N6-methyladenosine(m^(6)A)modification,the most abundant internal modification in messenger RNA(mRNA)and long non-coding RNA(lncRNA),has emerged as a critical epitranscriptomic regulatory mechanism in eukaryotes.While...N6-methyladenosine(m^(6)A)modification,the most abundant internal modification in messenger RNA(mRNA)and long non-coding RNA(lncRNA),has emerged as a critical epitranscriptomic regulatory mechanism in eukaryotes.While the importance of m^(6)A modification in various biological processes has been recognized,a comprehensive understanding of its diverse roles in plant biology and agricultural applications remains fragmented.This review analyzes recent advances inm^(6)A modification's biological functions in plants.m^(6)A modification plays crucial roles in multiple aspects of plant life,including seed germination,organ development,and reproductive structure formation.Furthermore,m^(6)A has been found to significantly influence plant responses to environmental stresses,including salt,drought,temperature,and heavy metal exposure.We also uncover m^(6)A involvement in important agricultural traits.This review provides insights into the mechanistic understanding of m^(6)A modification in plants and highlights its applications in agricultural improvement,offering a foundation for future research in crop enhancement and stress resistance.展开更多
目的对比分析国内外儿童保健领域的研究现状及热点,为促进我国儿童保健高质量发展提供参考依据。方法通过中国知网(CNKI)和Web of Science(WoS)核心数据库检索发表时间为2015年1月1日-2024年12月31日的儿童保健相关文献,运用VOSviewer...目的对比分析国内外儿童保健领域的研究现状及热点,为促进我国儿童保健高质量发展提供参考依据。方法通过中国知网(CNKI)和Web of Science(WoS)核心数据库检索发表时间为2015年1月1日-2024年12月31日的儿童保健相关文献,运用VOSviewer软件构建知识图谱,从发文趋势、研究机构分布及关键词共现等维度进行可视化分析。结果29535篇文献中,英文文献26014篇,中文文献3521篇。中文文献量呈下降趋势(年均降幅12.86%),英文文献量持续增长(年均增幅18.99%);国内研究主体为妇幼保健机构和医院(国内发文量前10位的机构中占比70%),国外则以高校为主导(国际发文量前10位的机构中占比90%);CNKI文献研究热点为“儿童保健”“生长发育”“影响因素”及“儿童保健服务”等;Web of Science文献研究热点为“照护”“患病率”“青少年”等。结论国内外儿童保健研究存在差异,但均呈现“预防-治疗”互补特征,建议加强跨学科融合,重点关注心理健康,提升临床研究能力,推动儿童保健高质量发展。展开更多
基金supported by the National Nature Science Foundation of China(Grant No.31660568)Guangxi Science and Technology major project(Grant No.GuikeAA22068088)+2 种基金start-up funding for introduced talents in Guangxi University,the Guangxi Colleges and Universities Young and Middle-aged Teachers'Basic Scientific Research Ability Improvement Project(Grant No.2024KY0010)Guangxi Graduate Education Innovation Program(Grant No.YCSW2024093)the Guangxi University Student Innovation and Entrepreneurship Training Program Funding Project(Grant Nos.202310593704,202310593714,202410953044S).
文摘N6-methyladenosine(m^(6)A)modification,the most abundant internal modification in messenger RNA(mRNA)and long non-coding RNA(lncRNA),has emerged as a critical epitranscriptomic regulatory mechanism in eukaryotes.While the importance of m^(6)A modification in various biological processes has been recognized,a comprehensive understanding of its diverse roles in plant biology and agricultural applications remains fragmented.This review analyzes recent advances inm^(6)A modification's biological functions in plants.m^(6)A modification plays crucial roles in multiple aspects of plant life,including seed germination,organ development,and reproductive structure formation.Furthermore,m^(6)A has been found to significantly influence plant responses to environmental stresses,including salt,drought,temperature,and heavy metal exposure.We also uncover m^(6)A involvement in important agricultural traits.This review provides insights into the mechanistic understanding of m^(6)A modification in plants and highlights its applications in agricultural improvement,offering a foundation for future research in crop enhancement and stress resistance.
文摘目的对比分析国内外儿童保健领域的研究现状及热点,为促进我国儿童保健高质量发展提供参考依据。方法通过中国知网(CNKI)和Web of Science(WoS)核心数据库检索发表时间为2015年1月1日-2024年12月31日的儿童保健相关文献,运用VOSviewer软件构建知识图谱,从发文趋势、研究机构分布及关键词共现等维度进行可视化分析。结果29535篇文献中,英文文献26014篇,中文文献3521篇。中文文献量呈下降趋势(年均降幅12.86%),英文文献量持续增长(年均增幅18.99%);国内研究主体为妇幼保健机构和医院(国内发文量前10位的机构中占比70%),国外则以高校为主导(国际发文量前10位的机构中占比90%);CNKI文献研究热点为“儿童保健”“生长发育”“影响因素”及“儿童保健服务”等;Web of Science文献研究热点为“照护”“患病率”“青少年”等。结论国内外儿童保健研究存在差异,但均呈现“预防-治疗”互补特征,建议加强跨学科融合,重点关注心理健康,提升临床研究能力,推动儿童保健高质量发展。
