The Paleogene geological framework and evolution process in the central anticline zone in the Lufeng 13 sag in Pearl River Mouth Basin is well analyzed through seismic data and drilling data,and control of tectonic ev...The Paleogene geological framework and evolution process in the central anticline zone in the Lufeng 13 sag in Pearl River Mouth Basin is well analyzed through seismic data and drilling data,and control of tectonic evolution on hydrocarbon accumulation is also discussed.The results show that the central anticline zone in the Lufeng 13 sag develops the upper deformation layer and lower deformation layer.The“arched graben system”is developed in the upper deformation layer,and the magmatic diapir structure and flowing deformation of plastic strata is developed in the lower deformation layer.The evolution process of the central anticline zone can be divided into four stages,i.e.fault block uplifting stage,prototype stage,strengthening stage and finalization stage.The geological framework and tectonic evolution of the central anticline zone control Paleogene hydrocarbon accumulation.The Paleogene twolayer geological framework is favorable for development of structural traps and composite traps;the paleostructure highs are the direction of hydrocarbon migration,and the gravitational gliding faults are the main carrier bed for vertical hydrocarbon migration;the tectonic uplift is a key factor for reservoir diagenesis improvement and preservation of primary pores,and also controls distribution of high-quality reservoirs.展开更多
Folliculogenesis is essential for production of female gametes in vertebrates.However,the molecular mechanisms underlying follicle development,particularly apoptosis regulation in ovary,remain elusive.Here,we gen erat...Folliculogenesis is essential for production of female gametes in vertebrates.However,the molecular mechanisms underlying follicle development,particularly apoptosis regulation in ovary,remain elusive.Here,we gen erated sox3 knockout zebrafish lines using CRISPR/Cas9.sox3 knockout led to follicle development retardation and a reduced fecundity in females.Comparative analysis of transcriptome between sox3^-/-and wild-type ovaries revealed that Sox3 was invoIved in pathways of ovarian steroidogenesis and apoptosis.Knockout of sox3 promoted follicle apoptosis and obvious apoptosis signals were detected in somatic cells of stages III and IV follicles of sox3^-/-ovaries.Moreover,Sox3 can bind to and activate the promoter of cyp19a1a.Up-regulation of Cyp19a1a expression promoted 17β-estradiol synthesis,which inhibited apoptosis in follicle development.Thus,Sox3 functions as a regulator of Cyp19a1a expression,via 17β-E2 linking apoptosis suppression,which is implicated in improving female fecundity.展开更多
A novel phenolic rigid organic filler(KT)was melt-mixed with an isotactic polypropylene(iPP)to prepare a series of PP/KT composites,with or without maleic anhydride grafted polypropylene(MAPP)as compatilizer.The evolu...A novel phenolic rigid organic filler(KT)was melt-mixed with an isotactic polypropylene(iPP)to prepare a series of PP/KT composites,with or without maleic anhydride grafted polypropylene(MAPP)as compatilizer.The evolution of filler morphology during melt-mixing and melt-pressure processes was monitored by scanning electron microscope(SEM)and polarized optical microscope(POM).The influences of shear force,pressure time,filler content and MAPP concentration on the final filler dispersion were studied.We found that this rigid organic filler readily melted and dispersed homogenously into the iPP matrix through a fission-fusion process during the melt-mixing process.Thus a balanced dispersion,which was closely related to shear force and MAPP concentration,can be achieved.During the meltpressure process,parts of the filler particles combined gradually through a coalescence process.However,the incorporation of MAPP can effectively inhibit the tendency to coalesce and refine the filler particles sizes into nanoscale.Thus,a series of PP/KT composites with controllable filler particles size and narrow size distribution can be obtained just by adjusting process conditions and MAPP concentration.In addition,due to the in-situ formation mechanism,the filler phase possessed a typical solid true-spherical shape.展开更多
A novel phenolic rigid organic filler(KT)was used to modify isotactic polypropylene(iPP).The influence of KT particles on the impact resistance property of PP/KT specimens(with similar interparticles distance,1.8μm)w...A novel phenolic rigid organic filler(KT)was used to modify isotactic polypropylene(iPP).The influence of KT particles on the impact resistance property of PP/KT specimens(with similar interparticles distance,1.8μm)was studied by notched izod impact tests.It was found that the brittle-ductile transition(BDT)of the PP/KT microcomposites took place at the filler content of about 4%,and the impact strength attains the maximum at 5%(with filler particles size of 1.5μm),which is about 2.5 times that of unfilled iPP specimens.The impact fracture morphology was investigated by scanning electron micro-scopy(SEM).For the PP/KT specimens and the high-density polyethylene/KT(HDPE/KT)specimens in ductile fracture mode,many microfibers could be found on the whole impact fracture surface.It was the filler particles that induced the plastic deformation of interparticles ligament and hence improved the capability of iPP matrix on absorbing impact energy dramatically.The determinants on the BDT were further discussed on the basis of stress concentration and debonding resistance.It can be con-cluded that aside from the interparticle distance,the filler particles size also plays an important role in semicrystal-line polymer toughening.展开更多
基金supported by the National Science and Technology Major Project of China(No.2016ZX05024-004)comprehensive scientific research project of CNOOC(China National Offshore Oil Corporation)(YXKY-2015-SZ-02).
