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中年肝硬化患者自我感受负担与家庭功能的相关性分析 被引量:20
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作者 梁首勤 李翔 +4 位作者 高飞 潘寒寒 靳秀 颜萍平 王洁 《护士进修杂志》 2019年第11期999-1001,共3页
目的探索中年肝硬化患者自我感受负担与其家庭功能的相关性。方法采用自我感受负担量表、中文版家庭功能评定量表,对2016年2月-2017年12月河南省人民医院就诊的100例中年肝硬化患者进行调查。结果中年肝硬化患者的自我感受负担总分为(33... 目的探索中年肝硬化患者自我感受负担与其家庭功能的相关性。方法采用自我感受负担量表、中文版家庭功能评定量表,对2016年2月-2017年12月河南省人民医院就诊的100例中年肝硬化患者进行调查。结果中年肝硬化患者的自我感受负担总分为(33.42±6.37)分,处于中度水平,各维度得分由高到底依次为:身体负担、情感负担、经济负担;家庭功能得分为(2.15±0.51)分,各维度由高到低依次为:问题解决、情感反应、角色、情感介入、行为控制、沟通。患者自我感受负担与家庭功能水平呈正相关(r=0.507,P<0.01)。结论中年肝硬化患者自我感受负担与其家庭功能相关。医务工作者应关注家庭功能中问题解决、情感和角色方面的功能,以改善中年肝硬化患者自我感受负担水平。 展开更多
关键词 肝硬化 自我感受负担 家庭功能 护理
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学分制下课程体系建设中存在的问题探讨--以过程装备与控制工程专业为例
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作者 张思 李美求 +1 位作者 李翔 黄天成 《中国教育技术装备》 2019年第22期100-102,共3页
过程装备与控制工程是一个多类学科交叉融合的专业。在高校人才培养过程中,在学分制背景下建立的专业课程体系更能激发学生的学习热情,提高学习效率。分析在学分制背景下,长江大学过程装备专业在课程体系建设过程中存在的问题,给出相应... 过程装备与控制工程是一个多类学科交叉融合的专业。在高校人才培养过程中,在学分制背景下建立的专业课程体系更能激发学生的学习热情,提高学习效率。分析在学分制背景下,长江大学过程装备专业在课程体系建设过程中存在的问题,给出相应措施,提高学分制下学生学习效率和人才培养质量。 展开更多
关键词 学分制 课程体系 过程装备与控制工程 网络学习资源
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从日常磨课到课例研究:问题与路径 被引量:1
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作者 王思萱 冯茹 +1 位作者 李响 崔亚丽 《吉林省教育学院学报》 2020年第6期73-76,共4页
课例研究俗称"磨课",是校本教研的重要方式之一,对于理论与实践的结合有着重要意义。课例研究是教师作为研究者基于课堂教学中的实际问题,汲取教师自身及集体的反思,实现教师教学观念和教学行为的转变,促进教师的专业成长与... 课例研究俗称"磨课",是校本教研的重要方式之一,对于理论与实践的结合有着重要意义。课例研究是教师作为研究者基于课堂教学中的实际问题,汲取教师自身及集体的反思,实现教师教学观念和教学行为的转变,促进教师的专业成长与发展。但是一线教师在日常磨课中缺少对课例的研究,因而存在研究主题不聚焦、文本解读不深入、学情分析不深刻、对话主体不对等、教师反思性不足等问题。因此,需要加强教师个人专业储备并提高教学反思能力,建立教师群体学习共同体,加强学校课例库建设。 展开更多
关键词 磨课 课例研究 校本教研
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miR-23a-3p通过调控SIRT1/FOXO1通路影响NAFLD小鼠肝脏脂质代谢的研究 被引量:4
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作者 孙雪莲 杨佳楠 +4 位作者 姜同连 朱福彬 于闪闪 李响 李洪志 《中国病理生理杂志》 CAS CSCD 北大核心 2022年第12期2175-2182,共8页
目的:探究微小RNA-23a-3p(miR-23a-3p)对非酒精性脂肪性肝病(NAFLD)小鼠肝脏脂质代谢的影响及沉默信息调节因子1(SIRT1)/叉头框蛋白O1(FOXO1)通路在其中的作用。方法:qPCR检测miR-23a-3p在脂肪肝细胞模型及NAFLD小鼠模型中的表达情况。... 目的:探究微小RNA-23a-3p(miR-23a-3p)对非酒精性脂肪性肝病(NAFLD)小鼠肝脏脂质代谢的影响及沉默信息调节因子1(SIRT1)/叉头框蛋白O1(FOXO1)通路在其中的作用。方法:qPCR检测miR-23a-3p在脂肪肝细胞模型及NAFLD小鼠模型中的表达情况。高脂饮食(HFD)诱导miR-23a-3p基因敲除(miR-23a KO)小鼠,设置野生型(WT)C57BL/6小鼠正常饮食(ND)组和HFD组及miR-23a KO小鼠ND组和HFD组,每组10只,HFD组小鼠均接受HFD 12周。