Many survival studies record the times to two or more distinct failures oneach subject. The failures may be events of different natures or may be repetitions of the same kindof event. In this article, we consider the ...Many survival studies record the times to two or more distinct failures oneach subject. The failures may be events of different natures or may be repetitions of the same kindof event. In this article, we consider the regression analysis of such multivariate failure timedata under the additive hazards model. Simple weighted estimating functions for the regressionparameters are proposed, and asymptotic distribution theory of the resulting estimators are derived.In addition, a class of generalized Wald and generalized score statistics for hypothesis testingand model selection are presented, and the asymptotic properties of these statistics are examined.展开更多
基金Supported by the National Natural Science Foundation of China (No. 10471140)Science Foundation of HUBEI (98j081)Scientific Research Great Project of Education Department of HUBEI (2002Z04001).supported by grants from Research Grants Council of
文摘Many survival studies record the times to two or more distinct failures oneach subject. The failures may be events of different natures or may be repetitions of the same kindof event. In this article, we consider the regression analysis of such multivariate failure timedata under the additive hazards model. Simple weighted estimating functions for the regressionparameters are proposed, and asymptotic distribution theory of the resulting estimators are derived.In addition, a class of generalized Wald and generalized score statistics for hypothesis testingand model selection are presented, and the asymptotic properties of these statistics are examined.