To understand the differences in the composition and sources of PM_(2.5) and PM_(10) caused by coarse particles,integrated PM_(2.5) and PM_(10) samples were synchronously collected in Nanjing,East China,in summer 2020...To understand the differences in the composition and sources of PM_(2.5) and PM_(10) caused by coarse particles,integrated PM_(2.5) and PM_(10) samples were synchronously collected in Nanjing,East China,in summer 2020 and winter 2020/2021.Bulk and molecular speciation and light absorption measurements of aerosol extractswere performed,followed by positivematrix factorization(PMF)based on the PM_(2.5) and PM_(10) data sets,respectively.The difference in average concentrations of total bulk species between PM_(2.5) and PM_(10) was mainly caused by the distribution of considerable NO_(3)^(–),SO42–,Ca^(2+),and organic carbon(OC)in coarse particles.Coarse PMinfluenced by abrasion products from tirewear and leaves contributed about half of the low-volatility n-alkanes in summer.The contribution of coarse PM to biomass burning tracers and water-soluble OC increased in winter when biomass combustion was excessively active.More than 70%of sugar polyols were attributable to coarse PM in summer,and biomass burning could be an important source in winter.The light-absorbing organic chromophores were almost entirely associated with PM_(2.5),but water-soluble organic carbon(WSOC)exhibited stronger light absorption in PM_(10) extracts than in PM_(2.5) extracts possibly due to the influence of coarse PMon pH.PMF analysis indicated that biomass burning,aqueous-phase reactions,and processed dust were the main contributors of organic matter and its light absorption in winter.Biogenic primary and secondary sources made discernable contributions only in summer.The differences between PM_(2.5) and PM_(10) were likely attributed to mixing of crustal dust,combustion particles,and surface reactions.展开更多
(±)-Talapyrones A−F(1−6),six pairs of dimeric polyketide enantiomers featuring unusual 6/6/6 and 6/6/6/5 ring systems,were isolated from the fungus Talaromyces adpressus.Their structures were determined by spectr...(±)-Talapyrones A−F(1−6),six pairs of dimeric polyketide enantiomers featuring unusual 6/6/6 and 6/6/6/5 ring systems,were isolated from the fungus Talaromyces adpressus.Their structures were determined by spectroscopic analysis and HR-ESI-MS data,and their absolute configurations were elucidated using a modified Mosher’s method and electronic circular dichroism(ECD)calculations.(±)-Talapyrones A−F(1−6)possess a 6/6/6 tricyclic skeleton,presumably formed through a Michael addition reaction between one molecule ofα-pyrone derivative and one molecule of C8 poly-β-keto chain.In addition,compounds 2/3 and 4/5 are two pairs of C-18 epimers,respectively.Putative biosynthetic pathways of 1−6 were discussed.展开更多
Renewable energy,especially solar power,is vital for mitigating global warming,while climate change also impacts solar photovoltaic potential(PVpot).This study analyzes historical(1985–2014)and future(2015–2100)clim...Renewable energy,especially solar power,is vital for mitigating global warming,while climate change also impacts solar photovoltaic potential(PVpot).This study analyzes historical(1985–2014)and future(2015–2100)climate effects on PVpot,and quantifies contributions from changed radiation,temperature,and wind speed.Historically,global PVpot increased by 0.42‰,with notable rises in eastern China(+7.1‰)and southern Europe(+3.5‰).By the end of the century,increased radiation-induced PVpot(+1.27‰)offsets temperatureinduced PVpot loss(−0.54‰)under SSP1-2.6,yielding a net PVpot increase(+0.74‰).Under SSP2-4.5,the temperature-induced PVpot decline(−1.50‰)drives the final PVpot reduction(−1.15‰).Under SSP3-7.0 and SSP5-8.5,combined radiation-induced(−1.94‰and−1.99‰)and temperature-induced PVpot changes(−2.67‰and−3.41‰)result in significant PVpot declines(−4.57‰and−5.31‰).Regional analysis reveals that eastern China(+0.7‰to+8.6‰),southern Europe(+0.3‰to+2.5‰),and Northwest South America(+0.6‰to+2.1‰)retain positive changes in future PVpot across all climate scenarios,which may be due to reduced aerosols and cloud cover,suggesting these areas can remain suitable for photovoltaic installations despite climate changes.In contrast,temperature-driven PVpot declines over the Qinghai-Tibet Plateau(−9.1‰to−4.3‰)and northern Africa(−9.3‰to−4.9‰)under future high-emission scenarios indicate that these historically advantageous regions will become less suitable for solar energy deployment.The findings underscore that climate changes driven by sustainable development pathways will generate more PVpot in the future for better global warming mitigation.展开更多
We used observed concentrations of air pollutants,reanalyzed meteorological parameters,and results from the Goddard Earth Observing System Chemical Transport Model to examine the relationships between concentrations o...We used observed concentrations of air pollutants,reanalyzed meteorological parameters,and results from the Goddard Earth Observing System Chemical Transport Model to examine the relationships between concentrations of maximum daily 8-h average ozone(MDA8 O_(3)),PM_(2.5)(particulate matter with diameter of 2.5μm or less),and PM_(2.5)components and 2-m temperature(T2)or relative humidity(RH),as well as the effectiveness of precursor emission reductions on the control of O_(3) and PM_(2.5) in Beijing–Tianjin–Hebei(BTH)under different summertime temperature and humidity conditions.Both observed(simulated)MDA8 O_(3) and PM_(2.5) concentrations increased as T2 went up,with linear trends of 4.8(3.2)ppb℃^(−1) and 1.9(1.5)μg m^(−3)℃^(−1),respectively.Model results showed that the decreases in MDA8 O_(3) from precursor emission reductions were more sensitive to T2 than to RH.Reducing a larger proportion of volatile organic compound(VOC)emissions at higher T2 was more effective for the control of summertime O_(3) in BTH.For the control of summertime PM_(2.5) in BTH,reducing nitrogen oxides(NOx)combined with a small proportion of VOCs was the best measure.The magnitude of reduction in PM_(2.5) from reducing precursor emissions was more sensitive to RH than to T2,with the best efficiency at high RH.Results from this study are helpful for formulating effective policies to tackle O_(3) and PM_(2.5) pollution in BTH.展开更多
