Oral squamous cell carcinoma(OSCC),a major subgroup of head and neck squamous cell carcinoma(HNSCC),is an aggressive disease that preferentially spreads to cervical lymph nodes.Positive lymph node status is an importa...Oral squamous cell carcinoma(OSCC),a major subgroup of head and neck squamous cell carcinoma(HNSCC),is an aggressive disease that preferentially spreads to cervical lymph nodes.Positive lymph node status is an important predictor of survival in OSCC[1-3].Hence,a better understanding of the molecular mechanisms underlying oral cancer metastasis and the identification of therapeutic vulnerabilities are needed to prevent and treat metastatic disease.展开更多
基金supported by intramural funding from the Medical Faculty(Wilhelm-Roux program,FKZ32/19).
文摘Oral squamous cell carcinoma(OSCC),a major subgroup of head and neck squamous cell carcinoma(HNSCC),is an aggressive disease that preferentially spreads to cervical lymph nodes.Positive lymph node status is an important predictor of survival in OSCC[1-3].Hence,a better understanding of the molecular mechanisms underlying oral cancer metastasis and the identification of therapeutic vulnerabilities are needed to prevent and treat metastatic disease.
