Nondestructive measurement technology of phenotype can provide substantial phenotypic data support for applications such as seedling breeding,management,and quality testing.The current method of measuring seedling phe...Nondestructive measurement technology of phenotype can provide substantial phenotypic data support for applications such as seedling breeding,management,and quality testing.The current method of measuring seedling phenotypes mainly relies on manual measurement which is inefficient,subjective and destroys samples.Therefore,the paper proposes a nondestructive measurement method for the canopy phenotype of the watermelon plug seedlings based on deep learning.The Azure Kinect was used to shoot canopy color images,depth images,and RGB-D images of the watermelon plug seedlings.The Mask-RCNN network was used to classify,segment,and count the canopy leaves of the watermelon plug seedlings.To reduce the error of leaf area measurement caused by mutual occlusion of leaves,the leaves were repaired by CycleGAN,and the depth images were restored by image processing.Then,the Delaunay triangulation was adopted to measure the leaf area in the leaf point cloud.The YOLOX target detection network was used to identify the growing point position of each seedling on the plug tray.Then the depth differences between the growing point and the upper surface of the plug tray were calculated to obtain plant height.The experiment results show that the nondestructive measurement algorithm proposed in this paper achieves good measurement performance for the watermelon plug seedlings from the 1 true-leaf to 3 true-leaf stages.The average relative error of measurement is 2.33%for the number of true leaves,4.59%for the number of cotyledons,8.37%for the leaf area,and 3.27%for the plant height.The experiment results demonstrate that the proposed algorithm in this paper provides an effective solution for the nondestructive measurement of the canopy phenotype of the plug seedlings.展开更多
In low-light environments,captured images often exhibit issues such as insufficient clarity and detail loss,which significantly degrade the accuracy of subsequent target recognition tasks.To tackle these challenges,th...In low-light environments,captured images often exhibit issues such as insufficient clarity and detail loss,which significantly degrade the accuracy of subsequent target recognition tasks.To tackle these challenges,this study presents a novel low-light image enhancement algorithm that leverages virtual hazy image generation through dehazing models based on statistical analysis.The proposed algorithm initiates the enhancement process by transforming the low-light image into a virtual hazy image,followed by image segmentation using a quadtree method.To improve the accuracy and robustness of atmospheric light estimation,the algorithm incorporates a genetic algorithm to optimize the quadtree-based estimation of atmospheric light regions.Additionally,this method employs an adaptive window adjustment mechanism to derive the dark channel prior image,which is subsequently refined using morphological operations and guided filtering.The final enhanced image is reconstructed through the hazy image degradation model.Extensive experimental evaluations across multiple datasets verify the superiority of the designed framework,achieving a peak signal-to-noise ratio(PSNR)of 17.09 and a structural similarity index(SSIM)of 0.74.These results indicate that the proposed algorithm not only effectively enhances image contrast and brightness but also outperforms traditional methods in terms of subjective and objective evaluation metrics.展开更多
The landscape of hepatobiliary surgical education has undergone a significanttransformation with the integration of advanced technologies such as threedimensionalmodeling,virtual reality,augmented reality,and artifici...The landscape of hepatobiliary surgical education has undergone a significanttransformation with the integration of advanced technologies such as threedimensionalmodeling,virtual reality,augmented reality,and artificial intelligence.This review synthesizes recent advancements in surgical education,examiningthe role of these technologies in improving anatomical understanding,surgicalskill acquisition,and overall trainee engagement.Evidence from randomizedcontrolled trials,systematic reviews,and cohort studies shows that immersivetraining tools,including virtual reality,augmented reality,and haptic feedback,outperform traditional apprenticeship methods in fostering cognitive and psychomotorskills.Artificial intelligence applications provide real-time feedback,furtherenhancing learning efficiency.However,these technologies should complement,rather than replace,traditional hands-on training.Some challenges remain to beaddressed,such as high costs,infrastructure requirements,and limited long-termvalidation of these technologies.The review concludes that while these innovationsoffer promising educational benefits,further research is needed to standardizetheir application and evaluate their long-term impact on surgical outcomes.展开更多
Membrane-initiated estrogen receptorα(mERα)signaling has been shown to affect bone mass in murine models.However,it remains unknown which cell types mediate the mERα-dependent effects on bone.In this study,we gener...Membrane-initiated estrogen receptorα(mERα)signaling has been shown to affect bone mass in murine models.However,it remains unknown which cell types mediate the mERα-dependent effects on bone.In this study,we generated a novel mouse model with a conditional C451A mutation in Esr1,which enables selective knockout of the palmitoylation site essential for the membrane localization of ERα(C451A^(f/f)).First,we used Runx2-Cre mice to generate Runx2-C451A^(f/f)mice with conditional inactivation of mERαsignaling in Runx2-expressing osteoblast lineage cells.No significant changes were observed in body weight,weights of estrogen-responsive organs,or serum concentrations of estradiol between female Runx2-C451A^(f/f)and homozygous C451A^(f/f)littermate controls.High-resolution microcomputed tomography analysis showed a consistent decrease in cortical bone mass in the tibia,femur,and vertebra L5 of Runx2-C451A^(f/f)mice and three-point bending analysis of humerus revealed an impaired mechanical bone strength in Runx2-C451A^(f/f)female mice compared to controls.Additionally,primary osteoblast cultures from mice lacking mERαsignaling showed impaired differentiation compared to controls.展开更多
The crosstalk between megakaryocytic lineage cells and the skeletal system has just begun to be explored but remains largely elusive.Using conditional gene knockout mouse models,we demonstrated that loss of Beclin 1(B...The crosstalk between megakaryocytic lineage cells and the skeletal system has just begun to be explored but remains largely elusive.Using conditional gene knockout mouse models,we demonstrated that loss of Beclin 1(Becn1),a major regulator of mammalian autophagy,exclusively in the megakaryocytic lineage disrupted autophagy in platelets but did not compromise megakaryopoiesis or the formation and function of platelets.Unexpectedly,conditional Becn1 deletion in male mice led to a remarkable increase in bone mass with improved bone quality,in association with a decrease in sex hormone binding globulin(SHBG)and an increase in free testosterone(FT).In vivo Becn1 overexpression in megakaryocytic lineage-specific cells reduced bone mass and quality,along with an increase in SHBG and a decrease in FT.Transplantation of wild-type bone marrow cells into megakaryocytic lineage Becn1-deficient male mice restored bone mass and normalized SHBG and FT.Furthermore,bilateral orchiectomy of Becn1^(f/f);Pf4-iCre mice,which are crippled with the production of testosterone,resulted in a reduction in bone mass and quality,whereas in vivo overexpression of SHBG,specifically in the liver of Becn1^(f/f);Pf4-iCre mice,decreased FT and reduced bone mass and quality.In addition,metformin treatment,which induces SHBG expression,reduced FT and normalized bone mass in Becn1^(f/f);Pf4-iCre mice.We thus concluded that Becn1 of the megakaryocytic lineage is dispensable locally for platelet hemostasis but limits bone mass by increasing SHBG,which in turn reduces the FT of male mice.Our findings highlight a mechanism by which Becn1 from megakaryocytic lineage cells distally balances bone growth.展开更多
