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A special core-shell material(Mxene@Ag@Phytate)to improve EVA composite fire safety,radiation cross-linking effect,and electromagnetic shielding 被引量:2
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作者 Si-Yi Xu Dan-Yi Li +4 位作者 Wen-Rui Wang lin lin Ying Sun Ji-Hao Li lin-Fan Li 《Nuclear Science and Techniques》 2025年第2期27-39,共13页
High-performance MXene-based polymer nanocomposites are well-suited for various industrial applications owing to their excellent mechanical,thermal,and other properties.However,the fabrication of flame-retardant polym... High-performance MXene-based polymer nanocomposites are well-suited for various industrial applications owing to their excellent mechanical,thermal,and other properties.However,the fabrication of flame-retardant polymer/MXene nanocom-posites remains challenging owing to the limited flame-retardant properties of MXene itself.This study prepared a novel MXene@Ag@PA hybrid material via radiation modification and complexation reaction.This material was used to further enhance the key properties of ethylene-vinyl acetate(EVA),such as its mechanical properties,thermal conductivity,flame retardancy,and electromagnetic shielding.The addition of two parts of this hybrid material increased the thermal conduc-tivity of EVA by 44.2%and reduced its peak exothermic rate during combustion by 30.1%compared with pure EVA.The material also significantly reduced smoke production and increased the residue content.In the X-band,the electromagnetic shielding effectiveness of the EVA composites reached 20 dB.Moreover,the MXene@Ag@PA hybrid material could be used to further enhance the mechanical properties of EVA composites under electron-beam irradiation.Thus,this study contributes to the development of MXene-based EVA advanced materials that are fire-safe,have high strength,and exhibit good electromagnetic shielding performance for various applications. 展开更多
关键词 MXene@Ag@PA Ethylene-vinyl acetate(EVA) Flame retardancy Electromagnetic shielding performance
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YAP Signaling in Glia:Pivotal Roles in Neurological Development,Regeneration and Diseases 被引量:1
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作者 lin lin Yinfeng Yuan +1 位作者 Zhihui Huang Yongjie Wang 《Neuroscience Bulletin》 2025年第3期501-519,共19页
Yes-associated protein (YAP), the key transcriptional co-factor and downstream effector of the Hippo pathway, has emerged as one of the primary regulators of neural as well as glial cells. It has been detected in vari... Yes-associated protein (YAP), the key transcriptional co-factor and downstream effector of the Hippo pathway, has emerged as one of the primary regulators of neural as well as glial cells. It has been detected in various glial cell types, including Schwann cells and olfactory ensheathing cells in the peripheral nervous system, as well as radial glial cells, ependymal cells, Bergmann glia, retinal Müller cells, astrocytes, oligodendrocytes, and microglia in the central nervous system. With the development of neuroscience, understanding the functions of YAP in the physiological or pathological processes of glia is advancing. In this review, we aim to summarize the roles and underlying mechanisms of YAP in glia and glia-related neurological diseases in an integrated perspective. 展开更多
关键词 YAP Hippo pathway NEUROGLIA Nervous system Nervous system diseases
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Clinical analysis of colistin sulfate in the treatment of pneumonia caused by carbapenem-resistant Gram-negative bacteria 被引量:3
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作者 Hai-Chang Xu Yan Cui +6 位作者 Xue-Ying Wang Hai-Bo Wu Wei Li Dan Wang Na lin lin lin Ying-Hui Zhang 《World Journal of Clinical Cases》 SCIE 2024年第13期2173-2181,共9页
