Objective:Based on the theories of“defensive Qi entering Yin”and“Qi and blood in meridians”in traditional Chinese medicine(TCM),this study explores the synergistic intervention effect of the Brain Health Sleep-Aid...Objective:Based on the theories of“defensive Qi entering Yin”and“Qi and blood in meridians”in traditional Chinese medicine(TCM),this study explores the synergistic intervention effect of the Brain Health Sleep-Aid Pillow on brain diseases(such as insomnia,vertigo)and cervical spondylosis.The pillow achieves“marrow sea replenishment and unobstructed cerebral collaterals”by regulating cerebral blood perfusion and cervical mechanical balance through linear pulsed magnetic guidance of the Du Meridian and Bladder Meridian.Methods:A total of 120 patients with“neck impediment”and“insomnia”who met the Criteria for Diagnosis and Therapeutic Effect of TCM Syndromes were enrolled.They were randomly divided into an experimental group(60 cases,using Yuxuangong magnetic therapy pillow)and a control group(60 cases,using ordinary buckwheat pillow)by block randomization.The intervention lasted for 8 weeks.The efficacy was comprehensively evaluated using indicators including TCM syndrome scores,tongue and pulse analysis,cervical range of motion assessment,sleep quality(PSQI scale),and transcranial Doppler(TCD)[1].Results:The total TCM syndrome score in the experimental group decreased significantly more than that in the control group(-4.5±1.2 vs.-2.3±0.8,P<0.001);The cervical flexion range of motion increased by 15.3°±3.2°(P<0.01),and the total PSQI score decreased by 6.5 points(P<0.001);In the experimental group,the vertebral artery blood flow velocity increased by 12.3%(P<0.05),and the serum IL-6 level decreased by 0.08 pg/mL(P<0.05)[2].Conclusion:The Yuxuangong Brain Health Sleep-Aid Pillow provides a modern scientific interpretation of the TCM theory of“defensive Qi entering Yin”through a three-dimensional mechanism of“magnetic field regulating Qi and dredging collaterals,and physical mechanical reset”,which has significant clinical transformation value[3].展开更多
Hydrogenating CO_(2)is acknowledged as a structure-sensitive reaction, where structural changes of catalysts profoundly influence the product distribution and catalysts activity. However, traditional characterization ...Hydrogenating CO_(2)is acknowledged as a structure-sensitive reaction, where structural changes of catalysts profoundly influence the product distribution and catalysts activity. However, traditional characterization techniques(so-called ex situ) fail to accurate and authentic detection of the structure of catalysts and reaction pathway changes when the catalyst is in the working state. To address this issue, in situ/operando spectroscopies have been developed to elucidate the structure-activity relationships of catalysts in the thermo-catalytic CO_(2)hydrogenation process, advancing our understanding and guiding the design of catalysts. In particular, Raman spectroscopy and X-ray absorption spectroscopy(XAS) can be used to monitor the real-time changes of catalyst structures, elucidating the metal(or oxide)-support interaction, identifying active sites and investigating the causes of catalyst deactivation. Fourier-transform infrared spectroscopy(FTIR) can be employed to track the evolution of surface intermediates during the reaction, inferring plausible reaction mechanisms. Combined with steady-state isotope transient kinetic analysis(SSITKA) experiments, it provides valuable insights into the kinetics information of surface species. In this review, we summarize the up-to-date advances in these spectroscopic techniques and delineate potential future trends in the CO_(2)reduction.展开更多
Lignocellulosic biomass is a critical renewable carbon resource,but most of its utilization is inefficient,and elec-trocatalytic oxidation is a promising method of upgrading lignocellulose into value-added fuels and c...Lignocellulosic biomass is a critical renewable carbon resource,but most of its utilization is inefficient,and elec-trocatalytic oxidation is a promising method of upgrading lignocellulose into value-added fuels and chemicals under mild operating conditions.Recently,efforts to enable conversion with a high efficiency and low energy con-sumption have been reported,but understanding the reaction mechanisms and realizing scaled-up applications of the electrooxidation of lignocellulosic biomass are still in their early stages.A timely overview of recently reported general reaction mechanisms,particularly