Fueled by the increasing imperative for sustainable energy solutions and the burgeoning emphasis on health awareness,self-powered techniques have undergone notable strides in advancement.Triboelectric nanogenerators(T...Fueled by the increasing imperative for sustainable energy solutions and the burgeoning emphasis on health awareness,self-powered techniques have undergone notable strides in advancement.Triboelectric nanogenerators(TENGs)stand out as a prominent device capitalizing on the principles of triboelectrification and electrostatic induction to generate electricity or electrical signals.In efforts to augment the electrical output performance of TENGs and broaden their range of applications,researchers have endeavored to refine materials,surface morphology,and structural design.Among them,physical morphological modifications play a pivotal role in enhancing the electrical properties of TENGs by increasing the contact surface area,which can be achieved by building micro-/nano-structures on the surface or inside the friction material.In this review,we summarize the common morphologies of TENGs,categorize the morphologies into surface and internal structures,and elucidate their roles in enhancing the electric output performance of devices.Moreover,we systematically classify the methodologies employed for morphological preparation into physical and chemical approaches,thereby furnishing a comprehensive survey of the diverse techniques.Subsequently,typical applications of TENGs with special morphology divided by energy harvesting and self-powered sensors are presented.Finally,an overview of the challenges and future trajectories pertinent to TENGs is conducted.Through this endeavor,the aim of this article is to catalyze the evolution of further strategies for enhancing performance of TENGs.展开更多
The electrochemical CO_(2) reduction reaction(eCO_(2)RR),producing gaseous C_(2+)products such as ethylene(C_(2)H_(4)),represents a sustainable strategy to mitigate the greenhouse effect.Inspired by the promotion effe...The electrochemical CO_(2) reduction reaction(eCO_(2)RR),producing gaseous C_(2+)products such as ethylene(C_(2)H_(4)),represents a sustainable strategy to mitigate the greenhouse effect.Inspired by the promotion effect of the cyano group(-C≡N) for C-C coupling in organic chemistry,several cyano-containing organocatalysts have been found to be capable of directly converting CO_(2) into C_(2)H_(4) with-C≡N as the active center during the eCO_(2)RR.The selectivity of C_(2)H_(4) for the representative catalyst,metal-free dicyandiamide(DCD),reached 27.6 % after partial hydrogenation in KHCO_(3) solution.In addition,its selectivity can be further improved to 57.7 % when coupled with oriented Cu crystals.The experimental and computational results collectively reveal that charge redistribution between Cu{100} and DCD promotes the partial hydrogenation of the cyano group and lays the foundation for the reduced energy barrier for the CO_(2) reduction on-C≡N.This study breaks the limitations of traditional metal/metal oxide-based catalysts by using cyano-containing organocatalysts for direct C_(2+) product generation,expanding the eCO_(2)RR catalyst library.In addition,this research elucidates the role of charge redistribution and cyano group hydrogenation in lowering reaction barriers,providing fundamental guidance for the design of new organocatalysts.展开更多
Stimulus-responsive actuators are novel functional devices capable of sensing external stimuli and ex-hibiting specific deformation responses.MXene,owing to its unique 2D structure and efficient energy conversion effi...Stimulus-responsive actuators are novel functional devices capable of sensing external stimuli and ex-hibiting specific deformation responses.MXene,owing to its unique 2D structure and efficient energy conversion efficiency,has bridged the gap in traditional devices and shown great potential for multiple stimulus-responsive actuators.However,the drawbacks of pure MXene films,including susceptibility to oxidation and vulnerability to shear stress,hinder their applications.Through composite modification and structural design strategies,a three-layer structured MXene-carbon nanotubes hybrid film(tHCM)is fabri-cated,exhibiting a tensile strength and fracture strain of 153.8 MPa and 4.65%,respectively,representing improvements of 598.4%and 226.8%compared to the initial film.Meanwhile,the film maintains excel-lent stability demonstrating the enhancing effects of hydrogen bonds and densely packed structure.The hybrid films demonstrate unique and facile welding features due to splicing properties,enabling the for-mation of complex configurations.In terms of electro-/photo-thermal conversion performance,the hybrid film can reach a reasonably high temperature of 250℃at low voltage(2.5 V)and 110.6℃under 150 mW cm^(-2) infrared light.Leveraging the thermal expansion mismatch between tHCM and thermoplastic films,an integrated,flexible,and weldable actuator with unique electro/photo-response is developed,and vari-ous biomimetic driving applications,particularly,the light-mediated hierarchical transmission and precise motion along predetermined trajectory are realized.This work not only provides an effective strategy for modifying MXene composite films but also advances the design of novel actuators,offering broad appli-cation prospects in fields such as stimulus-responsive actuated robots and cargo transportation.展开更多
Realizing the point-of-care tumor markers biodetection with good convenience and high sensitivity possesses great significance for prompting cancer monitoring and screening in biomedical study field.Herein,the quantum...Realizing the point-of-care tumor markers biodetection with good convenience and high sensitivity possesses great significance for prompting cancer monitoring and screening in biomedical study field.Herein,the quantum dots luminescence and microfluidic biochip with machine vision algorithm-based intelligent biosensing platform have been designed and manufactured for point-of-care tumor markers diagnostics.The employed quantum dots with excellent photoluminescent performance are modified with specific antibody as the optical labeling agents for the designed sandwich structure immunoassay.The corresponding biosensing investigations of the designed biodetection platform illustrate several advantages involving high sensitivity(~0.021 ng mL^(−1)),outstanding accessibility,and great integrability.Moreover,related test results of human-sourced artificial saliva samples demonstrate better detection capabilities compared with commercially utilized rapid test strips.Combining these infusive abilities,our elaborate biosensing platform is expected to exhibit potential applications for the future point-of-care tumor markers diagnostic area.展开更多
Sr2SiO4: Eu phosphor for white light emitting diodes (LEDs) was synthesized by employing an as-prepared (Sr, Eu)CO3@SiO2 core-shell precursor as starting materials, and the effect of the core-shell precursor was also ...Sr2SiO4: Eu phosphor for white light emitting diodes (LEDs) was synthesized by employing an as-prepared (Sr, Eu)CO3@SiO2 core-shell precursor as starting materials, and the effect of the core-shell precursor was also discussed on the crystal structure, particle morphology and luminescent properties of the resultant phosphor. The results showed that the hybrid β- and α′-Sr2SiO4: Eu phosphor with fine particle size and narrow distribution could be obtained at a lower firing temperature than that in conventional solidstate reaction method, and its formation mechanism was deduced to be (Sr, Eu)CO3 diffusion controlled reaction process. Responded to its hybrid crystal structure, this phosphor exhibited the combined luminescence of β- and α′-Sr2SiO4: Eu.展开更多