对各组小鼠体重和肝脏指数进行统计;HE染色观察肝组织病理损伤变化;油红O染色检测肝脏组织脂质蓄积程度;生化分析检测血清中总胆固醇(TC)、甘油三脂(TG)、丙氨酸转氨酶(AST)、天冬氨酸转氨酶(ALT)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)水平;qPCR检测肝脏脂代谢相关基因Srebp1、Fas、Pparγ、Pparα、Acc1和Cpt1的mRNA水平;双萤光素酶报告基因实验分析miR-23a-3p和SIRT1基因的靶向关系;Western blot检测AMP活化蛋白激酶(AMPK)、SIRT1、过氧化物酶体增殖物激活受体α(PPARα)及FOXO1蛋白的表达。结果:与对照组比较,脂肪肝细胞模型、动物模型及db/db小鼠肝组织中miR-23a-3p表达显著升高。与HFD(WT)组比较,HFD(miR-23a KO)组体重和肝脏脏器系数显著降低;HE和油红O染色结果显示,HFD(miR-23a KO)组肝脏脂肪蓄积减轻;血清TC、TG、AST和LDL-C水平显著降低(P<0.05),HDL-C水平显著升高(P<0.05);脂代谢相关基因Srebp1、Fas、Pparγ和Acc1的mRNA水平显著降低(P<0.05),Cpt1的mRNA水平显著升高(P<0.05)。双萤光素酶报告基因实验证明miR-23a-3p可以靶定SIRT1基因。Western blot结果显示,与HFD(WT)组比较,HFD(miR-23aKO)组SIRT1和PPARα表达显著增加(P<0.05),p-AMPK/AMPK比值显著升高(P<0.05),AcFOXO1/FOXO1比值显著降低(P<0.01)。结论:miR-23a-3p的缺失能够减轻HFD诱导的NAFLD小鼠肝脏脂质蓄积,改善肝脏的生理功能。miR-23a-3p的作用可能是通过靶定SIRT1基因而使FOXO1去乙酰化,进而影响肝脏脂质代谢。 展开更多
关键词 微小RNA-23a-3p 非酒精性脂肪性肝病 SIRT1/FOXO1信号通路 脂质代谢
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ACTIVATION ENERGY OF DESORPTION OF DIBENZOFURAN ON ACTIVATED CARBONS 被引量:1
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作者 lixiang LIZhong +1 位作者 XIHongxia LUOLingai 《Chinese Journal of Reactive Polymers》 2004年第1期49-56,共8页
Three kinds of commercial activated carbons, such as Norit RB1, Monolith and Chemviron activated carbons, were used as adsorbents for adsorption of dibenzofuran. The average pore size and specific surface area of thes... Three kinds of commercial activated carbons, such as Norit RB1, Monolith and Chemviron activated carbons, were used as adsorbents for adsorption of dibenzofuran. The average pore size and specific surface area of these activated carbons were measured. Temperature Programmed Desorption (TPD) experiments were conducted to measure the TPD curves of dibenzofuran on the activated carbons, and then the activation energy for desorption of dibenzofuran on the activated carbons was estimated. The results showed that the Chemviron and the Norit RB1 activated carbon maintained higher specific surface area and larger micropore pore volume in comparison with the Monolith activated carbon, and the activation energy for the desorption of dibenzofuran on these two activated carbons was higher than that on the Monolith activated carbon. The smaller the pore of the activated carbon was, the higher the activated energy of dibenzofuran desorption was. 展开更多
关键词 TPD DIBENZOFURAN Desorption activation energy.