Ce-β-Bi_(2)O_(3)/AgI was prepared using solvothermal calcination and in-situ deposition methods.The introduction of Ce can inhibit the conversion of Bi_(2)O_(3)fromβtoαphase at high temperatures,promoting the forma...Ce-β-Bi_(2)O_(3)/AgI was prepared using solvothermal calcination and in-situ deposition methods.The introduction of Ce can inhibit the conversion of Bi_(2)O_(3)fromβtoαphase at high temperatures,promoting the formation of oxygen vacancies(OVs)in the photocatalyst.OVs can adsorb more dissolved oxygen to promote the formation rate of·O^(-)_(2).Moreover,the interaction between Ce-Bi_(2)O_(3)and AgI results in the formation of Z-scheme heterojunctions,which can broaden the light absorption region,facilitate photogenerated carrier separation and transfer and enhance the ability to produce more active oxygen species(ROS).The morphology,crystal,element distribution and photo-electric chemical properties of the Ce-Bi_(2)O_(3)/AgI were analyzed,and the result shows that the optimal ratio of Ce-Bi_(2)O_(3)/AgI photocatalyst achieves a removal rate of 88.63%(180 min)of tetracycline(TC)(20 mg/L)and 100%(120 min)of methyl orange(MO)(20 mg/L).This work clarified the photocatalytic degradation mechanism,providing a promising avenue for developing photocatalytic composites by rare earth metal doping in environme ntal remediation applications.展开更多
Non-destructive time-series assessment of chlorophyll content in flag-leaf(FLC)accurately mimics the senescence rate and the identification of genetic loci associated with senescence provides valuable knowledge to imp...Non-destructive time-series assessment of chlorophyll content in flag-leaf(FLC)accurately mimics the senescence rate and the identification of genetic loci associated with senescence provides valuable knowledge to improve yield stability under stressed environments.In this study,we employed both unmanned aerial vehicles(UAVs)equipped with red–green–blue(RGB)camera and ground-based SPAD-502 instrument to conduct temporal phenotyping of senescence.A total of 262 recombinant inbred lines derived from the cross of Zhongmai 578/Jimai 22 were evaluated for senescence-related traits across three environments,spanning from heading to 35 d post-anthesis.The manual senescence rate(MSR)was quantified using the FLC and the active accumulated temperature,and UAV derived vegetation index were utilized to assess the stay-green rate(USG)facilitating the identification of senescent and stay-green lines.Results indicated that higher senescence rates significantly impacted grain yield,primarily by influencing thousand-kernel weight,and plant height.Quantitative trait loci(QTL)mapping for FLC,USG,and MSR using the 50K SNP array identified 38 stable loci associated with RGB-based vegetation indices and senescence-related traits:among which 19 loci related to senescence traits from UAV and FLC were consistently detected across at least two growth stages,with nine loci likely representing novel QTL.This study highlights the potential of UAV-based high-throughput phenotyping and phenology in identifying critical loci associated with senescence rates in wheat,validating the relationship between senescence rates and yield-related traits in wheat,offering valuable opportunities for gene discovery and significant applications in breeding programs.展开更多
The development of high-performance transition metal sulfide(TMS)/carbon composites to replace conventional graphite anode remains a critical challenge for advancing lithium-ion batteries(LIBs).In this study,a facile ...The development of high-performance transition metal sulfide(TMS)/carbon composites to replace conventional graphite anode remains a critical challenge for advancing lithium-ion batteries(LIBs).In this study,a facile self-sacrifice template method is developed to prepare FeS encapsulated into N,S co-doped carbon(FeS/NSC)composite using melamine-cyanuric acid(MCA)supermolecule as a multifunctional template precursor.The function of MCA supermolecule for material synthesis is explored,revealing its special function as a dispersant,dopant and pore-forming agent.Furthermore,the effect of Fe source dosage on the morphology,structure and composition of the final products is explored.The resultant FeS/NSC-0.1(where 0.1 represents the mass of added Fe source)exhibits the most optimal proportion,characterized by a good dispersion status of FeS within the NSC matrix,effective N,S co-doping and ample porosity.Benefiting from these merits,the FeS/NSC-0.1 anode demonstrates significantly improved cycling stability and rate capability when compared to the counterparts.Undoubtedly,this work offers a universal method to produce advanced transition metal sulfide/carbon composite electrodes for energy storage and conversion systems.展开更多
Prostate cancer(PCa)is characterized by high incidence and propensity for easy metastasis,presenting significant challenges in clinical diagnosis and treatment.Tumor microenvironment(TME)-responsive nanomaterials prov...Prostate cancer(PCa)is characterized by high incidence and propensity for easy metastasis,presenting significant challenges in clinical diagnosis and treatment.Tumor microenvironment(TME)-responsive nanomaterials provide a promising prospect for imaging-guided precision therapy.Considering that tumor-derived alkaline phosphatase(ALP)is over-expressed in metastatic PCa,it makes a great chance to develop a theranostics system with ALP responsive in the TME.Herein,an ALP-responsive aggregationinduced emission luminogens(AIEgens)nanoprobe AMNF self-assembly was designed for enhancing the diagnosis and treatment of metastatic PCa.The nanoprobe exhibited self-aggregation in the presence of ALP resulted in aggregation-induced fluorescence,and enhanced accumulation and prolonged retention period at the tumor site.In terms of detection,the fluorescence(FL)/computed tomography(CT)/magnetic resonance(MR)multi-mode imaging effect of nanoprobe was significantly improved post-aggregation,enabling precise diagnosis through the amalgamation of multiple imaging modes.Enhanced CT/MR imaging can achieve assist preoperative tumor diagnosis,and enhanced FL imaging technology can achieve“intraoperative visual navigation”,showing its potential application value in clinical tumor detection and surgical guidance.In terms of treatment,AMNF showed strong absorption in the near infrared region after aggregation,which improved the photothermal treatment effect.Overall,our work developed an effective aggregation-enhanced theranostic strategy for ALP-related cancers.展开更多
The urgent demand for clean energy solutions has intensified the search for advanced storage materials,with rechargeable alkali-ion batteries(AIBs)playing a pivotal role in electrochemical energy storage.Enhancing ele...The urgent demand for clean energy solutions has intensified the search for advanced storage materials,with rechargeable alkali-ion batteries(AIBs)playing a pivotal role in electrochemical energy storage.Enhancing electrode performance is critical to addressing the increasing need for high-energy and high-power AIBs.Next-generation anode materials face significant challenges,including limited energy storage capacities and complex reaction mechanisms that complicate structural modeling.Sn-based materials have emerged as promising candidates for AIBs due to their inherent advantages.Recent research has increasingly focused on the development of heterojunctions as a strategy to enhance the performance of Sn-based anode materials.Despite significant advances in this field,comprehensive reviews summarizing the latest developments are still sparse.This review provides a detailed overview of recent progress in Sn-based heterojunction-type anode materials.It begins with an explanation of the concept of heterojunctions,including their fabrication,characterization,and classification.Cutting-edge research on Sn-based heterojunction-type anodes for AIBs is highlighted.Finally,the review summarizes the latest advancements in heterojunction technology and discusses future directions for research and development in this area.展开更多
