In this paper,the discrete element method(DEM)is used to study the microstructure of expansive soils.The results of the numerical calculations are in agreement with the stress-strain triaxial test curve that is obtain...In this paper,the discrete element method(DEM)is used to study the microstructure of expansive soils.The results of the numerical calculations are in agreement with the stress-strain triaxial test curve that is obtained for a representative expansive soil.Biaxial compression tests are conducted for different confining pressures(50 kpa,100 kpa,and 150 kpa).Attention is paid to the following aspects:deviatoric stress,boundary energy,friction energy,bond energy,strain energy,kinetic energy,and the contact force between grains when the test specimen is strained and to the effect of the different confining pressures on the internal crack expansion.The results of this research show that the cross-section of the specimen is destroyed along the middle part of the specimen itself.When the confining pressure is higher,the impulse is stronger,and this leads to more effective destruction.展开更多
Dion-Jacobson (DJ) phase hybrid perovskites have been proven to improve the photovoltaic performance of the devices due to its unique structure.At present,some DJ hybrid perovskites have been reported and used for pho...Dion-Jacobson (DJ) phase hybrid perovskites have been proven to improve the photovoltaic performance of the devices due to its unique structure.At present,some DJ hybrid perovskites have been reported and used for photodetection filed,but most of them are based on lead-bromide systems,which is not conducive to construct broadband photodetection devices due to the limitation of intrinsic absorption.Herein,we constructed a bilayered DJ hybrid perovskite (3AMPY)(EA)Pb_(2)I_(7)(3AMPY^(2+)is 3-(aminomethyl)pyridinium,EA^(+)is ethylammonium) using an aromatic spacer,which exhibit large current on/off ratios of 10~4under 520 and 637 nm illumination.In particular,the single crystal device based on (3AMPY)(EA)Pb_(2)I_(7)shows a distinguished detectivity of 7.4×10^(12)Jones and a high responsivity of 0.89A/W under 637 nm illumination.Such finding not only enriches the quantities of DJ hybrid perovskites,but also provides useful assistance for constructing high-performance optoelectronic device in the future.展开更多
BACKGROUND The degree of obstruction plays an important role in decision-making for obstructive colorectal cancer(OCRC).The existing assessment still relies on the colorectal obstruction scoring system(CROSS)which is ...BACKGROUND The degree of obstruction plays an important role in decision-making for obstructive colorectal cancer(OCRC).The existing assessment still relies on the colorectal obstruction scoring system(CROSS)which is based on a comprehensive analysis of patients’complaints and eating conditions.The data collection relies on subjective descriptions and lacks objective parameters.Therefore,a scoring system for the evaluation of computed tomography-based obstructive degree(CTOD)is urgently required for OCRC.AIM To explore the relationship between CTOD and CROSS and to determine whether CTOD could affect the short-term and long-term prognosis.METHODS Of 173 patients were enrolled.CTOD was obtained using k-means,the ratio of proximal to distal obstruction,and the proportion of nonparenchymal areas at the site of obstruction.CTOD was integrated with the CROSS to analyze the effect of emergency intervention on complications.Short-term and long-term outcomes were compared between the groups.RESULTS CTOD severe obstruction(CTOD grade 3)was an independent risk factor[odds ratio(OR)=3.390,95%confidence interval(CI):1.340-8.570,P=0.010]via multivariate analysis of short-term outcomes,while CROSS grade was not.In the CTOD-CROSS grade system,for the non-severe obstructive(CTOD 1-2 to CROSS 1-4)group,the complication rate of emergency interventions was significantly higher than that of non-emergency interventions(71.4%vs 41.8%,P=0.040).The postoperative pneumonia rate was higher in the emergency intervention group than in the non-severe obstructive group(35.7%vs 8.9%,P=0.020).However,CTOD grade was not an independent risk factor of overall survival and progression-free survival.CONCLUSION CTOD was useful in preoperative decision-making to avoid unnecessary emergency interventions and complications.展开更多
目的:探析阿替普酶(Alteplase,rt-PA)静脉溶栓治疗急性缺血性脑卒中(AIS)的临床效果及对凝血功能的影响。方法:回顾性分析2021年1月—2022年10月在龙岩市第二医院就诊的AIS患者中选取154例,以治疗方法分为对照组和观察组,对照组77例行...目的:探析阿替普酶(Alteplase,rt-PA)静脉溶栓治疗急性缺血性脑卒中(AIS)的临床效果及对凝血功能的影响。方法:回顾性分析2021年1月—2022年10月在龙岩市第二医院就诊的AIS患者中选取154例,以治疗方法分为对照组和观察组,对照组77例行常规治疗,观察组77例行rt-PA静脉溶栓。比较两组治疗指标。结果:观察组治疗总有效率(97.40%)较对照组(81.82%)高(P<0.05)。治疗后,观察组美国国立卫生研究院卒中量表(national institute health stroke scale,NIHSS)评分(13.02±1.32)分较对照组(14.57±1.43)分低;Barthel指数(BI)评分为(82.59±4.16)分较对照组(71.66±5.06)分高;血液流变学指标较对照组均降低;凝血功能血管性血友病因子(vWF)(0.99±0.09)g/L、凝血因子Ⅷ(FⅧ)(1.15±0.14)U/L较对照组vWF(1.70±0.15)g/L、FⅧ(1.97±0.24)U/L均更优;预后方面,死亡(0)、病情恶化(2.60%)较对照组死亡(14.29%)、病情恶化(16.88%)均更优(P<0.05)。结论:AIS治疗时选择rt-PA静脉溶栓取得的效果较为显著,神经功能缺损改善,生活能力提高,血液流变学、凝血功能改善,预后良好。展开更多
基金financially supported by the National Science Foundation of China(41877251)the science and technology innovation fund project of Xinxiang University(15ZA06).