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A Study on Heat Resistance and Initial Characterization of Protease Inhibitors in Porcine Colostrum
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作者 ZHOUQi HERui-guo +4 位作者 YUANQian-hua lixiang LIAOSheng-rong ZHOUWu KONGNi-jia 《Agricultural Sciences in China》 CAS CSCD 2003年第9期1048-1053,共6页
Porcine colostrum was separated into the acid soluble fraction (SF) and casein fraction (CF) by acidifying followed by centrifuge. SF was further separated by liquid chromatography and anisotropic membrane filtration... Porcine colostrum was separated into the acid soluble fraction (SF) and casein fraction (CF) by acidifying followed by centrifuge. SF was further separated by liquid chromatography and anisotropic membrane filtration. Capacities of the SF or CF of porcine colostrum, to inhibit trypsin and chymotrypsin activity and to inhibit the epidermal growth factor (EGF) degradation in pig small intestinal contents, were determined under different heat treatments. The study showed that trypsin inhibitors in porcine colostrum survived heat treatments of 100℃ water bath for up to 10 min, but exposure to boiling water bath for 30 min significantly decreased the inhibitory activity. Compared with the trypsin inhibitors, the chymotrypsin inhibitors were more heat sensitive. SF was more heat sensitive than CF. Separation of the SF of porcine colostrum by liquid chromatography and anisotropic membrane filtration revealed that the porcine colostrum protease inhibitors, those had the capacity to inhibit the trypsin chymotrypsin activity and enhanced the stability of EGF in the gastrointestinal(GI) lumen of weaned pigs, existed mainly in SF, milk derived, were a group of heat labile small proteins with molecular weight of 10 00050 000. 展开更多
关键词 Porcine colostrum Protease inhibitors Heat resistance Molecular weight Inhibitory capa city
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A Study on the Inhibitory Potency of Protease Inhibitorsin Porcine Colostrum
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作者 ZHOUQi HERui-guo +4 位作者 lixiang LIAOSheng-rong ZHOUWu DUJin-ping KONGNi-jia 《Agricultural Sciences in China》 CAS CSCD 2003年第7期809-814,共6页
Porcine colostrum and milk were separated into the acid-soluble fraction(SF)and casein fraction(CF)by centrifuge. Trypsin and chymotrypsin inhibitory capacity in porcine colostrum, milk and their components were deter... Porcine colostrum and milk were separated into the acid-soluble fraction(SF)and casein fraction(CF)by centrifuge. Trypsin and chymotrypsin inhibitory capacity in porcine colostrum, milk and their components were determined by incubating bovine trypsin or chymotrypsin in a medium. The inhibition of insulin-like growth factor I(IGF-I)and epidermal growth factor(EGF)degradation in pig small intestinal contents by porcine colostrum was measured by incubating iodinated IGF-I or EGF. Degradation of labeled IGF-I or EGF was determined by monitoring the generation of radioactivity soluble in 30% trichloroacetic acid(TCA). The results showed that porcine colostrum had high levels of trypsin and chymotrypsin inhibitory activity and increased the stability of IGF-I and EGF in pig intestinal contents. The SF was higher in inhibitory potency than CF. The present study revealed that the protease inhibitors in porcine colostrum, milk-derived and colostrum-specific, existed mainly in SF. 展开更多
关键词 Porcine colostrum Protease inhibitors Inhibitory capacity Growth factors
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Globally Asymptotic Stability of Equilibrium of a Dynamical Model with Infinite Delay
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作者 lixiang WENGPei-xuan 《Chinese Quarterly Journal of Mathematics》 CSCD 2003年第2期121-128,共8页
By using a criterion for asymptotic stability in Banach space BC, a group of sufficient condi-tioas for a dynamical model with infinite delay which is derived from hematology were obtained, which refined the result in... By using a criterion for asymptotic stability in Banach space BC, a group of sufficient condi-tioas for a dynamical model with infinite delay which is derived from hematology were obtained, which refined the result in the reference [ 10] got by the second author herself. 展开更多
关键词 integro-differential equation infinite delay EQUILIBRIUM globally asymptotic stability
