Diagnosis of soil salinity and characterizing its spatial variability both vertically and horizontally are needed to establish control measures in irrigated agriculture. In this regard, it is essential that salinity d...Diagnosis of soil salinity and characterizing its spatial variability both vertically and horizontally are needed to establish control measures in irrigated agriculture. In this regard, it is essential that salinity development in varying soil depths be known temporally and spatially. Apparent soil electrical conductivity, measured by electromagnetic induction instruments, has been widely used as an auxiliary variable to estimate spatial distribution of field soil salinity. The main objectives of this paper were adopted a mobile electromagnetic induction (EMI) system to perform field electromagnetic (EM) survey in different soil layers, to evaluate the uncertainty through Inverse Distance Weighted (IDW) and Ordinary Kriging (OK) methods, and to determine which algorithm is more reliable for the local and spatial uncertainty assessment. Results showed that EM38 data from apparent soil electrical conductivity are highly correlated with salinity, more accurate for estimating salinity from multiple linear regression models, which the correlation coefficient of 0 - 20, 20 - 40, 40 - 60 and 60 - 80 cm were 0.9090, 0.9228, 0.896 and 0.9085 respectively. The comparison showed that the prediction accuracy of two methods also displays good performance for soil salinity, the estimation precision of IDW method (with E = 0.8873, 0.9075, 0.8483 and 0.901, RPD = 9.64, 8.01, 8.17 and 11.23 in 0 - 20, 20 - 40. 40 - 60 and 60 - 80 cm soil layers, respectively) was superior to that of OK (with E = 0.8857, 0.872, 0.8744 and 0.8822, RPD = 9.44, 7.83, 8.52 and 10.88, respectively), but differences of two methods in predictions are not significant. The obtained salinity map was helpful to display the spatial patterns of soil salinity and monitor and evaluate the management of salinity.展开更多
The production of hydrogen peroxide(H_(2)O_(2))via artificial photosynthesis using single-atom semiconductor photocatalysts represents a promising green and sustainable technology.However,its efficiency is still limit...The production of hydrogen peroxide(H_(2)O_(2))via artificial photosynthesis using single-atom semiconductor photocatalysts represents a promising green and sustainable technology.However,its efficiency is still limited by sluggish water oxidation kinetics,poor photogenerated charge separation,and insufficient O_(2)adsorption and activation capabilities.Herein,uniformly dispersed single-atom catalysts(SACs)with a Co-N_(4)coordination structure have been synthesized by thermally transforming cobalt phthalocyanine(CoPc)assemblies pre-anchored on phosphate functionalized reduced graphene oxide(Co@rGO-P),and then used to construct heterojunctions with perylenetetracarboxylic acid(PTA)nanosheets for photocatalytic H_(2)O_(2)production by an in-situ growth method.The optimized Co@rGO-P/PTA achieved an H_(2)O_(2)production rate of 1.4 mmol g^(-1)h^(-1)in pure water,with a 12.9-fold enhancement compared to pristine PTA nanosheets exhibiting competitive photoactivity among reported perylene-based materials.Femtosecond transient absorption spectra,in-situ diffuse reflectance infrared Fourier transform spectra and theoretical calculations reveal that the exceptional performance is attributed to the enhanced electron transfer from PTA to rGO via the phosphate bridge and then to the Co-N_(4),and to the promoted O_(2)adsorption and activation at Co-N_(4)active sites.This work provides a feasible and effective strategy for designing highly efficient single-atom semiconductor heterojunction photocatalysts for H_(2)O_(2)production.展开更多
