Fibroblast growth factor 23(FGF23)is an osteocyte-and osteoblast-derived hormone that primarily regulates phosphate and vitamin D metabolism.Circulatory FGF23 levels are abnormally increased in pathological conditions...Fibroblast growth factor 23(FGF23)is an osteocyte-and osteoblast-derived hormone that primarily regulates phosphate and vitamin D metabolism.Circulatory FGF23 levels are abnormally increased in pathological conditions like acute or chronic kidney injury,resulting in disease progression as well as increased rates of morbidity and mortality.^(1) However,FGF23 production in acute liver injury is not fully investigated.In this study.展开更多
基金supported by the National Research Foundation(NRF)basic science research program Korean government(Ministry of Science and ICT),Republic of Korea(No.2020R1A6A3A01096145,2020)(No.NRF-2019R1C1C1005319,2019)(No.NRF-2017R1A6A3A04006167,2017)(No.NRF-2020R1A2C3006952,2020)and(No.NRF-2021R1A2C3004923,2021)The Federal Ministry of Education and Research-Liver Systems Medicine Program of the Stiftung für Biomedizinische Alkoholforschung,Germany(No.PTJ-031L0043).
文摘Fibroblast growth factor 23(FGF23)is an osteocyte-and osteoblast-derived hormone that primarily regulates phosphate and vitamin D metabolism.Circulatory FGF23 levels are abnormally increased in pathological conditions like acute or chronic kidney injury,resulting in disease progression as well as increased rates of morbidity and mortality.^(1) However,FGF23 production in acute liver injury is not fully investigated.In this study.
