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Use of neuron-specific enolase to predict mild brain injury in motorcycle crash patients with maxillofacial fractures:A pilot study 被引量:20
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作者 Muhammad Ruslin jan wolff +3 位作者 Harmas Yazid Yusuf Muhammad Zaifullah Arifin Paolo Boffano Tymour Forouzanfar 《Chinese Journal of Traumatology》 CAS CSCD 2019年第1期47-50,共4页
Purpose:Mild traumatic brain injury(TBI)is common but accurate diagnosis and its clinical consequences have been a problem.Maxillofacial trauma does have an association with TBI.Neuron-specific enolase(NSE)has been de... Purpose:Mild traumatic brain injury(TBI)is common but accurate diagnosis and its clinical consequences have been a problem.Maxillofacial trauma does have an association with TBI.Neuron-specific enolase(NSE)has been developed to evaluate neuronl damage.The objective of this study was to investigate the accuracy of NSE serum levels to detect mild brain injury of patients with sustained maxillofacial fractures during motor vehicle accidents.Methods:Blood samples were drawn from 40 healthy people(control group)and 48 trauma patients who has sustained isolated maxillofacial fractures and mild brain injury in motor vehicle accidents.Brain injuries were graded by Glasgow Coma Scale.In the trauma group,correlations between the NSE serum value and different facial fracture sites were also assessed.Results:The NSE serum level(mean±SD,ng/ml)in the 48 patients with maxillofacial fractures and mild TBI was 13.12±9.68,significantly higher than that measured in the healthy control group(7.72±1.82,p<0.001).The mean NSE serum level(ng/ml)in the lower part of the facial skeleton(15.44 with SD 15.34)was higher than that in the upper facial part(12.42 with SD 7.68);and the mean NSE level(ng/ml)in the middle-and lower part(11.97 with SD 5.63)was higher than in the middle part(7.88 with SD 2.64).Conclusion:An increase in NSE serum levels can be observed in patients sustained maxillofacial fractures and mild brain injury. 展开更多
关键词 Neuron-specific enolase SERUM Maxillofacial fractures Mild brain injuries
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3D printing of patient-specific neck splints for the treatment of post-burn neck contractures 被引量:1
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作者 Dafydd O.Visscher Sjoerd te Slaa +5 位作者 Marielle E.Jaspers Marloes van de Hulsbeek Jorien Borst jan wolff Tymour Forouzanfar Paul P.van Zuijlen 《Burns & Trauma》 2018年第2期155-157,共3页
Dear Editor,Burn scar contracture is a common problem in healing burn wounds of the neck. It can cause both pain and dysfunction if not treated adequately (1)The treatment of such wounds often involves a combination o... Dear Editor,Burn scar contracture is a common problem in healing burn wounds of the neck. It can cause both pain and dysfunction if not treated adequately (1)The treatment of such wounds often involves a combination of surgery and splinting therapy (2)A variety of splints, including the thermoplastic static neck splint [3], the Watusi collar [4], manually fabricated splints, and pre-fabricated splints such as the Philadelphia collar have been used for the management of scar contractures. However, each type of splint has its own advantages and disadvantages, and none of these splints seem to reduce the need for skin reconstruction nor delays the time until surgical re-construction [5]. 展开更多
关键词 NECK BURNS CONTRACTURE 3D printing NECK SPLINT Clinical Optical 3D scanning
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