目的 探讨血清孤独G蛋白偶联受体配体-13(solitary G protein-coupled receptor ligand-13,Apelin-13)、碱性成纤维细胞生长因子(fibroblast growth factor 2,FGF2)、中枢神经特异蛋白(central nervous system specific protein B,S100B...目的 探讨血清孤独G蛋白偶联受体配体-13(solitary G protein-coupled receptor ligand-13,Apelin-13)、碱性成纤维细胞生长因子(fibroblast growth factor 2,FGF2)、中枢神经特异蛋白(central nervous system specific protein B,S100B)水平与脑卒中后抑郁(post-stroke depression, PSD)的关系。方法 回顾性分析河南科技大学附属黄河医院/黄河三门峡医院2022年4月至2024年1月收治的260例脑卒中患者临床资料,随访1个月,参考17项汉密尔顿抑郁量表(Hamilton Depression Rating Scale, HAMD-17)评估结果统计PSD发生率,并将其分为发生组和未发生组,比较两组血清Apelin-13、FGF2、S100B水平及其他临床资料,采用Logistic回归模型分析PSD发生的影响因素;绘制受试者工作特征曲线(Receiver operating characteristic curve, ROC)评价血清Apelin-13、FGF2、S100B对PSD的预测价值。结果 PSD发生率为37.31%;与未发生组比较,发生组女性、糖尿病、左侧大脑半球病灶占比、美国国立卫生研究院卒中量表(national Institutes of health stroke scale, NIHSS)评分、同型半胱氨酸水平、系统性免疫炎症指数(systemic immune-inflammatory index, SII)、血清Apelin-13、S100B水平较高(P<0.05),月均可支配医疗费用、血清FGF2水平较低(P<0.05);月均可支配医疗费用(OR=0.732,95%CI:0.599~0.894)、左侧大脑半球病灶(OR=1.478,95%CI:1.159~1.885)、NIHSS评分(OR=1.293,95%CI:1.095~1.527)、同型半胱氨酸水平(OR=1.278,95%CI:1.058~1.542)、SII(OR=1.370,95%CI:1.133~1.657)、Apelin-13水平(OR=1.278,95%CI:1.086~1.503)、FGF2水平(OR=0.807,95%CI:0.689~0.946)、S100B水平(OR=1.357,95%CI:1.089~1.690)为PSD发生的影响因素(P<0.05);血清Apelin-13、FGF2、S100B联合预测PSD的灵敏度高于单独预测,曲线下面积(area under curve, AUC)高于单独预测方法(P<0.05),特异度与单独预测基本一致。结论 血清Apelin-13、FGF2、S100B水平与月均可支配医疗费用、左侧大脑半球病灶、NIHSS评分、同型半胱氨酸、SII可能是PSD发生的影响因素,且血清Apelin-13、FGF2、S100B可能对PSD有预测价值,其中联合预测价值更显著。展开更多
Rib spalling is a highly severe issue during mining in deep-buried large-mining-height working faces.This study takes Zhaogu No.2 Coal Mine in Jiaozuo Coalfield,China,as the research background and carries out three f...Rib spalling is a highly severe issue during mining in deep-buried large-mining-height working faces.This study takes Zhaogu No.2 Coal Mine in Jiaozuo Coalfield,China,as the research background and carries out three focused works to address this problem.Firstly,field measurements were conducted to clarify rib spalling characteristics:the coal wall is dominated by shear failure,internal cracks are mainly distributed 3–6 m above the coal wall surface,and the maximum depth of crack development reaches 3 m.Secondly,Universal Distinct Element Code(UDEC)numerical simulation software was used to build a rib spalling model,with the Trigon model adopted to divide the coal wall into blocks.Analysis of four key factors shows that increased buried depth and mining height significantly raise the total length of coal wall internal cracks,increasing rib spalling risk,while higher coal body strength and support strength effectively alleviate this phenomenon.Finally,an orthogonal experiment was designed to quantitatively determine the influence degree of the four factors on rib spalling.Results show that coal body strength has the greatest impact,followed by support strength,mining height,and mining depth in order of influence.This study provides valuable theoretical guidance for on-site prevention and control of coal wall rib spalling.展开更多
The recovery of lithium from spent lithium-ion batteries(LIBs)is of great importance in addressing lithium shortages and environmental issues.In this study,a novel and clean process for selective separation of lithium...The recovery of lithium from spent lithium-ion batteries(LIBs)is of great importance in addressing lithium shortages and environmental issues.In this study,a novel and clean process for selective separation of lithium from spent LiFePO_(4)cathode material by low temperature oxidative roasting and water leaching was proposed.The effect of several important factors,such