BACKGROUND Multidrug-resistant Gram-negative bacteria,exacerbated by excessive use of antimicrobials and immunosuppressants,are a major health threat.AIM To study the clinical efficacy and safety of colistin sulfate i... BACKGROUND Multidrug-resistant Gram-negative bacteria,exacerbated by excessive use of antimicrobials and immunosuppressants,are a major health threat.AIM To study the clinical efficacy and safety of colistin sulfate in the treatment of carbapenem-resistant Gram-negative bacilli-induced pneumonia,and to provide theoretical reference for clinical diagnosis and treatment.METHODS This retrospective analysis involved 54 patients with Gram-negative bacilli pneumonia admitted to intensive care unit of The General Hospital of the Northern Theater Command of the People's Liberation Army of China from August 2020 to June 2022.After bacteriological culture,the patients'airway secretions were collected to confirm the presence of Gram-negative bacilli.The patients were divided into the experimental and control groups according to the medication used.The research group consisted of 28 patients who received polymyxin sulfate combined with other drugs through intravenous,nebulization,or intravenous combined with nebulization,with a daily dosage of 1.5–3.0 million units.The control group consisted of 26 patients who received standard dosages of other antibiotics(including sulbactam sodium for injection,cefoperazone sodium sulbactam for injection,tigecycline,meropenem,or vaborbactam).RESULTS Of the 28 patients included in the research group,26 patients showed improvement,treatment was ineffective for two patients,and one patient died,with the treatment efficacy rate of 92.82%.Of the 26 patients in the control group,18 patients improved,treatment was ineffective for eight patients,and two patients died,with the treatment efficacy rate of 54.9%;significant difference was observed between the two groups(P<0.05).The levels of white blood cell(WBC),procalcitonin(PCT),and C-reactive protein(CRP)in both groups were significantly lower after treatment than before treatment(P<0.05),and the levels of WBC,PCT,and CRP in the research group were significantly lower than those in the control group(P<0.05).Compared with before treatment,there were no significant changes in aspartate aminotransferase,creatinine,and glomerular filtration rate in both groups,while total bilirubin and alanine aminotransferase decreased after treatment(P<0.05)with no difference between the groups.In patients with good clinical outcomes,the sequential organ failure assessment(SOFA)score was low when treated with inhaled polymyxin sulfate,and specific antibiotic treatment did not improve the outcome.Sepsis and septic shock as well as a low SOFA score were independent factors associated with good clinical outcomes.CONCLUSION Polymyxin sulfate has a significant effect on the treatment of patients with multiple drug-resistant Gram-negative bacilli pneumonia and other infections in the lungs and is safe and reliable.Moreover,the administration route of low-dose intravenous injection combined with nebulization shows better therapeutic effects and lower adverse reactions,providing new ideas for clinical administration. 展开更多
关键词 Colistin sulfate Extensively drug-resistant PNEUMONIA Intravenous combined with nebulization Sepsis NEPHROTOXICITY NEUROTOXICITY
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mok E基因过表达对红曲霉Monacolin K产量、菌丝及孢子形态的影响 被引量:13
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作者 林琳 王昌禄 +3 位作者 李贞景 陈勉华 武淑芬 任志远 《食品科学》 EI CAS CSCD 北大核心 2018年第8期45-49,共5页
红曲霉中mok E基因是红曲霉次级代谢产物Monacolin K生物合成的一个相关基因,mok E基因表达量与Monacolin K产量呈正相关。以mok E基因为目的基因,构建红曲霉mok E基因过表达工程菌株,通过逆转录实时荧光定量聚合酶链式反应(reverse tra... 红曲霉中mok E基因是红曲霉次级代谢产物Monacolin K生物合成的一个相关基因,mok E基因表达量与Monacolin K产量呈正相关。以mok E基因为目的基因,构建红曲霉mok E基因过表达工程菌株,通过逆转录实时荧光定量聚合酶链式反应(reverse transcription-quantitative real-time polymerase chain reaction,RT-q PCR)确定mok E基因过表达转化子,对转化子Monacolin K产量进行测定,同时利用扫描电镜,对野生型红曲霉M1及转化子菌丝、孢子进行观察。结果表明:以潮霉素抗性基因为筛选标记,成功得到240个转化子,对其中9个转化子进行mok E基因表达量测定,有3株转化子mok E基因表达量增加,分别为T2、T8、T9转化子,确定其为mok E基因过表达转化子;T2、T8、T9转化子内酯型Monacolin K产量分别为2 159.7、4 177.6、3 365.7μg/g,与野生型红曲霉Monacolin K产量(1 447.8μg/g)相比,分别提高了49.2%、188.5%及132.5%。扫描电镜结果显示,mok E基因过表达,对红曲霉的菌丝体、孢子形态及生殖方式均有影响。 展开更多