Adenoid basal carcinoma(ABC)of the cervix is a rare and low-incidence low-grade cervical cancer.In our practice,we encountered a case of cervical ABC with squamous differentiation and high-grade squamous intraepitheli...Adenoid basal carcinoma(ABC)of the cervix is a rare and low-incidence low-grade cervical cancer.In our practice,we encountered a case of cervical ABC with squamous differentiation and high-grade squamous intraepithelial lesion(HSIL)with gland involvement in the peripheral cervix.Reviewing relevant literature and analyzing its clinical manifestations,pathological morphology,and immunohistochemical characteristics would help deepen the understanding of this malignant tumor,so as to make a comprehensive diagnosis with differential diagnosis and prevent misdiagnosis.展开更多
The persistent pursuit of miniaturization and energy efficiency in semiconductor technology has driven the scaling of complementary metal-oxide-semiconductor field-effect transistors(CMOS FETs,i.e.,the MOSFETs)to thei...The persistent pursuit of miniaturization and energy efficiency in semiconductor technology has driven the scaling of complementary metal-oxide-semiconductor field-effect transistors(CMOS FETs,i.e.,the MOSFETs)to their physical limits.Conventional MOSFETs face intrinsic challenges,especially the Boltzmann limit that imposes a fundamental lower bound on the subthreshold swing(SS≥60 mV dec^(−1)at room temperature).This limitation severely restricts voltage scaling and exacerbates static power dissipation.To overcome these bottlenecks,tunnel field-effect transistors(TFETs)have emerged as a promising post-CMOS alternative.The advantages of ultra-small SS well below the Boltzmann limit,as well as ultralow leakage currents,make TFETs ideal for low-power electronics and energy-efficient computing in the future information industry.However,its current development has encountered significant resistance to further performance improvement requirements;new breakthroughs have evolved to be based on interdisciplinary research that covers materials science,device technology,theoretical physics,and so on.Here,we provide a review on the design and development of TFET,which mainly describes the device physics model of tunnel junctions,and discusses the optimization direction of key parameters,the design direction of potential structures,and the development direction of the innovation system based on the device physics.Also,we visualize the framework for the figures of merit of TFET performance and further forecast the future applications of TFET.展开更多
Persistent luminescence nanomaterials can remain luminescence when the light source is turned off,which exhibits promise in biosensor and bioimaging fields since they have the ability to completely eradicate tissue au...Persistent luminescence nanomaterials can remain luminescence when the light source is turned off,which exhibits promise in biosensor and bioimaging fields since they have the ability to completely eradicate tissue autofluorescence.Although significant progress has been made in the persistent luminescence biosensing,there is still a dearth of long-afterglow detection platform with low limit of detection(LOD)and high sensitivity.Herein,Zn_(2)GeO_(4):Mn,Cr persistently luminescent nanorods(PLNRs)with superior persistent luminescence and long afterglow time were developed.The addition of Cr^(3+)manifestly improves persistent luminescence intensity and afterglow duration through creating a deep defect trap.Then the biosensors were constructed by combining the Zn_(2)GeO_(4):Mn,Cr PLNRs-antibody and Fe_(3)O_(4) magnetic nanoparticles(MNPs)-antibody for nucleocapsid protein detection based on electrostatic attraction.The LOD value for nucleocapsid protein realizes as low as 39.82 ag/mL,which is much lower than the previously reported persistent luminescent-based biosensors.Accordingly,the low detection sensitivity is attributed to fluorescence resonance energy transfer.In addition,high specificity is also achieved.Therefore,the as-prepared Zn_(2)GeO_(4):Mn,Cr persistently luminescent materials can act as the promising candidate in biosensors applications.This strategy provides effective guidance for the development of biosensing platforms with high sensitivity and specificity.展开更多
The aggregation ofα-synuclein(ɑ-syn)coupled with overexpressed neuroinflammation instigates the degeneration of dopaminergic neurons,thereby aggravating the progression of Parkinson’s disease(PD).Herein,we introduc...The aggregation ofα-synuclein(ɑ-syn)coupled with overexpressed neuroinflammation instigates the degeneration of dopaminergic neurons,thereby aggravating the progression of Parkinson’s disease(PD).Herein,we introduced a series of hydrophobic amino acid-based carbon dots(CDs)for inhibitingɑ-syn aggregation and mitigating the inflammation in PD neurons.Significantly,we show that phenylalanine CDs(Phe-CDs)could strongly bind withɑ-syn monomers and dimers via hydrophobic force,maintain their stability,and inhibit their further aggregation in situ and in vitro,finally conferring neuroprotection in PD by rescuing synaptic loss,ameliorating mitochondrial dysfunctions,and modulating Ca^(2+)flux.Importantly,Phe-CDs demonstrate the ability to penetrate the blood-brain barrier,significantly improving motor performance in PD mice.Our findings suggest that Phe-CDs hold great promise as a therapeutic agent for PD and the related neurodegenerative disease.展开更多
Designing new materials with high-performance resistive switching(RS)behaviors and/or developing alternative means to modulate the RS behaviors are of great significance for information storage and neuromorphic comput...Designing new materials with high-performance resistive switching(RS)behaviors and/or developing alternative means to modulate the RS behaviors are of great significance for information storage and neuromorphic computing.Herein,we present a novel strategy to design and synthesize furan-annulated naphthalenes for high-performance digital and analog RS behaviors through controlling substituents.By introducing an electron acceptor of trifluoromethyl on the phenyl ring,3-phenyl-4-(4-trifluoromethylphenyl)-2H-naphtho[1,8-bc]furan(TPNF)is synthesized with donor–acceptor(D–A)pairs by utilizing the electron donor of furyl in the naphthalene.Owing to the constructed D–A systems where electrons can be transported under the external bias voltage,the prepared TPNF thin films demonstrate high-performance bipolar digital RS behaviors with multilevel storage characteristics.On the other hand,if the substituent on the phenyl ring is replaced by an electron donor of methoxy,4-(4-methoxyphenyl)-3-phenyl-2H-naphtho[1,8-bc]furan(MPNF)can be constructed with only electron-donor units of furyl and methoxy.The fabricated MPNF thin films show analog RS behaviors owing to the carrier trapping/detrapping from the nucleophilic trapping sites generated from the electron-donor units.The analog memristors demonstrate synaptic functions with high linearity of conductance modulation,which is highly desirable for neuromorphic computing.Such synaptic memristors based on MPNF are completely capable of recognizing digit images with high accuracy(95.2%)and implementing decimal arithmetic of addition,subtraction,multiplication,and division operations.This study provides a feasible way to modulate the RS properties by the strategy of introducing different substituents,demonstrating promising applications of such well-designed organic semiconductors for multilevel storage and neuromorphic computing.展开更多
The aggregation ofα-synuclein(ɑ-syn)coupled with overexpressed neuroinflammation instigates the degeneration of dopaminer-gic neurons,thereby aggravating the progression of Parkinson’s disease(PD).Herein,we introdu...The aggregation ofα-synuclein(ɑ-syn)coupled with overexpressed neuroinflammation instigates the degeneration of dopaminer-gic neurons,thereby aggravating the progression of Parkinson’s disease(PD).Herein,we introduced a series of hydrophobic amino acid–based carbon dots(CDs)for inhibitingɑ-syn aggregation and mitigating the inflammation in PD neurons.Significantly,we show phenylalanine CDs(Phe-CDs)could strongly bind withɑ-syn monomers and dimers via hydrophobic force,maintain their stability,and inhibit their further aggregates in situ and in vitro,finally conferring neuroprotection in PD by rescuing synaptic loss,ameliorating mitochondrial dysfunctions,and modulating Ca^(2+) flux.Importantly,Phe-CDs demonstrate the ability to penetrate the blood–brain barrier(BBB),significantly improving motor performance in PD mice.Our findings suggest that Phe-CDs hold great promise as a therapeutic agent for PD and the relative neurodegenerative disease.展开更多