as roasting temperature,roasting time,and molar ratio of ferric chloride(FeCl_(3)·6H_(2)O)to lithium iron phosphate(LFP),on the leaching efficiency of lithium and iron was systematically investigated by using single factor experimental method.The results show that approximately 97.1%lithium element was recovered by being converted to water-soluble LiCl at a roasting temperature 350℃,a roasting time 120 min and a FeCl_(3)·6H_(2)O/LFP molar ratio of 1:1,and iron element was enriched in the leaching residue in the form of insoluble FePO_(4).High-purity lithium carbonate products could be prepared from the leching solution by adding Na_(2)CO_(3) after removing iron.The establishment of new cleaning process can provide a scalable,environmentally friendly and simple way to recover valuable metals from spent LFP batteries.展开更多
目的:探讨Gremlin-1、血尿酸(SUA)及骨代谢指标表达水平与骨质疏松患者疾病严重程度的相关性及其联合诊断价值。方法:选取我院2019年1月到2020年12月收治的80例骨质疏松患者,对所有患者依照双X线吸收法诊断结果进行严重程度分组,将骨密...目的:探讨Gremlin-1、血尿酸(SUA)及骨代谢指标表达水平与骨质疏松患者疾病严重程度的相关性及其联合诊断价值。方法:选取我院2019年1月到2020年12月收治的80例骨质疏松患者,对所有患者依照双X线吸收法诊断结果进行严重程度分组,将骨密度-2.5<T<-1患者分为骨量减少组(n=23),将骨密度T≤-2.5患者分为骨质疏松症组(n=37),将骨密度T≤-2.5,且发生过骨质疏松性骨折的患者分为严重骨质疏松症组(n=20)。对比三组患者Gremlin-1、SUA表达水平与骨代谢指标表达水平,采用Spearman相关分析Gremlin-1、SUA及骨代谢指标表达水平与骨质疏松患者疾病严重程度的相关性。最后建立ROC曲线,Gremlin-1、SUA及骨代谢指标联合对骨质疏松症的诊断价值。结果:三组患者Gremlin-1、SUA水平对比差异显著,骨量减少组Gremlin-1高于骨质疏松症组和严重骨质疏松症组,SUA低于骨质疏松症组和严重骨质疏松症组(P<0.05);三组患者维生素D3[25-(OD)-D3]、β-胶原特殊序列(β-CTX)、甲状旁腺激素(PTH)、I型前胶原N端肽(N-terminal peptide of type I procollagen,PINP)、骨钙素(OC)相关骨代谢指标水平对比差异显著,骨量减少组25-(OD)-D3、PINP、OC高于骨质疏松症组和严重骨质疏松症组,β-CTX、PTH低于骨质疏松症组和严重骨质疏松症组(P<0.05);SUA(r=-0.636)、β-CTX(r=00.626)、PTH(r=0.625)的表达与骨质疏松患者疾病严重程度呈正相关,Gremlin-1(r=-0.452)、25-(OD)-D3(r=-0.462)、PINP(r=-0.622)、OC(r=-0.426)的表达与骨质疏松患者疾病严重程度呈负相关(P<0.05);Gremlin-1、SUA及骨代谢指标联合对骨质疏松症诊断的曲线下面积为0.688,敏感度为92.53%、特异度为87.49%,显著高于单一指标诊断(P<0.05)。结论:Gremlin-1、SUA及骨代谢指标与骨质疏松病情严重程度具有密切关系,且联合诊断骨质疏松症敏感度及特异度较高。展开更多
Perilla frutescens(Perilla leaf), a garnishing vegetable in East Asian countries, as well as a plant-based medicine, has been used for centuries to treat various conditions, including depression. Several studies have ...Perilla frutescens(Perilla leaf), a garnishing vegetable in East Asian countries, as well as a plant-based medicine, has been used for centuries to treat various conditions, including depression. Several studies have demonstrated that the essential oil of P. frutescens(EOPF) attenuated the depressive-like behavior in mice. The present study was designed to test the anti-depressant effects of EOPF and the possible mechanisms in an chronic, unpredictable, mild stress(CUMS)-induced mouse model. With the exposure to stressor once daily for five consecutive weeks, EOPF(3, 6, and 9 mg·kg-1) and a positive control drug fluoxetine(20 mg·kg-1) were administered through gastric intubation to mice once daily for three consecutive weeks from the 3rd week. Open-field test, sucrose consumption test, tail suspension test(TST), and forced swimming test(FST) were used to evaluate the behavioral activity. The contents of 5-hydroxytryptamine(5-HT) and its metabolite, 5-hydroxyindoleacetic acid(5-HIAA), in mouse hippocampus were determined by HPLC–ECD. Serum interleukin(IL)-1, IL-6, and tumor necrosis factor(TNF)-α levels were evaluated by enzyme-linked immunosorbent assay(ELISA). The results showed that CUMS significantly decreased the levels of 5-HT and 5-HIAA in the hippocampus, with an increase in plasma IL-6, IL-1β, and TNF-α levels. CUMS also reduced open-field activity, sucrose consumption, as well as increased immobility duration in FST and TST. EOPF administration could effectively reverse the alterations in the concentrations of 5-HT and 5-HIAA; reduce the IL-6, IL-1β, and TNF-α levels. Moreover, EOPF could effectively reverse alterations in immobility duration, sucrose consumption, and open-field activity. However, the effect was not dose-dependent. In conclusion, EOPF administration exhibited significant antidepressant-like effects in mice with CUMS-induced depression. The antidepressant activity of EOPF might be related to the relation between alteration of serotonergic responses and anti-inflammatory effects.展开更多
