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Antidiarrheal and phytochemical constituents of methanol extracts of some plants in Saudi Arabia
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作者 KhaledB.AlHARBi ibrahimm.el-ashmawy 《中国药理学与毒理学杂志》 CAS CSCD 北大核心 2015年第S1期112-112,共1页
OBJECTIVE The purpose of the present study was to evaluate the antidiarrheal effects and the phytochemical constituents of methanol extracts of some plants used traditionally in kingdom of Saudi Arabia using castor oi... OBJECTIVE The purpose of the present study was to evaluate the antidiarrheal effects and the phytochemical constituents of methanol extracts of some plants used traditionally in kingdom of Saudi Arabia using castor oil-induced diarrhea and gastrointestinal motility test using charcoal meal method were examined.METHODS The methanolic extracts were initially assayed for their effects in castor oil-induced diarrhea at different doses(250and 500mg·kg-1 followed by their evaluation on the peristaltic movements in charcoal meal test.RESULTS The results of the present study indicates that,administration of the following methanol plant extracts;Rhazya stricta,Heliotropium bacciferum,Tribulus longipetalus,Achillea fragrantissima,Artemisia herba alba,Haloxylon salicornicum,Plantago coronopus,Cyperus conglomerates,Hordeum distichon,Eragrostis poaeoides,Astragalus spinosus,Lepidium sativum seeds induced a higher percentages of inhibition of diarrhea.While,the administration of Rhanterium epapposum,Moltkiopsis ciliate,Lasiurus hirsutus,Deverra triradiata,Lycium shawii.Echinops spinosus,Echinops hussoni,and Prosopis farcta were the least efficacy.The antidiarrheal effects of these plants might be due to their high contents of flavonoids and tannins.CONCLUSION It could be concluded that,the remarkable antidiarrheal effects of these plants attest to their utility in a wide range of stats of diarrhea. 展开更多
关键词 ANTIDIARRHEAL DIARRHEA PLANT EXTRACTS charcoal mea
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Anti-tick activity of some methanol plant extracts indigenous in Saudi Arabia
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作者 KhaledB.Al-HARBI ibrahimm.el-ashmawy HusseinM.OMAR 《中国药理学与毒理学杂志》 CAS CSCD 北大核心 2015年第S1期112-113,共2页
OBJECTIVE Ticks are economically important parasites all over the world.They are vectors of different animal and human infectious diseases.Tick control is globally based on chemical acaricides,but the developing tick ... OBJECTIVE Ticks are economically important parasites all over the world.They are vectors of different animal and human infectious diseases.Tick control is globally based on chemical acaricides,but the developing tick resistance to most of the currently used synthetic acaricides encouraged to look for alternative ways to control ticks,especially natural products that are relatively environment friendly.METHODS An in vitro screening of the effects of some indigenous plants was carried out.Twenty-one plant species were extracted and tried to have effects on the most prevalent tick species;Hyalomma drommederi of camels.Fully engorged female ticks of the same weight,were immersed in the different extracts for 5,15,30 and 60min.RESULTS Treated ticks were revived and incubated with the control groups for daily observation of their activity and egg production.While some plant extracts have killing effects after 30-60 min exposure(Rhanterium epapposum,Achillea fragrantissima and Eragrostis poaeodes)others have stopped oviposition(Artemisia herba alba,Haloxylon salicornicum,Plantago coronopus,Moltkiopsis ciliate and Lasiurus hirsutus).Most of the extracts have reducing effect on the egg mass.Marked reduction of the egg masses associated with delayed oviposition was recorded on exposure to Lepidium sativum seeds extract.CONCLUSION The phytoconstituents were determined by a standard methods and further studies are on going to determine the bioactive components that may have the above mentioned acaricidal effects. 展开更多
关键词 TICKS Hyalomma drommederi PLANT EXTRACTS ovipositi
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