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An Optimal Flow Control Algorithm for Real-time Traffic over the Internet
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作者 张敬辕 Xie +2 位作者 Jianying Liu lixiang 《High Technology Letters》 EI CAS 2001年第4期46-49,共4页
According to the Wide Area Network model and queue dynamics in the router, the authors formulate the Internet flow control as a constrained convex programming problem, where the objective is to maximize the total util... According to the Wide Area Network model and queue dynamics in the router, the authors formulate the Internet flow control as a constrained convex programming problem, where the objective is to maximize the total utility and minimize transmission delay and delay jitter of all sources over their transmission rates. Based on this formulation, flow control can be solved by means of a gradient projection algorithm with properly rate iterations. The main difficulty facing the realization of the iteration algorithm is the distributed computation of the congestion measure. Fortunately, Explicit Congestion Notification (ECN) is likely to be used to improving the performance of TCP in the near future. By using ECN, it is possible to realize the iteration algorithm in IP networks. The algorithm is divided into two parts, algorithms in the router and the source. The main advantage of the scheme is its fast convergence ability and robustness, but small queue length fluctuation is unavoidable when the number of users increases. 展开更多
关键词 Flow control Explicit congestion notification DELAY Donvex optimization
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吉林省博物院藏中华苏维埃共和国时期残废证书
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作者 刘派 李想 《文物春秋》 2022年第4期79-83,共5页
吉林省博物院藏有一件中华苏维埃共和国时期发放的残废证书,是中国工农红军抚恤工作的重要见证物,可与中华苏维埃共和国时期的相关文献资料互相印证,具有重要的历史价值。
关键词 残废证书 中华苏维埃共和国 抚恤制度
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Effects of Harvesting Machinery on Maize Growth and Yield
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作者 lixiang KEXiheng +2 位作者 CAOShanchao ZHANGYangli ZENGQiao 《外文科技期刊数据库(文摘版)自然科学》 2022年第3期103-107,共5页
Objective: in order to improve the straw returning measures, improve the returning quality and ensure the grain yield. Methods: based on years of practice, four treatments were set up to compare the effects of wheat h... Objective: in order to improve the straw returning measures, improve the returning quality and ensure the grain yield. Methods: based on years of practice, four treatments were set up to compare the effects of wheat harvesting machinery and pre-sowing operation on emergence rate, plant height and yield. Results: it was found that the harvesting machinery had a great impact on the growth and yield of maize. Under the condition of consistent operation before sowing, the emergence rate of maize with Yangma harvester increased by 8.8% and 13.5% as compared with that with Rivo harvester, and the maize yield increased by 197,143 kg. Conclusion: improving straw returning measures (including the selection of agricultural machinery) is an important method to improve the quality of straw returning, reduce the input of chemical fertilizers, and improve the quality and efficiency of crops. 展开更多
关键词 straw returning to field harvesting machinery pre-broadcast homework emergence rate yield
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Study on the Value and Detection Rate of AEEG in Epilepsy Monitoring
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作者 lixiang 《外文科技期刊数据库(文摘版)医药卫生》 2022年第7期195-199,共5页
Objective: to analyze the value and detection rate of dynamic video electroencephalogram in epilepsy monitoring. Methods: the study was carried out from November 2019 to October 2021. Seventy patients with epilepsy ad... Objective: to analyze the value and detection rate of dynamic video electroencephalogram in epilepsy monitoring. Methods: the study was carried out from November 2019 to October 2021. Seventy patients with epilepsy admitted to our hospital were included in the study. All patients were examined by routine electroencephalogram and dynamic video electroencephalogram, and the results were comprehensively evaluated. Results: clinical seizures and abnormal discharges were detected in 31.4% and 98.6% of the patients in the observation group and 5.7% and 55.7% of the patients in the control group. The detection rates of clinical seizures and abnormal discharges in the observation group were