Glutamate is an essential excitatory neurotransmitter in the brain,playing a vital role in regulating synaptic activity and maintaining the homeostasis of the cerebral environment but also serves as a central hub for ...Glutamate is an essential excitatory neurotransmitter in the brain,playing a vital role in regulating synaptic activity and maintaining the homeostasis of the cerebral environment but also serves as a central hub for neuronal injury and inflammatory responses.In various pathological conditions,such as ischemic stroke,glutamate is released and accumulates excessively in the brain,leading to heightened stimulation of neurons and excitotoxicity.This phenomenon positions glutamate as a primary inducing factor for neuronal damage following cerebral ischemia.Glutamate exerts its effects primarily through two types of receptors:ionotropic andmetabotropic glutamate receptors,both of which are extensively distributed throughout the hippocampus and cortical regions of the brain.Ionotropic receptors mediate rapid excitatory neurotransmission upon activation by glutamate;these are mainly categorized into N-methyl-D-aspartate receptors(NMDARs),α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptors(AMPARs),and kainate receptors(KARs).Conversely,metabotropic receptors function asG-protein-coupled receptors(GPCR)facilitating glutamatergic cellular effects via intracellular secondmessenger.With the comprehensive investigation of glutamate receptors and their structural characteristics,our understanding of the nerve damage and protective mechanisms associated with glutamate receptors in ischemic stroke is progressively advancing.Consequently,exploring the role of glutamate receptors and their downstream signaling pathways in cerebral ischemia can provide a robust theoretical foundation for targeted therapies aimed at treating cerebral ischemia,stroke,and related disorders.This article reviews the function of glutamate receptors and theirmediated downstreamsignal transduction pathways in the context of ischemic brain injury.展开更多
1.Background Air pollution is a global environmental problem and has serious impacts on human health,climate change,and ecological systems.From the lessons learned by developed countries,the use of various energy type...1.Background Air pollution is a global environmental problem and has serious impacts on human health,climate change,and ecological systems.From the lessons learned by developed countries,the use of various energy types can result in different types of air pollution,such as smoke from coal burning and photochemical smog from gasoline/diesel vehicle emissions.Meanwhile,in China,rapid development in the last several decades has led to a drastic increase in coal consumption and the number of vehicles;and consequently,air pollution in China is complicated by the coexistence of high concentrations of primary and secondary trace gases and aerosol particles from multiple sources.The concept of an“air pollution complex”was first proposed by Xiaoyan TANG in 1997 to characterize the complexity of the formation mechanisms of air pollution,and calls for science-based control strategies(Zhu,2005).展开更多
China has been experiencing widespread air pollution due to rapid industrialization and urbanization in recent decades.The two major concerns of ambient air quality in China are particulate matter(PM)and tropospheric ...China has been experiencing widespread air pollution due to rapid industrialization and urbanization in recent decades.The two major concerns of ambient air quality in China are particulate matter(PM)and tropospheric ozone(O3).With the implementation of air pollution prevention and control actions in the last five years,the PM pollution in China has been substantially reduced.In contrast,under the conditions of the urban air pollution complex,the elevated O3 levels in city clusters of eastern China,especially in warm seasons,have drawn increasing attention.Emissions of air pollutants and their precursors not only contribute to regional air quality,but also alter climate.Climate change in turn can change chemical processes,long-range transport,and local meteorology that influence air pollution.Compared to PM,less is known about O3 pollution and its climate effects over China.Here,we present a review of the main findings from the literature over the period 2011-18 with regard to the characteristics of O3 concentrations in China and the mechanisms that drive its interannual to decadal variations,aiming to identify robust conclusions that may guide decision-making for emissions control and to highlight critical knowledge gaps.We also review regional and global modeling studies that have investigated the impacts of tropospheric O3 on climate,as well as the projections of future tropospheric O3 owing to climate and/or emission changes.展开更多
Aluminum （AI） toxicity and phosphorous （P） deficiency are two major limiting factors for plant growth on acidic soils. Thus, the physiological mechanisms for AJ tolerance and P acquisition have been intensively st...Aluminum （AI） toxicity and phosphorous （P） deficiency are two major limiting factors for plant growth on acidic soils. Thus, the physiological mechanisms for AJ tolerance and P acquisition have been intensively studied. A commonly observed trait is that plants have developed the ability to utilize organic acid anions （OAs; mainly malate, citrate and oxalate） to combat AI toxicity and P deficiency. OAs secreted by roots into the rhizosphere can externally chelate Al^3＋ and mobilize phosphate （Pi）, while OAs synthesized in the cell can internally sequester Al^3＋ into the vacuole and release free Pi for metabolism. Molecular mechanisms involved in OA synthesis and transport have been described in detail. Ensuing genetic improvement for AI tolerance and P efficiency through increased OA exudation and/or synthesis in crops has been achieved by transgenic and marker-assisted breeding. This review mainly elucidates the crucial roles of OAs in plant Al tolerance and P efficiency through summarizing associated physiological mechanisms, molecular traits and genetic manipulation of crops.展开更多