文摘The Paleogene geological framework and evolution process in the central anticline zone in the Lufeng 13 sag in Pearl River Mouth Basin is well analyzed through seismic data and drilling data,and control of tectonic evolution on hydrocarbon accumulation is also discussed.The results show that the central anticline zone in the Lufeng 13 sag develops the upper deformation layer and lower deformation layer.The“arched graben system”is developed in the upper deformation layer,and the magmatic diapir structure and flowing deformation of plastic strata is developed in the lower deformation layer.The evolution process of the central anticline zone can be divided into four stages,i.e.fault block uplifting stage,prototype stage,strengthening stage and finalization stage.The geological framework and tectonic evolution of the central anticline zone control Paleogene hydrocarbon accumulation.The Paleogene twolayer geological framework is favorable for development of structural traps and composite traps;the paleostructure highs are the direction of hydrocarbon migration,and the gravitational gliding faults are the main carrier bed for vertical hydrocarbon migration;the tectonic uplift is a key factor for reservoir diagenesis improvement and preservation of primary pores,and also controls distribution of high-quality reservoirs.
基金the National Natural Science Foundation of China and National Key Technologies R&D Program.
文摘Folliculogenesis is essential for production of female gametes in vertebrates.However,the molecular mechanisms underlying follicle development,particularly apoptosis regulation in ovary,remain elusive.Here,we gen erated sox3 knockout zebrafish lines using CRISPR/Cas9.sox3 knockout led to follicle development retardation and a reduced fecundity in females.Comparative analysis of transcriptome between sox3^-/-and wild-type ovaries revealed that Sox3 was invoIved in pathways of ovarian steroidogenesis and apoptosis.Knockout of sox3 promoted follicle apoptosis and obvious apoptosis signals were detected in somatic cells of stages III and IV follicles of sox3^-/-ovaries.Moreover,Sox3 can bind to and activate the promoter of cyp19a1a.Up-regulation of Cyp19a1a expression promoted 17β-estradiol synthesis,which inhibited apoptosis in follicle development.Thus,Sox3 functions as a regulator of Cyp19a1a expression,via 17β-E2 linking apoptosis suppression,which is implicated in improving female fecundity.
基金supported by Japan Science and Technology Agency(JST)and Science Foundation of Zhejiang Sci-Tech University(ZSTU)(Grant No.0701064-Y).
文摘A novel phenolic rigid organic filler(KT)was melt-mixed with an isotactic polypropylene(iPP)to prepare a series of PP/KT composites,with or without maleic anhydride grafted polypropylene(MAPP)as compatilizer.The evolution of filler morphology during melt-mixing and melt-pressure processes was monitored by scanning electron microscope(SEM)and polarized optical microscope(POM).The influences of shear force,pressure time,filler content and MAPP concentration on the final filler dispersion were studied.We found that this rigid organic filler readily melted and dispersed homogenously into the iPP matrix through a fission-fusion process during the melt-mixing process.Thus a balanced dispersion,which was closely related to shear force and MAPP concentration,can be achieved.During the meltpressure process,parts of the filler particles combined gradually through a coalescence process.However,the incorporation of MAPP can effectively inhibit the tendency to coalesce and refine the filler particles sizes into nanoscale.Thus,a series of PP/KT composites with controllable filler particles size and narrow size distribution can be obtained just by adjusting process conditions and MAPP concentration.In addition,due to the in-situ formation mechanism,the filler phase possessed a typical solid true-spherical shape.
基金This work was supported by Japan Science and Technology Agency(JST)the National Natural Science Foundation of China(Grant No.50803058)Program for Changjiang Scholars and Innovative Research Team in University(No.0654).
文摘A novel phenolic rigid organic filler(KT)was used to modify isotactic polypropylene(iPP).The influence of KT particles on the impact resistance property of PP/KT specimens(with similar interparticles distance,1.8μm)was studied by notched izod impact tests.It was found that the brittle-ductile transition(BDT)of the PP/KT microcomposites took place at the filler content of about 4%,and the impact strength attains the maximum at 5%(with filler particles size of 1.5μm),which is about 2.5 times that of unfilled iPP specimens.The impact fracture morphology was investigated by scanning electron micro-scopy(SEM).For the PP/KT specimens and the high-density polyethylene/KT(HDPE/KT)specimens in ductile fracture mode,many microfibers could be found on the whole impact fracture surface.It was the filler particles that induced the plastic deformation of interparticles ligament and hence improved the capability of iPP matrix on absorbing impact energy dramatically.The determinants on the BDT were further discussed on the basis of stress concentration and debonding resistance.It can be con-cluded that aside from the interparticle distance,the filler particles size also plays an important role in semicrystal-line polymer toughening.