关键词 红曲霉 基因过表达 MONACOLINK 逆转录实时荧光定量聚合酶链式反应 扫描电镜 孢子
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PCOS患者和肽素、Ghrelin、DHEA-S水平及与胰岛素抵抗的相关性研究 被引量:10
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作者 赵智瑞 何国丽 +4 位作者 林琳 王智文 胡悦 曹宏伟 张爽 《生殖医学杂志》 CAS 2022年第8期1067-1072,共6页
目的探究和肽素、生长激素释放肽(Ghrelin)、硫酸脱氢表雄酮(DHEA-S)在多囊卵巢综合征(PCOS)中的水平及与胰岛素抵抗的相关性。方法选取2019年4月至2021年4月在秦皇岛市第一医院生殖医学科就诊治疗的PCOS患者130例作为研究对象(PCOS组)... 目的探究和肽素、生长激素释放肽(Ghrelin)、硫酸脱氢表雄酮(DHEA-S)在多囊卵巢综合征(PCOS)中的水平及与胰岛素抵抗的相关性。方法选取2019年4月至2021年4月在秦皇岛市第一医院生殖医学科就诊治疗的PCOS患者130例作为研究对象(PCOS组),选择同期在该院接受体检的健康女性100例作为健康对照组。又根据体质量指数(BMI)不同将PCOS组分为肥胖型组(50例)和非肥胖型组(80例)。PCOS患者接受炔雌醇环丙孕酮和二甲双胍治疗。采用血糖仪测量所有参与研究人员的空腹血糖水平,化学发光法测量DHEA-S水平、酶联免疫吸附法检测和肽素和Ghrelin水平。比较PCOS组、健康对照组的基线资料及PCOS肥胖型组、非肥胖型组治疗前后与健康对照组的和肽素、Ghrelin、DHEA-S及胰岛素抵抗指数(HOMA-IR)水平,并分析PCOS患者和肽素、Ghrelin、DHEA-S水平与HOMA-IR的相关性。结果PCOS组、健康对照组的年龄、BMI分布、血脂水平、血压水平等比较均无显著性差异(P>0.05)。PCOS肥胖型组患者治疗前和肽素、DHEA-S及HOMA-IR水平显著高于健康对照组和PCOS非肥胖型组(P<0.05),而Ghrelin水平显著低于健康对照组和PCOS非肥胖型组(P<0.05)。PCOS组患者治疗后和肽素、DHEA-S与HOMA-IR水平显著低于治疗前,而Ghrelin水平显著高于治疗前(P<0.05),且PCOS非肥胖型组患者各指标改善情况显著优于PCOS肥胖型组(P<0.05)。Pearson相关性分析显示,PCOS患者治疗前和肽素、DHEA-S水平与HOMA-IR呈显著正相关(P<0.05),Ghrelin水平与HOMA-IR呈显著负相关(P<0.05)。结论PCOS患者和肽素、DHEA-S高表达,Ghrelin低表达,且与HOMA-IR显著相关,可能为临床PCOS的诊断和治疗提供参考。 展开更多
关键词 多囊卵巢综合征 和肽素 生长激素释放肽 硫酸脱氢表雄酮 胰岛素抵抗 相关性
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Effect of endogenous insulin-like growth factor and stem cell factor on diabetic colonic dysmotility 被引量:18
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作者 Yun Wang Xin-Yu Xu +5 位作者 Yu-Rong Tang Wei-Wei Yang Yu-Feng Yuan Yue-Ji Ning Yin-Juan Yu lin lin 《World Journal of Gastroenterology》 SCIE CAS 2013年第21期3324-3331,共8页
AIM: To investigate whether the reduction of stem cell factor (SCF) is mediated by decreased endogenous insulin-like growth factor (IGF)-1 in diabetic rat colon smooth muscle. METHODS: Sixteen Sprague-Dawley rats were... AIM: To investigate whether the reduction of stem cell factor (SCF) is mediated by decreased endogenous insulin-like growth factor (IGF)-1 in diabetic rat colon smooth muscle. METHODS: Sixteen Sprague-Dawley rats were randomly divided into two groups: control group and streptozotocin-induced diabetic group. After 8 wk of streptozotocin administration, colonic motility function and contractility of circular muscle strips were measured. The expression of endogenous IGF-1 and SCF was tested in colonic tissues. Colonic smooth muscle cells were cultured from normal adult rats. IGF-1 siRNA transfection was used to investigate whether SCF expression was affected by endogenous IGF-1 expression in smooth muscle cells, and IGF-1 induced SCF expression effects were studied. The effect of high glucose on the expression of endogenous IGF-1 and SCF was also investigated. RESULTS: Diabetic rats showed prolonged colonic transit time (252 ± 16 min vs 168 ± 9 min, P < 0.01) and weakness of circular muscle contraction (0.81 ± 0.09 g vs 2.48 ± 0.23 g, P < 0.01) compared with the control group. Endogenous IGF-1 and SCF protein expression was significantly reduced in the diabetic colonic muscle tissues. IGF-1 and SCF mRNA expression also showed a paralleled reduction in diabetic rats. In the IGF-1 siRNA transfected smooth muscle cells, SCF mRNA and protein expression was significantly decreased. IGF-1 could induce SCF expression in a concentration and time-dependent manner, mainly through the extracellular-signal-regulated kinase 1/2 signal pathway. High glucose inhibited endogenous IGF-1 and SCF expression and the addition of IGF-1 to the medium reversed the SCF expression. CONCLUSION: Myopathy may resolve in colonic motility dysfunction in diabetic rats. Deficiency of endogenous IGF-1 in colonic smooth muscle cells leads to reduction of SCF expression. 展开更多
关键词 Diabetes GASTROINTESTINAL MOTILITY function INSULIN-LIKE growth factor-1 Stem CELL factor Smooth muscle CELL