Atmospheric chemistry research has been growing rapidly in China in the last 25 years since the concept of the“air pollution complex”was first proposed by Professor Xiaoyan TANG in 1997.For papers published in 2021 ...Atmospheric chemistry research has been growing rapidly in China in the last 25 years since the concept of the“air pollution complex”was first proposed by Professor Xiaoyan TANG in 1997.For papers published in 2021 on air pollution(only papers included in the Web of Science Core Collection database were considered),more than 24000 papers were authored or co-authored by scientists working in China.In this paper,we review a limited number of representative and significant studies on atmospheric chemistry in China in the last few years,including studies on(1)sources and emission inventories,(2)atmospheric chemical processes,(3)interactions of air pollution with meteorology,weather and climate,(4)interactions between the biosphere and atmosphere,and(5)data assimilation.The intention was not to provide a complete review of all progress made in the last few years,but rather to serve as a starting point for learning more about atmospheric chemistry research in China.The advances reviewed in this paper have enabled a theoretical framework for the air pollution complex to be established,provided robust scientific support to highly successful air pollution control policies in China,and created great opportunities in education,training,and career development for many graduate students and young scientists.This paper further highlights that developing and low-income countries that are heavily affected by air pollution can benefit from these research advances,whilst at the same time acknowledging that many challenges and opportunities still remain in atmospheric chemistry research in China,to hopefully be addressed over the next few decades.展开更多
Rice is one of the most important cereal crops in the world, and a substantial increase in grain yield is necessary for food security. However, high yields of semidwarf modern rice varieties are heavily dependent on t...Rice is one of the most important cereal crops in the world, and a substantial increase in grain yield is necessary for food security. However, high yields of semidwarf modern rice varieties are heavily dependent on the application of mineral nitrogenous fertilizer (Tilman et al., 2002;Sun et al., 2014). Nitrogen (N)-insensitive sponses associated with reduced N-use efficiency (NUE) is a major characteristic of the green revolution varieties (GRVs), in which the growth-inhibiting protein SLENDER RICE1 (SLR1) accumulates (Li et al., 2018). Unfortunately, increasing the level of N fertilizer use to reach the full yield potential of GRVs is subject to diminishing returns, quite apart from its deleterious effect on the environments (Rahn et al., 2009;Liu et al., 2015). Therefore, there is an urgent need to develop new rice GRVs that increase NUE while maintaining their high yields. Recently, several genes (e.g., DEP1, OsNRTl.lB, OsNRT2.3b, ARE1 and GRF4) responsible for improved NUE have been identified in rice (Sun et al.. 2014;Hu et al., 2015;Fan et al., 2016;Wang et al., 2018;Li et al., 2018). More importantly, boosting the activity of the transcription factor GRF4 overcomes the ability of SLR1 to prevent the GRF4-GIF1 interaction, which in turn promotes the coordinated expression of the genes involved in N assimilation and carbon fixation and consequently enhances the NUE of rice GRVs, thereby improving our ability to grow crops sustainably (Li et al., 2018). However, current understanding of the genetic basis for improving NUE remains at the level of identification of a number of quantitative trait loci (QTLs), without any understanding of the nature of the gene products.展开更多
China has implemented a series of emission reduction policies since 2013,and the concentration of air pollutants has consequently decreased significantly.However,PM_(2.5)(particulate matter with an aerodynamic diamete...China has implemented a series of emission reduction policies since 2013,and the concentration of air pollutants has consequently decreased significantly.However,PM_(2.5)(particulate matter with an aerodynamic diameter less than_(2.5)μm)pollution still occurs in China in relation to the interannual variations in meteorological conditions.Considering that El Nino-Southern Oscillation(ENSO)is the strongest signalmodulating the interannual variation in the atmosphere-ocean system,in this study the authors investigate the variations in PM_(2.5)concentrations in four megacity clusters of China during the winter season associated with four individual ENSO events from 2014 to 2021.Results show that the wintertime PM_(2.5) concentrations in the Beijing-Tianjin-Hebei and Fenwei Plain regions during El Nino years are higher than those during La Nina years,which can be explained by the anomalous southerly(northerly)winds during El Nino(La Nina) favoring PM_(2.5) accumulation(diffusion).In the Pearl River Delta region,PM_(2.5)concentrations decrease in El Nino relative to La Nina years owing to the enhanced water vapor flux and precipitation,removing more PM_(2.5)from the atmosphere.The comprehensive effects of wind and precipitation anomalies lead to the unpredictability of the impacts of ENSO on PM_(2.5)over the Yangtze River Delta region,which should be analyzed case by case.展开更多