The stability of room mining coal pillars during their secondary mining for recovering coal was analyzed. An analysis was performed for the damage and instability mechanism of coal pillars recovered by the caving mini...The stability of room mining coal pillars during their secondary mining for recovering coal was analyzed. An analysis was performed for the damage and instability mechanism of coal pillars recovered by the caving mining method. During the damage progression of a single room coal pillar, the shape of the stress distribution in the pillar transformed from the initial stable saddle shape to the final arch-shaped distribution of critical instability. By combining the shapes of stress distribution in the coal pillars with the ultimate strength theory, the safe-stress value of coal pillar was obtained as 11.8 MPa. The mechanism of instability of coal pillar groups recovered by the caving mining method was explained by the domino effect. Since the room coal pillars mined and recovered by the traditional caving mining method were significantly influenced by the secondary mining during recovery, the coal pillars would go through a chain-type instability failure. Because of this limitation, the method of solid backfilling was proposed for mining and recovering room coal pillars, thus changing the transfer mechanism of stress caused by the secondary mining(recovery) of coal pillars. The mechanical model of the stope in the case of backfilling and recovering room coal pillars was built. The peak stress values inside coal pillars varied with the variance of backfilling ratio when the working face was advanced by 150 m. Furthermore, when the critical backfilling ratio was 80.6%, the instability failure of coal pillars would not occur during the solid backfill mining process. By taking Bandingliang Coal Mine as an example, the coal pillars' stability of stope under this backfilling ratio was studied, and a project scheme was designed.展开更多
文摘Diagnosis of soil salinity and characterizing its spatial variability both vertically and horizontally are needed to establish control measures in irrigated agriculture. In this regard, it is essential that salinity development in varying soil depths be known temporally and spatially. Apparent soil electrical conductivity, measured by electromagnetic induction instruments, has been widely used as an auxiliary variable to estimate spatial distribution of field soil salinity. The main objectives of this paper were adopted a mobile electromagnetic induction (EMI) system to perform field electromagnetic (EM) survey in different soil layers, to evaluate the uncertainty through Inverse Distance Weighted (IDW) and Ordinary Kriging (OK) methods, and to determine which algorithm is more reliable for the local and spatial uncertainty assessment. Results showed that EM38 data from apparent soil electrical conductivity are highly correlated with salinity, more accurate for estimating salinity from multiple linear regression models, which the correlation coefficient of 0 - 20, 20 - 40, 40 - 60 and 60 - 80 cm were 0.9090, 0.9228, 0.896 and 0.9085 respectively. The comparison showed that the prediction accuracy of two methods also displays good performance for soil salinity, the estimation precision of IDW method (with E = 0.8873, 0.9075, 0.8483 and 0.901, RPD = 9.64, 8.01, 8.17 and 11.23 in 0 - 20, 20 - 40. 40 - 60 and 60 - 80 cm soil layers, respectively) was superior to that of OK (with E = 0.8857, 0.872, 0.8744 and 0.8822, RPD = 9.44, 7.83, 8.52 and 10.88, respectively), but differences of two methods in predictions are not significant. The obtained salinity map was helpful to display the spatial patterns of soil salinity and monitor and evaluate the management of salinity.
