Objective: to observe the efficacy of intense pulsed light (IPL) in the treatment of refractory Demodex blepharitis. Methods: a prospective study was conducted to collect 15 patients with Demodex blepharitis diagnosed...Objective: to observe the efficacy of intense pulsed light (IPL) in the treatment of refractory Demodex blepharitis. Methods: a prospective study was conducted to collect 15 patients with Demodex blepharitis diagnosed in Zigong first people's Hospital from September 2020 to may 2021 and ineffective after treatment with tea tree essential oil for 3 months. They were treated with IPL for 4 times (the first 3 times, with an interval of 2 weeks, and the last time with an interval of 4 weeks). The symptoms and symptoms of patients before and after treatment (2 weeks, 4 weeks, 8 weeks and 12 weeks) were observed changes in the total amount of Demodex and the number of Demodex in different stages. Results: during the 3-month follow-up period, the symptom score and the number of Demodex decreased significantly. Before treatment, at 2 weeks, 4 weeks, 8 weeks and 12 weeks after treatment, the symptom scores were 9.69 ± 2.06, 9.08 ± 2.02, 7.85 ± 2.34, 3.69 ± 2.84 and 3.23 ± 3.19 respectively. The symptoms improved from the 8th week, and the difference was statistically significant compared with that before treatment (P < 0.05);The total amount of Demodex was 17 (11.5, 26.25), 13.5 (11, 18.75), 11.5 (8.5, 16.75), 7 (5.25, 11.25) and 6 (1.75, 7.75) respectively. From the 8th week, the total amount of Demodex was lower than that before treatment (P < 0.05). The number of Demodex decreased mainly in adults (P < 0.05), but there was no significant difference in the number of eggs and larvae (P ≥ 0.05). Conclusion: IPL is an effective method for the treatment of refractory Demodex blepharitis.展开更多
文摘Objective: to observe the efficacy of intense pulsed light (IPL) in the treatment of refractory Demodex blepharitis. Methods: a prospective study was conducted to collect 15 patients with Demodex blepharitis diagnosed in Zigong first people's Hospital from September 2020 to may 2021 and ineffective after treatment with tea tree essential oil for 3 months. They were treated with IPL for 4 times (the first 3 times, with an interval of 2 weeks, and the last time with an interval of 4 weeks). The symptoms and symptoms of patients before and after treatment (2 weeks, 4 weeks, 8 weeks and 12 weeks) were observed changes in the total amount of Demodex and the number of Demodex in different stages. Results: during the 3-month follow-up period, the symptom score and the number of Demodex decreased significantly. Before treatment, at 2 weeks, 4 weeks, 8 weeks and 12 weeks after treatment, the symptom scores were 9.69 ± 2.06, 9.08 ± 2.02, 7.85 ± 2.34, 3.69 ± 2.84 and 3.23 ± 3.19 respectively. The symptoms improved from the 8th week, and the difference was statistically significant compared with that before treatment (P < 0.05);The total amount of Demodex was 17 (11.5, 26.25), 13.5 (11, 18.75), 11.5 (8.5, 16.75), 7 (5.25, 11.25) and 6 (1.75, 7.75) respectively. From the 8th week, the total amount of Demodex was lower than that before treatment (P < 0.05). The number of Demodex decreased mainly in adults (P < 0.05), but there was no significant difference in the number of eggs and larvae (P ≥ 0.05). Conclusion: IPL is an effective method for the treatment of refractory Demodex blepharitis.