The study on sand body connectivity and distribution patterns is of great significance for well emplacement and injection-production pattern analysis in the A oilfield of the Weixi?nan Sag currently at a pre-developme...The study on sand body connectivity and distribution patterns is of great significance for well emplacement and injection-production pattern analysis in the A oilfield of the Weixi?nan Sag currently at a pre-development stage.Based on the current drilling data,seismic data,and fault development characteristics,this study investigates the connectivity,geometric morphology,planar distribution,and vertical evolution of composite sand bodies(multi-stage superimposed channel sand bodies)within the fault block using seismic forward and inversion modeling.The El3I oil layer group in the third member of the Liushagang Formation is developed in the fan delta-front sub-facies,which mainly consists of subaqueous distributary channels.The thickness of single-stage subaqueous distributary channel sand bodies ranges from 2 to 6 m,and the width of composite channel sand bodies varies from 50 to 100 m.Under the long-term transgression background,the subaqueous distributary channels in the El3I oil layer group are relatively narrow,forming superimposed and continuous composite channel sand bodies through lateral migration and vertical stacking.The long-term base-level cycles control the width of subaqueous distributary channels,while the mid-term base-level cycles control the thickness of these channels.The subaqueous distributary channels developed during the late stage of mid-term base-level fall are thicker than those formed during the early stage.Accordingly,quantitative relationships between channel thickness and width are established for the early and late stages of mid-term base-level fall,to finely depict the evolution patterns of channel sand body geometry and stacking styles across different stages.These findings provide important guidance for accurately predicting the planar distribution and channel width of composite subaqueous distributary channels at different stages of the mid-term baselevel cycles.展开更多
Longitudinal magnetic field annealing is utilized for modifying the magnetic anisotropy and enhancing the magnetic softness of Fe_(75)Co_(8)(B_(10)Si_(3)C_(3)P_(1))_(1-x)/_(17)Cux(x=0.5,0.75,1,1.25)nanocrystalline all...Longitudinal magnetic field annealing is utilized for modifying the magnetic anisotropy and enhancing the magnetic softness of Fe_(75)Co_(8)(B_(10)Si_(3)C_(3)P_(1))_(1-x)/_(17)Cux(x=0.5,0.75,1,1.25)nanocrystalline alloys.All of the magnetic field-annealed nanocrystalline alloys with Cu content more than 0.5 at.%exhibit significantly improved soft-magnetic properties,including high saturation magnetic flux density up to 1.87 T,effective permeability of 13,000-16,000 under the condition of 1 A/m and 1 kHz,coercivity as low as 1.6 A/m,and core loss of 0.11-0.45 W/kg under the condition of 1.0 T and 50 Hz.The application of a magnetic field promotes the nucleation and inhibits the growth of grains,leading to an increase in the number density of nanocrystals and the crystalline volume fraction,and a reduction in the grain size.The magnetic field annealing reduces the effective magneto-crystalline anisotropy energy to 2-4 J/m^(3),and induces longitudinal magnetic anisotropy with anisotropy energy density of 400-900 J/m^(3)which shows dependence on the crystalline volume fraction.The field-induced magnetic anisotropy dominates over the random local magnetic anisotropies,and results in the formation of regular magnetic domains aligned longitudinally,pinning-free domain wall displacement,and thus enhanced soft-magnetic properties.展开更多
Injection-production coupling(IPC) technology holds substantial potential for boosting oil recovery and enhancing economic efficiency.Despite this potential,discussion on gas injection coupling,especially in relation ...Injection-production coupling(IPC) technology holds substantial potential for boosting oil recovery and enhancing economic efficiency.Despite this potential,discussion on gas injection coupling,especially in relation to microscopic mechanisms,remains relatively sparse.This study utilizes microscopic visualization experiments to investigate the mechanisms of residual oil mobilization under various IPC scenarios,complemented by mechanical analysis at different stages.The research quantitatively assesses the degree of microscopic oil recovery and the distribution of residual oil across different injection-production methods.Findings reveal that during the initial phase of continuous gas injection(CGI),the process closely mimics miscible displacement,gradually transitioning to immiscible displacement as CO_(2)extraction progresses.Compared to CGI,the asynchronous injection-production(AIP) method improved the microscopic oil recovery rate by 6.58%.This enhancement is mainly attributed to significant variations in the pressure field in the AIP method,which facilitate the mobilization of columnar and porous re sidual oil.Furthermo re,the synchronous cycle injection(SCI) method increased microscopic oil recovery by 13.77% and 7.19% compared to CGI and AIP,respectively.In the SCI method,membrane oil displays filame ntary and Karman vo rtex street flow patterns.The dissolved and expanded crude oil te nds to accumulate and grow at the oil-solid interface due to adhesive forces,thereby reducing migration resistance.The study findings provide a theoretical foundation for improving oil recovery in lowpermeability reservoirs.展开更多
A martensitic initial microstructure before hot forming was prepared by direct quenching after hot rolling of the hot formed steel and the effect of such initial microstructure on mechanical properties of steel was an...A martensitic initial microstructure before hot forming was prepared by direct quenching after hot rolling of the hot formed steel and the effect of such initial microstructure on mechanical properties of steel was analyzed. The process of direct quenching after hot rolling which replaced the steps of coiling and cold rolling was termed as compact process. As the temperature before direct quenching falls within the non-recrystallization range, the deformed austenite grains exhibit flattened morphology along the hot rolling direction, and the high-density dislocations and significant strain energy in deformed austenite are inherited by directly quenched martensite. Moreover, due to promotion of austenite nucleation and subsequent recrystallization during the reverse transformation process in hot forming, both reversed austenite grains and martensite laths are significantly refined. Compared to the conventional process with an initial microstructure consisting of fully recrystallized ferrite and cementite, the compact process reduces average prior austenite grain sizes from 12.5 to 5.5 μm and martensite lath widths from 202 to 123 nm. Additionally, the compact process results in a higher density of dislocations in test steel, leading to maximum yield strength (1294 MPa) and ultimate tensile strength (2266 MPa). Compared to conventional process, this compact process significantly improves the mechanical properties of the hot formed steels while simplifying the production.展开更多
