目的探讨血清补体C1q/肿瘤坏死因子相关蛋白13(CTRP13)与妊娠期糖尿病(GDM)的相关性.方法选取GDM患者为GDM组(n=55),正常妊娠者为NGT组(n=50).对比两组基线资料及血清CTRP13水平.Logistic回归分析GDM影响因素,Pearson相关性分析血清CTR...目的探讨血清补体C1q/肿瘤坏死因子相关蛋白13(CTRP13)与妊娠期糖尿病(GDM)的相关性.方法选取GDM患者为GDM组(n=55),正常妊娠者为NGT组(n=50).对比两组基线资料及血清CTRP13水平.Logistic回归分析GDM影响因素,Pearson相关性分析血清CTRP13与临床指标的相关性,多元线性回归分析血清CTRP13的影响因素.结果相较于NGT组,GDM组FPG、1hPG、2hPG、FIns、HOMA-IR、HbA1c、IL-6、TNF-α增高,血清CTRP13水平降低(56.90±10.73 ng/mL vs 75.98±15.20 ng/mL)(P<0.05).两组年龄、孕周、BMI、SBP、DBP、TG、TC、LDL-C、HDL-C比较差异无统计学意义(P>0.05).血清CTRP13与FPG、1hPG、2hPG、HOMA-IR、IL-6及TNF-α呈负相关(P<0.05).FPG、IL-6是CTRP13的影响因素.HOMA-IR及CTRP13是GDM的影响因素.结论GDM患者血清CTRP13低表达,是GDM的独立危险因素,CTRP13可能参与GDM病程进展.展开更多
Matrix porosity calculations of fractured and vuggy reservoirs, such as volcanics and weathered dolomite, are one of the problems urgently needed to solve in well-log evaluation. In this paper, we first compare the an...Matrix porosity calculations of fractured and vuggy reservoirs, such as volcanics and weathered dolomite, are one of the problems urgently needed to solve in well-log evaluation. In this paper, we first compare the an empirical formula for porosity calculation from full diameter rhyolite core experiments with the matrix porosity formulas commonly used. We discuss the applicability of the empirical formula in fractured and vuggy reservoirs, such as intermediate-basic volcanics and weathered dolomite. Based on core analysis data, the error distribution of the calculated porosity of our empirical formula and the other porosity formulas in these reservoirs are given. The statistical error analysis indicates that the our empirical formula provides a higher precision than the other porosity formulas. When the porosity is between 1.5% and 15%, the acoustic experiment formula can be used not only for acidic volcanics but also in other fractured and vuggy reservoirs, such as intermediate-basic volcanics and weathered dolomite. Moreover, the formula can reduce the effects of borehole enlargement and rock alteration on porosity computation.展开更多
Laboratory studies showed that addition of about 0.5%(in mass)Li_(2)CO_(3).to the anode used in an aluminium electrolysis cell gave increased wetting of the anode by the cryolite-alumina melt,increased critical curren...Laboratory studies showed that addition of about 0.5%(in mass)Li_(2)CO_(3).to the anode used in an aluminium electrolysis cell gave increased wetting of the anode by the cryolite-alumina melt,increased critical current density and reduced anodic overvoltage.The lithium carbonate then acted as a catalyst for the oxidation reaction between the anode carbon and the oxide-containing ions in the melt.Anode paste containing lithium carbonate has been employed in Chinese aluminium smelters with 62 kA HSS cells.This lead to improved current efficiency,reduced cell voltage and energy consumption,as well as fewer anode effects per day.展开更多
Neuroin fil ammation contributes to neuronal death in cerebral ischemia.Urolithin A(UA),a gut microbial metabolite of ellagic acid,has emerged as a potential antiinflammatory agent.However,its roles and precise mechan...Neuroin fil ammation contributes to neuronal death in cerebral ischemia.Urolithin A(UA),a gut microbial metabolite of ellagic acid,has emerged as a potential antiinflammatory agent.However,its roles and precise mechanisms in stroke remain unknown.Riphenyltetrazolium chloride(TTC)staining was employed to assess cerebral infarct volume.The Morris water maze was used to detect cognitive function.A terminal deoxynucleotidyl transferase dUTP nick-end labeling(TUNEL)assay was performed to detect neuronal apoptosis.展开更多
