Atropisomeric phosphines are crucial for asymmetric catalysis but remain synthetically challenging.Herein,an N-heterocyclic carbene(NHC)catalyzed esterification reaction of dialdehydes with arylboronic acids was devel...Atropisomeric phosphines are crucial for asymmetric catalysis but remain synthetically challenging.Herein,an N-heterocyclic carbene(NHC)catalyzed esterification reaction of dialdehydes with arylboronic acids was developed,successfully constructing the framework of axially chiral phosphorus compounds.Mechanistic studies have revealed that the reaction initially undergoes a desymmetrization process,followed by a kinetic resolution pathway,affording a series of axially chiral phosphorus compounds with high enantioselectivity(up to 92%ee).展开更多
莺尾观赏价值极高,且是制作香水和中药的重要原材料。莺尾重型花叶病毒(Iris severe mosaic virus,ISMV)属马铃薯Y病毒属Potyvirus,是导致莺尾花叶病的主要病原,广泛分布于我国各莺尾种植区。近年来随着园艺植物贸易的频繁化与国际化,I...莺尾观赏价值极高,且是制作香水和中药的重要原材料。莺尾重型花叶病毒(Iris severe mosaic virus,ISMV)属马铃薯Y病毒属Potyvirus,是导致莺尾花叶病的主要病原,广泛分布于我国各莺尾种植区。近年来随着园艺植物贸易的频繁化与国际化,ISMV可随莺尾种苗在全球各国间调运,存在广泛扩散的潜在威胁'本研究拟通过扩增ISMV泰安分离物全基因组序列,并对该序列特征进行分析,以期为了解我国ISMV的遗传进化并对该病害的防控提供依据。展开更多
基金Project supported by the Natural Science Foundation of Henan Province(Nos.232300421234,252300421726)the Leading Talents in Scientific and Technological Innovation in Shangqiu(No.SQRC202212004)the Program of Ecological Environmental Protection in the Area of Old Course of Yellow River of Shangqiu Normal University。
文摘Atropisomeric phosphines are crucial for asymmetric catalysis but remain synthetically challenging.Herein,an N-heterocyclic carbene(NHC)catalyzed esterification reaction of dialdehydes with arylboronic acids was developed,successfully constructing the framework of axially chiral phosphorus compounds.Mechanistic studies have revealed that the reaction initially undergoes a desymmetrization process,followed by a kinetic resolution pathway,affording a series of axially chiral phosphorus compounds with high enantioselectivity(up to 92%ee).
文摘莺尾观赏价值极高,且是制作香水和中药的重要原材料。莺尾重型花叶病毒(Iris severe mosaic virus,ISMV)属马铃薯Y病毒属Potyvirus,是导致莺尾花叶病的主要病原,广泛分布于我国各莺尾种植区。近年来随着园艺植物贸易的频繁化与国际化,ISMV可随莺尾种苗在全球各国间调运,存在广泛扩散的潜在威胁'本研究拟通过扩增ISMV泰安分离物全基因组序列,并对该序列特征进行分析,以期为了解我国ISMV的遗传进化并对该病害的防控提供依据。