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Serum Uric Acid is Associated with the Predicted Risk of Prevalent Cardiovascular Disease in a Community-dwelling Population without Diabetes 被引量:13
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作者 CHENG Di DU Rui +10 位作者 WU Xue Yan lin lin PENG Kui MA Li Na XU Yu XU Min CHEN Yu Hong BI Yu Fang WANG Wei Qing DAI Meng LU Jie Li 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2018年第2期106-114,共9页
Objective To examine the association between serum uric acid levels and cardiovascular disease risk among individuals without diabetes.Methods We investigated the association between serum uric acid levels and the ris... Objective To examine the association between serum uric acid levels and cardiovascular disease risk among individuals without diabetes.Methods We investigated the association between serum uric acid levels and the risk of prevalent cardiometabolic diseases, 10-year Framingham risk for coronary heart disease, and 10-year risk for atherosclerotic cardiovascular diseases (ASCVD) among 8,252 participants aged 〉 40 years without diabetes from Jiading district, Shanghai, China.Results Body mass index, waist circumference, blood glucose, glycated hemoglobin, blood pressure, and serum lipids increased progressively across the sex-specific quartiles of uric acid (all P trend 〈 0.05). Compared with individuals in the lowest quartile, those in the higher quartiles had a significantly higher prevalence of obesity, hypertension, and dyslipidemia (all P trend 〈 0.05). A fully adjusted logistic regression analysis revealed that individuals in the highest quartile had an increased risk of predicted cardiovascular disease compared with those in the lowest quartile of uric acid. The multivariate adjusted odds ratios (ORs) [95% confidence intervals (C/s)] for the highest quartiles for high Framingham risk were 3.00 (2.00-4.50) in men and 2.95 (1.08-8.43) in women. The multivariate adjusted ORs (95% C/s) for the highest quartile for high ASCVD risk were 1.93 [1.17-3.17) in men and 4.53 (2.57-7.98) in women.Conclusion Serum uric acid level is associated with an increased risk of prevalent obesity, hypertension, dystipidemia, 10-year Framingham risk for coronary heart disease, and lO-year risk for ASCVD among Chinese adults without diabetes. 展开更多
关键词 Uric acid Cardiovascular disease Framingham risk score Atherosclerotic cardiovasculardiseases
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白藜芦醇对实验性自身免疫性心肌炎大鼠心肌巨噬细胞极化及心肌炎性损伤的影响 被引量:4
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作者 林琳 樊刚 +3 位作者 李青 朱文静 薛嘉虹 魏瑾 《陕西医学杂志》 CAS 2025年第1期27-32,共6页
目的:探讨白藜芦醇(Res)对实验性自身免疫性心肌炎(EAM)大鼠心肌巨噬细胞极化及炎性损伤的影响。方法:建立EAM大鼠模型,分为对照组、EAM组、Resveratrol组,通过免疫荧光、HE染色观察心肌组织巨噬细胞浸润程度并对心肌病理损伤进行评分;... 目的:探讨白藜芦醇(Res)对实验性自身免疫性心肌炎(EAM)大鼠心肌巨噬细胞极化及炎性损伤的影响。方法:建立EAM大鼠模型,分为对照组、EAM组、Resveratrol组,通过免疫荧光、HE染色观察心肌组织巨噬细胞浸润程度并对心肌病理损伤进行评分;采用Realtime PCR检测巨噬细胞极化标记分子诱生型一氧化氮合酶(iNOS)、精氨酸酶1(Arg1)及炎症因子白细胞介素6(IL-6)、白细胞介素1β(IL-1β)、肿瘤坏死因子-α(TNF-α)的表达变化,Western blot检测NLRP3炎性小体蛋白组分的表达变化。结果:EAM组大鼠心肌组织可见大量巨噬细胞浸润,伴有明显的心肌纤维断裂、溶解;IL-6、IL-1β、TNF-α、iNOS mRNA表达均较Control组显著增加(分别为P<0.05,P<0.05,P<0.01,P<0.01),而Arg1表达较Control组显著减少(P<0.05);Resveratrol可减少EAM大鼠心肌组织巨噬细胞浸润数量及心肌病理损伤积分(均P<0.05),减少IL-6、IL-1β、TNF-α、iNOS mRNA的表达(均P<0.05),增加Arg1的表达(P<0.01)。同时,与Control组比较,EAM大鼠心肌组织NLRP3和Caspase-p10、pro-Caspase-1及IL-1β蛋白表达明显升高(均P<0.05),Resveratrol可显著减少人NOD样受体家组蛋白3(NLRP3)、Caspase-p10、pro-Caspase-1及IL-1β蛋白表达,差异具有统计学意义(均P<0.05)。结论:巨噬细胞浸润并向M1型极化参与EAM大鼠心肌炎性损伤;Res可能通过抑制M1型巨噬细胞向M2型极化、NLRP3炎症小体激活及相关炎性因子释放减轻EAM心肌损伤。 展开更多
关键词 巨噬细胞极化 炎症因子 白藜芦醇 实验性自身免疫性心肌炎 心肌损伤 人NOD样受体家组蛋白3炎症小体
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Investigation of scale efect for the computation of turbulent flow around a circular cylinder 被引量:2
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作者 lin lin Yan-Ying Wang 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2013年第5期641-648,共8页