Thiol-ene click polymerization has become an effective synthetic tool for constructing diverse sulfurcontaining polymers with advanced functions.However,the polymerization of internal alkene and thiol has been rarely ...Thiol-ene click polymerization has become an effective synthetic tool for constructing diverse sulfurcontaining polymers with advanced functions.However,the polymerization of internal alkene and thiol has been rarely used to prepare functional polymers because of large steric hindrance and relatively weak reactivity.In this work,a base-catalyzed click polymerization of thiols and internal olefins was successfully established in air.Notably,the polymerization went smoothly in halogen-containing solvent even without any catalyst via a radical step-growth polymerization.The polymerization enjoys excellent monomer applicability,which affords 16 well-defined polythioethers in high yields(up to 99%)with high molecular weights(Mwup to 19,600),good thermal stability(Td,5%up to 326℃),broadly regulated glass transition temperatures(-24~95℃),and unconventional fluorescence.Via a simple solvent regulation strategy,the vanillin-derived polythioether could be used as a turn-off fluorescence probe for Fe3+ions in DMF/H2O and a turn-on probe for Ag+ions in THF,with low detection limits of 9.15×10^(-7)mol/L and 4.60×10^(-7)mol/L,respectively.Additionally,the detection of Ag+presented a transformation from a clear solution to an emulsion,expanding the application prospects through observing colorimetric and fluorescent dual signals.Thus,this work not only holds significance in establishing an efficient polymerization,but also provides a strategy to prepare sensitive fluorescent probes for multiple metal ions.展开更多
Siberian taimen Hucho taimen(Pallas,1773)is a broadly distributed and popular sport fish with high economic value.However,low abundance and hard-to-reach habitat make the Siberian taimen a relatively understudied spec...Siberian taimen Hucho taimen(Pallas,1773)is a broadly distributed and popular sport fish with high economic value.However,low abundance and hard-to-reach habitat make the Siberian taimen a relatively understudied species.Here we describe the morphological variability of two size groups of Siberian taimen juveniles from the eastern(Amur River basin)and western(Kama River basin)parts of the species distribution.The largest morphological differentiation of Siberian taimen juveniles was observed at the inter-basin level.In the Amur River basin,Siberian taimen juveniles also differed morphologically even at sites located at a distance of 20 km from each other,which may be explained by a small home-range inhabitation of juveniles leading to the formation of their morphotype determined by local environmental conditions.The pattern of allometry varies in taimen from different rivers,which could be related to the ontogenetic shift of ecological niches and the level of heterogeneity of the river environment.展开更多
Electron-positron colliders operating in the GeV center-of-mass range,or tau-charm energy region,have been proved to enable competitive frontier research due to several unique features.With the progress of high-energy...Electron-positron colliders operating in the GeV center-of-mass range,or tau-charm energy region,have been proved to enable competitive frontier research due to several unique features.With the progress of high-energy physics in the last two decades,a new-generation Tau-Charm factory,called the Super Tau-Charm Facility(STCF),has been actively promoted by the particle physics community in China.STCF has the potential to address fundamental questions such as the essence of color confinement and the matter-antimatter asymmetry within the next decades.The main design goals of the STCF are a center-of-mass energy ranging from 2 to 7 GeV and a luminosity surpassing 5×10^(34)cm^(−2)s^(−1)that is optimized at a center-of-mass energy of 4 GeV,which is approximately 50 times that of the currently operating Tau-Charm factory-BEPCII.The STCF accelerator has two main parts:a double-ring collider with a crab-waist collision scheme and an injector that provides top-up injections for both electron and positron beams.As a typical third-generation electron-positron circular collider,the STCF accelerator faces many challenges in both accelerator physics and technology.In this paper,the conceptual design of the STCF accelerator complex is presented,including the ongoing efforts and plans for technological research and develop-ment,as well as the required infrastructure.The STCF project aims to secure support from the Chinese central government for its construction during the 15th Five-Year Plan(2026-2030).展开更多
Black point is a black discoloration of the grain embryo that reduces the grain quality and commodity grade.Identifying the underlying genetic loci can facilitate the improvement of black point resistance in wheat.Her...Black point is a black discoloration of the grain embryo that reduces the grain quality and commodity grade.Identifying the underlying genetic loci can facilitate the improvement of black point resistance in wheat.Here,262 recombinant inbred lines(RILs)from the cross of Zhongmai 578/Jimai 22 were evaluated for their black point reactions in fve environments.A high-density genetic linkage map of the RIL population was constructed with the wheat 50K single nucleotide polymorphism(SNP)array.Six stable QTLs for black point resistance were detected,QBp.caas-2A,QBp.caas-2B1,QBp.caas-2B2,QBp.caas-2D,QBp.caas-3A,and QBp.caas-5B,which explained 2.1-28.8%of the phenotypic variances.The resistance alleles of QBp.caas-2B1 and QBp.caas-2B2 were contributed by Zhongmai 578 while the others were from Jimai 22.QBp.caas-2B2,QBp.caas-2D and QBp.caas-3A overlapped with previously reported loci,whereas QBp.caas-2A,QBp.caas-2B1 and QBp.caas-5B are likely to be new.Five kompetitive allele-specifc PCR(KASP)markers,Kasp_2A_BP,Kasp_2B1_BP,Kasp_2B2_BP,Kasp_3A_BP,and Kasp_5B_BP,were validated in a natural population of 165 cultivars.The fndings of this study provide useful QTLs and molecular markers for the improvement of black point resistance in wheat through marker-assisted breeding.展开更多
Antibiotics are crucial medications for preventing and treating bacterial infections.However,due to their inherent resistance to degradation,they are also a major component of water pollutants.Semiconductor photocatal...Antibiotics are crucial medications for preventing and treating bacterial infections.However,due to their inherent resistance to degradation,they are also a major component of water pollutants.Semiconductor photocatalysis is considered to be an important green technology for sewage treatment.In this study,BiVO_(4)/Cd S Z-type heterojunction was synthesized and applied in the photocatalytic degradation of tetracycline hydrochloride(TCH).The Z-type heterojunction not only facilitates the separation of photogenerated charges,but also preserves photogenerated electrons with strong reduction capability and photogenerated holes with high oxidation capability.Following visible light irradiation for 90 min,the efficiency of BiVO_(4)/Cd S photocatalytic degradation of TCH reached 93.1%.Moreover,BiVO_(4)/Cd S demonstrates notable degradation efficacy toward other quinolone antibiotics.Free radical trapping experiments and EPR test results suggest that superoxide radicals,hydroxyl radicals,photogenerated electrons,and holes serve as the primary active species in the photocatalytic degradation process of tetracycline hydrochloride.This study offers valuable insights into the development of Z-type heterojunction photocatalysts for the efficient degradation of tetracycline hydrochloride.展开更多
基金funded by the National Key Research and Development Program of China(Grant No.2019YFD1001900)the HZAU-AGIS Cooperation Fund(Grant No.SZYJY2022006).