MXene exhibits notable piezoelectric properties,making it a promising material for high-performance piezoelectric nanogenerators(PENGs)in next-generation smart wearable devices and bioelectronics.However,current MXene...MXene exhibits notable piezoelectric properties,making it a promising material for high-performance piezoelectric nanogenerators(PENGs)in next-generation smart wearable devices and bioelectronics.However,current MXene-based PENGs face challenges such as insufficient mechanical robustness,low piezoelectric response,and limited long-term functionality.These limitations primarily stem from the small effective area and low strain levels of MXene nanosheets.Here,we constructed a high-entropy TiVCrMoC3Tx MXene composite film by leveraging strong hydrogen bonding interactions between MXene and polyvinyl alcohol(PVA),which was further developed into a self-powered flexible nanogenerator.The resulting device exhibited a significant piezoresponse with output signals of 500 mV and 790 pA under a compressive force of 3.47 N,along with considerable long-term functionality over 1500 cycles.Moreover,a hydrofluoric-free etching approach was employed to synthesize the high-entropy MXene nanosheets,which ensures the safety and biocompatibility for bioelectronics applications.This work highlights the potential of high-entropy MXene for sustainable applications in wearable electronics and energy harvesting.展开更多
Ever since discovery of graphene,two-dimensional(2D)materials become a new tool box for information technology.Among the 2D family,ultrathin bismuth(Bi)has attracted a great deal of attention in recent years due to it...Ever since discovery of graphene,two-dimensional(2D)materials become a new tool box for information technology.Among the 2D family,ultrathin bismuth(Bi)has attracted a great deal of attention in recent years due to its unique topological insulating properties and large magnetoresistance.However,the scalable synthesis of layered Bi ultrathin films is rarely been reported,which would greatly restrict further fundamental investigation and practical device development.Here,we demonstrate the direct growth of homogeneous and centimeter-scale layered Bi films by pulsed laser deposition(PLD)technique.The as-grown Bi film exhibits high-purity phase and good crystallinity.In addition,both(111)and(110)-oriented Bi films can be synthesized by precisely controlling the processing temperature.The characterization of optical properties shows a thickness dependent band gaps(0.075-0.2 eV).Moreover,Bi thin-film-based field-effect transistors have been demonstrated,exhibiting a large carrier mobility of 220 cm2 V−1 s−1.Our work suggests that the PLD-grown Bi films would hold the potential to develop spintronic applications,electronic and optoelectronic devices used for information science and technology.展开更多
Two-dimensional(2D)ferroelectric materials with unique structure and extraordinary optoelectrical properties have attracted intensive research in the field of nanoelectronic and optoelectronic devices,such as optical ...Two-dimensional(2D)ferroelectric materials with unique structure and extraordinary optoelectrical properties have attracted intensive research in the field of nanoelectronic and optoelectronic devices,such as optical sensors,transistors,photovoltaics and non-volatile memory devices.However,the transition temperature of the reported ferroelectrics in 2D limit is generally low or slightly above room temperature,hampering their applications in high-temperature electronic devices.Here,we report the robust high-temperature ferroelectricity in 2D a-In2Se3,grown by chemical vapor depostion(CVD),exhibiting an out-of-plane spontaneous polarization reaching above 200℃.The polarization switching and ferroelectric domains are observed in In2Se;nanoflakes in a wide temperature range.The coercive field of the CVD grown ferroelectric layers ilustrates a room-temperature thickness dependency and increases drastically when the film thickness decreases;whereas there is no large variance in the coercive field at dfterent termperature from the samples with identical thickness.The results show the stable ferroelectricit of In2Se3 nanoflakes maintained at high temperature and open up the opportunities of 2D materials for novel applications in high-temperature nanoelectronic devices.展开更多
Lanthanide ions have attracted great attention due to their distinct photonic properties.The optoelectronic properties and device performance are greatly affected by the interfacial coupling between the layered van de...Lanthanide ions have attracted great attention due to their distinct photonic properties.The optoelectronic properties and device performance are greatly affected by the interfacial coupling between the layered van der Waals heterostructure,fabricated with two or more transition metal dichalcogenide(TMD)layers.In this work,lanthanide-doped WS2/MoS2 layered heterostructures have been constructed through two synthesis steps.The doped thin films are highly textured nanosheets on wafers.Importantly,the as-prepared heterostructure exhibits efficient near-infrared emission in the range of the telecommunication window,owing to energy transfer between lanthanide ions in the two TMD layers.The use of the layered heterostructure allows the decrease of deleterious cross-relaxation due to homogeneous doping or concentration quenching.The energy transfer process was further elaborated in this work.The results suggest that lanthanide ions can effectively extend the emission band of TMD thin films and their heterostructures.The doped TMD heterostructure is highly favourable for constructing atomically thin near-infrared photonic devices.展开更多
Lanthanide-doped upconversion nanocrystals(UCNCs)have recently become an attractive nonlinear fluorescence material for use in bioimaging because of their tunable spectral characteristics and exceptional photostabilit...Lanthanide-doped upconversion nanocrystals(UCNCs)have recently become an attractive nonlinear fluorescence material for use in bioimaging because of their tunable spectral characteristics and exceptional photostability.Plasmonic materials are often introduced into the vicinity of UCNCs to increase their emission intensity by means of enlarging the absorption cross-section and accelerating the radiative decay rate.Moreover,plasmonic nanostructures(e.g.,gold nanorods,GNRs)can also influence the polarization state of the UC fluorescence—an effect that is of fundamental importance for fluorescence polarization-based imaging methods yet has not been discussed previously.To study this effect,we synthesized GNR@SiO_(2)@CaF2:Yb^(3+),Er^(3+)hybrid core–shell–satellite nanostructures with precise control over the thickness of the SiO_(2) shell.We evaluated the shell thicknessdependent plasmonic enhancement of the emission intensity in ensemble and studied the plasmonic modulation of the emission polarization at the single-particle level.The hybrid plasmonic UC nanostructures with an optimal shell thickness exhibit an improved bioimaging performance compared with bare UCNCs,and we observed a polarized nature of the light at both UC emission bands,which stems from the relationship between the excitation polarization and GNR orientation.We used electrodynamic simulations combined with Förster resonance energy transfer theory to fully explain the observed effect.Our results provide extensive insights into how the coherent interaction between the emission dipoles of UCNCs and the plasmonic dipoles of the GNR determines the emission polarization state in various situations and thus open the way to the accurate control of the UC emission anisotropy for a wide range of bioimaging and biosensing applications.展开更多