In order to investigate the scale effect of turbulent flow around a circular cylinder, two similarity numbers (criteria) based on turbulent kinetic and dissipation rates associ- ated with the fluctuation characteris... In order to investigate the scale effect of turbulent flow around a circular cylinder, two similarity numbers (criteria) based on turbulent kinetic and dissipation rates associ- ated with the fluctuation characteristics of turbulence wake are deduced by analyzing the Reynolds averaged NavierStokes equations (RANS). The RNG k-s models and finite volume method are used to solve the governing equations and the second-order implicit time and upwind space discretization algorithms are used to discrete the governing equations. A numerical computation of flow parameters around a two-dimensional circular cylinder with Reynolds numbers ranging from 102 to l07 is accomplished and the result indicates that the fluctuation of turbulence flow along the center line in the wake of circular cylinder can never be changed with increasing Reynolds numbers when Re ≥ 3 × 10^6. This conclusion is useful for controlling the scale of numerical calculations and for applying model test data to engineering practice. 展开更多
关键词 Turbulent flow Flow around circular cylinder Scale effect Dynamic similarity
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Unusual tunability of multiferroicity in GdMn_(2)O_(5) by electric field poling far above multiferroic ordering point 被引量:1
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作者 Xiang Li Shuhan Zheng +9 位作者 Liman Tian Rui Shi Meifeng Liu Yunlong Xie Lun Yang Nian Zhao lin lin Zhibo Yan Xiuzhang Wang Junming Liu 《Chinese Physics B》 SCIE EI CAS CSCD 2019年第2期420-427,共8页
The multiferroicity in the RMn_(2)O_(5)family remains unclear,and less attention has been paid to its dependence on high-temperature(high-T)polarized configuration.Moreover,no consensus on the high-T space group symme... The multiferroicity in the RMn_(2)O_(5)family remains unclear,and less attention has been paid to its dependence on high-temperature(high-T)polarized configuration.Moreover,no consensus on the high-T space group symmetry has been reached so far.In view of this consideration,one may argue that the multiferroicity of RMn_(2)O_(5)in the low-T range depends on the poling sequence starting far above the multiferroic ordering temperature.In this work,we investigate in detail the variation of magnetically induced electric polarization in GdMn_(2)O_(5)and its dependence on electric field poling routine in the high-T range.It is revealed that the multiferroicity does exhibit qualitatively different behaviors if the high-T poling routine changes,indicating the close correlation with the possible high-T polarized state.These emergent phenomena may be qualitatively explained by the co-existence of two low-T polarization components,a scenario that was proposed earlier.One is the component associated with the Mn^(3+)–Mn^(4+)–Mn^(3+)exchange striction that seems to be tightly clamped by the high-T polarized state,and the other is the component associated with the Gd Mn^(3+)–Mn^(4+)–Mn^(3+)exchange striction that is free of the clamping.The present findings may offer a different scheme for the electric control of the multiferroicity in RMn_(2)O_(5). 展开更多
关键词 multiferroicity GdMn_(2)O_(5) high-T polarized state exchange striction
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Climate change impacts the distribution of Quercus section Cyclobalanopsis(Fagaceae),a keystone lineage in East Asian evergreen broadleaved forests 被引量:1
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作者 lin lin Xiao-Long Jiang +2 位作者 Kai-Qi Guo Amy Byrne Min Deng 《Plant Diversity》 SCIE CAS CSCD 2023年第5期552-568,共17页