Acid soils occupy approximately 50% of potentially arable lands.Improving crop productivity in acid soils,therefore,will be crucial for ensuring food security and agricultural sustainability.High soil acidity often co...Acid soils occupy approximately 50% of potentially arable lands.Improving crop productivity in acid soils,therefore,will be crucial for ensuring food security and agricultural sustainability.High soil acidity often coexists with phosphorus(P) deficiency and aluminum(Al) toxicity,a combination that severely impedes crop growth and yield across wide areas.As roots explore soil for the nutrients and water required for plant growth and development,they also sense and respond to below-ground stresses.Within the terrestrial context of widespread P deficiency and Al toxicity pressures,plants,particularly roots,have evolved a variety of mechanisms for adapting to these stresses.As legumes,soybean(Glycine max) plants may acquire nitrogen(N) through symbiotic nitrogen fixation(SNF),an adaptation that can be useful for mitigating excessive N fertilizer use,either directly as leguminous crop participants in rotation and intercropping systems,or secondarily as green manure cover crops.In this review,we investigate legumes,especially soybean,for recent advances in our understanding of root-based mechanisms linked with root architecture modification,exudation and symbiosis,together with associated genetic and molecular strategies in adaptation to individual and/or interacting P and Al conditions in acid soils.We propose that breeding legume cultivars with superior nutrient efficiency and/or Al tolerance traits through genetic selection might become a potentially powerful strategy for producing crop varieties capable of maintaining or improving yields in more stressful soil conditions subjected to increasingly challenging environmental conditions.展开更多
Complex air pollution problems have resulted in considerable adverse impacts on the environment,human health,and economy in China.However,owing to strict regulations since 2013,the air quality has been greatly improve...Complex air pollution problems have resulted in considerable adverse impacts on the environment,human health,and economy in China.However,owing to strict regulations since 2013,the air quality has been greatly improved.Now,the prevention of air pollution has entered a critical stage in combination with climate change mitigation in China.Accurate seasonal to interannual prediction of air pollution(haze,surface 03,and sandstorms) could support the government in planning for air pollution control on an annual basis.Scientists from all over the world have made great progress in understanding climate change and the variability of air pollution and associated physical mechanisms in China,which has provided a scientific basis for the development of climate prediction of air pollution.This paper reviews the progress made in air-pollution climate prediction,and gives some critical insights including update of predictand,change of predictability,and development of coupled model.展开更多
Frequent occurrences of extreme heat are causing severe ozone pollution over China.This study examined the driving factors of urban ozone pollution in China during the extremely hot summer of 2022 and the impact of em...Frequent occurrences of extreme heat are causing severe ozone pollution over China.This study examined the driving factors of urban ozone pollution in China during the extremely hot summer of 2022 and the impact of emission control strategies using surface measurements and the GEOS-Chem model.The results show that ozone pollution was extremely severe in summer 2022,with a significant rebound by 12-15 ppbv in the North China Plain(NCP),Yangtze River Delta(YRD),and Sichuan basin(SCB),compared to 2021.Especially over the NCP,the MDA8(maximum daily 8-hourly average)ozone exceeded 160 ppbv,and the number of ozone exceedances was over 42 days.Based on an IPR(integrated process rate)analysis,the authors found that the net chemical production was the dominant factor contributing to the strong ozone increase in summer 2022.For example,in June over the NCP,the net chemical production resulted in an increase by 3.08 Gg d^(−1)(∼270%)in ozone mass change.Sensitivity simulations showed that both NO_(x)(nitrogen oxides)and VOC(volatile organic compound)reductions were important over the NCP,and NO_(x)reductions were more important than VOCs over southern China.To keep the ozone of 2022 at the same level as 2021,a joint reduction of NO_(x)and VOCs by at least 50%-60%would have been required.This study highlights the urgency to develop effective ozone management since extreme heat will become more frequent.展开更多
A Gram-negative, aerobic, non-motile, rod-shaped bacterial strain, designated 25-1T, was isolated from the air inside giant panda enclosures at the Chengdu Research Base of Giant Panda Breeding, China. Strain 25-1T gr...A Gram-negative, aerobic, non-motile, rod-shaped bacterial strain, designated 25-1T, was isolated from the air inside giant panda enclosures at the Chengdu Research Base of Giant Panda Breeding, China. Strain 25-1T grew optimally at pH 7.0-8.0, at 28-30 ℃ and in the presence of NaCI concentrations from 0.0% to 0.5%. 16S rRNA gene sequence analysis indicated that strain 25-1m belongs to the genus Chryseobacterium within the family Flavo- bacteriaceae and is related most closely to C. camis G81m （96.4% similarity）, C. lathyri RBA2-6T （95.8% similarity）, and C. zeae JM1085T （95.8% similarity）. Its genomic DNA G＋C molar composition was 36.2%. The major cellular fatty acids were iso-C15：0 （44.0%）, iso-C17：0 3OH （19.8%） and C16：1 ω7c/16：1 ω6c （12.7%）. The only isoprenoid quinone was menaquinone 6 （MK-6）. The major polar lipids were phosphatidylethanolamine, two unidentified amino lipids and two unidentified lipids. The DNA-DNA relatedness between strain 25-1m and C. lathyri RBA2-6T was 38%. Phenotypic, genotypic, and phylogenetic characteristics indicated that strain 25-1T is a novel member of the genus Chryseobacterium, for which the name C. chengduensis sp. nov. is proposed. The type strain is 25-1T （ccmoc AB2015133T=DSM 100396T）.展开更多
基金supported by the National Natural Science Foundation of China(Nos.42007325 and 42177211).
