The experiment was conducted to evaluate the acute toxicity of aqueous extract of Adenium obesum stem bark in juveniles of Clarias gariepinus by assessing the hematological responses of the exposed groups compared to ...The experiment was conducted to evaluate the acute toxicity of aqueous extract of Adenium obesum stem bark in juveniles of Clarias gariepinus by assessing the hematological responses of the exposed groups compared to the control in a static non-renewal bioassay for 96 hours. The fishes (N = 180, mean weight and length 21.48 ± 3.32 g and 11.37 ± 1.23 cm) respectively were randomly distributed 10 (ten) fishes per group in triplicates constituting six experimental groups as follows;G1 (Control), G2 (6.5 mg/l), G3 (7.8 mg/l), G4 (8.5 mg/l), G5 (9.5 mg/l) and G6 (11.5 mg/l). Red blood cell (RBC) count, packed cell volume (PCV) and hemoglobin concentration were decreased significantly (P < 0.05) as opposed to the significant (P < 0.05) increase in total white blood cell count (TWBC). Thus the study concludes that aqueous extract of Adenium obesum stem bark is toxic to erythrocytes while a converse adaptive response in the white blood cells.展开更多
文摘The experiment was conducted to evaluate the acute toxicity of aqueous extract of Adenium obesum stem bark in juveniles of Clarias gariepinus by assessing the hematological responses of the exposed groups compared to the control in a static non-renewal bioassay for 96 hours. The fishes (N = 180, mean weight and length 21.48 ± 3.32 g and 11.37 ± 1.23 cm) respectively were randomly distributed 10 (ten) fishes per group in triplicates constituting six experimental groups as follows;G1 (Control), G2 (6.5 mg/l), G3 (7.8 mg/l), G4 (8.5 mg/l), G5 (9.5 mg/l) and G6 (11.5 mg/l). Red blood cell (RBC) count, packed cell volume (PCV) and hemoglobin concentration were decreased significantly (P < 0.05) as opposed to the significant (P < 0.05) increase in total white blood cell count (TWBC). Thus the study concludes that aqueous extract of Adenium obesum stem bark is toxic to erythrocytes while a converse adaptive response in the white blood cells.
