目的构建一种基于深度学习的小肝癌磁共振影像超分辨重建模型,通过联合优化高频细节与解剖合理性,提升小肝癌病灶的影像细节可视性,提升小肝癌扩散加权成像(DWI)检查的图像质量及临床应用价值。方法回顾性分析2022年12月~2024年6月我院...目的构建一种基于深度学习的小肝癌磁共振影像超分辨重建模型,通过联合优化高频细节与解剖合理性,提升小肝癌病灶的影像细节可视性,提升小肝癌扩散加权成像(DWI)检查的图像质量及临床应用价值。方法回顾性分析2022年12月~2024年6月我院300例小肝癌患者的3 mm DWI数据。采用GE Discovery7503.0 T扫描仪采集图像,按8∶2比例随机分为训练集(n=240)和测试集(n=60)。构建双分支超分辨模型:内容分支通过级联梯度Transformer块提取全局特征,梯度分支通过梯度Transformer块增强结构信息;创新性引入:(1)交叉局部增强自注意力模块,以优化块内像素特征与全局上下文信息的交互;(2)通道-空间联合注意力层,通过动态权重分配增强关键解剖结构的可视性。由3名高年资放射科医师采用5分制Likert量表对原始弥散加权成像(ORDWI)和超分辨弥散加权成像(SRDWI)进行盲法评分,同时计算峰值信噪比、结构相似度等客观指标。结果SRDWI的主观评分优于ORDWI:肝结节信号特异性(3.41±0.53 vs 2.47±0.50)、正常肝实质均匀性(3.29±0.47 vs 2.78±0.42)、伪影干扰程度(2.56±0.52 vs 2.47±0.48)及整体图像质量(3.15±0.49 vs 2.67±0.48)上的主观评分优于ORDWI(P<0.001)。图像噪声水平(3.98±0.61 vs 2.87±0.46)超分后略有增加(P<0.05),但仍在临床可接受范围内,不影响关键特征的判读。客观指标显示SRDWI的峰值信噪比(34.65489 dB)和结构相似度(0.90365)均表现优异。结论该深度学习模型可显著提升3 mm-DWI图像质量,使薄层DWI的诊断效能接近常规厚层扫描水平,为小肝癌精准诊断提供技术支持。展开更多
The Karatau fault is one of the important strike-slip faults in central Asia,and the South Turgay Basin is located towards its northern end.Detailed seismic interpretation indicated that the strikeslip tectonism of th...The Karatau fault is one of the important strike-slip faults in central Asia,and the South Turgay Basin is located towards its northern end.Detailed seismic interpretation indicated that the strikeslip tectonism of the Karatau fault weakened gradually from west to east in the South Turgay Basin.Typical flower structures developed on the section,and strike-slip faults showed an echelon pattern on planar view.The Karatau strike-slip fault affected the South Turgay Basin in two periods：（1） The South Turgay strike-slip pull-apart rift basin formed as a result of regional extensive stress in the Early-Middle Jurassic,characterized by the juxtaposition of horsts and grabens.The formation of horsts provided favorable reservoir spaces for later hydrocarbon accumulation,and different filling stages of grabens controlled different reservoir-forming factors in grabens.（2） Two stages of tectonic inversion occurred in the Late Jurassic and Late Cretaceous and played a crucial role in the final shape of the structure in the South Turgay Basin.The oil and gas migrated to form reservoirs and mainly concentrated in the horsts,graben slopes and in both sides of the strike-slip fault zone.In the case of the degree of accumulation of petroleum,the factor explaining why horsts are better than grabens is the strike-slip pull-apart of the South Turgay Basin,and the structure inversion of the South Turgay Basin explains why the west graben is better than the east one.Overall,the Karatau strike-slip fault played a very important role in the formation of the South Turgay Basin and its hydrocarbon accumulations.展开更多
文摘目的构建一种基于深度学习的小肝癌磁共振影像超分辨重建模型,通过联合优化高频细节与解剖合理性,提升小肝癌病灶的影像细节可视性,提升小肝癌扩散加权成像(DWI)检查的图像质量及临床应用价值。方法回顾性分析2022年12月~2024年6月我院300例小肝癌患者的3 mm DWI数据。采用GE Discovery7503.0 T扫描仪采集图像,按8∶2比例随机分为训练集(n=240)和测试集(n=60)。构建双分支超分辨模型:内容分支通过级联梯度Transformer块提取全局特征,梯度分支通过梯度Transformer块增强结构信息;创新性引入:(1)交叉局部增强自注意力模块,以优化块内像素特征与全局上下文信息的交互;(2)通道-空间联合注意力层,通过动态权重分配增强关键解剖结构的可视性。由3名高年资放射科医师采用5分制Likert量表对原始弥散加权成像(ORDWI)和超分辨弥散加权成像(SRDWI)进行盲法评分,同时计算峰值信噪比、结构相似度等客观指标。结果SRDWI的主观评分优于ORDWI:肝结节信号特异性(3.41±0.53 vs 2.47±0.50)、正常肝实质均匀性(3.29±0.47 vs 2.78±0.42)、伪影干扰程度(2.56±0.52 vs 2.47±0.48)及整体图像质量(3.15±0.49 vs 2.67±0.48)上的主观评分优于ORDWI(P<0.001)。图像噪声水平(3.98±0.61 vs 2.87±0.46)超分后略有增加(P<0.05),但仍在临床可接受范围内,不影响关键特征的判读。客观指标显示SRDWI的峰值信噪比(34.65489 dB)和结构相似度(0.90365)均表现优异。结论该深度学习模型可显著提升3 mm-DWI图像质量,使薄层DWI的诊断效能接近常规厚层扫描水平,为小肝癌精准诊断提供技术支持。
基金supported by the Major National Science and Technology Projects of China (No. 2008ZX05029-002)CNPC Research Topics of China (No.07B60101)
文摘The Karatau fault is one of the important strike-slip faults in central Asia,and the South Turgay Basin is located towards its northern end.Detailed seismic interpretation indicated that the strikeslip tectonism of the Karatau fault weakened gradually from west to east in the South Turgay Basin.Typical flower structures developed on the section,and strike-slip faults showed an echelon pattern on planar view.The Karatau strike-slip fault affected the South Turgay Basin in two periods：（1） The South Turgay strike-slip pull-apart rift basin formed as a result of regional extensive stress in the Early-Middle Jurassic,characterized by the juxtaposition of horsts and grabens.The formation of horsts provided favorable reservoir spaces for later hydrocarbon accumulation,and different filling stages of grabens controlled different reservoir-forming factors in grabens.（2） Two stages of tectonic inversion occurred in the Late Jurassic and Late Cretaceous and played a crucial role in the final shape of the structure in the South Turgay Basin.The oil and gas migrated to form reservoirs and mainly concentrated in the horsts,graben slopes and in both sides of the strike-slip fault zone.In the case of the degree of accumulation of petroleum,the factor explaining why horsts are better than grabens is the strike-slip pull-apart of the South Turgay Basin,and the structure inversion of the South Turgay Basin explains why the west graben is better than the east one.Overall,the Karatau strike-slip fault played a very important role in the formation of the South Turgay Basin and its hydrocarbon accumulations.