higher than those in the control group (P < 0.05). The detection rate of mild seizure in the observation group was lower than that in the control group, and the positive detection rate of moderate seizure, severe seizure and epilepsy in the observation group was higher than that in the control group (P < 0.05). Dynamic video-electroencephalogram confirmed that the epileptic seizure types were facial tonic-clonic seizure, absence seizure, myoclonic seizure, tonic seizure and dystonic seizure, accounting for 28.6%, 21.4%, 15.7%, 21.4% and 12.9% respectively;In the examination of the onset position of epilepsy by dynamic video-electroencephalogram, 40 cases of onset position were detected, and the others were not clear. 8 cases were found in frontal region, 13 cases in temporal region, 10 cases in temporal frontal region, 5 cases in occipital-temporal posterior region and 4 cases in frontal center. Conclusion: compared with routine ECG, the detection rate of dynamic video electroencephalogram is higher in epilepsy detection. It can also clarify the type and initial location of epileptic seizures and the severity of epilepsy, which can provide a basis for clinical diagnosis and treatment of the disease. 展开更多
关键词 EPILEPSY dynamic video electroencephalogram monitoring value detection rate
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Hidden Dangers and Prevention Measures of the Construction Quality of Heating Pipe Network Project
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作者 lixiang 《外文科技期刊数据库(文摘版)工程技术》 2022年第9期129-132,共4页
The sustainable development of Chinas social economy, the heating pipe network project has also had a great development. At present, the society gives positive encouragement and advocacy to the sustainable development... The sustainable development of Chinas social economy, the heating pipe network project has also had a great development. At present, the society gives positive encouragement and advocacy to the sustainable development of the project, and takes energy conservation and emission reduction as a very important task at present. Environmental protection has also become the primary factor of project construction. Central heating has been gradually adopted by construction workers in the heat network, mainly because central heating can greatly reduce the cost of the project. But if there is a problem in a node in the heat network, it will lead to a large area of the heat network without heating phenomenon. Therefore, due to the complex pipe network, the quality danger of heating pipe network is easy to occur in the construction process. Strengthening the construction technology is an important basis to ensure the quality. 展开更多
关键词 heating pipe network engineering construction quality hidden dangers prevention and control measu
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Discussion on the Application Value of Rehabilitation Nursing in Pediatric Severe Viral Encephalitis Nursing
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作者 lixiang 《外文科技期刊数据库(文摘版)医药卫生》 2022年第12期041-044,共4页
Objective: to study the degree to which children with severe viral encephalitis can obtain rehabilitation nursing services during admission treatment, and to study the clinical value of rehabilitation nursing. Methods... Objective: to study the degree to which children with severe viral encephalitis can obtain rehabilitation nursing services during admission treatment, and to study the clinical value of rehabilitation nursing. Methods: choose in February 2019 to February 2022 three years into our treatment of severe viral encephalitis children as a research sample, into the scope of the children randomly processing, part of children into the control group to accept routine nursing services, the other part into the observation group of rehabilitation care services, collect children under the influence of two different nursing services, evaluate rehabilitation nursing services, the actual effect of application in children with severe viral encephalitis. Results: children receiving rehabilitation care were significantly different from the usual care services in terms of symptom improvement time and motor function score (P < 0.05), and the collected data were statistically significant. Conclusion: children with severe viral encephalitis limbs, consciousness, nerve aspects is affected by the serious, daily life and activities, clinical application of rehabilitation care, rehabilitation nursing services can be used in improving clinical symptoms and improve children movement function score plays an important role, so it is worth promoting in clinical practice. 展开更多