文摘To understand the differences in the composition and sources of PM_(2.5) and PM_(10) caused by coarse particles,integrated PM_(2.5) and PM_(10) samples were synchronously collected in Nanjing,East China,in summer 2020 and winter 2020/2021.Bulk and molecular speciation and light absorption measurements of aerosol extractswere performed,followed by positivematrix factorization(PMF)based on the PM_(2.5) and PM_(10) data sets,respectively.The difference in average concentrations of total bulk species between PM_(2.5) and PM_(10) was mainly caused by the distribution of considerable NO_(3)^(–),SO42–,Ca^(2+),and organic carbon(OC)in coarse particles.Coarse PMinfluenced by abrasion products from tirewear and leaves contributed about half of the low-volatility n-alkanes in summer.The contribution of coarse PM to biomass burning tracers and water-soluble OC increased in winter when biomass combustion was excessively active.More than 70%of sugar polyols were attributable to coarse PM in summer,and biomass burning could be an important source in winter.The light-absorbing organic chromophores were almost entirely associated with PM_(2.5),but water-soluble organic carbon(WSOC)exhibited stronger light absorption in PM_(10) extracts than in PM_(2.5) extracts possibly due to the influence of coarse PMon pH.PMF analysis indicated that biomass burning,aqueous-phase reactions,and processed dust were the main contributors of organic matter and its light absorption in winter.Biogenic primary and secondary sources made discernable contributions only in summer.The differences between PM_(2.5) and PM_(10) were likely attributed to mixing of crustal dust,combustion particles,and surface reactions.
基金supported by the National Key Research and Development Program of China(No.2021YFA0910500)the National Natural Science Foundation of China(Nos.U22A20380,82173706,and 82104028)the Science and Technology Major Project of Hubei Province(No.2021ACA012).
文摘(±)-Talapyrones A−F(1−6),six pairs of dimeric polyketide enantiomers featuring unusual 6/6/6 and 6/6/6/5 ring systems,were isolated from the fungus Talaromyces adpressus.Their structures were determined by spectroscopic analysis and HR-ESI-MS data,and their absolute configurations were elucidated using a modified Mosher’s method and electronic circular dichroism(ECD)calculations.(±)-Talapyrones A−F(1−6)possess a 6/6/6 tricyclic skeleton,presumably formed through a Michael addition reaction between one molecule ofα-pyrone derivative and one molecule of C8 poly-β-keto chain.In addition,compounds 2/3 and 4/5 are two pairs of C-18 epimers,respectively.Putative biosynthetic pathways of 1−6 were discussed.
基金supported by the Natural Science Foundation of Jiangsu Province[grant number BK20220031]the National Natural Science Foundation of China[grant number 42007195].
文摘Renewable energy,especially solar power,is vital for mitigating global warming,while climate change also impacts solar photovoltaic potential(PVpot).This study analyzes historical(1985–2014)and future(2015–2100)climate effects on PVpot,and quantifies contributions from changed radiation,temperature,and wind speed.Historically,global PVpot increased by 0.42‰,with notable rises in eastern China(+7.1‰)and southern Europe(+3.5‰).By the end of the century,increased radiation-induced PVpot(+1.27‰)offsets temperatureinduced PVpot loss(−0.54‰)under SSP1-2.6,yielding a net PVpot increase(+0.74‰).Under SSP2-4.5,the temperature-induced PVpot decline(−1.50‰)drives the final PVpot reduction(−1.15‰).Under SSP3-7.0 and SSP5-8.5,combined radiation-induced(−1.94‰and−1.99‰)and temperature-induced PVpot changes(−2.67‰and−3.41‰)result in significant PVpot declines(−4.57‰and−5.31‰).Regional analysis reveals that eastern China(+0.7‰to+8.6‰),southern Europe(+0.3‰to+2.5‰),and Northwest South America(+0.6‰to+2.1‰)retain positive changes in future PVpot across all climate scenarios,which may be due to reduced aerosols and cloud cover,suggesting these areas can remain suitable for photovoltaic installations despite climate changes.In contrast,temperature-driven PVpot declines over the Qinghai-Tibet Plateau(−9.1‰to−4.3‰)and northern Africa(−9.3‰to−4.9‰)under future high-emission scenarios indicate that these historically advantageous regions will become less suitable for solar energy deployment.The findings underscore that climate changes driven by sustainable development pathways will generate more PVpot in the future for better global warming mitigation.
基金supported by the National Natural Science Foundation of China(Grant No.91744311).
