目的探讨小剂量多巴胺联合重组人脑利钠肽(recombinant human brain natriuretic peptide,rhBNP)治疗心肌梗死(MI)后心力衰竭(HF)的临床效果及对患者系统性免疫炎症指数(SII)、三酰甘油葡萄糖乘积(TyG)指数的影响。方法选取64例MI后HF患...目的探讨小剂量多巴胺联合重组人脑利钠肽(recombinant human brain natriuretic peptide,rhBNP)治疗心肌梗死(MI)后心力衰竭(HF)的临床效果及对患者系统性免疫炎症指数(SII)、三酰甘油葡萄糖乘积(TyG)指数的影响。方法选取64例MI后HF患者,按随机数字表法分为对照组与观察组各32例,患者在入院后均给予常规治疗,对照组在常规治疗基础上给予rhBNP治疗,观察组在常规治疗基础上给予小剂量多巴胺联合rhBNP治疗。治疗7d后,观察2组患者血清SII、TyG指数与心功能指标[左室射血分数(LVEF)、前负荷率(EDFR)、外周血管阻力(SVR)]变化及临床效果、不良反应和主要不良心血管事件(MACE)发生情况。结果观察组患者治疗后SII、TyG水平低于对照组(P<0.05);心功能指标LVEF、SVR高于对照组,EDFR低于对照组(P<0.05)。观察组治疗总有效率(96.88%)高于对照组(84.38%)(P<0.05);治疗后6个月MACE发生率观察组(3.13%)低于对照组(18.75%)(P<0.05);用药不良反应发生率2组间比较差异无统计学意义(P>0.05)。结论采取小剂量多巴胺联合rhBNP用药方案治疗MI后HF,改善患者临床疗效、炎症状态及心功能较单一使用rhBNP效果更好,不明显增加不良事件发生率,值得基层医院参考应用。展开更多
Multi-wave exploration is an effective means for improving precision in the exploration and development of complex oil and gas reservoirs that are dense and have low permeability. However, convened wave data is charac...Multi-wave exploration is an effective means for improving precision in the exploration and development of complex oil and gas reservoirs that are dense and have low permeability. However, convened wave data is characterized by a low signal-to-noise ratio and low resolution, because the conventional deconvolution technology is easily affected by the frequency range limits, and there is limited scope for improving its resolution. The spectral inversion techniques is used to identify λ/8 thin layers and its breakthrough regarding band range limits has greatly improved the seismic resolution. The difficulty associated with this technology is how to use the stable inversion algorithm to obtain a high-precision reflection coefficient, and then to use this reflection coefficient to reconstruct broadband data for processing. In this paper, we focus on how to improve the vertical resolution of the converted PS-wave for multi-wave data processing. Based on previous research, we propose a least squares inversion algorithm with a total variation constraint, in which we uses the total variance as a priori information to solve under-determined problems, thereby improving the accuracy and stability of the inversion. Here, we simulate the Gaussian fitting amplitude spectrum to obtain broadband wavelet data, which we then process to obtain a higher resolution converted wave. We successfully apply the proposed inversion technology in the processing of high-resolution data from the Penglai region to obtain higher resolution convened wave data, which we then verify in a theoretical test. Improving the resolution of converted PS-wave data will provide more accurate data for subsequent velocity inversion and the extraction of reservoir reflection information.展开更多
目的探讨广西原发性肝癌患者血清中微囊藻毒素-LR(microcystin-LR,MC-LR)的空间分布规律。方法采集2015—2017年广西14个地级市原发性肝癌患者的静脉血,并采集当地的生活饮用水,采用酶联免疫吸附法测定血清和饮用水中的MC-LR浓度。采用...目的探讨广西原发性肝癌患者血清中微囊藻毒素-LR(microcystin-LR,MC-LR)的空间分布规律。方法采集2015—2017年广西14个地级市原发性肝癌患者的静脉血,并采集当地的生活饮用水,采用酶联免疫吸附法测定血清和饮用水中的MC-LR浓度。采用地理信息系统(geographic information system,GIS)空间插值分析技术和全局空间自相关评估广西肝癌患者血清中MC-LR浓度的空间分布特征及空间聚集性。采用GIS叠加分析观察血清中MC-LR与饮用水中MC-LR的空间分布吻合程度,并采用Pearson相关分析两者的相关程度。结果 GIS绘图显示广西肝癌患者血清中MC-LR浓度呈现'南高北低'的分布规律:高值地区主要包括崇左市、南宁市、防城港市和钦州市,低值地区主要包括桂林市等。全局自相关分析结果显示,广西肝癌患者血清中MC-LR浓度存在空间聚集性。GIS叠加分析显示,肝癌患者血清中MC-LR浓度的空间分布与饮用水中MC-LR浓度的空间分布吻合度较高。肝癌患者血清中MC-LR浓度与饮用水中MC-LR浓度呈统计学正相关(P<0.05)。结论广西地区原发性肝癌患者血清MC-LR浓度存在空间异质性,可能与当地饮用水中MC-LR的水平有关。展开更多