the strategies developed for use in improving the reaction efficiencies,is necessary to inspire research regarding the highly efficient utilization of lignocellulose.Herein,we summa-rize the strategies developed to improve electrocatalytic performance in oxidative lignocellulose conversion.The organized summary includes strategies ranging from designing efficient electrocatalysts and adding functional co-catalysts or electrolytes to employing advanced electrolyzers.A comprehensive overview of representative examples should provide universal principles to yield insight into the reaction processes and guide the design of efficient electrocatalytic systems.Finally,the challenges and opportunities in developing the electrocatalytic oxidative upgrading of lignocellulosic biomass in the near future are proposed.展开更多
The Yarlung Tsangpo River on the Tibetan Plateau provides a unique natural environment for studying fish evolution and ecology.However,the genomes and genetic diversity of plateau fish species have been rarely reporte...The Yarlung Tsangpo River on the Tibetan Plateau provides a unique natural environment for studying fish evolution and ecology.However,the genomes and genetic diversity of plateau fish species have been rarely reported.Schizopygopsis younghusbandi,a highly specialized Schizothoracine species and economically important fish inhabiting the Yarlung Tsangpo River,is threatened by overfishing and biological invasion.Herein,we generated a chromosome-level genome of S.younghusbandi and whole-genome resequencing data for 59 individuals from six locations of the river.The results showed that the divergence time between S.younghusbandi and other primitive Schizothoracine species was~4.2 Mya,coinciding with the major phase of the Neogene Tibetan uplift.The expanded gene families enriched in DNA integration and replication,ion binding and transport,energy storage,and metabolism likely contribute to the adaption of this species.The S.younghusbandi may have diverged from other highly specialized Schizothoracine species in the Zanda basin during the Pliocene epoch,which underwent major population reduction possibly due to the drastic climate change during the last glacial period.Population analysis indicated that the ancient population might have originated upstream before gradually adapting to evolve into the populations inhabiting the mid-stream and downstream regions of the Yarlung Tsangpo River.In conclusion,the chromosome-level genome and population diversity of S.younghusbandi provide valuable genetic resources for the evolution,ecology,and conservation studies of endemic fishes on the Tibetan Plateau.展开更多
文摘Objective:Based on the theories of“defensive Qi entering Yin”and“Qi and blood in meridians”in traditional Chinese medicine(TCM),this study explores the synergistic intervention effect of the Brain Health Sleep-Aid Pillow on brain diseases(such as insomnia,vertigo)and cervical spondylosis.The pillow achieves“marrow sea replenishment and unobstructed cerebral collaterals”by regulating cerebral blood perfusion and cervical mechanical balance through linear pulsed magnetic guidance of the Du Meridian and Bladder Meridian.Methods:A total of 120 patients with“neck impediment”and“insomnia”who met the Criteria for Diagnosis and Therapeutic Effect of TCM Syndromes were enrolled.They were randomly divided into an experimental group(60 cases,using Yuxuangong magnetic therapy pillow)and a control group(60 cases,using ordinary buckwheat pillow)by block randomization.The intervention lasted for 8 weeks.The efficacy was comprehensively evaluated using indicators including TCM syndrome scores,tongue and pulse analysis,cervical range of motion assessment,sleep quality(PSQI scale),and transcranial Doppler(TCD)[1].Results:The total TCM syndrome score in the experimental group decreased significantly more than that in the control group(-4.5±1.2 vs.-2.3±0.8,P<0.001);The cervical flexion range of motion increased by 15.3°±3.2°(P<0.01),and the total PSQI score decreased by 6.5 points(P<0.001);In the experimental group,the vertebral artery blood flow velocity increased by 12.3%(P<0.05),and the serum IL-6 level decreased by 0.08 pg/mL(P<0.05)[2].Conclusion:The Yuxuangong Brain Health Sleep-Aid Pillow provides a modern scientific interpretation of the TCM theory of“defensive Qi entering Yin”through a three-dimensional mechanism of“magnetic field regulating Qi and dredging collaterals,and physical mechanical reset”,which has significant clinical transformation value[3].