关键词 rehabilitation and nursing severe viral encephalitis in children nursing services application val
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Discussion on Cause Analysis and Inspection of Elevator Braking Failure
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作者 YAOJin lixiang 《外文科技期刊数据库(文摘版)工程技术》 2022年第7期112-115,共4页
In the process of continuously improving the level of urbanization construction, the level of urban economic development is increasing, which also provides more opportunities for the development of the construction in... In the process of continuously improving the level of urbanization construction, the level of urban economic development is increasing, which also provides more opportunities for the development of the construction industry. Facing the increasingly serious contradiction between people and land, the construction of construction projects needs to develop towards high-rise buildings. In high-rise buildings, elevators can provide many conveniences for peoples lives. The safety and stability of their operation will be closely related to the safety of peoples lives and properties. Therefore, it is necessary to do a good job in the research of elevator braking in order to comprehensively improve the stability of elevator operation. In the following paragraphs, the principle of elevator brake is firstly discussed, then the reasons of elevator brake failure are analyzed, then the main requirements of elevator brake work are studied, and finally the inspection measures of elevator brake failure are comprehensively analyzed for reference. 展开更多
关键词 ELEVATOR brakes failure cause inspection countermeasures
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宁夏灵武市枣博园景观规划设计
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作者 白红艳 李涛 李翔 《园林》 2018年第12期74-78,共5页
宁夏灵武市世界枣树博览园是以展示枣文化和品种收集为核心,集科普研究、种资收集、旅游观光、休闲娱乐为一体的综合性开放式园区。本文结合宁夏灵武市枣博园景观规划设计实例,从项目的基地概况与分析、设计主题及定位、总体布局、功能... 宁夏灵武市世界枣树博览园是以展示枣文化和品种收集为核心,集科普研究、种资收集、旅游观光、休闲娱乐为一体的综合性开放式园区。本文结合宁夏灵武市枣博园景观规划设计实例,从项目的基地概况与分析、设计主题及定位、总体布局、功能分区及景点规划等方面,对枣博园的景观规划设计进行初步探析,旨在为今后类似的园区景观改造设计提供有益的参考。 展开更多
关键词 枣文化 博览园 品种收集 景观设计
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Analysis on the Relevant Factors and Treatment Countermeasures of Death of Emergency Trauma Patients
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作者 lixiang XUHua XIANGWei 《外文科技期刊数据库(文摘版)医药卫生》 2022年第1期048-051,共4页
Objective: to analyze the related factors of death in emergency trauma patients and the treatment measures, and to provide effective reference for clinical diagnosis and treatment. Methods: 100 cases of trauma patient... Objective: to analyze the related factors of death in emergency trauma patients and the treatment measures, and to provide effective reference for clinical diagnosis and treatment. Methods: 100 cases of trauma patients admitted to our emergency surgery department from 2015 to 2018 were selected for this retrospective analysis, focusing on discussing and analyzing the causes of death cases. Results: among the patients with different causes of injury, the death rate from falling from height was the highest, reaching 85.71%, followed by traffic accidents, with the death rate of 42.86%. Heavy blows, knife wounds and other causes were 40.00%, 20.00% and 20.00% respectively. In terms of the causes of death, craniocerebral injury, traumatic hemorrhagic shock and traumatic asphyxia accounted for 51.85%, 25.93% and 22.22% respectively. Conclusion: in the process of emergency surgical trauma patients' treatment, targeted prevention and treatment must be carried out for the high incidence of death causes, and pre-hospital and in-hospital first aid capabilities must be strengthened, so as to ensure the scientific treatment plan and reduce the mortality rate as far as possible. 展开更多
关键词 death of emergency trauma patients relevant factors treatment measures
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寒地棚室春季番茄套种分蘖洋葱栽培技术 被引量:1
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作者 杨升 李响 +3 位作者 田丽美 王岭 李德泽 张桂芝 《吉林蔬菜》 2020年第1期11-12,共2页
介绍寒地棚室春季番茄套种分蘖洋葱栽培技术,包括品种选择、播种育苗、定植、定植后管理、采收及病虫害防治等关键技术。
关键词 寒地 棚室 番茄 分蘖洋葱 套种
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