Ultrafine metal nanoparticles are crucial for various applications,such as energy storage,catalysis,electronics,and biomedicine,owing to their high surfaceto-volume ratio and unique electronic properties.However,conve...Ultrafine metal nanoparticles are crucial for various applications,such as energy storage,catalysis,electronics,and biomedicine,owing to their high surfaceto-volume ratio and unique electronic properties.However,conventional nanoparticle synthesis methods often face challenges like irregular shapes and agglomeration,leading to compromised functionality.To address these challenges,this paper introduces a novel,rapid,high-temperature thermal radiation heating for the ultrafast synthesis and dispersion of metal nanoparticles.Utilizing the heating properties of carbon materials,the direct Joule heating generated by them rises to 1800-2000 K within~200 ms,followed by cooling to room temperature at a rate of 2×10^(3)K s^(-1).展开更多
While silicon/carbon(Si/C)is considered one of the most promising anode materials for the next generation of high-energy lithium-ion batteries(LIBs),the industrialization of Si/C anodes is hampered by high-cost and lo...While silicon/carbon(Si/C)is considered one of the most promising anode materials for the next generation of high-energy lithium-ion batteries(LIBs),the industrialization of Si/C anodes is hampered by high-cost and low product yield.Herein,a high-yield strategy is developed in which photovoltaic waste silicon is converted to cost-effective graphitic Si/C composites(G-Si@C)for LIBs.The introduction of a binder improves the dispersion and compatibility of silicon and graphite,enhances particle sphericity,and significantly reduces the loss rate of the spray prilling process(from about 25%to 5%).As an LIB anode,the fabricated G-Si@C composites exhibit a capacity of 605 mAh g^(-1) after 1200 cycles.The cost of manufacturing Si/C anode materials has been reduced to approximately$7.47 kg^(-1),which is close to that of commercial graphite anode materials($5.0 kg^(-1)),and significantly lower than commercial Si/C materials(ca.$20.74 kg^(-1)).Moreover,the G-Si@C material provides approximately 81.0 Ah/$of capacity,which exceeds the current best commercial graphite anodes(70.0 Ah/$)and Si/C anodes(48.2 Ah/$).The successful implementation of this pathway will significantly promote the industrialization of high-energydensity Si/C anode materials.展开更多
At present,developing a simple strategy to effectively solve the shackles of volume expansion,poor conductivity and interface compatibility faced by Si-C anode in lithium batteries(LIBs)is the key to its commercializa...At present,developing a simple strategy to effectively solve the shackles of volume expansion,poor conductivity and interface compatibility faced by Si-C anode in lithium batteries(LIBs)is the key to its commercialization.Here,low-cost nano-Si powders were prepared from Si-waste of solar-cells by sanding treatment,which can effectively reduce the commercialization cost for Si-C anode.Furthermore,micro-nano structured Gr@Si/C/TiO_(2) anode materials with graphite(Gr)as the inner core,TiO_(2)-doped and carbon-coated Si as the outer coating-layer,were synthesized at kilogram-scale per milling batch.Comprehensive characterization results indicate that TiO_(2)-doped carbon layer can improve the interface compatibility with the electrolyte,further promote the reduction of electrode polarization,and finally enhance the battery performance for the Gr@Si/C/TiO_(2) anodes.Accordingly,Gr@Si/C/TiO_(2) composites can output excellent LIB performance,especially with high initial coulombic efficiency(ICE)of 82.51%and large average reversible capacity of~810 mA h g^(-1) at 0.8 A g^(-1) after 1000 cycles.Moreover,Gr@Si/C/TiO_(2)‖NCM811 pouch full cells deliver impressive performance especially with high energy density of~489.3 W h kg^(-1) based on the total weight of active materials,suggesting its promising application in the high performance LIBs.展开更多
Developing an effective method to synthesize high-performance high-voltage LiCoO_(2) is essential for its industrialization in lithium batteries(LIBs).This work proposes a simple mass-produced strategy for the first t...Developing an effective method to synthesize high-performance high-voltage LiCoO_(2) is essential for its industrialization in lithium batteries(LIBs).This work proposes a simple mass-produced strategy for the first time,that is,negative temperature coefficient thermosensitive Pr_(6)O_(11) nanoparticles are uniformly modified on LiCoO_(2) to prepare LiCoO_(2)@Pr_(6)O_(11)(LCO@PrO)via a liquid-phase mixing combined with annealing method.Tested at 274 mA g−1,the modified LCO@PrO electrodes deliver excellent 4.5 V high-voltage cycling performance with capacity retention ratios of 90.8%and 80.5%at 25 and 60℃,being much larger than those of 22.8%and 63.2%for bare LCO electrodes.Several effective strategies were used to clearly unveil the performance enhancement mechanism induced by Pr_(6)O_(11) modification.It is discovered that Pr_(6)O_(11) can improve interface compatibility,exhibit improved conductivity at elevated temperature,thus enhance the Li^(+)diffusion kinetics,and suppress the phase transformation of LCO and its resulting mechanical stresses.The 450 mAh LCO@PrO‖graphite pouch cells show excellent LIB performance and improved thermal safety characteristics.Importantly,the energy density of such pouch cell was increased even by~42%at 5 C.This extremely convenient technology is feasible for producing high-energy density LIBs with negligible cost increase,undoubtedly providing important academic inspiration for industrialization.展开更多
