was on the key properties of the bioderived materials that have shown great promise in improving wound healing,restoration and reconstruction.With their good biocompatibility,nontoxic catabolites,microinflammation characteristics,as well as their ability to induce tissue regeneration and reparation,the bioderived materials have great potential for skin tissue repair.