Modulation of light underpins a central part of modern optoelectronics.Con-ventional optical modulators based on refractive-index and absorption varia-tion in the presence of an electric field serve as the workhorse f...Modulation of light underpins a central part of modern optoelectronics.Con-ventional optical modulators based on refractive-index and absorption varia-tion in the presence of an electric field serve as the workhorse for diverse photonic technologies.However,these approaches based on electro-refraction or electro-absorption effect impose limitations on frequency converting and signal amplification.Lanthanide-activated phosphors offer a promising plat-form for nonlinear frequency conversion with an abundant spectrum.Here,we propose a novel approach to achieve frequency conversion and digital modula-tion of light signal by coupling lanthanide luminescence with an electrically responsive ferroelectric host.The technological benefits of such paradigm-shifting solution are highlighted by demonstrating a quasi-continuous and enhancement of the lanthanide luminescence.The ability to locally manipulate light emission can convert digital information signals into visible waveforms,and visualize electrical logic and arithmetic operations.The proof-of-concept device exhibits perspectives for developing light-compatible logic functions.These results pave the way to design more controllable lanthanide photonics with desired opto-electronic coupling.展开更多
In this article,the biodegradation process and bone formation of a mineralized collagen reconstruction rod embedding in necrosis of human femoral head were investigated by imageological and histological methods.Comput...In this article,the biodegradation process and bone formation of a mineralized collagen reconstruction rod embedding in necrosis of human femoral head were investigated by imageological and histological methods.Computed radiography(CR)computerized tomography(CT),common pathological section and hard tissue section analysis were used to evaluated the dynamics of imageological and histopathological changes of femoral head,interface between the host bone and implant and the bone reconstruction process.The results showed that the density of rods increased closed to that of host bones after 1 year implanting,and the interface between them turns to blurring.Hard tissue grinding sections analysis showed osteocytes appearing in sparse bone trabecular and bone pit region,as well as a few vessels in the degraded dye powder matrix were noticed,indicating the new bone forming between the implants and host bones.Regular decalcified sections analysis showed scattered osteoclasts,multinucleated giant cells and fibrosis components existing in the degraded rod and the host bone trabecular.Degraded debris was endocytosed by giant cells,and vascular network formed around the boundaries of the implanted rod.The good osteointegration has been expressed by the interface between the implanted rod and the host bone becoming blurred.Histological results indicated that the implanted rod degradation process and new bones regeneration simultaneously occurred around the boundaries of embedding rod.New bone and host bone were hinged and co-existed.展开更多
Outbreaks of infectious viruses offer a formidable challenge to public healthcare systems and early detection of viruses is essential for preventing virus propagation.In this work,an ultrasensitive plasmon-enhanced fl...Outbreaks of infectious viruses offer a formidable challenge to public healthcare systems and early detection of viruses is essential for preventing virus propagation.In this work,an ultrasensitive plasmon-enhanced fluorescence resonance energy transfer(FRET)biosensor based on core-shell upconversion nanoparticle(csUCNP)and gold nanoparticle(AuNP)for accurate detection of SARS-CoV-2 viral RNA is presented.In this biodetection assay,the Tm^(3+)/Er^(3+)co-doped csUCNP NaGdF_(4):Yb/Tm@NaYF_(4):Yb/Er acts as an energy donor and AuNP serves as an energy acceptor.The upconversion emission of Tm^(3+)and the design of the core-shell structure led to a simultaneous surface plasmon effect of AuNP.The localized surface plasmon resonance(LSPR)arising from collective oscillations of free electrons significantly enhanced FRET efficiency between Er^(3+)and AuNP.The as-prepared biosensor obtained a limit of detection(LOD)as low as 750 aM,indicating that the integration of FRET and surface plasmon into one biodetection assay significantly boosted the sensitivity of the biosensor.In addition,samples extracted from clinical samples are also utilized to validate the effectiveness of the biosensor.Therefore,this innovative plasmon-enhanced FRET biosensor based on Tm^(3+)/Er^(3+)co-doped csUCNP may pave the way for rapid and accurate biodetection applications.展开更多
In the quest for optimizing biodegradable implants,the exploration of piezoelectric materials stands at the forefront of biomedical engineering research.Traditional piezoelectric materials often suffer from limitation...In the quest for optimizing biodegradable implants,the exploration of piezoelectric materials stands at the forefront of biomedical engineering research.Traditional piezoelectric materials often suffer from limitations in biocompatibility and biodegradability,significantly impeding their in vivo study and further biomedical application.By leveraging molecular engineering and structural design,a recent innovative approach transcends the conventional piezoelectric limits of the molecules designed for biodegradable implants.The biodegradable molecular piezoelectric implants may open new avenues for their applications in bioenergy harvesting/sensing,implanted electronics,transient medical devices and tissue regeneration.展开更多
基金financially supported by the Natural Science Foundation of Guangdong Province(No.2024A1515010639)PolyU Postdoc Matching Fund Scheme(No.1-W327),PolyU Grant(No.1-CE0H)+3 种基金Shenzhen Science and Technology Program(No.ZDSYS20220606100406016)Shenzhen Key Laboratory of Photonics and Biophotonics(No.ZDSYS20210623092006020)National Key Laboratory of Green and Long-Life Road Engineering in Extreme Environment(Shenzhen)(No.868-000003010103)National Natural Science Foundation of China(No.52208272)。
文摘Fueled by the increasing imperative for sustainable energy solutions and the burgeoning emphasis on health awareness,self-powered techniques have undergone notable strides in advancement.Triboelectric nanogenerators(TENGs)stand out as a prominent device capitalizing on the principles of triboelectrification and electrostatic induction to generate electricity or electrical signals.In efforts to augment the electrical output performance of TENGs and broaden their range of applications,researchers have endeavored to refine materials,surface morphology,and structural design.Among them,physical morphological modifications play a pivotal role in enhancing the electrical properties of TENGs by increasing the contact surface area,which can be achieved by building micro-/nano-structures on the surface or inside the friction material.In this review,we summarize the common morphologies of TENGs,categorize the morphologies into surface and internal structures,and elucidate their roles in enhancing the electric output performance of devices.Moreover,we systematically classify the methodologies employed for morphological preparation into physical and chemical approaches,thereby furnishing a comprehensive survey of the diverse techniques.Subsequently,typical applications of TENGs with special morphology divided by energy harvesting and self-powered sensors are presented.Finally,an overview of the challenges and future trajectories pertinent to TENGs is conducted.Through this endeavor,the aim of this article is to catalyze the evolution of further strategies for enhancing performance of TENGs.
