Cancer cells secrete small extracellular vesicles(sEVs)to regulate various cellular functions,like tumor growth and metastasis,by promoting epithelial-mesenchymal transition and angiogenesis[1,2].Additionally,cancer c...Cancer cells secrete small extracellular vesicles(sEVs)to regulate various cellular functions,like tumor growth and metastasis,by promoting epithelial-mesenchymal transition and angiogenesis[1,2].Additionally,cancer cells evade immune surveillance by upregulating the surface expression of cellular programmed death-ligand 1(cPDL1),which interacts with programmed cell death-1(PD-1)on cytotoxic T cells,suppressing immune responses[3].展开更多
基金supported by the Bio&Medical Technology Development Program of the National Research Foundation(NRF)of Korea funded by the Korean government(MSIT)(2022R1A2C109214511 and 2020M3A9I4039539)the National Research Foundation of Korea(NRF)grant funded by the Korean government(MSIT)(2021R1A5A2021614,2023R1A2C3005553)the DGIST Program of the Ministry of Science and ICT(21-DGRIP-01).
文摘Cancer cells secrete small extracellular vesicles(sEVs)to regulate various cellular functions,like tumor growth and metastasis,by promoting epithelial-mesenchymal transition and angiogenesis[1,2].Additionally,cancer cells evade immune surveillance by upregulating the surface expression of cellular programmed death-ligand 1(cPDL1),which interacts with programmed cell death-1(PD-1)on cytotoxic T cells,suppressing immune responses[3].