文摘We used observed concentrations of air pollutants,reanalyzed meteorological parameters,and results from the Goddard Earth Observing System Chemical Transport Model to examine the relationships between concentrations of maximum daily 8-h average ozone(MDA8 O_(3)),PM_(2.5)(particulate matter with diameter of 2.5μm or less),and PM_(2.5)components and 2-m temperature(T2)or relative humidity(RH),as well as the effectiveness of precursor emission reductions on the control of O_(3) and PM_(2.5) in Beijing–Tianjin–Hebei(BTH)under different summertime temperature and humidity conditions.Both observed(simulated)MDA8 O_(3) and PM_(2.5) concentrations increased as T2 went up,with linear trends of 4.8(3.2)ppb℃^(−1) and 1.9(1.5)μg m^(−3)℃^(−1),respectively.Model results showed that the decreases in MDA8 O_(3) from precursor emission reductions were more sensitive to T2 than to RH.Reducing a larger proportion of volatile organic compound(VOC)emissions at higher T2 was more effective for the control of summertime O_(3) in BTH.For the control of summertime PM_(2.5) in BTH,reducing nitrogen oxides(NOx)combined with a small proportion of VOCs was the best measure.The magnitude of reduction in PM_(2.5) from reducing precursor emissions was more sensitive to RH than to T2,with the best efficiency at high RH.Results from this study are helpful for formulating effective policies to tackle O_(3) and PM_(2.5) pollution in BTH.
基金supported by Grants of the National Natural Science Foundation of China(82073831)Natural Science Foundation of Chongqing(CSTB2023NSCQ-MSX0656)China Postdoctoral Science Foundation(2023M733889).
文摘Glutamate is an essential excitatory neurotransmitter in the brain,playing a vital role in regulating synaptic activity and maintaining the homeostasis of the cerebral environment but also serves as a central hub for neuronal injury and inflammatory responses.In various pathological conditions,such as ischemic stroke,glutamate is released and accumulates excessively in the brain,leading to heightened stimulation of neurons and excitotoxicity.This phenomenon positions glutamate as a primary inducing factor for neuronal damage following cerebral ischemia.Glutamate exerts its effects primarily through two types of receptors:ionotropic andmetabotropic glutamate receptors,both of which are extensively distributed throughout the hippocampus and cortical regions of the brain.Ionotropic receptors mediate rapid excitatory neurotransmission upon activation by glutamate;these are mainly categorized into N-methyl-D-aspartate receptors(NMDARs),α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptors(AMPARs),and kainate receptors(KARs).Conversely,metabotropic receptors function asG-protein-coupled receptors(GPCR)facilitating glutamatergic cellular effects via intracellular secondmessenger.With the comprehensive investigation of glutamate receptors and their structural characteristics,our understanding of the nerve damage and protective mechanisms associated with glutamate receptors in ischemic stroke is progressively advancing.Consequently,exploring the role of glutamate receptors and their downstream signaling pathways in cerebral ischemia can provide a robust theoretical foundation for targeted therapies aimed at treating cerebral ischemia,stroke,and related disorders.This article reviews the function of glutamate receptors and theirmediated downstreamsignal transduction pathways in the context of ischemic brain injury.
基金the National Natural Science Foundation of China(Grant No.91844000)is acknowledged.
文摘1.Background Air pollution is a global environmental problem and has serious impacts on human health,climate change,and ecological systems.From the lessons learned by developed countries,the use of various energy types can result in different types of air pollution,such as smoke from coal burning and photochemical smog from gasoline/diesel vehicle emissions.Meanwhile,in China,rapid development in the last several decades has led to a drastic increase in coal consumption and the number of vehicles;and consequently,air pollution in China is complicated by the coexistence of high concentrations of primary and secondary trace gases and aerosol particles from multiple sources.The concept of an“air pollution complex”was first proposed by Xiaoyan TANG in 1997 to characterize the complexity of the formation mechanisms of air pollution,and calls for science-based control strategies(Zhu,2005).
基金supported by the National Natural Science Foundation of China(Grant Nos.91744311 and91544219)the National Key Research and Development Program of China(Grant No.2016YFA0600203)the National Natural Science Foundation of China(Grant No.41405138)
文摘China has been experiencing widespread air pollution due to rapid industrialization and urbanization in recent decades.The two major concerns of ambient air quality in China are particulate matter(PM)and tropospheric ozone(O3).With the implementation of air pollution prevention and control actions in the last five years,the PM pollution in China has been substantially reduced.In contrast,under the conditions of the urban air pollution complex,the elevated O3 levels in city clusters of eastern China,especially in warm seasons,have drawn increasing attention.Emissions of air pollutants and their precursors not only contribute to regional air quality,but also alter climate.Climate change in turn can change chemical processes,long-range transport,and local meteorology that influence air pollution.Compared to PM,less is known about O3 pollution and its climate effects over China.Here,we present a review of the main findings from the literature over the period 2011-18 with regard to the characteristics of O3 concentrations in China and the mechanisms that drive its interannual to decadal variations,aiming to identify robust conclusions that may guide decision-making for emissions control and to highlight critical knowledge gaps.We also review regional and global modeling studies that have investigated the impacts of tropospheric O3 on climate,as well as the projections of future tropospheric O3 owing to climate and/or emission changes.
