Opuntia:(Cactaceae)species grow in arid and semi-arid regions around the globe.They grow in the wild but they are also cultivated and constitute an underestimated source of nutrients and functional compounds for human...Opuntia:(Cactaceae)species grow in arid and semi-arid regions around the globe.They grow in the wild but they are also cultivated and constitute an underestimated source of nutrients and functional compounds for human consumption and animal feed.The polyphenol composition and bioactivity of the fruits of six Opuntia that grow and/or are cultivated in Mexico have been investigated.These are O.ficus-indica,O.albicarpa,O.megacantha,O.undulata,O.robusta and O.joconostle.Protocatechuic,gallic,sinapic and ferulic acids were the most abundant polyphenols.The samples exhibited high antioxidant activity as assessed using the DPPH and ABTS radical scavenging assays,and also in Caco-2 cells exposed to the ABAP radical.The samples also inhibited proliferation of the Caco-2 and THP-1 cell lines,and the production of nitric oxide by RAW 246.7 cells.These activities indicate that Mexican Opuntias represent a valuable source of bioactive components with health promoting properties,which could constitute the basis for a revaluation of these plants.展开更多
基金funded by a LINC GLOBAL project(C.S.I.C.,Spain).Project reference INCGL20002the Instituto Politécnico Nacional(IPN)for the support provided through the SIP projects 20230172,20240612,and 20250017+2 种基金the Secretaría de Ciencia,Tecnología e Innovación(SECTI)for the grant awarded to N.C.C.A.[No.892296]the Dirección de Cooperación Académica and BEIFI-IPN of IPNthe Consejo Superior de Investigaciones Científicas(CSIC)for the financial support provided and Herbario de la Escuela Nacional de Ciencias Biológicas,Instituto Politécnico Nacional(Ciudad de México,México)for the identification of the plant material.
文摘Opuntia:(Cactaceae)species grow in arid and semi-arid regions around the globe.They grow in the wild but they are also cultivated and constitute an underestimated source of nutrients and functional compounds for human consumption and animal feed.The polyphenol composition and bioactivity of the fruits of six Opuntia that grow and/or are cultivated in Mexico have been investigated.These are O.ficus-indica,O.albicarpa,O.megacantha,O.undulata,O.robusta and O.joconostle.Protocatechuic,gallic,sinapic and ferulic acids were the most abundant polyphenols.The samples exhibited high antioxidant activity as assessed using the DPPH and ABTS radical scavenging assays,and also in Caco-2 cells exposed to the ABAP radical.The samples also inhibited proliferation of the Caco-2 and THP-1 cell lines,and the production of nitric oxide by RAW 246.7 cells.These activities indicate that Mexican Opuntias represent a valuable source of bioactive components with health promoting properties,which could constitute the basis for a revaluation of these plants.