文摘Nondestructive measurement technology of phenotype can provide substantial phenotypic data support for applications such as seedling breeding,management,and quality testing.The current method of measuring seedling phenotypes mainly relies on manual measurement which is inefficient,subjective and destroys samples.Therefore,the paper proposes a nondestructive measurement method for the canopy phenotype of the watermelon plug seedlings based on deep learning.The Azure Kinect was used to shoot canopy color images,depth images,and RGB-D images of the watermelon plug seedlings.The Mask-RCNN network was used to classify,segment,and count the canopy leaves of the watermelon plug seedlings.To reduce the error of leaf area measurement caused by mutual occlusion of leaves,the leaves were repaired by CycleGAN,and the depth images were restored by image processing.Then,the Delaunay triangulation was adopted to measure the leaf area in the leaf point cloud.The YOLOX target detection network was used to identify the growing point position of each seedling on the plug tray.Then the depth differences between the growing point and the upper surface of the plug tray were calculated to obtain plant height.The experiment results show that the nondestructive measurement algorithm proposed in this paper achieves good measurement performance for the watermelon plug seedlings from the 1 true-leaf to 3 true-leaf stages.The average relative error of measurement is 2.33%for the number of true leaves,4.59%for the number of cotyledons,8.37%for the leaf area,and 3.27%for the plant height.The experiment results demonstrate that the proposed algorithm in this paper provides an effective solution for the nondestructive measurement of the canopy phenotype of the plug seedlings.
基金supported by the Natural Science Foundation of Shandong Province(nos.ZR2023MF047,ZR2024MA055 and ZR2023QF139)the Enterprise Commissioned Project(nos.2024HX104 and 2024HX140)+1 种基金the China University Industry-University-Research Innovation Foundation(nos.2021ZYA11003 and 2021ITA05032)the Science and Technology Plan for Youth Innovation of Shandong's Universities(no.2019KJN012).
文摘In low-light environments,captured images often exhibit issues such as insufficient clarity and detail loss,which significantly degrade the accuracy of subsequent target recognition tasks.To tackle these challenges,this study presents a novel low-light image enhancement algorithm that leverages virtual hazy image generation through dehazing models based on statistical analysis.The proposed algorithm initiates the enhancement process by transforming the low-light image into a virtual hazy image,followed by image segmentation using a quadtree method.To improve the accuracy and robustness of atmospheric light estimation,the algorithm incorporates a genetic algorithm to optimize the quadtree-based estimation of atmospheric light regions.Additionally,this method employs an adaptive window adjustment mechanism to derive the dark channel prior image,which is subsequently refined using morphological operations and guided filtering.The final enhanced image is reconstructed through the hazy image degradation model.Extensive experimental evaluations across multiple datasets verify the superiority of the designed framework,achieving a peak signal-to-noise ratio(PSNR)of 17.09 and a structural similarity index(SSIM)of 0.74.These results indicate that the proposed algorithm not only effectively enhances image contrast and brightness but also outperforms traditional methods in terms of subjective and objective evaluation metrics.
文摘The landscape of hepatobiliary surgical education has undergone a significanttransformation with the integration of advanced technologies such as threedimensionalmodeling,virtual reality,augmented reality,and artificial intelligence.This review synthesizes recent advancements in surgical education,examiningthe role of these technologies in improving anatomical understanding,surgicalskill acquisition,and overall trainee engagement.Evidence from randomizedcontrolled trials,systematic reviews,and cohort studies shows that immersivetraining tools,including virtual reality,augmented reality,and haptic feedback,outperform traditional apprenticeship methods in fostering cognitive and psychomotorskills.Artificial intelligence applications provide real-time feedback,furtherenhancing learning efficiency.However,these technologies should complement,rather than replace,traditional hands-on training.Some challenges remain to beaddressed,such as high costs,infrastructure requirements,and limited long-termvalidation of these technologies.The review concludes that while these innovationsoffer promising educational benefits,further research is needed to standardizetheir application and evaluate their long-term impact on surgical outcomes.
基金supported by the Swedish Research Council(2017-01286,2020-01840)the Swedish state under the agreement between the Swedish government and the county councils(ALF-agreement)(ALFGBG721581)+2 种基金the Gustaf V 80-years fund(FAI-2018-0466)the IngaBritt and Arne Lundberg Foundation(LU2017-0076)the Novo Nordisk Foundation(26844).
文摘Membrane-initiated estrogen receptorα(mERα)signaling has been shown to affect bone mass in murine models.However,it remains unknown which cell types mediate the mERα-dependent effects on bone.In this study,we generated a novel mouse model with a conditional C451A mutation in Esr1,which enables selective knockout of the palmitoylation site essential for the membrane localization of ERα(C451A^(f/f)).First,we used Runx2-Cre mice to generate Runx2-C451A^(f/f)mice with conditional inactivation of mERαsignaling in Runx2-expressing osteoblast lineage cells.No significant changes were observed in body weight,weights of estrogen-responsive organs,or serum concentrations of estradiol between female Runx2-C451A^(f/f)and homozygous C451A^(f/f)littermate controls.High-resolution microcomputed tomography analysis showed a consistent decrease in cortical bone mass in the tibia,femur,and vertebra L5 of Runx2-C451A^(f/f)mice and three-point bending analysis of humerus revealed an impaired mechanical bone strength in Runx2-C451A^(f/f)female mice compared to controls.Additionally,primary osteoblast cultures from mice lacking mERαsignaling showed impaired differentiation compared to controls.
基金supported in part by grants from the National Natural Science Foundation of China(No.81673093,No.82170227,No.91649113,No.82470165,No.82000121,No.31771640)the Jiangsu Science and Technology Department(No.SBK20200191)+1 种基金the State Key Laboratory of Radiation Medicine and Protection of Soochow University(No.GZC00201)a project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions.
文摘The crosstalk between megakaryocytic lineage cells and the skeletal system has just begun to be explored but remains largely elusive.Using conditional gene knockout mouse models,we demonstrated that loss of Beclin 1(Becn1),a major regulator of mammalian autophagy,exclusively in the megakaryocytic lineage disrupted autophagy in platelets but did not compromise megakaryopoiesis or the formation and function of platelets.Unexpectedly,conditional Becn1 deletion in male mice led to a remarkable increase in bone mass with improved bone quality,in association with a decrease in sex hormone binding globulin(SHBG)and an increase in free testosterone(FT).In vivo Becn1 overexpression in megakaryocytic lineage-specific cells reduced bone mass and quality,along with an increase in SHBG and a decrease in FT.Transplantation of wild-type bone marrow cells into megakaryocytic lineage Becn1-deficient male mice restored bone mass and normalized SHBG and FT.Furthermore,bilateral orchiectomy of Becn1^(f/f);Pf4-iCre mice,which are crippled with the production of testosterone,resulted in a reduction in bone mass and quality,whereas in vivo overexpression of SHBG,specifically in the liver of Becn1^(f/f);Pf4-iCre mice,decreased FT and reduced bone mass and quality.In addition,metformin treatment,which induces SHBG expression,reduced FT and normalized bone mass in Becn1^(f/f);Pf4-iCre mice.We thus concluded that Becn1 of the megakaryocytic lineage is dispensable locally for platelet hemostasis but limits bone mass by increasing SHBG,which in turn reduces the FT of male mice.Our findings highlight a mechanism by which Becn1 from megakaryocytic lineage cells distally balances bone growth.