文摘The production of hydrogen peroxide(H_(2)O_(2))via artificial photosynthesis using single-atom semiconductor photocatalysts represents a promising green and sustainable technology.However,its efficiency is still limited by sluggish water oxidation kinetics,poor photogenerated charge separation,and insufficient O_(2)adsorption and activation capabilities.Herein,uniformly dispersed single-atom catalysts(SACs)with a Co-N_(4)coordination structure have been synthesized by thermally transforming cobalt phthalocyanine(CoPc)assemblies pre-anchored on phosphate functionalized reduced graphene oxide(Co@rGO-P),and then used to construct heterojunctions with perylenetetracarboxylic acid(PTA)nanosheets for photocatalytic H_(2)O_(2)production by an in-situ growth method.The optimized Co@rGO-P/PTA achieved an H_(2)O_(2)production rate of 1.4 mmol g^(-1)h^(-1)in pure water,with a 12.9-fold enhancement compared to pristine PTA nanosheets exhibiting competitive photoactivity among reported perylene-based materials.Femtosecond transient absorption spectra,in-situ diffuse reflectance infrared Fourier transform spectra and theoretical calculations reveal that the exceptional performance is attributed to the enhanced electron transfer from PTA to rGO via the phosphate bridge and then to the Co-N_(4),and to the promoted O_(2)adsorption and activation at Co-N_(4)active sites.This work provides a feasible and effective strategy for designing highly efficient single-atom semiconductor heterojunction photocatalysts for H_(2)O_(2)production.
基金supported by the National Key Research and Development Program of China(No.2023YFC2907501)the National Natural Science Foundation of China(No.52374106)+1 种基金the China Postdoctoral Science Foundation(Grant no.2024T171006)the National Natural Science Foundation of China(Grant no.52204163).
文摘Rib spalling is a highly severe issue during mining in deep-buried large-mining-height working faces.This study takes Zhaogu No.2 Coal Mine in Jiaozuo Coalfield,China,as the research background and carries out three focused works to address this problem.Firstly,field measurements were conducted to clarify rib spalling characteristics:the coal wall is dominated by shear failure,internal cracks are mainly distributed 3–6 m above the coal wall surface,and the maximum depth of crack development reaches 3 m.Secondly,Universal Distinct Element Code(UDEC)numerical simulation software was used to build a rib spalling model,with the Trigon model adopted to divide the coal wall into blocks.Analysis of four key factors shows that increased buried depth and mining height significantly raise the total length of coal wall internal cracks,increasing rib spalling risk,while higher coal body strength and support strength effectively alleviate this phenomenon.Finally,an orthogonal experiment was designed to quantitatively determine the influence degree of the four factors on rib spalling.Results show that coal body strength has the greatest impact,followed by support strength,mining height,and mining depth in order of influence.This study provides valuable theoretical guidance for on-site prevention and control of coal wall rib spalling.
