The SiTian project,with its vast field of view,will become an ideal platform for scientific research on asteroids.In this study,we develop a pipeline to analyze the photometry of asteroids and derive their periods fro...The SiTian project,with its vast field of view,will become an ideal platform for scientific research on asteroids.In this study,we develop a pipeline to analyze the photometry of asteroids and derive their periods from the data collected by the SiTian pathfinder project Mini-SiTian(MST).The pipeline is applied to the MST f02 region,an MST test region with a sky area of 2°.29×1°.53.Rotation periods of 22 asteroids are derived by the obtained light curve analysis.Among them,there are eight asteroids available in the Asteroid Lightcurve Photometry Database(ALCDEF),and six of them with more photometric points(>200)that have similar period parameters as the ones in ALCDEF.Additionally,the periods for 14 of these asteroids are newly obtained and are not listed in ALCDEF.This study demonstrates the feasibility of asteroid photometric research by the SiTian project.It shows that future observations from the SiTian project will provide even more photometry of asteroids,significantly increasing the number of available light curves.The potential vast photometric data on asteroids will help us to further understand the physics of asteroids,their material composition,and the formation and evolution of the solar system.展开更多
The emergence of nanozymes has significantly propelled the advancement of lateral flow immunoassays(LFIAs).Among these,atomically dispersed single-atom nanozymes are considered particularly advantageous for enhancing ...The emergence of nanozymes has significantly propelled the advancement of lateral flow immunoassays(LFIAs).Among these,atomically dispersed single-atom nanozymes are considered particularly advantageous for enhancing sensor performance due to their high density of active sites,superior catalytic activity,and favorable surface properties.In this study,we designed a colorimetric-catalytic signal amplification LFIA mediated by the Fe-Fe single atom nanozyme(Fe_(2)NC)for the detection of capsaicin(CAP),a critical indicator of gutter oil that persists even after rough and fine processing.The Fe_(2)NC exhibited high oxidase-like activity and was capable of directly catalyzing the conversion of O_(2) to reactive oxygen species(·O^(2-)and _(1)O_(2))without the need of H_(2)O_(2).The Vmax of Fe_(2)NC was 3.73×10^(-7)Ms^(-1) and the Km value was 0.199 mM according to the enzymatic reaction kinetics calculation.The colorless 3,3′,5,5′-tetramethylbenzidine(TMB)was oxidized to the blue ox-TMB by Fe_(2)NC,which was then superimposed on the strip for signal amplification.It was evident that the color intensity of the Tline of Fe_(2)NC-TMB-LFIA underwent noticeable attenuation when the CAP concentration was 0.05 ng/mL,and the color completely disappeared when the CAP concentration reached 1 ng/mL.Concurrently,the quantitative detection range of Fe_(2)NC-TMB-LFIA was calculated to be 0.01–1 ng/mL.Compared to AuNPs-LFIA,the Fe_(2)NCLFIA and Fe_(2)NC-TMB-LFIA demonstrated 2.5-fold and 10-fold improvements in sensitivity,respectively,and achieved a 2.5-fold and 5-fold reduction in antigen concentration.As a consequence,antigen cost was effectively decreased.This research offers a valuable reference for enhancing the sensitivity of immunoassay-based detection methods.展开更多
基金supports from the National Natural Science Foundation of China(NSFC,grant Nos.12203002 and 11973015)supports from the National Key Basic R&D Program of China via 2023YFA1608303 and the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0550103)+6 种基金supports from the National Natural Science Foundation of China(NSFCgrant No.12373015)supports from the National Natural Science Foundation of China(NSFCgrant Nos.12120101003 and 12373010)National Key R&D Program of China(grant Nos.2023YFA1607800,2023YFA1607804,2022YFA1602902)Beijing Municipal Natural Science Foundation(grant No.1222028)Strategic Priority Research Program of the Chinese Academy of Science(grant Nos.XDB0550100 and XDB0550000).
文摘The SiTian project,with its vast field of view,will become an ideal platform for scientific research on asteroids.In this study,we develop a pipeline to analyze the photometry of asteroids and derive their periods from the data collected by the SiTian pathfinder project Mini-SiTian(MST).The pipeline is applied to the MST f02 region,an MST test region with a sky area of 2°.29×1°.53.Rotation periods of 22 asteroids are derived by the obtained light curve analysis.Among them,there are eight asteroids available in the Asteroid Lightcurve Photometry Database(ALCDEF),and six of them with more photometric points(>200)that have similar period parameters as the ones in ALCDEF.Additionally,the periods for 14 of these asteroids are newly obtained and are not listed in ALCDEF.This study demonstrates the feasibility of asteroid photometric research by the SiTian project.It shows that future observations from the SiTian project will provide even more photometry of asteroids,significantly increasing the number of available light curves.The potential vast photometric data on asteroids will help us to further understand the physics of asteroids,their material composition,and the formation and evolution of the solar system.
基金supported by the National Key Research and Development Program of China(2023YFF1105101,2022YFF1102900)the Hunan Provincial Natural Science Foundation of China(2022JJ10046,2025JJ60155,2024JJ6021)Postgraduate Scientific Research Innovation Project of Hunan Province(QL20230225).
文摘The emergence of nanozymes has significantly propelled the advancement of lateral flow immunoassays(LFIAs).Among these,atomically dispersed single-atom nanozymes are considered particularly advantageous for enhancing sensor performance due to their high density of active sites,superior catalytic activity,and favorable surface properties.In this study,we designed a colorimetric-catalytic signal amplification LFIA mediated by the Fe-Fe single atom nanozyme(Fe_(2)NC)for the detection of capsaicin(CAP),a critical indicator of gutter oil that persists even after rough and fine processing.The Fe_(2)NC exhibited high oxidase-like activity and was capable of directly catalyzing the conversion of O_(2) to reactive oxygen species(·O^(2-)and _(1)O_(2))without the need of H_(2)O_(2).The Vmax of Fe_(2)NC was 3.73×10^(-7)Ms^(-1) and the Km value was 0.199 mM according to the enzymatic reaction kinetics calculation.The colorless 3,3′,5,5′-tetramethylbenzidine(TMB)was oxidized to the blue ox-TMB by Fe_(2)NC,which was then superimposed on the strip for signal amplification.It was evident that the color intensity of the Tline of Fe_(2)NC-TMB-LFIA underwent noticeable attenuation when the CAP concentration was 0.05 ng/mL,and the color completely disappeared when the CAP concentration reached 1 ng/mL.Concurrently,the quantitative detection range of Fe_(2)NC-TMB-LFIA was calculated to be 0.01–1 ng/mL.Compared to AuNPs-LFIA,the Fe_(2)NCLFIA and Fe_(2)NC-TMB-LFIA demonstrated 2.5-fold and 10-fold improvements in sensitivity,respectively,and achieved a 2.5-fold and 5-fold reduction in antigen concentration.As a consequence,antigen cost was effectively decreased.This research offers a valuable reference for enhancing the sensitivity of immunoassay-based detection methods.