基金financially supported by the National Natural Science Foundation of China(No.U1301212)the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB15030202)
文摘Aluminum （AI） toxicity and phosphorous （P） deficiency are two major limiting factors for plant growth on acidic soils. Thus, the physiological mechanisms for AJ tolerance and P acquisition have been intensively studied. A commonly observed trait is that plants have developed the ability to utilize organic acid anions （OAs; mainly malate, citrate and oxalate） to combat AI toxicity and P deficiency. OAs secreted by roots into the rhizosphere can externally chelate Al^3＋ and mobilize phosphate （Pi）, while OAs synthesized in the cell can internally sequester Al^3＋ into the vacuole and release free Pi for metabolism. Molecular mechanisms involved in OA synthesis and transport have been described in detail. Ensuing genetic improvement for AI tolerance and P efficiency through increased OA exudation and/or synthesis in crops has been achieved by transgenic and marker-assisted breeding. This review mainly elucidates the crucial roles of OAs in plant Al tolerance and P efficiency through summarizing associated physiological mechanisms, molecular traits and genetic manipulation of crops.
基金funded by the National Natural Science Foundation of China(Grant No.91844000)。
文摘Atmospheric chemistry research has been growing rapidly in China in the last 25 years since the concept of the“air pollution complex”was first proposed by Professor Xiaoyan TANG in 1997.For papers published in 2021 on air pollution(only papers included in the Web of Science Core Collection database were considered),more than 24000 papers were authored or co-authored by scientists working in China.In this paper,we review a limited number of representative and significant studies on atmospheric chemistry in China in the last few years,including studies on(1)sources and emission inventories,(2)atmospheric chemical processes,(3)interactions of air pollution with meteorology,weather and climate,(4)interactions between the biosphere and atmosphere,and(5)data assimilation.The intention was not to provide a complete review of all progress made in the last few years,but rather to serve as a starting point for learning more about atmospheric chemistry research in China.The advances reviewed in this paper have enabled a theoretical framework for the air pollution complex to be established,provided robust scientific support to highly successful air pollution control policies in China,and created great opportunities in education,training,and career development for many graduate students and young scientists.This paper further highlights that developing and low-income countries that are heavily affected by air pollution can benefit from these research advances,whilst at the same time acknowledging that many challenges and opportunities still remain in atmospheric chemistry research in China,to hopefully be addressed over the next few decades.
基金supported by grants from the National Natural Science Foundation of China (31830082)the National Key Research and Development Program of China (2016YFD0100401)the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB27010000)
文摘Rice is one of the most important cereal crops in the world, and a substantial increase in grain yield is necessary for food security. However, high yields of semidwarf modern rice varieties are heavily dependent on the application of mineral nitrogenous fertilizer (Tilman et al., 2002;Sun et al., 2014). Nitrogen (N)-insensitive sponses associated with reduced N-use efficiency (NUE) is a major characteristic of the green revolution varieties (GRVs), in which the growth-inhibiting protein SLENDER RICE1 (SLR1) accumulates (Li et al., 2018). Unfortunately, increasing the level of N fertilizer use to reach the full yield potential of GRVs is subject to diminishing returns, quite apart from its deleterious effect on the environments (Rahn et al., 2009;Liu et al., 2015). Therefore, there is an urgent need to develop new rice GRVs that increase NUE while maintaining their high yields. Recently, several genes (e.g., DEP1, OsNRTl.lB, OsNRT2.3b, ARE1 and GRF4) responsible for improved NUE have been identified in rice (Sun et al.. 2014;Hu et al., 2015;Fan et al., 2016;Wang et al., 2018;Li et al., 2018). More importantly, boosting the activity of the transcription factor GRF4 overcomes the ability of SLR1 to prevent the GRF4-GIF1 interaction, which in turn promotes the coordinated expression of the genes involved in N assimilation and carbon fixation and consequently enhances the NUE of rice GRVs, thereby improving our ability to grow crops sustainably (Li et al., 2018). However, current understanding of the genetic basis for improving NUE remains at the level of identification of a number of quantitative trait loci (QTLs), without any understanding of the nature of the gene products.
基金This study was supported by the National Natural Science Foundation of China[grant number 41975159]the National Key Research and Development Program of China[grant numbers 2020YFA0607803 and 2019YFA0606800].
文摘China has implemented a series of emission reduction policies since 2013,and the concentration of air pollutants has consequently decreased significantly.However,PM_(2.5)(particulate matter with an aerodynamic diameter less than_(2.5)μm)pollution still occurs in China in relation to the interannual variations in meteorological conditions.Considering that El Nino-Southern Oscillation(ENSO)is the strongest signalmodulating the interannual variation in the atmosphere-ocean system,in this study the authors investigate the variations in PM_(2.5)concentrations in four megacity clusters of China during the winter season associated with four individual ENSO events from 2014 to 2021.Results show that the wintertime PM_(2.5) concentrations in the Beijing-Tianjin-Hebei and Fenwei Plain regions during El Nino years are higher than those during La Nina years,which can be explained by the anomalous southerly(northerly)winds during El Nino(La Nina) favoring PM_(2.5) accumulation(diffusion).In the Pearl River Delta region,PM_(2.5)concentrations decrease in El Nino relative to La Nina years owing to the enhanced water vapor flux and precipitation,removing more PM_(2.5)from the atmosphere.The comprehensive effects of wind and precipitation anomalies lead to the unpredictability of the impacts of ENSO on PM_(2.5)over the Yangtze River Delta region,which should be analyzed case by case.