基金financial support provided by the National Natural Science Foundation of China (52472304)。
文摘The electrochemical CO_(2) reduction reaction(eCO_(2)RR),producing gaseous C_(2+)products such as ethylene(C_(2)H_(4)),represents a sustainable strategy to mitigate the greenhouse effect.Inspired by the promotion effect of the cyano group(-C≡N) for C-C coupling in organic chemistry,several cyano-containing organocatalysts have been found to be capable of directly converting CO_(2) into C_(2)H_(4) with-C≡N as the active center during the eCO_(2)RR.The selectivity of C_(2)H_(4) for the representative catalyst,metal-free dicyandiamide(DCD),reached 27.6 % after partial hydrogenation in KHCO_(3) solution.In addition,its selectivity can be further improved to 57.7 % when coupled with oriented Cu crystals.The experimental and computational results collectively reveal that charge redistribution between Cu{100} and DCD promotes the partial hydrogenation of the cyano group and lays the foundation for the reduced energy barrier for the CO_(2) reduction on-C≡N.This study breaks the limitations of traditional metal/metal oxide-based catalysts by using cyano-containing organocatalysts for direct C_(2+) product generation,expanding the eCO_(2)RR catalyst library.In addition,this research elucidates the role of charge redistribution and cyano group hydrogenation in lowering reaction barriers,providing fundamental guidance for the design of new organocatalysts.
基金support provided by the National Natural Science Foundation of China(No.52002324)the Hong Kong Scholars Program(Nos.XJ2021073 and PolyU YZ4V)the Research Grants Council of Hong Kong GRF(No.15303123).
文摘Stimulus-responsive actuators are novel functional devices capable of sensing external stimuli and ex-hibiting specific deformation responses.MXene,owing to its unique 2D structure and efficient energy conversion efficiency,has bridged the gap in traditional devices and shown great potential for multiple stimulus-responsive actuators.However,the drawbacks of pure MXene films,including susceptibility to oxidation and vulnerability to shear stress,hinder their applications.Through composite modification and structural design strategies,a three-layer structured MXene-carbon nanotubes hybrid film(tHCM)is fabri-cated,exhibiting a tensile strength and fracture strain of 153.8 MPa and 4.65%,respectively,representing improvements of 598.4%and 226.8%compared to the initial film.Meanwhile,the film maintains excel-lent stability demonstrating the enhancing effects of hydrogen bonds and densely packed structure.The hybrid films demonstrate unique and facile welding features due to splicing properties,enabling the for-mation of complex configurations.In terms of electro-/photo-thermal conversion performance,the hybrid film can reach a reasonably high temperature of 250℃at low voltage(2.5 V)and 110.6℃under 150 mW cm^(-2) infrared light.Leveraging the thermal expansion mismatch between tHCM and thermoplastic films,an integrated,flexible,and weldable actuator with unique electro/photo-response is developed,and vari-ous biomimetic driving applications,particularly,the light-mediated hierarchical transmission and precise motion along predetermined trajectory are realized.This work not only provides an effective strategy for modifying MXene composite films but also advances the design of novel actuators,offering broad appli-cation prospects in fields such as stimulus-responsive actuated robots and cargo transportation.
基金supported by grants from the Research Grants Council of the Hong Kong Special Administrative Region,China(Project No.CRF No.PolyU C5110-20G)PolyU Grants(1-CE0H,1-W30M,1-CD4S).
文摘Realizing the point-of-care tumor markers biodetection with good convenience and high sensitivity possesses great significance for prompting cancer monitoring and screening in biomedical study field.Herein,the quantum dots luminescence and microfluidic biochip with machine vision algorithm-based intelligent biosensing platform have been designed and manufactured for point-of-care tumor markers diagnostics.The employed quantum dots with excellent photoluminescent performance are modified with specific antibody as the optical labeling agents for the designed sandwich structure immunoassay.The corresponding biosensing investigations of the designed biodetection platform illustrate several advantages involving high sensitivity(~0.021 ng mL^(−1)),outstanding accessibility,and great integrability.Moreover,related test results of human-sourced artificial saliva samples demonstrate better detection capabilities compared with commercially utilized rapid test strips.Combining these infusive abilities,our elaborate biosensing platform is expected to exhibit potential applications for the future point-of-care tumor markers diagnostic area.
文摘Sr2SiO4: Eu phosphor for white light emitting diodes (LEDs) was synthesized by employing an as-prepared (Sr, Eu)CO3@SiO2 core-shell precursor as starting materials, and the effect of the core-shell precursor was also discussed on the crystal structure, particle morphology and luminescent properties of the resultant phosphor. The results showed that the hybrid β- and α′-Sr2SiO4: Eu phosphor with fine particle size and narrow distribution could be obtained at a lower firing temperature than that in conventional solidstate reaction method, and its formation mechanism was deduced to be (Sr, Eu)CO3 diffusion controlled reaction process. Responded to its hybrid crystal structure, this phosphor exhibited the combined luminescence of β- and α′-Sr2SiO4: Eu.