East Asian evergreen broadleaved forests(EBFLs) harbor high species richness,but these ecosystems are severely impacted by global climate change and deforestation.Conserving and managing EBLFs requires understanding d... East Asian evergreen broadleaved forests(EBFLs) harbor high species richness,but these ecosystems are severely impacted by global climate change and deforestation.Conserving and managing EBLFs requires understanding dominant tree distribution dynamics.In this study,we used 29 species in Quercus section Cyclobalanopsis-a keystone lineage in East Asian EBLFs-as proxies to predict EBLF distribution dynamics using species distribution models(SDMs).We examined climatic niche overlap,similarity,and equivalency among seven biogeographical regions’ species using’ecospat’.We also estimated the effectiveness of protected areas in the predicted range to elucidate priority conservation regions.Our results showed that the climatic niches of most geographical groups differ.The western species under the Indian summer monsoon regime were mainly impacted by temperature factors,whereas precipitation impacted the eastern species under the East Asian summer monsoon regime.Our simulation predicted a northward range expansion of section Cyclobalanopsis between 2081 and 2100,except for the ranges of the three Himalayan species analyzed,which might shrink significantly.The greatest shift of highly suitable areas was predicted for the species in the South Pacific,with a centroid shift of over 300 km.Remarkably,only 7.56% of suitable habitat is currently inside protected areas,and the percentage is predicted to continue declining in the future.To better conserve Asian EBLFs,establishing nature reserves in their northern distribution ranges,and transplanting the populations with predicted decreasing numbers and degraded habitats to their future highly suitable areas,should be high-priority objectives. 展开更多
关键词 Species distribution model(SDM) East Asian tropics and subtropics Biodiversity conservation Distribution dynamics Global climate change
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The Ultraviolet Detection of Corona Discharge in Power Transmission Lines 被引量:1
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作者 Lan Chen lin lin +3 位作者 Mimi Tian Xingming Bian Liming Wang Zhicheng Guan 《Energy and Power Engineering》 2013年第4期1298-1302,共5页
Corona discharge is a common phenomenon in power transmission lines external insulation, and it may cause serious defect if without effective detection. The ultraviolet (UV) imagery technology has been widely used to ... Corona discharge is a common phenomenon in power transmission lines external insulation, and it may cause serious defect if without effective detection. The ultraviolet (UV) imagery technology has been widely used to detect the corona discharge in industry in recent years, but some influence factors’ functions are not definite. In this paper, the fracture aluminum strands which is common in power transmission lines were used as the electrode model while a SuperB ultraviolet imager were utilized to detect, the photon count rate was detected with different detect distance, electric field, aluminum strands length and UV gain were applied. Then the multivariate regression analysis (MRA) was taken to calculate the function between the photon count and the factors. 展开更多
关键词 CORONA DISCHARGE Transmission LINES DEFECT Detection UV IMAGER MULTIVARIATE Regression Analysis
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Online Parallel-Batch Machines Scheduling with a Single Server 被引量:1
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作者 FU Ru-yan lin lin 《Chinese Quarterly Journal of Mathematics》 2022年第4期403-411,共9页
We consider parallel-batch machines scheduling problem with a single server to minimize the maximum completion time.Jobs arrive over time.Every batch has to be loaded by the sever before being processed on machines.Th... We consider parallel-batch machines scheduling problem with a single server to minimize the maximum completion time.Jobs arrive over time.Every batch has to be loaded by the sever before being processed on machines.The loading(setup)operation of a batch occurs only when some machine is idle,and the server can perform only one setup operation every time.For some special case,we provide a best possible online algorithm with competitive ratio■.For general case,we give another online algorithm with competitive ratio 3. 展开更多