We aimed to develop a novel method for assessing the bitterness of azithromycin-containing reverse micelles(AM-containing RMs). Azithromycin-containing reverse mi-celles were prepared by processing Lipoid E80 and medi...We aimed to develop a novel method for assessing the bitterness of azithromycin-containing reverse micelles(AM-containing RMs). Azithromycin-containing reverse mi-celles were prepared by processing Lipoid E80 and medium chain triglycerides via a freeze-drying method. The bitterness threshold of azithromycin was determined by human tastetest, and an equation was derived to correlate the azithromycin concentrations and bitter-ness scores of standard solutions. Simulated salivary fluids and sampling times were fixedbased on the drug release profile of AM-containing RMs, with Zithromax ?(a commercialformulation of azithromycin) used as the control. The drug release concentrations fromstimulated salivary fluids were then used to assess the bitterness of AM-containing RMsand Zithromax ?. Afterward, the oral bioavailability of both formulations was evaluated byin vivo experiments in male Wistar rats. The results showed that the bitterness thresh-old of azithromycin standard solutions was between 25.3 μg/ml and 30.4 μg/ml. There-after, we calculated that the bitterness scores and the drug release concentrations of theazithromycin-containing reverse micelle formulation were similar to those of Zithromax ?ateach time point after 10 min of dispersal in simulated salivary fluid. In addition, the AUC 0-tafter oral administration of AM-containing RMs was 1.75-fold( P < 0.05) higher than that ofZithromax ?. In conclusions, a system for assessing bitterness was developed using an in vitrodrug release evaluation method and a human taste test panel. We found that the bitterness of azithromycin was successfully masked by reverse micelles, which also improved the oral bioavailability of azithromycin compared to that of Zithromax ?.展开更多
基金financially supported by the National Natural Science Foundation of China(Nos.22468029,52274408,52204314)the Major Science and Technology Projects in Yunnan Province(No.202402AF080005)+1 种基金Yunnan Fundamental Research Projects(No.202201AW070014)the Program for Innovative Research Team in the University of ministry of Education of China(No.IRT_17R48)
文摘Ultrafine metal nanoparticles are crucial for various applications,such as energy storage,catalysis,electronics,and biomedicine,owing to their high surfaceto-volume ratio and unique electronic properties.However,conventional nanoparticle synthesis methods often face challenges like irregular shapes and agglomeration,leading to compromised functionality.To address these challenges,this paper introduces a novel,rapid,high-temperature thermal radiation heating for the ultrafast synthesis and dispersion of metal nanoparticles.Utilizing the heating properties of carbon materials,the direct Joule heating generated by them rises to 1800-2000 K within~200 ms,followed by cooling to room temperature at a rate of 2×10^(3)K s^(-1).
基金supported by the Major Science and Technology Projects in Yunnan Province(Grant No.202402AF080005)National Natural Science Foundation of China(Grant Nos.52274408,22468029,52274412)+2 种基金Yunnan Fundamental Research Projects(Grant No.202201AW070014)the Program for Innovative Research Team in University of Ministry of Education of China(Grant No.IRT 17R48)the German Research Foundation(DFG,Project number 501766751).
文摘While silicon/carbon(Si/C)is considered one of the most promising anode materials for the next generation of high-energy lithium-ion batteries(LIBs),the industrialization of Si/C anodes is hampered by high-cost and low product yield.Herein,a high-yield strategy is developed in which photovoltaic waste silicon is converted to cost-effective graphitic Si/C composites(G-Si@C)for LIBs.The introduction of a binder improves the dispersion and compatibility of silicon and graphite,enhances particle sphericity,and significantly reduces the loss rate of the spray prilling process(from about 25%to 5%).As an LIB anode,the fabricated G-Si@C composites exhibit a capacity of 605 mAh g^(-1) after 1200 cycles.The cost of manufacturing Si/C anode materials has been reduced to approximately$7.47 kg^(-1),which is close to that of commercial graphite anode materials($5.0 kg^(-1)),and significantly lower than commercial Si/C materials(ca.$20.74 kg^(-1)).Moreover,the G-Si@C material provides approximately 81.0 Ah/$of capacity,which exceeds the current best commercial graphite anodes(70.0 Ah/$)and Si/C anodes(48.2 Ah/$).The successful implementation of this pathway will significantly promote the industrialization of high-energydensity Si/C anode materials.