基金financially supported by the National Natural Science Foundation of China (32072661)the National Key Research and Development Program of China(2021YFF1000500)。
文摘Acid soils occupy approximately 50% of potentially arable lands.Improving crop productivity in acid soils,therefore,will be crucial for ensuring food security and agricultural sustainability.High soil acidity often coexists with phosphorus(P) deficiency and aluminum(Al) toxicity,a combination that severely impedes crop growth and yield across wide areas.As roots explore soil for the nutrients and water required for plant growth and development,they also sense and respond to below-ground stresses.Within the terrestrial context of widespread P deficiency and Al toxicity pressures,plants,particularly roots,have evolved a variety of mechanisms for adapting to these stresses.As legumes,soybean(Glycine max) plants may acquire nitrogen(N) through symbiotic nitrogen fixation(SNF),an adaptation that can be useful for mitigating excessive N fertilizer use,either directly as leguminous crop participants in rotation and intercropping systems,or secondarily as green manure cover crops.In this review,we investigate legumes,especially soybean,for recent advances in our understanding of root-based mechanisms linked with root architecture modification,exudation and symbiosis,together with associated genetic and molecular strategies in adaptation to individual and/or interacting P and Al conditions in acid soils.We propose that breeding legume cultivars with superior nutrient efficiency and/or Al tolerance traits through genetic selection might become a potentially powerful strategy for producing crop varieties capable of maintaining or improving yields in more stressful soil conditions subjected to increasingly challenging environmental conditions.
基金supported by the National Natural Science Foundation of China [grant numbers 4208810191744311+1 种基金42025502and 41991283]。
文摘Complex air pollution problems have resulted in considerable adverse impacts on the environment,human health,and economy in China.However,owing to strict regulations since 2013,the air quality has been greatly improved.Now,the prevention of air pollution has entered a critical stage in combination with climate change mitigation in China.Accurate seasonal to interannual prediction of air pollution(haze,surface 03,and sandstorms) could support the government in planning for air pollution control on an annual basis.Scientists from all over the world have made great progress in understanding climate change and the variability of air pollution and associated physical mechanisms in China,which has provided a scientific basis for the development of climate prediction of air pollution.This paper reviews the progress made in air-pollution climate prediction,and gives some critical insights including update of predictand,change of predictability,and development of coupled model.
基金supported by the National Key Research and Development Program of China[grant number 2022YFE0136100]the National Natural Science Foundation of China[grant number 42205114].
文摘Frequent occurrences of extreme heat are causing severe ozone pollution over China.This study examined the driving factors of urban ozone pollution in China during the extremely hot summer of 2022 and the impact of emission control strategies using surface measurements and the GEOS-Chem model.The results show that ozone pollution was extremely severe in summer 2022,with a significant rebound by 12-15 ppbv in the North China Plain(NCP),Yangtze River Delta(YRD),and Sichuan basin(SCB),compared to 2021.Especially over the NCP,the MDA8(maximum daily 8-hourly average)ozone exceeded 160 ppbv,and the number of ozone exceedances was over 42 days.Based on an IPR(integrated process rate)analysis,the authors found that the net chemical production was the dominant factor contributing to the strong ozone increase in summer 2022.For example,in June over the NCP,the net chemical production resulted in an increase by 3.08 Gg d^(−1)(∼270%)in ozone mass change.Sensitivity simulations showed that both NO_(x)(nitrogen oxides)and VOC(volatile organic compound)reductions were important over the NCP,and NO_(x)reductions were more important than VOCs over southern China.To keep the ozone of 2022 at the same level as 2021,a joint reduction of NO_(x)and VOCs by at least 50%-60%would have been required.This study highlights the urgency to develop effective ozone management since extreme heat will become more frequent.
基金supported by the Chengdu Giant Panda Breeding Research Foundation(No.CPF2010-06)the National Key Technology R&D Program of China(No.2012BAC01B06)
文摘A Gram-negative, aerobic, non-motile, rod-shaped bacterial strain, designated 25-1T, was isolated from the air inside giant panda enclosures at the Chengdu Research Base of Giant Panda Breeding, China. Strain 25-1T grew optimally at pH 7.0-8.0, at 28-30 ℃ and in the presence of NaCI concentrations from 0.0% to 0.5%. 16S rRNA gene sequence analysis indicated that strain 25-1m belongs to the genus Chryseobacterium within the family Flavo- bacteriaceae and is related most closely to C. camis G81m （96.4% similarity）, C. lathyri RBA2-6T （95.8% similarity）, and C. zeae JM1085T （95.8% similarity）. Its genomic DNA G＋C molar composition was 36.2%. The major cellular fatty acids were iso-C15：0 （44.0%）, iso-C17：0 3OH （19.8%） and C16：1 ω7c/16：1 ω6c （12.7%）. The only isoprenoid quinone was menaquinone 6 （MK-6）. The major polar lipids were phosphatidylethanolamine, two unidentified amino lipids and two unidentified lipids. The DNA-DNA relatedness between strain 25-1m and C. lathyri RBA2-6T was 38%. Phenotypic, genotypic, and phylogenetic characteristics indicated that strain 25-1T is a novel member of the genus Chryseobacterium, for which the name C. chengduensis sp. nov. is proposed. The type strain is 25-1T （ccmoc AB2015133T=DSM 100396T）.