关键词 Parallel-batch machines SERVER Online algorithm Competitive ratio
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Effects of road dust on the growth characteristics of Sophora japonica L.seedlings 被引量:1
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作者 Le Bao Laiye Qu +1 位作者 Keming Ma lin lin 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2016年第8期147-155,共9页
Road dust is one of the most common pollutants and causes a series of negative effects on plant physiology. Dust's impacts on plants can be regarded as a combination of load,composition and grain size impacts on plan... Road dust is one of the most common pollutants and causes a series of negative effects on plant physiology. Dust's impacts on plants can be regarded as a combination of load,composition and grain size impacts on plants; however, there is a lack of integrated dust effect studies involving these three aspects. In our study, Sophora japonica seedlings were artificially dusted with road dust collected from the road surface of Beijing so that we could study the impacts of this dust on nitrogen/carbon allocation, biomass allocation and photosynthetic pigments from the three aspects of composition, load and grain size. The results showed that the growth characteristics of S. japonica seedlings were mostly influenced by dust composition and load. Leaf N, root–shoot ratio and chlorophyll a/b were significantly affected by dust composition and load; leaf C/N, shoot biomass, total chlorophyll and carotenoid were significantly affected by dust load; stem N and stem C/N were significantly affected by dust composition; while the dust grain size alone did not affect any of the growth characteristics. Road dust did influence the growth characteristics more extensively than loam. Therefore, a higher dust load could increase the differences between road dust and loam treatments. The elements in dust are well correlated to the shoot N, shoot C/N, and root–shoot ratio of S. japonica seedlings. This knowledge could benefit the management of urban green spaces. 展开更多
关键词 Dust composition Dust load Dust grain size Nitrogen Biomass
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数实融合对碳排放的影响及作用机制研究 被引量:2
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作者 张平淡 郝时雨 林琳 《求是学刊》 北大核心 2025年第1期88-99,共12页
数字技术、数字经济与实体经济的融合与发展是推进新型工业化和推动经济高质量发展的重要途径。基于2011—2019年中国268个地级市的面板数据的实证发现,数实融合有效推动了碳排放强度下降,也能有效抑制碳排放总量,发挥了显著的降碳效应... 数字技术、数字经济与实体经济的融合与发展是推进新型工业化和推动经济高质量发展的重要途径。基于2011—2019年中国268个地级市的面板数据的实证发现,数实融合有效推动了碳排放强度下降,也能有效抑制碳排放总量,发挥了显著的降碳效应。不过,这种效应存在基于工业化和数字化两个维度的异质性。进一步,从要素配置优化、技术创新两个角度揭示了数实融合发挥降碳效应的作用机制,可以观察到数实融合能够强化资本能源投入比、改善能源效率,还能带动研发投入,扩大专利产出,甚至还能促进绿色技术创新。拓展分析发现,政府对节能降碳的关注能有效放大数实融合的降碳效应。因此,应加快数字经济发展,促进数字技术、数字经济与实体经济的深度融合,协同推进经济高质量发展和生态环境高水平保护,助力“双碳”目标的实现。 展开更多
关键词 数实融合 “双碳”目标 数字经济 碳排放
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新质生产力形成中建设高标准数据要素市场的框架与路径研究 被引量:2
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作者 任保平 王昕 林琳 《西北工业大学学报(社会科学版)》 2025年第1期98-104,共7页
数据要素的市场化配置是数据资源利用效率最大化和价值实现的重要手段,是形成数据要素市场的重要支撑。数据要素市场化的形成机制包括数据要素的市场化配置机制、数据与其他生产要素相互组合中的市场化配置机制。高标准数据要素市场建... 数据要素的市场化配置是数据资源利用效率最大化和价值实现的重要手段,是形成数据要素市场的重要支撑。数据要素市场化的形成机制包括数据要素的市场化配置机制、数据与其他生产要素相互组合中的市场化配置机制。高标准数据要素市场建设的目标要求是提升数据要素供给质量、探索数据要素确权机制、搭建数据要素交易场所、强化数据要素交易监管。高标准数据要素市场建设的体系框架包括加快构建开放有序的供给体系、高效畅通的流通体系、数实融合的应用体系、安全导向的监管体系和创新高效的基础设施体系。高标准数据要素市场建设的路径是通过建立数据要素产权制度、培育数据要素交易流通生态、促进数据要素与实体经济深度融合、完善数据要素参与分配的制度安排,实现数据要素市场高标准化的战略目标。 展开更多
关键词 新质生产力 数据要素 高标准数据要素市场 体系框架
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多模态超声评价颈动脉斑块易损性与冠心病患者血清人可溶性配体、妊娠相关血浆蛋白A水平的相关性 被引量:1
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作者 黄志平 吴龙燕 +2 位作者 郭明英 林霖 丁小军 《中国当代医药》 2025年第1期71-75,共5页