基金jointly supported by the Natural Science Foundations of China(22179020,12174057)the Fujian Natural Science Foundation for Distinguished Young Scholars(2020J06042)+1 种基金the Foreign Science and Technology Cooperation Project of Fuzhou Science and Technology Bureau(2021-Y-086)the Cultivation plan of outstanding young scientific research talents of Fujian Education Department(J1-1323)。
文摘At present,developing a simple strategy to effectively solve the shackles of volume expansion,poor conductivity and interface compatibility faced by Si-C anode in lithium batteries(LIBs)is the key to its commercialization.Here,low-cost nano-Si powders were prepared from Si-waste of solar-cells by sanding treatment,which can effectively reduce the commercialization cost for Si-C anode.Furthermore,micro-nano structured Gr@Si/C/TiO_(2) anode materials with graphite(Gr)as the inner core,TiO_(2)-doped and carbon-coated Si as the outer coating-layer,were synthesized at kilogram-scale per milling batch.Comprehensive characterization results indicate that TiO_(2)-doped carbon layer can improve the interface compatibility with the electrolyte,further promote the reduction of electrode polarization,and finally enhance the battery performance for the Gr@Si/C/TiO_(2) anodes.Accordingly,Gr@Si/C/TiO_(2) composites can output excellent LIB performance,especially with high initial coulombic efficiency(ICE)of 82.51%and large average reversible capacity of~810 mA h g^(-1) at 0.8 A g^(-1) after 1000 cycles.Moreover,Gr@Si/C/TiO_(2)‖NCM811 pouch full cells deliver impressive performance especially with high energy density of~489.3 W h kg^(-1) based on the total weight of active materials,suggesting its promising application in the high performance LIBs.
基金jointly supported by the Natural Science Foundations of China(Nos.22179020,12174057)Fujian Natural Science Foundation for Distinguished Young Scholars(Grant No.2020J06042)+2 种基金Foreign science and technology cooperation project of Fuzhou Science and Technology Bureau(No.2021-Y-086)Natural Science Foundation of Fujian Province(Grant No.2018J01660)Cultivation plan of outstanding young scientific research talents of Fujian Education Department(Grant No.J1-1323).
文摘Developing an effective method to synthesize high-performance high-voltage LiCoO_(2) is essential for its industrialization in lithium batteries(LIBs).This work proposes a simple mass-produced strategy for the first time,that is,negative temperature coefficient thermosensitive Pr_(6)O_(11) nanoparticles are uniformly modified on LiCoO_(2) to prepare LiCoO_(2)@Pr_(6)O_(11)(LCO@PrO)via a liquid-phase mixing combined with annealing method.Tested at 274 mA g−1,the modified LCO@PrO electrodes deliver excellent 4.5 V high-voltage cycling performance with capacity retention ratios of 90.8%and 80.5%at 25 and 60℃,being much larger than those of 22.8%and 63.2%for bare LCO electrodes.Several effective strategies were used to clearly unveil the performance enhancement mechanism induced by Pr_(6)O_(11) modification.It is discovered that Pr_(6)O_(11) can improve interface compatibility,exhibit improved conductivity at elevated temperature,thus enhance the Li^(+)diffusion kinetics,and suppress the phase transformation of LCO and its resulting mechanical stresses.The 450 mAh LCO@PrO‖graphite pouch cells show excellent LIB performance and improved thermal safety characteristics.Importantly,the energy density of such pouch cell was increased even by~42%at 5 C.This extremely convenient technology is feasible for producing high-energy density LIBs with negligible cost increase,undoubtedly providing important academic inspiration for industrialization.
基金supported by The National Key Technologies R&D Program for New Drugs of China (2015ZX09J15104-003)
文摘We aimed to develop a novel method for assessing the bitterness of azithromycin-containing reverse micelles(AM-containing RMs). Azithromycin-containing reverse mi-celles were prepared by processing Lipoid E80 and medium chain triglycerides via a freeze-drying method. The bitterness threshold of azithromycin was determined by human tastetest, and an equation was derived to correlate the azithromycin concentrations and bitter-ness scores of standard solutions. Simulated salivary fluids and sampling times were fixedbased on the drug release profile of AM-containing RMs, with Zithromax ?(a commercialformulation of azithromycin) used as the control. The drug release concentrations fromstimulated salivary fluids were then used to assess the bitterness of AM-containing RMsand Zithromax ?. Afterward, the oral bioavailability of both formulations was evaluated byin vivo experiments in male Wistar rats. The results showed that the bitterness thresh-old of azithromycin standard solutions was between 25.3 μg/ml and 30.4 μg/ml. There-after, we calculated that the bitterness scores and the drug release concentrations of theazithromycin-containing reverse micelle formulation were similar to those of Zithromax ?ateach time point after 10 min of dispersal in simulated salivary fluid. In addition, the AUC 0-tafter oral administration of AM-containing RMs was 1.75-fold( P < 0.05) higher than that ofZithromax ?. In conclusions, a system for assessing bitterness was developed using an in vitrodrug release evaluation method and a human taste test panel. We found that the bitterness of azithromycin was successfully masked by reverse micelles, which also improved the oral bioavailability of azithromycin compared to that of Zithromax ?.
