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Heparan sulfate proteoglycans as possible diagnostic molecular tools with therapeutic potential in Alzheimer′s disease 被引量:1
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作者 Iván Fernández-Vega laura lorente-gea +1 位作者 Carla Martín Luis M.Quirós 《Neural Regeneration Research》 SCIE CAS CSCD 2021年第7期1404-1405,共2页
Importance of dementia and Alzheimer's disease(AD): On Earth, there is a "country" that we call Dementia with around 50 million inhabitants and an estimated global economic cost of US $1 trillion(Wimo et... Importance of dementia and Alzheimer's disease(AD): On Earth, there is a "country" that we call Dementia with around 50 million inhabitants and an estimated global economic cost of US $1 trillion(Wimo et al., 2017).AD may contribute to 60–70% of cases, with other major forms of dementia being vascular dementia, dementia with Lewy bodies and a group of diseases that contribute to frontotemporal dementia.However, the boundaries between different forms of dementia are indistinct and mixed forms often co-exist, which are only confirmed after postmortem neuropathological studies(Fernandez-Vega et al., 2015). 展开更多
关键词 al. DISEASES ALZHEIMER
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Heparan sulfate proteoglycans and heparanases in Alzheimer's disease:current outlook and potential therapeutic targets 被引量:2
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作者 laura lorente-gea Beatriz García +2 位作者 Carla Martín Luis M.Quirós Iván Fernández-Vega 《Neural Regeneration Research》 SCIE CAS CSCD 2017年第6期914-915,共2页
Relevance of Alzheimer’s disease(AD):AD is one of the greatest health-care challenges of the 21^st century.It is known to be the most common neurodegenerative disease and,in the United States,the sixth most common... Relevance of Alzheimer’s disease(AD):AD is one of the greatest health-care challenges of the 21^st century.It is known to be the most common neurodegenerative disease and,in the United States,the sixth most common cause of death. 展开更多
关键词 outlook amyloid pathogenesis prion greatest sixth gression challenges neuronal brains
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