目的探讨多模态超声评价颈动脉斑块易损性与冠心病患者血清人可溶性配体(sCD40L)、妊娠相关血浆蛋白A(PAPP-A)水平的相关性。方法选取2022年5月至2023年10月赣州市人民医院资料完整的60例冠心病患者作为研究对象,行颈动脉二维超声、超... 目的探讨多模态超声评价颈动脉斑块易损性与冠心病患者血清人可溶性配体(sCD40L)、妊娠相关血浆蛋白A(PAPP-A)水平的相关性。方法选取2022年5月至2023年10月赣州市人民医院资料完整的60例冠心病患者作为研究对象,行颈动脉二维超声、超微血流成像、超声造影多模态超声检查,综合评价斑块的易损性,根据斑块易损或稳定分为易损斑块组(29例)和非易损斑块组(31例),比较两组sCD40L、PAPP-A检测水平,分析研究斑块易损性与血清CD40L、PAPP-A的相关性。结果以目前颈动脉斑块解剖成像的金标准高分辨率磁共振确诊阳性、阴性例数分别为30、30例,多模态超声检查确诊阳性、阴性例数分别为29、31例(稳定性斑块患者30例,无斑块1例),多模态超声诊断准确度、灵敏度、特异度分别为95.00%、93.33%、96.67%;易损斑块组sCD40L、PAPP-A水平均高于非易损斑块组,差异有统计学意义(P<0.05);sCD40L、PAPP-A水平评判易损斑块有较高的准确性(AUC分别约0.728、0.948);颈动脉斑块易损性与sCD40L、PAPP-A水平呈正相关(P<0.05)。结论通过对冠心病患者进行颈动脉斑块多模态超声检查及实验室测定,证实颈动脉斑块易损性与sCD40L、PAPP-A存在密切相关,可预测冠心病患者冠状动脉斑块不稳定性,为临床诊断和治疗提供一定依据。 展开更多
关键词 多模态超声 颈动脉斑块易损性 冠心病 人可溶性配体 妊娠相关血浆蛋白A
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敲低lincRNA-COX2抑制单核细胞增生李斯特菌感染相关的巨噬细胞的凋亡和M1型极化
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作者 朱昱蓉 黄霜 +3 位作者 林琳 张峰源 姜旭淦 陈盛霞 《细胞与分子免疫学杂志》 CAS CSCD 北大核心 2023年第4期289-294,共6页
目的探讨长链基因间非编码RNA环加氧酶2(lincRNA-COX2)在单核细胞增生李斯特菌(Lm)感染所致RAW264.7细胞凋亡和细胞极化中的作用.方法体外培养RAW264.7细胞,分为未感染对照组、Lm感染组、小干扰RNA阴性对照(si-NC)组、si-NC联合Lm组、li... 目的探讨长链基因间非编码RNA环加氧酶2(lincRNA-COX2)在单核细胞增生李斯特菌(Lm)感染所致RAW264.7细胞凋亡和细胞极化中的作用.方法体外培养RAW264.7细胞,分为未感染对照组、Lm感染组、小干扰RNA阴性对照(si-NC)组、si-NC联合Lm组、lincRNA-COX2小干扰RNA(si-lincRNA-COX2)组、si-lincRNA-COX2联合Lm组.Lm感染复数(MOI)=10感染RAW264.7细胞,细菌感染6 h后收集细胞,倒置荧光显微镜和实时定量PCR检测siRNA转染抑制效率,Western blot法检测细胞中裂解型胱天蛋白酶3(c-caspase-3)、caspase-3、B细胞淋巴瘤因子2(Bcl2)、Bcl2相关X蛋白(BAX)、精氨酸酶1(Arg1)和诱导型一氧化氮合酶(iNOS)蛋白水平.结果Lm感染RAW264.7细胞后,c-caspase-3/caspase-3、BAX/Bcl2比值、iNOS蛋白水平较对照组显著上调,而Arg1水平较对照组下调.敲低lincRNA-COX2可抑制Lm感染引起的RAW264.7细胞中BAX/Bcl2、c-caspase-3/caspase-3及iNOS蛋白的升高,上调Lm感染后RAW264.7细胞中的Arg1蛋白.结论敲低lincRNA-COX2抑制Lm感染引起的RAW264.7细胞凋亡并抑制其向M1型极化. 展开更多
关键词 单核细胞增生李斯特菌 RAW264.7细胞 长链基因间非编码RNA环加氧酶2(lincRNA-COX2) 细胞凋亡 细胞极化
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从图书馆到学习中心:信息时代下的校园学习空间重构 被引量:1
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作者 苏平 林琳 罗霖熠 《华中建筑》 2025年第4期100-104,共5页
在信息时代下高校教学模式和学习空间的持续转变中,常规的图书馆正逐步被新型的学习中心所替代。作为以“学习者”为中心的校园综合体,学习中心在定位、功能和空间等不同方面对以“书籍”为中心的图书馆进行了升级和重构。结合对国内近... 在信息时代下高校教学模式和学习空间的持续转变中,常规的图书馆正逐步被新型的学习中心所替代。作为以“学习者”为中心的校园综合体,学习中心在定位、功能和空间等不同方面对以“书籍”为中心的图书馆进行了升级和重构。结合对国内近年来代表性案例的调研分析和国外案例的对比研究,分析高校学习中心作为非正式学习平台、容纳共享式学习场景的全新定位;探讨在建筑指标、功能配比及配套设施上的主要功能转变;进而在规划选址、建筑空间和室内布置等各个层级提出空间重构的设计策略。 展开更多
关键词 学习中心 非正式学习 共享学习空间 图书馆 重构
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Mechanical property statistical analysis of Gd50Al30Co20 amorphous wires for providing reference to design requirements of cooling system
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作者 Bin Luo Hong-xian Shen +3 位作者 lin lin Hai-chao Li Da-wei Xing Jian-fei Sun 《Journal of Iron and Steel Research International》 SCIE EI CAS CSCD 2018年第3期261-267,共7页
Gd50Al3oCo20 wires show excellent magnetocaloric properties and high heat exchange rate due to the microsize. The Weibull and lognormal methods were used for systematically analyzing its mechanical properties for matc... Gd50Al3oCo20 wires show excellent magnetocaloric properties and high heat exchange rate due to the microsize. The Weibull and lognormal methods were used for systematically analyzing its mechanical properties for matching the design requirements in cooling system. The wire exhibits average fracture strength of-969.5 MPa and typical fracture behavior of amorphous character. Moreover, the distributions of stresses for tensile strains at 10 values are estimated by probability plot and Chi-square goodness-of-fit test. The random stresses were best fitted by lognormal probability distribution for most studied cases; however, fracture strength was best fitted by Weibull probability distribution. It is interesting to note that the mean and standard deviation of the stresses (to reach specific tensile strain) increase as the tensile strain grows, accompanied by the coefficients of variation of stresses which decrease smoothly. It is concluded that the inhomogeneity of material does cause the scatter of stresses growth, and the scatter could be considerably large. 展开更多
关键词 Gd50Al30Co20 amorphous wire Tensile property Statistical analysis Variation coefficient
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