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PE、DPMAS、CVVHDF模式治疗乙肝相关慢加亚急性肝衰竭患者的效果对比
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作者 徐炜捷 黄水文 +2 位作者 刘宝荣 刘宁 蓝丽琴 《中国疗养医学》 2024年第9期86-89,共4页
目的探讨血浆置换(PE)、双重血浆分子吸附(DPMAS)、连续性静脉-静脉血液滤过透析(CVVHDF)模式治疗乙肝相关慢加亚急性肝衰竭(HBV-ACLF)患者的效果。方法选取2021年11月至2023年2月于福建医科大学孟超肝胆医院进行治疗的HBV-ACLF患者90例... 目的探讨血浆置换(PE)、双重血浆分子吸附(DPMAS)、连续性静脉-静脉血液滤过透析(CVVHDF)模式治疗乙肝相关慢加亚急性肝衰竭(HBV-ACLF)患者的效果。方法选取2021年11月至2023年2月于福建医科大学孟超肝胆医院进行治疗的HBV-ACLF患者90例,根据治疗方式不同分为PE组,DPMAS组,CVVHDF组,每组均30例。对比三组患者肝功能指标、凝血功能、内毒素(ET)及高迁移率族蛋白B1(HMGB1)水平,随访60 d生存情况。结果治疗后,三组患者总胆红素(TBIL)、谷丙转氨酶(ALT)、谷草转氨酶(AST)、凝血酶原时间(PT)、凝血酶原活动度(PTA)比较,差异有统计学意义(P<0.05);CVVHDF组TBIL、ALT、AST、PT低于DPMAS组及PE组,CVVHDF组PTA高于DPMAS组及PE组(P<0.05);治疗后,三组患者ET、HMGB1比较,差异有统计学意义(P<0.05);CVVHDF组患者ET、HMGB1水平低于DPMAS组及PE组(P<0.05);随访60 d后,CVVHDF组患者生存率高于DPMAS组及PE组(P<0.05)。结论三种人工肝模式均可改善患者的肝功能、凝血功能、ET和HMGB1水平,提高生存率,但采用CVVHDF效果更优。 展开更多
关键词 血浆置换 双重血浆吸附 连续性血液透析滤过 乙肝相关慢加亚急性肝衰竭
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基于分级诊疗的肝病专科医联体建设实践与反思 被引量:6
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作者 杨世达 柯坤宇 +2 位作者 刘宝荣 邓清文 刘文彬 《卫生经济研究》 北大核心 2019年第1期66-68,71,共4页
以福建省肝病专科医联体建设为例,归纳具体实践措施,总结主要成效,从强化基层医疗机构相关专业科室建设、制订特定病种分级诊疗临床标准、发挥互联网技术和大数据平台支撑作用、完善医保政策的引导作用等方面,提出推进专科医联体建设的... 以福建省肝病专科医联体建设为例,归纳具体实践措施,总结主要成效,从强化基层医疗机构相关专业科室建设、制订特定病种分级诊疗临床标准、发挥互联网技术和大数据平台支撑作用、完善医保政策的引导作用等方面,提出推进专科医联体建设的对策建议。 展开更多
关键词 分级诊疗 医联体 肝病专科
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人工肝血浆透析滤过干预启动时间与乙型肝炎相关性慢加急性肝衰竭患者院内预后之间的关联 被引量:8
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作者 林建辉 陈丽霞 +4 位作者 蓝丽琴 刘宝荣 林銮锋 俞晓玲 刘海钰 《中国血液净化》 CSCD 2023年第3期222-227,共6页
目的探索人工肝血浆透析滤过(plasma diafifiltration,PDF)干预启动时间与乙型肝炎相关慢加急性肝衰竭(HBV-related acute-on-chronic liver failure,HBV-ACLF)患者院内预后之间的关联。方法选取2017年01月01日~2021年12月31日确诊HBV-A... 目的探索人工肝血浆透析滤过(plasma diafifiltration,PDF)干预启动时间与乙型肝炎相关慢加急性肝衰竭(HBV-related acute-on-chronic liver failure,HBV-ACLF)患者院内预后之间的关联。方法选取2017年01月01日~2021年12月31日确诊HBV-ACLF的患者,按院内预后分为改善组与未改善组,对2组人口统计学、基线实验室检查及院内预后等通过单因素及多因素Logistic回归分析确立独立影响因素,平滑曲线拟合探索PDF干预启动时间与院内预后的关联。结果共纳入88例患者,改善组60例(68.2%),单因素Logistic回归分析显示PDF干预启动时间(OR=1.03,95%CI:1.01~1.04,P<0.001)、年龄(OR=1.06,95%CI:1.02~1.11,P=0.005)、基线血丙氨酸氨基转移酶(OR=1.00,95%CI:1.00~1.00,P=0.012)、基线合并腹腔感染(OR=3.13,95%CI:1.20~8.14,P=0.019)是可能的影响因素;多因素Logistic回归分析显示PDF干预启动时间(OR=1.04,95%CI:1.02~1.05,P<0.001)、年龄(OR=1.08,95%CI:1.01~1.14,P=0.038)、HBV-ACLF早期(OR=0.13,95%CI:0.02~0.98,P=0.048)是院内不良预后的独立影响因素;PDF干预启动时间与院内不良预后之间可能存在阈值效应;分段回归模型显示最佳阈值为72小时,小于72小时OR=0.75,95%CI:0.53~1.05,P=0.089;大于72小时OR=1.04,95%CI:1.02~1.06,P<0.001。结论PDF干预启动时间与患者院内不良预后之间存在阈值效应,确诊HBV-ACLF后72小时以内完善手术前评估并立即启动PDF干预可能是潜在的临床救治时机之一。 展开更多
关键词 乙型肝炎 慢加急性肝衰竭 人工肝 血浆透析滤过 干预时间
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Tensor Susceptibilities of QCD Vacuum and Parameterized Quark Propagator
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作者 ZHOU Li-Juan MENG Cheng-Ju +2 位作者 PAN Ji-Huan liu bao-rong MA Wei-Xing 《Communications in Theoretical Physics》 SCIE CAS CSCD 2008年第3期717-722,共6页