基金Projects(52074069,52174314)supported by the National Natural Science Foundation of ChinaProject(E2021501029)supported by the Natural Science Foundation of Hebei Province,China+2 种基金Project(E2022501030)supported by the Natural Science Foundation-Steel,the Iron Foundation of Hebei Province,ChinaProject(22567627H)supported by Performance subsidy Fund for Key Laboratory of Dielectric and Electrolyte Functional Material Hebei Province,ChinaProject(24464402D)supported by S&T Program of Hebei Province,China。
文摘The recovery of lithium from spent lithium-ion batteries(LIBs)is of great importance in addressing lithium shortages and environmental issues.In this study,a novel and clean process for selective separation of lithium from spent LiFePO_(4)cathode material by low temperature oxidative roasting and water leaching was proposed.The effect of several important factors,such as roasting temperature,roasting time,and molar ratio of ferric chloride(FeCl_(3)·6H_(2)O)to lithium iron phosphate(LFP),on the leaching efficiency of lithium and iron was systematically investigated by using single factor experimental method.The results show that approximately 97.1%lithium element was recovered by being converted to water-soluble LiCl at a roasting temperature 350℃,a roasting time 120 min and a FeCl_(3)·6H_(2)O/LFP molar ratio of 1:1,and iron element was enriched in the leaching residue in the form of insoluble FePO_(4).High-purity lithium carbonate products could be prepared from the leching solution by adding Na_(2)CO_(3) after removing iron.The establishment of new cleaning process can provide a scalable,environmentally friendly and simple way to recover valuable metals from spent LFP batteries.
文摘目的:探讨Gremlin-1、血尿酸(SUA)及骨代谢指标表达水平与骨质疏松患者疾病严重程度的相关性及其联合诊断价值。方法:选取我院2019年1月到2020年12月收治的80例骨质疏松患者,对所有患者依照双X线吸收法诊断结果进行严重程度分组,将骨密度-2.5<T<-1患者分为骨量减少组(n=23),将骨密度T≤-2.5患者分为骨质疏松症组(n=37),将骨密度T≤-2.5,且发生过骨质疏松性骨折的患者分为严重骨质疏松症组(n=20)。对比三组患者Gremlin-1、SUA表达水平与骨代谢指标表达水平,采用Spearman相关分析Gremlin-1、SUA及骨代谢指标表达水平与骨质疏松患者疾病严重程度的相关性。最后建立ROC曲线,Gremlin-1、SUA及骨代谢指标联合对骨质疏松症的诊断价值。结果:三组患者Gremlin-1、SUA水平对比差异显著,骨量减少组Gremlin-1高于骨质疏松症组和严重骨质疏松症组,SUA低于骨质疏松症组和严重骨质疏松症组(P<0.05);三组患者维生素D3[25-(OD)-D3]、β-胶原特殊序列(β-CTX)、甲状旁腺激素(PTH)、I型前胶原N端肽(N-terminal peptide of type I procollagen,PINP)、骨钙素(OC)相关骨代谢指标水平对比差异显著,骨量减少组25-(OD)-D3、PINP、OC高于骨质疏松症组和严重骨质疏松症组,β-CTX、PTH低于骨质疏松症组和严重骨质疏松症组(P<0.05);SUA(r=-0.636)、β-CTX(r=00.626)、PTH(r=0.625)的表达与骨质疏松患者疾病严重程度呈正相关,Gremlin-1(r=-0.452)、25-(OD)-D3(r=-0.462)、PINP(r=-0.622)、OC(r=-0.426)的表达与骨质疏松患者疾病严重程度呈负相关(P<0.05);Gremlin-1、SUA及骨代谢指标联合对骨质疏松症诊断的曲线下面积为0.688,敏感度为92.53%、特异度为87.49%,显著高于单一指标诊断(P<0.05)。结论:Gremlin-1、SUA及骨代谢指标与骨质疏松病情严重程度具有密切关系,且联合诊断骨质疏松症敏感度及特异度较高。
基金supported by the Priority Academic Program Development of Jiangsu Higher Education Institutionsthe Natural Science Foundation of Jiangsu Province of China(No.BK2011630)
文摘Perilla frutescens(Perilla leaf), a garnishing vegetable in East Asian countries, as well as a plant-based medicine, has been used for centuries to treat various conditions, including depression. Several studies have demonstrated that the essential oil of P. frutescens(EOPF) attenuated the depressive-like behavior in mice. The present study was designed to test the anti-depressant effects of EOPF and the possible mechanisms in an chronic, unpredictable, mild stress(CUMS)-induced mouse model. With the exposure to stressor