为了探究电动修复法对高浓度含铜污染土壤修复的可行性,对铜含量为1 500 mg/kg的污染土壤进行了电动修复。实验研究了不同修复时间下电流变化、土壤p H变化和土壤中铜的迁移规律,并采用BCR(Bureau Community of Reference)法对土壤中铜...为了探究电动修复法对高浓度含铜污染土壤修复的可行性,对铜含量为1 500 mg/kg的污染土壤进行了电动修复。实验研究了不同修复时间下电流变化、土壤p H变化和土壤中铜的迁移规律,并采用BCR(Bureau Community of Reference)法对土壤中铜的不同形态进行了分离、提取、测定。实验结果表明,电动修复技术对于高浓度含铜污染土壤中的铜具有良好的去除效果;在修复电压为30 V,修复时间为7 d时,土壤中的铜含量可以降至400 mg/kg以下。修复后铜的弱酸提取态占比增加,可还原态占比降低,可氧化态和残渣态占比无明显变化。展开更多
文摘目的探讨小剂量多巴胺联合重组人脑利钠肽(recombinant human brain natriuretic peptide,rhBNP)治疗心肌梗死(MI)后心力衰竭(HF)的临床效果及对患者系统性免疫炎症指数(SII)、三酰甘油葡萄糖乘积(TyG)指数的影响。方法选取64例MI后HF患者,按随机数字表法分为对照组与观察组各32例,患者在入院后均给予常规治疗,对照组在常规治疗基础上给予rhBNP治疗,观察组在常规治疗基础上给予小剂量多巴胺联合rhBNP治疗。治疗7d后,观察2组患者血清SII、TyG指数与心功能指标[左室射血分数(LVEF)、前负荷率(EDFR)、外周血管阻力(SVR)]变化及临床效果、不良反应和主要不良心血管事件(MACE)发生情况。结果观察组患者治疗后SII、TyG水平低于对照组(P<0.05);心功能指标LVEF、SVR高于对照组,EDFR低于对照组(P<0.05)。观察组治疗总有效率(96.88%)高于对照组(84.38%)(P<0.05);治疗后6个月MACE发生率观察组(3.13%)低于对照组(18.75%)(P<0.05);用药不良反应发生率2组间比较差异无统计学意义(P>0.05)。结论采取小剂量多巴胺联合rhBNP用药方案治疗MI后HF,改善患者临床疗效、炎症状态及心功能较单一使用rhBNP效果更好,不明显增加不良事件发生率,值得基层医院参考应用。
基金supported by the China National Petroleum Corporation Scientific research and technology development project(Nos.2013E-38-08)
文摘Multi-wave exploration is an effective means for improving precision in the exploration and development of complex oil and gas reservoirs that are dense and have low permeability. However, convened wave data is characterized by a low signal-to-noise ratio and low resolution, because the conventional deconvolution technology is easily affected by the frequency range limits, and there is limited scope for improving its resolution. The spectral inversion techniques is used to identify λ/8 thin layers and its breakthrough regarding band range limits has greatly improved the seismic resolution. The difficulty associated with this technology is how to use the stable inversion algorithm to obtain a high-precision reflection coefficient, and then to use this reflection coefficient to reconstruct broadband data for processing. In this paper, we focus on how to improve the vertical resolution of the converted PS-wave for multi-wave data processing. Based on previous research, we propose a least squares inversion algorithm with a total variation constraint, in which we uses the total variance as a priori information to solve under-determined problems, thereby improving the accuracy and stability of the inversion. Here, we simulate the Gaussian fitting amplitude spectrum to obtain broadband wavelet data, which we then process to obtain a higher resolution converted wave. We successfully apply the proposed inversion technology in the processing of high-resolution data from the Penglai region to obtain higher resolution convened wave data, which we then verify in a theoretical test. Improving the resolution of converted PS-wave data will provide more accurate data for subsequent velocity inversion and the extraction of reservoir reflection information.
文摘目的探讨广西原发性肝癌患者血清中微囊藻毒素-LR(microcystin-LR,MC-LR)的空间分布规律。方法采集2015—2017年广西14个地级市原发性肝癌患者的静脉血,并采集当地的生活饮用水,采用酶联免疫吸附法测定血清和饮用水中的MC-LR浓度。采用地理信息系统(geographic information system,GIS)空间插值分析技术和全局空间自相关评估广西肝癌患者血清中MC-LR浓度的空间分布特征及空间聚集性。采用GIS叠加分析观察血清中MC-LR与饮用水中MC-LR的空间分布吻合程度,并采用Pearson相关分析两者的相关程度。结果 GIS绘图显示广西肝癌患者血清中MC-LR浓度呈现'南高北低'的分布规律:高值地区主要包括崇左市、南宁市、防城港市和钦州市,低值地区主要包括桂林市等。全局自相关分析结果显示,广西肝癌患者血清中MC-LR浓度存在空间聚集性。GIS叠加分析显示,肝癌患者血清中MC-LR浓度的空间分布与饮用水中MC-LR浓度的空间分布吻合度较高。肝癌患者血清中MC-LR浓度与饮用水中MC-LR浓度呈统计学正相关(P<0.05)。结论广西地区原发性肝癌患者血清MC-LR浓度存在空间异质性,可能与当地饮用水中MC-LR的水平有关。
文摘为了探究电动修复法对高浓度含铜污染土壤修复的可行性,对铜含量为1 500 mg/kg的污染土壤进行了电动修复。实验研究了不同修复时间下电流变化、土壤p H变化和土壤中铜的迁移规律,并采用BCR(Bureau Community of Reference)法对土壤中铜的不同形态进行了分离、提取、测定。实验结果表明,电动修复技术对于高浓度含铜污染土壤中的铜具有良好的去除效果;在修复电压为30 V,修复时间为7 d时,土壤中的铜含量可以降至400 mg/kg以下。修复后铜的弱酸提取态占比增加,可还原态占比降低,可氧化态和残渣态占比无明显变化。
