Dear Editor,The life of mammals begins with the fertilization of an egg by sperm,resulting in the formation of a zygote.This zygote then embarks on a complex developmental journey,undergoing successive rounds of cell ...Dear Editor,The life of mammals begins with the fertilization of an egg by sperm,resulting in the formation of a zygote.This zygote then embarks on a complex developmental journey,undergoing successive rounds of cell division,differentiation,and growth,eventually giving rise to a fully formed organism(Rossant,2018).This intricate process is tightly regulated by mechanisms such as cell polarity,epigenetic modifications,signaling pathways,metabolic cues,and key transcription factors(TFs)(Xu et al.,2021,2025).展开更多
基金supported by the National Key R&D Pro gram of China(2021YFA1100300)the National Nat ural Science Foundation of China(32430016,U21A20195,32500489,32570685).
文摘Dear Editor,The life of mammals begins with the fertilization of an egg by sperm,resulting in the formation of a zygote.This zygote then embarks on a complex developmental journey,undergoing successive rounds of cell division,differentiation,and growth,eventually giving rise to a fully formed organism(Rossant,2018).This intricate process is tightly regulated by mechanisms such as cell polarity,epigenetic modifications,signaling pathways,metabolic cues,and key transcription factors(TFs)(Xu et al.,2021,2025).
