Background:Prostate cancer,a prevalent malignancy in men,often results in erectile dysfunction(ED),particularly following treatments like radical prostatectomy(RP)and radiotherapy,significantly affecting quality of li...Background:Prostate cancer,a prevalent malignancy in men,often results in erectile dysfunction(ED),particularly following treatments like radical prostatectomy(RP)and radiotherapy,significantly affecting quality of life.Managing ED in prostate cancer survivors is critical.Inflatable penile prosthesis(IPP)implantation is a well-established treatment for ED,yet the literature on satisfaction rates for patients with a history of androgen deprivation therapy(ADT)remains sparse.We aimed to investigate the impact of ADT on satisfaction rates in patients undergoing IPP implantation following RP or radiation therapy(XRT).Methods:A retrospective review of 529 patient charts identified 96 eligible patients who underwent IPP implantation post-prostate cancer treatment and completed the 11-item Erectile Dysfunction Inventory of Treatment Satisfaction(EDITS)questionnaire.Patients were stratified into two groups based on ADT status,and their satisfaction scores were compared.Effect sizes were used to assess clinical relevance alongside statistical significance(p=0.0344).Results:Patients receiving ADT had significantly lower EDITS scores(p=0.0344)compared to those not on ADT.RP patients reported higher satisfaction post-IPP compared to XRT patients,even after controlling for ADT.Additionally,coronary artery disease(CAD)was associated with lower satisfaction scores.Conclusion:ADT significantly lowers patient satisfaction post-IPP,with RP patients generally reporting higher satisfaction than XRT patients.These findings highlight the importance of counseling prostate cancer patients on ADT's impact on long-term sexual satisfaction and suggest areas for further research to enhance outcomes.展开更多
文摘Background:Prostate cancer,a prevalent malignancy in men,often results in erectile dysfunction(ED),particularly following treatments like radical prostatectomy(RP)and radiotherapy,significantly affecting quality of life.Managing ED in prostate cancer survivors is critical.Inflatable penile prosthesis(IPP)implantation is a well-established treatment for ED,yet the literature on satisfaction rates for patients with a history of androgen deprivation therapy(ADT)remains sparse.We aimed to investigate the impact of ADT on satisfaction rates in patients undergoing IPP implantation following RP or radiation therapy(XRT).Methods:A retrospective review of 529 patient charts identified 96 eligible patients who underwent IPP implantation post-prostate cancer treatment and completed the 11-item Erectile Dysfunction Inventory of Treatment Satisfaction(EDITS)questionnaire.Patients were stratified into two groups based on ADT status,and their satisfaction scores were compared.Effect sizes were used to assess clinical relevance alongside statistical significance(p=0.0344).Results:Patients receiving ADT had significantly lower EDITS scores(p=0.0344)compared to those not on ADT.RP patients reported higher satisfaction post-IPP compared to XRT patients,even after controlling for ADT.Additionally,coronary artery disease(CAD)was associated with lower satisfaction scores.Conclusion:ADT significantly lowers patient satisfaction post-IPP,with RP patients generally reporting higher satisfaction than XRT patients.These findings highlight the importance of counseling prostate cancer patients on ADT's impact on long-term sexual satisfaction and suggest areas for further research to enhance outcomes.