Based on the parameterized fully dressed quark propagator proposed by us, the tensor susceptibilities of QCD vacuum and quark vacuum condensates are investigated. Our predicted values of the tensor susceptibilities ar... Based on the parameterized fully dressed quark propagator proposed by us, the tensor susceptibilities of QCD vacuum and quark vacuum condensates are investigated. Our predicted values of the tensor susceptibilities are in agreement with those predicted by many other theoretical models with QCD feature. The results also show that the tensor susceptibility of QCD vacuum strongly depends on flavor of quark but not sensitive to variation of quark vacuum condensates. However, the quark vacuum condensate is very sensitive to the change of cut-off-parameter μ^2 of the integration, that is, it depends on the separation point of perturbative and non-perturbative QCD region. The successful predictions clearly indicate the extensive validity of our parameterized fully dressed quark propagator used here. 展开更多
关键词 QCD vacuum tensor susceptibilities quark propagator
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J/ψ and φ Electro-production in Pomeron Exchange Model
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作者 liu bao-rong ZHOU Li-Juan +3 位作者 MA Wei-Xing TAN Zhen-Qiang GU Yun-Ting HE Xiao-Rong 《Communications in Theoretical Physics》 SCIE CAS CSCD 2007年第2X期326-330,共5页
Based on Pomeron exchange model, J/ψ and φ production in electro-proton interaction are investigated with both linear and non-linear Pomeron trajectory. The experimental differential cross sections measured as a fun... Based on Pomeron exchange model, J/ψ and φ production in electro-proton interaction are investigated with both linear and non-linear Pomeron trajectory. The experimental differential cross sections measured as a function of the kinematic variable Q^2,W and t are reproduced successfully in the model. Our conclusions are that the Pomeron exchange model is a successful description of J/ψ and φ electro-productions on the proton, and that the linear trajectory is a good approximation to non-linearity of the Pomeron trajectory. 展开更多
关键词 vector meson electro-production diffractive process Pomeron exchange model
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Searching for Odderon with ^-pp and pp Elastic Scattering at High Energies
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作者 ZHOU Li-Juan liu bao-rong MA Wei-Xing 《Communications in Theoretical Physics》 SCIE CAS CSCD 2007年第3X期519-524,共6页