基金Project supported by the National Natural Science Foundation of China(22106074)Tianjin Science and Technology Program(23YDTPJC00540,22YJDSS00060)。
文摘Ce-β-Bi_(2)O_(3)/AgI was prepared using solvothermal calcination and in-situ deposition methods.The introduction of Ce can inhibit the conversion of Bi_(2)O_(3)fromβtoαphase at high temperatures,promoting the formation of oxygen vacancies(OVs)in the photocatalyst.OVs can adsorb more dissolved oxygen to promote the formation rate of·O^(-)_(2).Moreover,the interaction between Ce-Bi_(2)O_(3)and AgI results in the formation of Z-scheme heterojunctions,which can broaden the light absorption region,facilitate photogenerated carrier separation and transfer and enhance the ability to produce more active oxygen species(ROS).The morphology,crystal,element distribution and photo-electric chemical properties of the Ce-Bi_(2)O_(3)/AgI were analyzed,and the result shows that the optimal ratio of Ce-Bi_(2)O_(3)/AgI photocatalyst achieves a removal rate of 88.63%(180 min)of tetracycline(TC)(20 mg/L)and 100%(120 min)of methyl orange(MO)(20 mg/L).This work clarified the photocatalytic degradation mechanism,providing a promising avenue for developing photocatalytic composites by rare earth metal doping in environme ntal remediation applications.
基金funded by the National Key Research and Development Program of China(2022ZD0115703)the National Natural Science Foundation of China(32372196)+1 种基金the Beijing Joint Research Program for Germplasm Innovation and New Variety Breeding(G20220628002)National Natural Science Foundation of China(32250410307)。
文摘Non-destructive time-series assessment of chlorophyll content in flag-leaf(FLC)accurately mimics the senescence rate and the identification of genetic loci associated with senescence provides valuable knowledge to improve yield stability under stressed environments.In this study,we employed both unmanned aerial vehicles(UAVs)equipped with red–green–blue(RGB)camera and ground-based SPAD-502 instrument to conduct temporal phenotyping of senescence.A total of 262 recombinant inbred lines derived from the cross of Zhongmai 578/Jimai 22 were evaluated for senescence-related traits across three environments,spanning from heading to 35 d post-anthesis.The manual senescence rate(MSR)was quantified using the FLC and the active accumulated temperature,and UAV derived vegetation index were utilized to assess the stay-green rate(USG)facilitating the identification of senescent and stay-green lines.Results indicated that higher senescence rates significantly impacted grain yield,primarily by influencing thousand-kernel weight,and plant height.Quantitative trait loci(QTL)mapping for FLC,USG,and MSR using the 50K SNP array identified 38 stable loci associated with RGB-based vegetation indices and senescence-related traits:among which 19 loci related to senescence traits from UAV and FLC were consistently detected across at least two growth stages,with nine loci likely representing novel QTL.This study highlights the potential of UAV-based high-throughput phenotyping and phenology in identifying critical loci associated with senescence rates in wheat,validating the relationship between senescence rates and yield-related traits in wheat,offering valuable opportunities for gene discovery and significant applications in breeding programs.
基金supported by the Science Technology Talents Lifting Project of Hunan Province(No.2022TJ-N16)the Natural Science Foundation of Hunan Province(Nos.2024JJ4022,2023JJ30277,2025JJ60382)+3 种基金the China Postdoctoral Fellowship Program(GZC20233205)the Scientifc Research Fund of Hunan Provincial Education Department,China(No.24B0270)the National Natural Science Foundation of China(No.32201646)the Key Project of Jiangxi Provincial Research and Development Program(No.20243BBI91001).
文摘The development of high-performance transition metal sulfide(TMS)/carbon composites to replace conventional graphite anode remains a critical challenge for advancing lithium-ion batteries(LIBs).In this study,a facile self-sacrifice template method is developed to prepare FeS encapsulated into N,S co-doped carbon(FeS/NSC)composite using melamine-cyanuric acid(MCA)supermolecule as a multifunctional template precursor.The function of MCA supermolecule for material synthesis is explored,revealing its special function as a dispersant,dopant and pore-forming agent.Furthermore,the effect of Fe source dosage on the morphology,structure and composition of the final products is explored.The resultant FeS/NSC-0.1(where 0.1 represents the mass of added Fe source)exhibits the most optimal proportion,characterized by a good dispersion status of FeS within the NSC matrix,effective N,S co-doping and ample porosity.Benefiting from these merits,the FeS/NSC-0.1 anode demonstrates significantly improved cycling stability and rate capability when compared to the counterparts.Undoubtedly,this work offers a universal method to produce advanced transition metal sulfide/carbon composite electrodes for energy storage and conversion systems.
基金supported by Natural Science Foundation of Jilin Province(No.SKL202302002)Key Research and Development project of Jilin Provincial Science and Technology Department(No.20210204142YY)+2 种基金The Science and Technology Development Program of Jilin Province(No.2020122256JC)Beijing Kechuang Medical Development Foundation Fund of China(No.KC2023-JX-0186BQ079)Talent Reserve Program(TRP),the First Hospital of Jilin University(No.JDYY-TRP-2024007)。
文摘Prostate cancer(PCa)is characterized by high incidence and propensity for easy metastasis,presenting significant challenges in clinical diagnosis and treatment.Tumor microenvironment(TME)-responsive nanomaterials provide a promising prospect for imaging-guided precision therapy.Considering that tumor-derived alkaline phosphatase(ALP)is over-expressed in metastatic PCa,it makes a great chance to develop a theranostics system with ALP responsive in the TME.Herein,an ALP-responsive aggregationinduced emission luminogens(AIEgens)nanoprobe AMNF self-assembly was designed for enhancing the diagnosis and treatment of metastatic PCa.The nanoprobe exhibited self-aggregation in the presence of ALP resulted in aggregation-induced fluorescence,and enhanced accumulation and prolonged retention period at the tumor site.In terms of detection,the fluorescence(FL)/computed tomography(CT)/magnetic resonance(MR)multi-mode imaging effect of nanoprobe was significantly improved post-aggregation,enabling precise diagnosis through the amalgamation of multiple imaging modes.Enhanced CT/MR imaging can achieve assist preoperative tumor diagnosis,and enhanced FL imaging technology can achieve“intraoperative visual navigation”,showing its potential application value in clinical tumor detection and surgical guidance.In terms of treatment,AMNF showed strong absorption in the near infrared region after aggregation,which improved the photothermal treatment effect.Overall,our work developed an effective aggregation-enhanced theranostic strategy for ALP-related cancers.