文摘Adenoid basal carcinoma(ABC)of the cervix is a rare and low-incidence low-grade cervical cancer.In our practice,we encountered a case of cervical ABC with squamous differentiation and high-grade squamous intraepithelial lesion(HSIL)with gland involvement in the peripheral cervix.Reviewing relevant literature and analyzing its clinical manifestations,pathological morphology,and immunohistochemical characteristics would help deepen the understanding of this malignant tumor,so as to make a comprehensive diagnosis with differential diagnosis and prevent misdiagnosis.
基金supported by the Research Grants Council of Hong Kong(RGC GRF No.15304224,PolyU SRFS2122-5S02,AoE/P-701/20)PolyU Project of 1-YWBG and RCNN 1-CE0H.
文摘The persistent pursuit of miniaturization and energy efficiency in semiconductor technology has driven the scaling of complementary metal-oxide-semiconductor field-effect transistors(CMOS FETs,i.e.,the MOSFETs)to their physical limits.Conventional MOSFETs face intrinsic challenges,especially the Boltzmann limit that imposes a fundamental lower bound on the subthreshold swing(SS≥60 mV dec^(−1)at room temperature).This limitation severely restricts voltage scaling and exacerbates static power dissipation.To overcome these bottlenecks,tunnel field-effect transistors(TFETs)have emerged as a promising post-CMOS alternative.The advantages of ultra-small SS well below the Boltzmann limit,as well as ultralow leakage currents,make TFETs ideal for low-power electronics and energy-efficient computing in the future information industry.However,its current development has encountered significant resistance to further performance improvement requirements;new breakthroughs have evolved to be based on interdisciplinary research that covers materials science,device technology,theoretical physics,and so on.Here,we provide a review on the design and development of TFET,which mainly describes the device physics model of tunnel junctions,and discusses the optimization direction of key parameters,the design direction of potential structures,and the development direction of the innovation system based on the device physics.Also,we visualize the framework for the figures of merit of TFET performance and further forecast the future applications of TFET.
基金supported by a grant from the Research Grants Council of Hong Kong (CRF No. PolyU C5110-20G)Poly U Grants (G-SB4G, 1-CD4S and 1-CE0H)。
文摘Persistent luminescence nanomaterials can remain luminescence when the light source is turned off,which exhibits promise in biosensor and bioimaging fields since they have the ability to completely eradicate tissue autofluorescence.Although significant progress has been made in the persistent luminescence biosensing,there is still a dearth of long-afterglow detection platform with low limit of detection(LOD)and high sensitivity.Herein,Zn_(2)GeO_(4):Mn,Cr persistently luminescent nanorods(PLNRs)with superior persistent luminescence and long afterglow time were developed.The addition of Cr^(3+)manifestly improves persistent luminescence intensity and afterglow duration through creating a deep defect trap.Then the biosensors were constructed by combining the Zn_(2)GeO_(4):Mn,Cr PLNRs-antibody and Fe_(3)O_(4) magnetic nanoparticles(MNPs)-antibody for nucleocapsid protein detection based on electrostatic attraction.The LOD value for nucleocapsid protein realizes as low as 39.82 ag/mL,which is much lower than the previously reported persistent luminescent-based biosensors.Accordingly,the low detection sensitivity is attributed to fluorescence resonance energy transfer.In addition,high specificity is also achieved.Therefore,the as-prepared Zn_(2)GeO_(4):Mn,Cr persistently luminescent materials can act as the promising candidate in biosensors applications.This strategy provides effective guidance for the development of biosensing platforms with high sensitivity and specificity.
文摘The aggregation ofα-synuclein(ɑ-syn)coupled with overexpressed neuroinflammation instigates the degeneration of dopaminergic neurons,thereby aggravating the progression of Parkinson’s disease(PD).Herein,we introduced a series of hydrophobic amino acid-based carbon dots(CDs)for inhibitingɑ-syn aggregation and mitigating the inflammation in PD neurons.Significantly,we show that phenylalanine CDs(Phe-CDs)could strongly bind withɑ-syn monomers and dimers via hydrophobic force,maintain their stability,and inhibit their further aggregation in situ and in vitro,finally conferring neuroprotection in PD by rescuing synaptic loss,ameliorating mitochondrial dysfunctions,and modulating Ca^(2+)flux.Importantly,Phe-CDs demonstrate the ability to penetrate the blood-brain barrier,significantly improving motor performance in PD mice.Our findings suggest that Phe-CDs hold great promise as a therapeutic agent for PD and the related neurodegenerative disease.
基金supported by the grants from the National Natural Science Foundation of China(No.62474118,52233014,and 62411560160)the Sichuan Science and Technology Program(No.2022ZYD0041)the PolyU grants(1-W22S and 1-CE0H).
文摘Designing new materials with high-performance resistive switching(RS)behaviors and/or developing alternative means to modulate the RS behaviors are of great significance for information storage and neuromorphic computing.Herein,we present a novel strategy to design and synthesize furan-annulated naphthalenes for high-performance digital and analog RS behaviors through controlling substituents.By introducing an electron acceptor of trifluoromethyl on the phenyl ring,3-phenyl-4-(4-trifluoromethylphenyl)-2H-naphtho[1,8-bc]furan(TPNF)is synthesized with donor–acceptor(D–A)pairs by utilizing the electron donor of furyl in the naphthalene.Owing to the constructed D–A systems where electrons can be transported under the external bias voltage,the prepared TPNF thin films demonstrate high-performance bipolar digital RS behaviors with multilevel storage characteristics.On the other hand,if the substituent on the phenyl ring is replaced by an electron donor of methoxy,4-(4-methoxyphenyl)-3-phenyl-2H-naphtho[1,8-bc]furan(MPNF)can be constructed with only electron-donor units of furyl and methoxy.The fabricated MPNF thin films show analog RS behaviors owing to the carrier trapping/detrapping from the nucleophilic trapping sites generated from the electron-donor units.The analog memristors demonstrate synaptic functions with high linearity of conductance modulation,which is highly desirable for neuromorphic computing.Such synaptic memristors based on MPNF are completely capable of recognizing digit images with high accuracy(95.2%)and implementing decimal arithmetic of addition,subtraction,multiplication,and division operations.This study provides a feasible way to modulate the RS properties by the strategy of introducing different substituents,demonstrating promising applications of such well-designed organic semiconductors for multilevel storage and neuromorphic computing.
