Ugi-4CC(four-component condensation) reaction is one of isonitrile-based MCR's(multicomponent reactions), which is started with an amine, an aldehyde, a carboxylic acid and an isocyanide, after full use of the spe...Ugi-4CC(four-component condensation) reaction is one of isonitrile-based MCR's(multicomponent reactions), which is started with an amine, an aldehyde, a carboxylic acid and an isocyanide, after full use of the specialty of isonitrile and be used to build a series of compounds with different structural skeletons by using diverse inputs. In our work, two kinds of isonitriles were synthesized and a parallel synthesis of an α-acylarnino amide library was performed to modify the Ugi reaction conditions.展开更多
文摘Ugi-4CC(four-component condensation) reaction is one of isonitrile-based MCR's(multicomponent reactions), which is started with an amine, an aldehyde, a carboxylic acid and an isocyanide, after full use of the specialty of isonitrile and be used to build a series of compounds with different structural skeletons by using diverse inputs. In our work, two kinds of isonitriles were synthesized and a parallel synthesis of an α-acylarnino amide library was performed to modify the Ugi reaction conditions.