文摘The urgent demand for clean energy solutions has intensified the search for advanced storage materials,with rechargeable alkali-ion batteries(AIBs)playing a pivotal role in electrochemical energy storage.Enhancing electrode performance is critical to addressing the increasing need for high-energy and high-power AIBs.Next-generation anode materials face significant challenges,including limited energy storage capacities and complex reaction mechanisms that complicate structural modeling.Sn-based materials have emerged as promising candidates for AIBs due to their inherent advantages.Recent research has increasingly focused on the development of heterojunctions as a strategy to enhance the performance of Sn-based anode materials.Despite significant advances in this field,comprehensive reviews summarizing the latest developments are still sparse.This review provides a detailed overview of recent progress in Sn-based heterojunction-type anode materials.It begins with an explanation of the concept of heterojunctions,including their fabrication,characterization,and classification.Cutting-edge research on Sn-based heterojunction-type anodes for AIBs is highlighted.Finally,the review summarizes the latest advancements in heterojunction technology and discusses future directions for research and development in this area.
文摘The study on sand body connectivity and distribution patterns is of great significance for well emplacement and injection-production pattern analysis in the A oilfield of the Weixi?nan Sag currently at a pre-development stage.Based on the current drilling data,seismic data,and fault development characteristics,this study investigates the connectivity,geometric morphology,planar distribution,and vertical evolution of composite sand bodies(multi-stage superimposed channel sand bodies)within the fault block using seismic forward and inversion modeling.The El3I oil layer group in the third member of the Liushagang Formation is developed in the fan delta-front sub-facies,which mainly consists of subaqueous distributary channels.The thickness of single-stage subaqueous distributary channel sand bodies ranges from 2 to 6 m,and the width of composite channel sand bodies varies from 50 to 100 m.Under the long-term transgression background,the subaqueous distributary channels in the El3I oil layer group are relatively narrow,forming superimposed and continuous composite channel sand bodies through lateral migration and vertical stacking.The long-term base-level cycles control the width of subaqueous distributary channels,while the mid-term base-level cycles control the thickness of these channels.The subaqueous distributary channels developed during the late stage of mid-term base-level fall are thicker than those formed during the early stage.Accordingly,quantitative relationships between channel thickness and width are established for the early and late stages of mid-term base-level fall,to finely depict the evolution patterns of channel sand body geometry and stacking styles across different stages.These findings provide important guidance for accurately predicting the planar distribution and channel width of composite subaqueous distributary channels at different stages of the mid-term baselevel cycles.
基金supported by the National Key R&D Program of China(No.2022YFB3804100)the National Natural Science Foundation of China(No.52231005)+1 种基金the Jiangsu Provincial Key R&D Program(No.BE2021088)the Start-up Research Fund of Southeast University(No.RF1028623113).
文摘Longitudinal magnetic field annealing is utilized for modifying the magnetic anisotropy and enhancing the magnetic softness of Fe_(75)Co_(8)(B_(10)Si_(3)C_(3)P_(1))_(1-x)/_(17)Cux(x=0.5,0.75,1,1.25)nanocrystalline alloys.All of the magnetic field-annealed nanocrystalline alloys with Cu content more than 0.5 at.%exhibit significantly improved soft-magnetic properties,including high saturation magnetic flux density up to 1.87 T,effective permeability of 13,000-16,000 under the condition of 1 A/m and 1 kHz,coercivity as low as 1.6 A/m,and core loss of 0.11-0.45 W/kg under the condition of 1.0 T and 50 Hz.The application of a magnetic field promotes the nucleation and inhibits the growth of grains,leading to an increase in the number density of nanocrystals and the crystalline volume fraction,and a reduction in the grain size.The magnetic field annealing reduces the effective magneto-crystalline anisotropy energy to 2-4 J/m^(3),and induces longitudinal magnetic anisotropy with anisotropy energy density of 400-900 J/m^(3)which shows dependence on the crystalline volume fraction.The field-induced magnetic anisotropy dominates over the random local magnetic anisotropies,and results in the formation of regular magnetic domains aligned longitudinally,pinning-free domain wall displacement,and thus enhanced soft-magnetic properties.
基金supported by the National Natural Science Foundation of China (Nos.52374064,51974347,52474072)the Shandong Provincial Universities Youth Innovation and Technology Support Program (2022KJ065)。
文摘Injection-production coupling(IPC) technology holds substantial potential for boosting oil recovery and enhancing economic efficiency.Despite this potential,discussion on gas injection coupling,especially in relation to microscopic mechanisms,remains relatively sparse.This study utilizes microscopic visualization experiments to investigate the mechanisms of residual oil mobilization under various IPC scenarios,complemented by mechanical analysis at different stages.The research quantitatively assesses the degree of microscopic oil recovery and the distribution of residual oil across different injection-production methods.Findings reveal that during the initial phase of continuous gas injection(CGI),the process closely mimics miscible displacement,gradually transitioning to immiscible displacement as CO_(2)extraction progresses.Compared to CGI,the asynchronous injection-production(AIP) method improved the microscopic oil recovery rate by 6.58%.This enhancement is mainly attributed to significant variations in the pressure field in the AIP method,which facilitate the mobilization of columnar and porous re sidual oil.Furthermo re,the synchronous cycle injection(SCI) method increased microscopic oil recovery by 13.77% and 7.19% compared to CGI and AIP,respectively.In the SCI method,membrane oil displays filame ntary and Karman vo rtex street flow patterns.The dissolved and expanded crude oil te nds to accumulate and grow at the oil-solid interface due to adhesive forces,thereby reducing migration resistance.The study findings provide a theoretical foundation for improving oil recovery in lowpermeability reservoirs.
基金financial support from the National Natural Science Foundation of China(No.52274372)the National Key Research and Development Program of China(No.2021YFB3702404).
文摘A martensitic initial microstructure before hot forming was prepared by direct quenching after hot rolling of the hot formed steel and the effect of such initial microstructure on mechanical properties of steel was analyzed. The process of direct quenching after hot rolling which replaced the steps of coiling and cold rolling was termed as compact process. As the temperature before direct quenching falls within the non-recrystallization range, the deformed austenite grains exhibit flattened morphology along the hot rolling direction, and the high-density dislocations and significant strain energy in deformed austenite are inherited by directly quenched martensite. Moreover, due to promotion of austenite nucleation and subsequent recrystallization during the reverse transformation process in hot forming, both reversed austenite grains and martensite laths are significantly refined. Compared to the conventional process with an initial microstructure consisting of fully recrystallized ferrite and cementite, the compact process reduces average prior austenite grain sizes from 12.5 to 5.5 μm and martensite lath widths from 202 to 123 nm. Additionally, the compact process results in a higher density of dislocations in test steel, leading to maximum yield strength (1294 MPa) and ultimate tensile strength (2266 MPa). Compared to conventional process, this compact process significantly improves the mechanical properties of the hot formed steels while simplifying the production.