Based on the assumption that the Pomeron is a sum of Regge multipoles, each of which corresponds to a finite gluon ladder, we suggest a way to search the Odderon by studying the diffractive processes of ^-pp and pp el... Based on the assumption that the Pomeron is a sum of Regge multipoles, each of which corresponds to a finite gluon ladder, we suggest a way to search the Odderon by studying the diffractive processes of ^-pp and pp elastic scattering. From our theoretical calculations and fits to the corresponding experimental data at high energies and all available momentum transfer, we find that the Odderon plays a significant role in the description of differential cross section dσ/ dt in the whole experimental domain. Accordingly, we can claim that the ^-pp and pp diffractive processes at high energies s and moderate momentum transfer t could be a good tool to search for Odderon and to test QCD since the processes are purely non-perturbative QCD phenomena. Therefore, the experimental measurements are urgently demanded. 展开更多
关键词 ODDERON diffractive processes non-perturbative QCD
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φElectro-production in Pomeron Exchange Model
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作者 MA Wei-Xing liu bao-rong +3 位作者 ZHOU Li-Juan TAN Zhen-Qiang HE Xiao-Rong GU Yun-Ting 《Communications in Theoretical Physics》 SCIE CAS CSCD 2005年第2X期329-332,共4页
Based on the Pomeron exchange model, elastic production of φ meson in electron-proton interaction is investigated with both linear and non-linear Pomeron trajectories. The numerical calculations of the differential c... Based on the Pomeron exchange model, elastic production of φ meson in electron-proton interaction is investigated with both linear and non-linear Pomeron trajectories. The numerical calculations of the differential cross section for e + p → e' + p+ φ are performed. The theoretical predictions show that the dependence of the differentialcross section on virtual photon virtuality, Q2, is of moderation, the change of the energy scale parameter so causes moderate effect on the differential cross section, and the linear trajectory is a good approximation to non-linearity of the Pomeron trajectory, in particular, at small momentum transfer region | t |≤ 0.2 GeV2. 展开更多
关键词 φelectro-production Pomeron exchange model
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血浆置换联合连续性血液净化治疗青少年急性肝衰竭的疗效
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作者 林銮锋 林建辉 +2 位作者 刘宝荣 官升灿 卢玲玲 《蛇志》 2019年第4期481-482,488,共3页
目的观察血浆置换联合连续性血液净化治疗青少年急性肝衰竭的短期疗效。方法对2016年5月~2019年5月收治的66例青少年急性肝衰竭患者为本次研究对象,按照随机分配原则将患者分为对照组和实验组各33例,对照组行单一血浆置换治疗,实验组行... 目的观察血浆置换联合连续性血液净化治疗青少年急性肝衰竭的短期疗效。方法对2016年5月~2019年5月收治的66例青少年急性肝衰竭患者为本次研究对象,按照随机分配原则将患者分为对照组和实验组各33例,对照组行单一血浆置换治疗,实验组行血浆置换联合连续性血液净化治疗,观察比较两组患者的治疗效果。结果实验组患者持续性治疗3次后凝血酶原活动度(Prothrombin activity,PTA)、凝血酶原时间(prothrombin time,INR)、谷丙转氨酶(Alanine aminotransferase,ALT)以及总胆红素(total bilirubin,TBIL)等相关生化检测指标、3个疗程后的总有效率(96.97%)均优于对照组,差异有统计学意义(均P<0.05)。结论急性肝衰竭患者血浆置换联合连续性血液净化治疗效果明显优于单一血浆置换治疗。 展开更多
关键词 血浆置换 联合治疗 连续性血液净化 急性肝衰竭 青少年
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