文摘目的探讨血清补体C1q/肿瘤坏死因子相关蛋白13(CTRP13)与妊娠期糖尿病(GDM)的相关性.方法选取GDM患者为GDM组(n=55),正常妊娠者为NGT组(n=50).对比两组基线资料及血清CTRP13水平.Logistic回归分析GDM影响因素,Pearson相关性分析血清CTRP13与临床指标的相关性,多元线性回归分析血清CTRP13的影响因素.结果相较于NGT组,GDM组FPG、1hPG、2hPG、FIns、HOMA-IR、HbA1c、IL-6、TNF-α增高,血清CTRP13水平降低(56.90±10.73 ng/mL vs 75.98±15.20 ng/mL)(P<0.05).两组年龄、孕周、BMI、SBP、DBP、TG、TC、LDL-C、HDL-C比较差异无统计学意义(P>0.05).血清CTRP13与FPG、1hPG、2hPG、HOMA-IR、IL-6及TNF-α呈负相关(P<0.05).FPG、IL-6是CTRP13的影响因素.HOMA-IR及CTRP13是GDM的影响因素.结论GDM患者血清CTRP13低表达,是GDM的独立危险因素,CTRP13可能参与GDM病程进展.
基金sponsored by the Science Research and Technology Development Project of Petrochina Company Limited "Well Logging Interpretation and Integrative Evaluation of the Complex Lithology"(Grant No.2008A-2705)
文摘Matrix porosity calculations of fractured and vuggy reservoirs, such as volcanics and weathered dolomite, are one of the problems urgently needed to solve in well-log evaluation. In this paper, we first compare the an empirical formula for porosity calculation from full diameter rhyolite core experiments with the matrix porosity formulas commonly used. We discuss the applicability of the empirical formula in fractured and vuggy reservoirs, such as intermediate-basic volcanics and weathered dolomite. Based on core analysis data, the error distribution of the calculated porosity of our empirical formula and the other porosity formulas in these reservoirs are given. The statistical error analysis indicates that the our empirical formula provides a higher precision than the other porosity formulas. When the porosity is between 1.5% and 15%, the acoustic experiment formula can be used not only for acidic volcanics but also in other fractured and vuggy reservoirs, such as intermediate-basic volcanics and weathered dolomite. Moreover, the formula can reduce the effects of borehole enlargement and rock alteration on porosity computation.
基金Supported by the National Natural Science Foundation of China。
文摘Laboratory studies showed that addition of about 0.5%(in mass)Li_(2)CO_(3).to the anode used in an aluminium electrolysis cell gave increased wetting of the anode by the cryolite-alumina melt,increased critical current density and reduced anodic overvoltage.The lithium carbonate then acted as a catalyst for the oxidation reaction between the anode carbon and the oxide-containing ions in the melt.Anode paste containing lithium carbonate has been employed in Chinese aluminium smelters with 62 kA HSS cells.This lead to improved current efficiency,reduced cell voltage and energy consumption,as well as fewer anode effects per day.
文摘Neuroin fil ammation contributes to neuronal death in cerebral ischemia.Urolithin A(UA),a gut microbial metabolite of ellagic acid,has emerged as a potential antiinflammatory agent.However,its roles and precise mechanisms in stroke remain unknown.Riphenyltetrazolium chloride(TTC)staining was employed to assess cerebral infarct volume.The Morris water maze was used to detect cognitive function.A terminal deoxynucleotidyl transferase dUTP nick-end labeling(TUNEL)assay was performed to detect neuronal apoptosis.