基金financially supported by the National Natural Science Foundation of China(Nos.22479102,22001078)the Guangdong Talent Program(No.2023TQ07L822)+1 种基金the Guangdong Basic and Applied Basic Research Foundation(No.2024A1515011716)the startup funding of Songshan Lake Materials Laboratory(No.Y1D1031H311)。
文摘Thiol-ene click polymerization has become an effective synthetic tool for constructing diverse sulfurcontaining polymers with advanced functions.However,the polymerization of internal alkene and thiol has been rarely used to prepare functional polymers because of large steric hindrance and relatively weak reactivity.In this work,a base-catalyzed click polymerization of thiols and internal olefins was successfully established in air.Notably,the polymerization went smoothly in halogen-containing solvent even without any catalyst via a radical step-growth polymerization.The polymerization enjoys excellent monomer applicability,which affords 16 well-defined polythioethers in high yields(up to 99%)with high molecular weights(Mwup to 19,600),good thermal stability(Td,5%up to 326℃),broadly regulated glass transition temperatures(-24~95℃),and unconventional fluorescence.Via a simple solvent regulation strategy,the vanillin-derived polythioether could be used as a turn-off fluorescence probe for Fe3+ions in DMF/H2O and a turn-on probe for Ag+ions in THF,with low detection limits of 9.15×10^(-7)mol/L and 4.60×10^(-7)mol/L,respectively.Additionally,the detection of Ag+presented a transformation from a clear solution to an emulsion,expanding the application prospects through observing colorimetric and fluorescent dual signals.Thus,this work not only holds significance in establishing an efficient polymerization,but also provides a strategy to prepare sensitive fluorescent probes for multiple metal ions.
文摘Siberian taimen Hucho taimen(Pallas,1773)is a broadly distributed and popular sport fish with high economic value.However,low abundance and hard-to-reach habitat make the Siberian taimen a relatively understudied species.Here we describe the morphological variability of two size groups of Siberian taimen juveniles from the eastern(Amur River basin)and western(Kama River basin)parts of the species distribution.The largest morphological differentiation of Siberian taimen juveniles was observed at the inter-basin level.In the Amur River basin,Siberian taimen juveniles also differed morphologically even at sites located at a distance of 20 km from each other,which may be explained by a small home-range inhabitation of juveniles leading to the formation of their morphotype determined by local environmental conditions.The pattern of allometry varies in taimen from different rivers,which could be related to the ontogenetic shift of ecological niches and the level of heterogeneity of the river environment.
基金supported by the National Key Research and Development Program of China(No.2022YFA1602200)the National Natural Science Foundation of China(Nos.12341501 and 12405174)the Hefei Comprehensive National Science Center for the strong support on the STCF key technology research project.
文摘Electron-positron colliders operating in the GeV center-of-mass range,or tau-charm energy region,have been proved to enable competitive frontier research due to several unique features.With the progress of high-energy physics in the last two decades,a new-generation Tau-Charm factory,called the Super Tau-Charm Facility(STCF),has been actively promoted by the particle physics community in China.STCF has the potential to address fundamental questions such as the essence of color confinement and the matter-antimatter asymmetry within the next decades.The main design goals of the STCF are a center-of-mass energy ranging from 2 to 7 GeV and a luminosity surpassing 5×10^(34)cm^(−2)s^(−1)that is optimized at a center-of-mass energy of 4 GeV,which is approximately 50 times that of the currently operating Tau-Charm factory-BEPCII.The STCF accelerator has two main parts:a double-ring collider with a crab-waist collision scheme and an injector that provides top-up injections for both electron and positron beams.As a typical third-generation electron-positron circular collider,the STCF accelerator faces many challenges in both accelerator physics and technology.In this paper,the conceptual design of the STCF accelerator complex is presented,including the ongoing efforts and plans for technological research and develop-ment,as well as the required infrastructure.The STCF project aims to secure support from the Chinese central government for its construction during the 15th Five-Year Plan(2026-2030).
基金funded by the National Natural Science Foundation of China(32272186)the Beijing Natural Science Foundation,China(6242031)+5 种基金the Basal Research Fund of the Chinese Academy of Agricultural Sciences(CAAS)(S2022QH04)the National Key R&D Program of China(2022YFD1201500)the Young Elite Scientists Sponsorship Program by China Association for Science and Technology(YESS,2020QNRC001)the Modern Cold and Drought Characteristic Agricultural Seed Industry Research Project-2025,Gansu Province,China(ZYGG-2025-8)the Nanfan Special Project,CAAS(YBXM2303)the Science and Technology Innovation Program of CAAS。
文摘Black point is a black discoloration of the grain embryo that reduces the grain quality and commodity grade.Identifying the underlying genetic loci can facilitate the improvement of black point resistance in wheat.Here,262 recombinant inbred lines(RILs)from the cross of Zhongmai 578/Jimai 22 were evaluated for their black point reactions in fve environments.A high-density genetic linkage map of the RIL population was constructed with the wheat 50K single nucleotide polymorphism(SNP)array.Six stable QTLs for black point resistance were detected,QBp.caas-2A,QBp.caas-2B1,QBp.caas-2B2,QBp.caas-2D,QBp.caas-3A,and QBp.caas-5B,which explained 2.1-28.8%of the phenotypic variances.The resistance alleles of QBp.caas-2B1 and QBp.caas-2B2 were contributed by Zhongmai 578 while the others were from Jimai 22.QBp.caas-2B2,QBp.caas-2D and QBp.caas-3A overlapped with previously reported loci,whereas QBp.caas-2A,QBp.caas-2B1 and QBp.caas-5B are likely to be new.Five kompetitive allele-specifc PCR(KASP)markers,Kasp_2A_BP,Kasp_2B1_BP,Kasp_2B2_BP,Kasp_3A_BP,and Kasp_5B_BP,were validated in a natural population of 165 cultivars.The fndings of this study provide useful QTLs and molecular markers for the improvement of black point resistance in wheat through marker-assisted breeding.
基金financially supported by the Natural Science Foundation of Shanxi Province(No.202203021221134)。
文摘Antibiotics are crucial medications for preventing and treating bacterial infections.However,due to their inherent resistance to degradation,they are also a major component of water pollutants.Semiconductor photocatalysis is considered to be an important green technology for sewage treatment.In this study,BiVO_(4)/Cd S Z-type heterojunction was synthesized and applied in the photocatalytic degradation of tetracycline hydrochloride(TCH).The Z-type heterojunction not only facilitates the separation of photogenerated charges,but also preserves photogenerated electrons with strong reduction capability and photogenerated holes with high oxidation capability.Following visible light irradiation for 90 min,the efficiency of BiVO_(4)/Cd S photocatalytic degradation of TCH reached 93.1%.Moreover,BiVO_(4)/Cd S demonstrates notable degradation efficacy toward other quinolone antibiotics.Free radical trapping experiments and EPR test results suggest that superoxide radicals,hydroxyl radicals,photogenerated electrons,and holes serve as the primary active species in the photocatalytic degradation process of tetracycline hydrochloride.This study offers valuable insights into the development of Z-type heterojunction photocatalysts for the efficient degradation of tetracycline hydrochloride.