once daily for five consecutive weeks, EOPF(3, 6, and 9 mg·kg-1) and a positive control drug fluoxetine(20 mg·kg-1) were administered through gastric intubation to mice once daily for three consecutive weeks from the 3rd week. Open-field test, sucrose consumption test, tail suspension test(TST), and forced swimming test(FST) were used to evaluate the behavioral activity. The contents of 5-hydroxytryptamine(5-HT) and its metabolite, 5-hydroxyindoleacetic acid(5-HIAA), in mouse hippocampus were determined by HPLC–ECD. Serum interleukin(IL)-1, IL-6, and tumor necrosis factor(TNF)-α levels were evaluated by enzyme-linked immunosorbent assay(ELISA). The results showed that CUMS significantly decreased the levels of 5-HT and 5-HIAA in the hippocampus, with an increase in plasma IL-6, IL-1β, and TNF-α levels. CUMS also reduced open-field activity, sucrose consumption, as well as increased immobility duration in FST and TST. EOPF administration could effectively reverse the alterations in the concentrations of 5-HT and 5-HIAA; reduce the IL-6, IL-1β, and TNF-α levels. Moreover, EOPF could effectively reverse alterations in immobility duration, sucrose consumption, and open-field activity. However, the effect was not dose-dependent. In conclusion, EOPF administration exhibited significant antidepressant-like effects in mice with CUMS-induced depression. The antidepressant activity of EOPF might be related to the relation between alteration of serotonergic responses and anti-inflammatory effects.
基金Project(2014ZDPY02)supported by the Fundamental Research Funds for the Central Universities
文摘The stability of room mining coal pillars during their secondary mining for recovering coal was analyzed. An analysis was performed for the damage and instability mechanism of coal pillars recovered by the caving mining method. During the damage progression of a single room coal pillar, the shape of the stress distribution in the pillar transformed from the initial stable saddle shape to the final arch-shaped distribution of critical instability. By combining the shapes of stress distribution in the coal pillars with the ultimate strength theory, the safe-stress value of coal pillar was obtained as 11.8 MPa. The mechanism of instability of coal pillar groups recovered by the caving mining method was explained by the domino effect. Since the room coal pillars mined and recovered by the traditional caving mining method were significantly influenced by the secondary mining during recovery, the coal pillars would go through a chain-type instability failure. Because of this limitation, the method of solid backfilling was proposed for mining and recovering room coal pillars, thus changing the transfer mechanism of stress caused by the secondary mining(recovery) of coal pillars. The mechanical model of the stope in the case of backfilling and recovering room coal pillars was built. The peak stress values inside coal pillars varied with the variance of backfilling ratio when the working face was advanced by 150 m. Furthermore, when the critical backfilling ratio was 80.6%, the instability failure of coal pillars would not occur during the solid backfill mining process. By taking Bandingliang Coal Mine as an example, the coal pillars' stability of stope under this backfilling ratio was studied, and a project scheme was designed.
