Traditional Chinese Medicine(TCM)is one of the most promising programs for disease prevention and treatment.Meanwhile,the quality of TCM has garnered much attention.To ensure the quality of TCM,many works are based on...Traditional Chinese Medicine(TCM)is one of the most promising programs for disease prevention and treatment.Meanwhile,the quality of TCM has garnered much attention.To ensure the quality of TCM,many works are based on the blockchain scheme to design the traceability scheme of TCM to trace its origin.Although these schemes can ensure the integrity,sharability,credibility,and immutability of TCM more effectively,many problems are exposed with the rapid growth of TCM data in blockchains,such as expensive overhead,performance bottlenecks,and the traditional blockchain architecture is unsuitable for TCM data with dynamic growth.Motivated by the aforementioned problems,we propose a novel and lightweight TCM traceability architecture based on the blockchain using sharding(LBS-TCM).Compared to the existing blockchain-based TCM traceability system,our architecture utilizes sharding to develop a novel traceability mechanism that supports more convenient traceability operations for TCM requirements such as uploading,querying,and downloading.Specifically,our architecture consists of a leader shard blockchain layer as its main component,which employs a sharding mechanism to conveniently TCM tracing.Empirical evaluations demonstrated that our architecture showed better performance in many aspects compared to traditional blockchain architectures,such as TCM transaction processing,TCM transaction querying,TCM uploading,etc.In our architecture,tracing TCM has become a very efficient operation,which ensures the quality of TCM and provides great convenience for subsequent TCM analysis and retrospective research.展开更多
Randomized controlled trials(RCTs)provide optimal evidence of the effectiveness and safety of a new drug,a new medical device,or a new therapeutic strategy with the necessary scientific design[1].Traditional electroni...Randomized controlled trials(RCTs)provide optimal evidence of the effectiveness and safety of a new drug,a new medical device,or a new therapeutic strategy with the necessary scientific design[1].Traditional electronic data collection(EDC)systems for clinical trials primarily focus on data entry,validation,and compliance monitoring.However,their reliance on centralized architectures introduces vulnerabilities in data security and integrity。展开更多
基金supported by the research and innovation program for graduate students of the Guangzhou University of Traditional Chinese MedicineThis work is also partially supported by the National Key Research and Development Program of China(2019YFC1710402)the research on tracing TCM Electronic Medical Records Based on the Lightweight Blockchain of Guangdong Provincial Bureau of Traditional Chinese Medicine(20222045).
文摘Traditional Chinese Medicine(TCM)is one of the most promising programs for disease prevention and treatment.Meanwhile,the quality of TCM has garnered much attention.To ensure the quality of TCM,many works are based on the blockchain scheme to design the traceability scheme of TCM to trace its origin.Although these schemes can ensure the integrity,sharability,credibility,and immutability of TCM more effectively,many problems are exposed with the rapid growth of TCM data in blockchains,such as expensive overhead,performance bottlenecks,and the traditional blockchain architecture is unsuitable for TCM data with dynamic growth.Motivated by the aforementioned problems,we propose a novel and lightweight TCM traceability architecture based on the blockchain using sharding(LBS-TCM).Compared to the existing blockchain-based TCM traceability system,our architecture utilizes sharding to develop a novel traceability mechanism that supports more convenient traceability operations for TCM requirements such as uploading,querying,and downloading.Specifically,our architecture consists of a leader shard blockchain layer as its main component,which employs a sharding mechanism to conveniently TCM tracing.Empirical evaluations demonstrated that our architecture showed better performance in many aspects compared to traditional blockchain architectures,such as TCM transaction processing,TCM transaction querying,TCM uploading,etc.In our architecture,tracing TCM has become a very efficient operation,which ensures the quality of TCM and provides great convenience for subsequent TCM analysis and retrospective research.
基金supported by the National Natural Science Foundation of China(92368205 and 82301265)the Guangdong Provincial Natural Science Foundation for Progressive Young Scholars(2023A1515030170)+3 种基金the Science and Technology Planning Projects of Guangdong Province(2018B010109008)the Science and Technology Planning Project of the Guangzhou Municipal Health Commission(2024A031004)the Basic Scientific Research Projects of Sun Yat-sen University(23ykcxqt002)the China Postdoctoral Science Foundation(2023M734047).
文摘Randomized controlled trials(RCTs)provide optimal evidence of the effectiveness and safety of a new drug,a new medical device,or a new therapeutic strategy with the necessary scientific design[1].Traditional electronic data collection(EDC)systems for clinical trials primarily focus on data entry,validation,and compliance monitoring.However,their reliance on centralized architectures introduces vulnerabilities in data security and integrity。