基金supported by the National Natural Science Foundation of China(Grant 52002133).
文摘The aggregation ofα-synuclein(ɑ-syn)coupled with overexpressed neuroinflammation instigates the degeneration of dopaminer-gic neurons,thereby aggravating the progression of Parkinson’s disease(PD).Herein,we introduced a series of hydrophobic amino acid–based carbon dots(CDs)for inhibitingɑ-syn aggregation and mitigating the inflammation in PD neurons.Significantly,we show phenylalanine CDs(Phe-CDs)could strongly bind withɑ-syn monomers and dimers via hydrophobic force,maintain their stability,and inhibit their further aggregates in situ and in vitro,finally conferring neuroprotection in PD by rescuing synaptic loss,ameliorating mitochondrial dysfunctions,and modulating Ca^(2+) flux.Importantly,Phe-CDs demonstrate the ability to penetrate the blood–brain barrier(BBB),significantly improving motor performance in PD mice.Our findings suggest that Phe-CDs hold great promise as a therapeutic agent for PD and the relative neurodegenerative disease.
基金the Research Grants Council of Hong Kong(GRF no.15303123)Research Grants Council of Hong Kong(PolyU SRFS 2122-5S02)+1 种基金PolyU Projects of the Research Centre for Nanoscience and Nanotechnology(RCNN)and the Photonics Research Institute(PRI)(1-CE0H and 1-CD6X)Open Access funding provided by The Hong Kong Polytechnic University。
文摘MXene exhibits notable piezoelectric properties,making it a promising material for high-performance piezoelectric nanogenerators(PENGs)in next-generation smart wearable devices and bioelectronics.However,current MXene-based PENGs face challenges such as insufficient mechanical robustness,low piezoelectric response,and limited long-term functionality.These limitations primarily stem from the small effective area and low strain levels of MXene nanosheets.Here,we constructed a high-entropy TiVCrMoC3Tx MXene composite film by leveraging strong hydrogen bonding interactions between MXene and polyvinyl alcohol(PVA),which was further developed into a self-powered flexible nanogenerator.The resulting device exhibited a significant piezoresponse with output signals of 500 mV and 790 pA under a compressive force of 3.47 N,along with considerable long-term functionality over 1500 cycles.Moreover,a hydrofluoric-free etching approach was employed to synthesize the high-entropy MXene nanosheets,which ensures the safety and biocompatibility for bioelectronics applications.This work highlights the potential of high-entropy MXene for sustainable applications in wearable electronics and energy harvesting.
基金This work was supported by the grants from Research Grants Council of Hong Kong CRF No.C7036-17WGRF No.PolyU 153033/17PPolyU Grant No.G-UABC.
文摘Ever since discovery of graphene,two-dimensional(2D)materials become a new tool box for information technology.Among the 2D family,ultrathin bismuth(Bi)has attracted a great deal of attention in recent years due to its unique topological insulating properties and large magnetoresistance.However,the scalable synthesis of layered Bi ultrathin films is rarely been reported,which would greatly restrict further fundamental investigation and practical device development.Here,we demonstrate the direct growth of homogeneous and centimeter-scale layered Bi films by pulsed laser deposition(PLD)technique.The as-grown Bi film exhibits high-purity phase and good crystallinity.In addition,both(111)and(110)-oriented Bi films can be synthesized by precisely controlling the processing temperature.The characterization of optical properties shows a thickness dependent band gaps(0.075-0.2 eV).Moreover,Bi thin-film-based field-effect transistors have been demonstrated,exhibiting a large carrier mobility of 220 cm2 V−1 s−1.Our work suggests that the PLD-grown Bi films would hold the potential to develop spintronic applications,electronic and optoelectronic devices used for information science and technology.
基金the grant from Research Grants Council of Hong Kong(GRF No.PolyU 153033/17P).
文摘Two-dimensional(2D)ferroelectric materials with unique structure and extraordinary optoelectrical properties have attracted intensive research in the field of nanoelectronic and optoelectronic devices,such as optical sensors,transistors,photovoltaics and non-volatile memory devices.However,the transition temperature of the reported ferroelectrics in 2D limit is generally low or slightly above room temperature,hampering their applications in high-temperature electronic devices.Here,we report the robust high-temperature ferroelectricity in 2D a-In2Se3,grown by chemical vapor depostion(CVD),exhibiting an out-of-plane spontaneous polarization reaching above 200℃.The polarization switching and ferroelectric domains are observed in In2Se;nanoflakes in a wide temperature range.The coercive field of the CVD grown ferroelectric layers ilustrates a room-temperature thickness dependency and increases drastically when the film thickness decreases;whereas there is no large variance in the coercive field at dfterent termperature from the samples with identical thickness.The results show the stable ferroelectricit of In2Se3 nanoflakes maintained at high temperature and open up the opportunities of 2D materials for novel applications in high-temperature nanoelectronic devices.
基金the National Natural Science Foundation of China (61705214)the Research Grants Council-General Research Fund of Hong Kong (RGC GRF PolyU 153281/16P)
文摘Lanthanide ions have attracted great attention due to their distinct photonic properties.The optoelectronic properties and device performance are greatly affected by the interfacial coupling between the layered van der Waals heterostructure,fabricated with two or more transition metal dichalcogenide(TMD)layers.In this work,lanthanide-doped WS2/MoS2 layered heterostructures have been constructed through two synthesis steps.The doped thin films are highly textured nanosheets on wafers.Importantly,the as-prepared heterostructure exhibits efficient near-infrared emission in the range of the telecommunication window,owing to energy transfer between lanthanide ions in the two TMD layers.The use of the layered heterostructure allows the decrease of deleterious cross-relaxation due to homogeneous doping or concentration quenching.The energy transfer process was further elaborated in this work.The results suggest that lanthanide ions can effectively extend the emission band of TMD thin films and their heterostructures.The doped TMD heterostructure is highly favourable for constructing atomically thin near-infrared photonic devices.
基金support by the Hong Kong Research Grants Council(GRF Grant No.15301414)the support by the Ministry of Education,Youth and Sports of the Czech Republic under project CEITEC 2020(LQ1601)+2 种基金the Hong Kong Polytechnic Universitythe financial support by the NSFC(Nos.U1305244,21325104,11304314)the CAS/SAFEA International Partnership Program for Creative Research Teams.