基金supported by the National Natural Science Foundation of China (22272016)the Fundamental Research Funds for the Central Universities (DUT21RC(3)113)。
文摘Hydrogenating CO_(2)is acknowledged as a structure-sensitive reaction, where structural changes of catalysts profoundly influence the product distribution and catalysts activity. However, traditional characterization techniques(so-called ex situ) fail to accurate and authentic detection of the structure of catalysts and reaction pathway changes when the catalyst is in the working state. To address this issue, in situ/operando spectroscopies have been developed to elucidate the structure-activity relationships of catalysts in the thermo-catalytic CO_(2)hydrogenation process, advancing our understanding and guiding the design of catalysts. In particular, Raman spectroscopy and X-ray absorption spectroscopy(XAS) can be used to monitor the real-time changes of catalyst structures, elucidating the metal(or oxide)-support interaction, identifying active sites and investigating the causes of catalyst deactivation. Fourier-transform infrared spectroscopy(FTIR) can be employed to track the evolution of surface intermediates during the reaction, inferring plausible reaction mechanisms. Combined with steady-state isotope transient kinetic analysis(SSITKA) experiments, it provides valuable insights into the kinetics information of surface species. In this review, we summarize the up-to-date advances in these spectroscopic techniques and delineate potential future trends in the CO_(2)reduction.
基金supported by the National Natural Science Foundation of China(grant numbers 22275138,22271219,22071172,22375142).
文摘Lignocellulosic biomass is a critical renewable carbon resource,but most of its utilization is inefficient,and elec-trocatalytic oxidation is a promising method of upgrading lignocellulose into value-added fuels and chemicals under mild operating conditions.Recently,efforts to enable conversion with a high efficiency and low energy con-sumption have been reported,but understanding the reaction mechanisms and realizing scaled-up applications of the electrooxidation of lignocellulosic biomass are still in their early stages.A timely overview of recently reported general reaction mechanisms,particularly the strategies developed for use in improving the reaction efficiencies,is necessary to inspire research regarding the highly efficient utilization of lignocellulose.Herein,we summa-rize the strategies developed to improve electrocatalytic performance in oxidative lignocellulose conversion.The organized summary includes strategies ranging from designing efficient electrocatalysts and adding functional co-catalysts or electrolytes to employing advanced electrolyzers.A comprehensive overview of representative examples should provide universal principles to yield insight into the reaction processes and guide the design of efficient electrocatalytic systems.Finally,the challenges and opportunities in developing the electrocatalytic oxidative upgrading of lignocellulosic biomass in the near future are proposed.
基金supported by the National Natural Science Foundation of China[grant numbers 32160864,32072980]the National Natural Science Foundation of China(NSFC)Joint Fund Priority Support Program[grant number U23A20249]+1 种基金the National Talent Research Grant for 2023[grant number 5330500953]the Special Fund for Youth Team of the Southwest University[grant number SWUXJPY202302].
文摘The Yarlung Tsangpo River on the Tibetan Plateau provides a unique natural environment for studying fish evolution and ecology.However,the genomes and genetic diversity of plateau fish species have been rarely reported.Schizopygopsis younghusbandi,a highly specialized Schizothoracine species and economically important fish inhabiting the Yarlung Tsangpo River,is threatened by overfishing and biological invasion.Herein,we generated a chromosome-level genome of S.younghusbandi and whole-genome resequencing data for 59 individuals from six locations of the river.The results showed that the divergence time between S.younghusbandi and other primitive Schizothoracine species was~4.2 Mya,coinciding with the major phase of the Neogene Tibetan uplift.The expanded gene families enriched in DNA integration and replication,ion binding and transport,energy storage,and metabolism likely contribute to the adaption of this species.The S.younghusbandi may have diverged from other highly specialized Schizothoracine species in the Zanda basin during the Pliocene epoch,which underwent major population reduction possibly due to the drastic climate change during the last glacial period.Population analysis indicated that the ancient population might have originated upstream before gradually adapting to evolve into the populations inhabiting the mid-stream and downstream regions of the Yarlung Tsangpo River.In conclusion,the chromosome-level genome and population diversity of S.younghusbandi provide valuable genetic resources for the evolution,ecology,and conservation studies of endemic fishes on the Tibetan Plateau.