文摘In this paper,the discrete element method(DEM)is used to study the microstructure of expansive soils.The results of the numerical calculations are in agreement with the stress-strain triaxial test curve that is obtained for a representative expansive soil.Biaxial compression tests are conducted for different confining pressures(50 kpa,100 kpa,and 150 kpa).Attention is paid to the following aspects:deviatoric stress,boundary energy,friction energy,bond energy,strain energy,kinetic energy,and the contact force between grains when the test specimen is strained and to the effect of the different confining pressures on the internal crack expansion.The results of this research show that the cross-section of the specimen is destroyed along the middle part of the specimen itself.When the confining pressure is higher,the impulse is stronger,and this leads to more effective destruction.
基金financially supported by the National Natural Science Foundation of China(Nos.22005183 and 22275117)the Program of State Key Laboratory of Quantum Optics and Quantum Optics Devices(No.KF202204)。
文摘Dion-Jacobson (DJ) phase hybrid perovskites have been proven to improve the photovoltaic performance of the devices due to its unique structure.At present,some DJ hybrid perovskites have been reported and used for photodetection filed,but most of them are based on lead-bromide systems,which is not conducive to construct broadband photodetection devices due to the limitation of intrinsic absorption.Herein,we constructed a bilayered DJ hybrid perovskite (3AMPY)(EA)Pb_(2)I_(7)(3AMPY^(2+)is 3-(aminomethyl)pyridinium,EA^(+)is ethylammonium) using an aromatic spacer,which exhibit large current on/off ratios of 10~4under 520 and 637 nm illumination.In particular,the single crystal device based on (3AMPY)(EA)Pb_(2)I_(7)shows a distinguished detectivity of 7.4×10^(12)Jones and a high responsivity of 0.89A/W under 637 nm illumination.Such finding not only enriches the quantities of DJ hybrid perovskites,but also provides useful assistance for constructing high-performance optoelectronic device in the future.
基金the Youth Foundation of Fujian Provincial Health Commission,No.2021QNA014the Construction Project of Fujian Province Minimally Invasive Medical Center,No.[2021]76.
文摘BACKGROUND The degree of obstruction plays an important role in decision-making for obstructive colorectal cancer(OCRC).The existing assessment still relies on the colorectal obstruction scoring system(CROSS)which is based on a comprehensive analysis of patients’complaints and eating conditions.The data collection relies on subjective descriptions and lacks objective parameters.Therefore,a scoring system for the evaluation of computed tomography-based obstructive degree(CTOD)is urgently required for OCRC.AIM To explore the relationship between CTOD and CROSS and to determine whether CTOD could affect the short-term and long-term prognosis.METHODS Of 173 patients were enrolled.CTOD was obtained using k-means,the ratio of proximal to distal obstruction,and the proportion of nonparenchymal areas at the site of obstruction.CTOD was integrated with the CROSS to analyze the effect of emergency intervention on complications.Short-term and long-term outcomes were compared between the groups.RESULTS CTOD severe obstruction(CTOD grade 3)was an independent risk factor[odds ratio(OR)=3.390,95%confidence interval(CI):1.340-8.570,P=0.010]via multivariate analysis of short-term outcomes,while CROSS grade was not.In the CTOD-CROSS grade system,for the non-severe obstructive(CTOD 1-2 to CROSS 1-4)group,the complication rate of emergency interventions was significantly higher than that of non-emergency interventions(71.4%vs 41.8%,P=0.040).The postoperative pneumonia rate was higher in the emergency intervention group than in the non-severe obstructive group(35.7%vs 8.9%,P=0.020).However,CTOD grade was not an independent risk factor of overall survival and progression-free survival.CONCLUSION CTOD was useful in preoperative decision-making to avoid unnecessary emergency interventions and complications.
文摘目的:探析阿替普酶(Alteplase,rt-PA)静脉溶栓治疗急性缺血性脑卒中(AIS)的临床效果及对凝血功能的影响。方法:回顾性分析2021年1月—2022年10月在龙岩市第二医院就诊的AIS患者中选取154例,以治疗方法分为对照组和观察组,对照组77例行常规治疗,观察组77例行rt-PA静脉溶栓。比较两组治疗指标。结果:观察组治疗总有效率(97.40%)较对照组(81.82%)高(P<0.05)。治疗后,观察组美国国立卫生研究院卒中量表(national institute health stroke scale,NIHSS)评分(13.02±1.32)分较对照组(14.57±1.43)分低;Barthel指数(BI)评分为(82.59±4.16)分较对照组(71.66±5.06)分高;血液流变学指标较对照组均降低;凝血功能血管性血友病因子(vWF)(0.99±0.09)g/L、凝血因子Ⅷ(FⅧ)(1.15±0.14)U/L较对照组vWF(1.70±0.15)g/L、FⅧ(1.97±0.24)U/L均更优;预后方面,死亡(0)、病情恶化(2.60%)较对照组死亡(14.29%)、病情恶化(16.88%)均更优(P<0.05)。结论:AIS治疗时选择rt-PA静脉溶栓取得的效果较为显著,神经功能缺损改善,生活能力提高,血液流变学、凝血功能改善,预后良好。