文摘Lanthanide-doped upconversion nanocrystals(UCNCs)have recently become an attractive nonlinear fluorescence material for use in bioimaging because of their tunable spectral characteristics and exceptional photostability.Plasmonic materials are often introduced into the vicinity of UCNCs to increase their emission intensity by means of enlarging the absorption cross-section and accelerating the radiative decay rate.Moreover,plasmonic nanostructures(e.g.,gold nanorods,GNRs)can also influence the polarization state of the UC fluorescence—an effect that is of fundamental importance for fluorescence polarization-based imaging methods yet has not been discussed previously.To study this effect,we synthesized GNR@SiO_(2)@CaF2:Yb^(3+),Er^(3+)hybrid core–shell–satellite nanostructures with precise control over the thickness of the SiO_(2) shell.We evaluated the shell thicknessdependent plasmonic enhancement of the emission intensity in ensemble and studied the plasmonic modulation of the emission polarization at the single-particle level.The hybrid plasmonic UC nanostructures with an optimal shell thickness exhibit an improved bioimaging performance compared with bare UCNCs,and we observed a polarized nature of the light at both UC emission bands,which stems from the relationship between the excitation polarization and GNR orientation.We used electrodynamic simulations combined with Förster resonance energy transfer theory to fully explain the observed effect.Our results provide extensive insights into how the coherent interaction between the emission dipoles of UCNCs and the plasmonic dipoles of the GNR determines the emission polarization state in various situations and thus open the way to the accurate control of the UC emission anisotropy for a wide range of bioimaging and biosensing applications.
基金the financial support from the National Natural Science Foundation of China(No.52233014,12074044,11874230,12274243)the Research Grants Council of Hong Kong(PolyU SRFS2122-5S02)+1 种基金the Fund of State Key Laboratory of Information Photonics and Optical Communications(IPOC2021ZT05,IPOC2022A02)the Fundamental Research Funds for the Central Universities(BUPT).
文摘Modulation of light underpins a central part of modern optoelectronics.Con-ventional optical modulators based on refractive-index and absorption varia-tion in the presence of an electric field serve as the workhorse for diverse photonic technologies.However,these approaches based on electro-refraction or electro-absorption effect impose limitations on frequency converting and signal amplification.Lanthanide-activated phosphors offer a promising plat-form for nonlinear frequency conversion with an abundant spectrum.Here,we propose a novel approach to achieve frequency conversion and digital modula-tion of light signal by coupling lanthanide luminescence with an electrically responsive ferroelectric host.The technological benefits of such paradigm-shifting solution are highlighted by demonstrating a quasi-continuous and enhancement of the lanthanide luminescence.The ability to locally manipulate light emission can convert digital information signals into visible waveforms,and visualize electrical logic and arithmetic operations.The proof-of-concept device exhibits perspectives for developing light-compatible logic functions.These results pave the way to design more controllable lanthanide photonics with desired opto-electronic coupling.
基金This study was in part supported by the National Natural Science Foundation of China(21371106,51402167).
文摘In this article,the biodegradation process and bone formation of a mineralized collagen reconstruction rod embedding in necrosis of human femoral head were investigated by imageological and histological methods.Computed radiography(CR)computerized tomography(CT),common pathological section and hard tissue section analysis were used to evaluated the dynamics of imageological and histopathological changes of femoral head,interface between the host bone and implant and the bone reconstruction process.The results showed that the density of rods increased closed to that of host bones after 1 year implanting,and the interface between them turns to blurring.Hard tissue grinding sections analysis showed osteocytes appearing in sparse bone trabecular and bone pit region,as well as a few vessels in the degraded dye powder matrix were noticed,indicating the new bone forming between the implants and host bones.Regular decalcified sections analysis showed scattered osteoclasts,multinucleated giant cells and fibrosis components existing in the degraded rod and the host bone trabecular.Degraded debris was endocytosed by giant cells,and vascular network formed around the boundaries of the implanted rod.The good osteointegration has been expressed by the interface between the implanted rod and the host bone becoming blurred.Histological results indicated that the implanted rod degradation process and new bones regeneration simultaneously occurred around the boundaries of embedding rod.New bone and host bone were hinged and co-existed.
基金Research Grants Council of the Hong Kong Special Administrative Region,China,Grant/Award Number:C5110-20GFPolyU Internal Research Fund,Grant/Award Numbers:1-CD4S,1-W21GShenzhen-Hong Kong-Macao Technology Research Programme Fund,Grant/Award Number:SGDX2020110309260000。
文摘Outbreaks of infectious viruses offer a formidable challenge to public healthcare systems and early detection of viruses is essential for preventing virus propagation.In this work,an ultrasensitive plasmon-enhanced fluorescence resonance energy transfer(FRET)biosensor based on core-shell upconversion nanoparticle(csUCNP)and gold nanoparticle(AuNP)for accurate detection of SARS-CoV-2 viral RNA is presented.In this biodetection assay,the Tm^(3+)/Er^(3+)co-doped csUCNP NaGdF_(4):Yb/Tm@NaYF_(4):Yb/Er acts as an energy donor and AuNP serves as an energy acceptor.The upconversion emission of Tm^(3+)and the design of the core-shell structure led to a simultaneous surface plasmon effect of AuNP.The localized surface plasmon resonance(LSPR)arising from collective oscillations of free electrons significantly enhanced FRET efficiency between Er^(3+)and AuNP.The as-prepared biosensor obtained a limit of detection(LOD)as low as 750 aM,indicating that the integration of FRET and surface plasmon into one biodetection assay significantly boosted the sensitivity of the biosensor.In addition,samples extracted from clinical samples are also utilized to validate the effectiveness of the biosensor.Therefore,this innovative plasmon-enhanced FRET biosensor based on Tm^(3+)/Er^(3+)co-doped csUCNP may pave the way for rapid and accurate biodetection applications.
基金Taishan Scholars Program of Shandong Province,Grant/Award Number:tsqn201909180。
文摘In the quest for optimizing biodegradable implants,the exploration of piezoelectric materials stands at the forefront of biomedical engineering research.Traditional piezoelectric materials often suffer from limitations in biocompatibility and biodegradability,significantly impeding their in vivo study and further biomedical application.By leveraging molecular engineering and structural design,a recent innovative approach transcends the conventional piezoelectric limits of the molecules designed for biodegradable implants.The biodegradable molecular piezoelectric implants may open new avenues for their applications in bioenergy harvesting/sensing,implanted electronics,transient medical devices and tissue regeneration.
