A recent publication by Zhou et al.[1]in Neuron demonstrates that a specific interaction between astrocytes and a subtype of neurons has an influence on complex animal behavior,namely risk assessment.The majority of n...A recent publication by Zhou et al.[1]in Neuron demonstrates that a specific interaction between astrocytes and a subtype of neurons has an influence on complex animal behavior,namely risk assessment.The majority of neuroscientists analyzing the molecular and cellular substrate of behavior focus on neuronal circuits.Glial cells were originally described by Rudolf Virchow and the name glia refers to the Greek word for glue or putty.Thus,glial cells were long thought to represent simply the filling stuff of the brain.This view has changed dramatically in the last decades.The three major types of glial cells of the central nervous system fulfll diverse functions.Oligodendrocytes are the myelinforming cells and it has become evident that they are plastic and are able to influence neuronal connectivity.Microglia are the immune cells of the brain and interact with synapses during development,in plasticity,and very prominently in any disease of the nervous system.展开更多
The first issue of GLIA appeared 20 years ago.The journal will celebrate this land-mark quietly,but nonetheless it is with a great deal of pride and a certain amount of amazement that we look back over these two event...The first issue of GLIA appeared 20 years ago.The journal will celebrate this land-mark quietly,but nonetheless it is with a great deal of pride and a certain amount of amazement that we look back over these two eventful decades.This epoch encapsulates the blossoming of glial research into a mainstream area of neuroscience.In fact,it would be virtually impossible for someone not scientifically active in the mid-80s to appreciate how limited our understanding of these cells was at the time.The early years of GLIA,however,provide a suitable time capsule for that period and serve as a useful reminder of how some of today's "big ideas" developed.That GLIA played a role,however modest,in advancing what is now one of the most exciting fields of brain research seems worth noting.展开更多
基金supported by the Shenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases(ZDSYS20220304163558001).
文摘A recent publication by Zhou et al.[1]in Neuron demonstrates that a specific interaction between astrocytes and a subtype of neurons has an influence on complex animal behavior,namely risk assessment.The majority of neuroscientists analyzing the molecular and cellular substrate of behavior focus on neuronal circuits.Glial cells were originally described by Rudolf Virchow and the name glia refers to the Greek word for glue or putty.Thus,glial cells were long thought to represent simply the filling stuff of the brain.This view has changed dramatically in the last decades.The three major types of glial cells of the central nervous system fulfll diverse functions.Oligodendrocytes are the myelinforming cells and it has become evident that they are plastic and are able to influence neuronal connectivity.Microglia are the immune cells of the brain and interact with synapses during development,in plasticity,and very prominently in any disease of the nervous system.
文摘The first issue of GLIA appeared 20 years ago.The journal will celebrate this land-mark quietly,but nonetheless it is with a great deal of pride and a certain amount of amazement that we look back over these two eventful decades.This epoch encapsulates the blossoming of glial research into a mainstream area of neuroscience.In fact,it would be virtually impossible for someone not scientifically active in the mid-80s to appreciate how limited our understanding of these cells was at the time.The early years of GLIA,however,provide a suitable time capsule for that period and serve as a useful reminder of how some of today's "big ideas" developed.That GLIA played a role,however modest,in advancing what is now one of the most exciting fields of brain research seems worth noting.
