Direct stimulation of peripheral nerves with implantable electrodes successfully provided sensory feedback to amputees while using hand prostheses.Longevity of the electrodes is key to success,which we have improved f...Direct stimulation of peripheral nerves with implantable electrodes successfully provided sensory feedback to amputees while using hand prostheses.Longevity of the electrodes is key to success,which we have improved for the polyimide-based transverse intrafascicular multichannel electrode(TIME).The TIMEs were implanted in the median and ulnar nerves of three trans-radial amputees for up to six months.We present a comprehensive assessment of the electrical properties of the thin-film metallization as well as material status post explantationem.The TIMEs stayed within the electrochemical safe limits while enabling consistent and precise amplitude modulation.This lead to a reliable performance in terms of eliciting sensation.No signs of corrosion or morphological change to the thin-film metallization of the probes was observed by means of electrochemical and optical analysis.The presented longevity demonstrates that thin-film electrodes are applicable in permanent implant systems.展开更多
In this article,the affiliation details for Paolo Maria Rossini were Institute of Neurology,Catholic University of the Sacred Heart,Roma,Italy,and Polyclinic A.Gemelli Foundation-IRCCS,Roma,Italy but should have been ...In this article,the affiliation details for Paolo Maria Rossini were Institute of Neurology,Catholic University of the Sacred Heart,Roma,Italy,and Polyclinic A.Gemelli Foundation-IRCCS,Roma,Italy but should have been Department of Neuroscience&Neurorehabilitation,IRCCS San Raffaele Roma,00166 Rome,Italy.The original article has been corrected.展开更多
文摘Direct stimulation of peripheral nerves with implantable electrodes successfully provided sensory feedback to amputees while using hand prostheses.Longevity of the electrodes is key to success,which we have improved for the polyimide-based transverse intrafascicular multichannel electrode(TIME).The TIMEs were implanted in the median and ulnar nerves of three trans-radial amputees for up to six months.We present a comprehensive assessment of the electrical properties of the thin-film metallization as well as material status post explantationem.The TIMEs stayed within the electrochemical safe limits while enabling consistent and precise amplitude modulation.This lead to a reliable performance in terms of eliciting sensation.No signs of corrosion or morphological change to the thin-film metallization of the probes was observed by means of electrochemical and optical analysis.The presented longevity demonstrates that thin-film electrodes are applicable in permanent implant systems.
文摘In this article,the affiliation details for Paolo Maria Rossini were Institute of Neurology,Catholic University of the Sacred Heart,Roma,Italy,and Polyclinic A.Gemelli Foundation-IRCCS,Roma,Italy but should have been Department of Neuroscience&Neurorehabilitation,IRCCS San Raffaele Roma,00166 Rome,Italy.The original article has been corrected.
