Sepsis causes gut mucosal metabolic derangem-ints and has been implicated in altered barrier func-tion.Insulin-like growth factor-I（IGF-I）has beenshown to accelerate somatic growth,as well as to in-duce growth of th...Sepsis causes gut mucosal metabolic derangem-ints and has been implicated in altered barrier func-tion.Insulin-like growth factor-I（IGF-I）has beenshown to accelerate somatic growth,as well as to in-duce growth of the gut.To investigate the effect ofIGF-I on gut mucosal metabolism and barrier functionin sepsis,32 male wistar rats underwent cecal ligationwere randomized to 2 groups:IGF-I（n=17）re-ceived parenteral nutrition（PN）plus IGF-I 4mg.kg.<sup>-1</sup>d<sup>-1</sup>and control group（n=15）received PNonly,or 3 days.On day 4,body weight（BW）gain,展开更多
文摘Sepsis causes gut mucosal metabolic derangem-ints and has been implicated in altered barrier func-tion.Insulin-like growth factor-I（IGF-I）has beenshown to accelerate somatic growth,as well as to in-duce growth of the gut.To investigate the effect ofIGF-I on gut mucosal metabolism and barrier functionin sepsis,32 male wistar rats underwent cecal ligationwere randomized to 2 groups:IGF-I（n=17）re-ceived parenteral nutrition（PN）plus IGF-I 4mg.kg.<sup>-1</sup>d<sup>-1</sup>and control group（n=15）received PNonly,or 3 days.On day 4,body weight（BW）gain,
