The linguistic landscape of traditional historic tourist attractions has undergone heterogeneous changes under the impact of globalization and tourism development.Guided by the linguistic landscape construction princi...The linguistic landscape of traditional historic tourist attractions has undergone heterogeneous changes under the impact of globalization and tourism development.Guided by the linguistic landscape construction principle and meaning combination analysis,taking the linguistic landscape of South Luogu Al ey in Beijing as the research object,its unique presentation and formation mechanism are analyzed and explicated in this paper.In the first part,we describe the elements of tradition and modernity presented in both private and official linguistic landscape.In the second part,we explain these characteristics,and the results show that:traditional elements dominated with each presents unique characteristics while modern elements especially English have been extensively employed than ever before,functioning as the information disseminator and prestige symbol.Finally,certain degrees of problems need to be meticulously considered so as to foster the renewal progress of the historic tourist attractions.展开更多
Red fruit peel is one of pear's most valuable economic traits and is mainly determined by anthocyanins.Many pear cultivars with a red peel originated from bud sports;however,little is known about the genetic mecha...Red fruit peel is one of pear's most valuable economic traits and is mainly determined by anthocyanins.Many pear cultivars with a red peel originated from bud sports;however,little is known about the genetic mechanisms underlying this trait.We have previously identified a mutant Pp BBX24 containing a 14-nucleotide deletion in the coding region(Ppbbx24-del)as the only known variant associated with the red coloration of the mutant‘Red Zaosu'pear(Pyrus pyrifolia White Pear Group).Herein,we analyzed the role of the mutant gene in red coloration and its mechanism of action.The results showed that light promoted red peel coloration in the‘Red Zaosu'pear,and Ppbbx24-del positively affected light-induced anthocyanin biosynthesis,while normal Pp BBX24 had the opposite effects.Transient and stable transformation experiments confirmed that Ppbbx24-del could promote anthocyanin accumulation in pear fruit peels,calli,and tobacco flowers.Due to the loss of nuclear localization sequence(NLS)and viral protein(VP)domains,Ppbbx24-del co-localized in the nucleus and cytoplasm,whereas PpBBX24 localized only in the nucleus.Real-time PCR and transcriptome analyses indicated that PpM YB10 and PpH Y5 are highly expressed in the‘Red Zaosu'pear.In yeast one-hybrid and dual-luciferase assays,Ppbbx24-del and PpHY5 independently promoted the expression of PpC HS,PpC HI,and PpM YB10 by binding to their promoters;however,PpBBX24 did not affect the expression of these genes.Additionally,we found that Ppbbx24-del and PpHY5 had additive effects on the expression of PpC HS,PpC HI,and PpMYB10,as they promote the expression of anthocyanin synthesis genes separately.The co-expression of PpB BX24 and PpHY5 inhibited the activation of downstream genes by PpHY5,which was attributed to the interaction between the two loci.In conclusion,our results clarify the molecular mechanism by which mutant Ppbbx24-del and PpBBX24 exert opposite effects in regulating anthocyanin accumulation in pear.These findings lay an important theoretical foundation for using Ppbbx24-del to create red pear cultivars.展开更多
Wearable sensors represent a promising technology to monitor human health and movement,however,it is pivotal and challenging to tailor-make highly conductive hydrogels to achieve high sensitivity and environmental wea...Wearable sensors represent a promising technology to monitor human health and movement,however,it is pivotal and challenging to tailor-make highly conductive hydrogels to achieve high sensitivity and environmental weatherability for application at extreme temperature conditions.Herein,the dual-conductive hydrogels consisting of ion-conductive deep eutectic solvents(DES)and electron-conductive MXene within polymer matrix have been presented.The increment of ion and electron migration path could generate substantial resistance variation and thus improves the sensitivity of hydrogels under small strain and large strain,resembling those in low and high frequency sound discrimination of auditory transduction.Additionally,the hydrogen bonding interactions among water molecules,DES and MXene as well as polymers endow the hydrogels with superior anti-freezing and water-retaining performance.The resultant hydrogel sensor achieves ultra-fast strain response time of 0.01 s and high sensitivity over 1.0 in wide strain ranges from 1%to 150%.High sensitivity,anti-freezing and water-retaining performance enable the hydrogels to monitor strain at extreme temperature conditions from20 to 60℃ and could detect human motion in real time.This work provides a rational approach to the construction of high-sensitivity and environmental weatherable hydrogels based on the dual-conductive fillers for the development of advanced wearable sensors.展开更多
An aromatic polyamide was synthesized by low-temperature poly-condensation reaction from terephthaloyl chloride and 4,4'-diaminobenzanilide (4,4'-DABA). The synthesized polyamide had a characteristic peak of c...An aromatic polyamide was synthesized by low-temperature poly-condensation reaction from terephthaloyl chloride and 4,4'-diaminobenzanilide (4,4'-DABA). The synthesized polyamide had a characteristic peak of carbon atoms in the amide group at 166 ppm, which was demonstrated by the solid nuclear magnetic resonance carbon spectrum. It was shown to be the stretching vibration absorption peak of the amide N-H bond at 3342 cm<sup>−1</sup> by Fourier infrared (FT-IR) spectroscopy. It was obtained that the energy band near 1100 - 1276 cm<sup>−1</sup> belongs to the absorption peak of the para-substituted benzene ring and the band near 2977 cm<sup>−1</sup> was the C-H stretching vibration peak of the benzene ring by Raman spectroscopy. The molecular structure of the synthesized polyamide compound was confirmed by FT-IR, Raman, and solid <sup>13</sup>C-NMR spectroscopies. It was proved that the polymer is stable up to 300˚C and has a relatively high stability by the thermogravimetric analysis. It was also confirmed by the fluorescence spectrum that it has a strong blue fluorescence near 420 nm. The morphological characteristics of the polymer were further demonstrated by electron scanning electron microscopy (SEM). The properties of polymeric p-benzoyl-4,4'-diaminobenzoyl-aniline were found to emit strong blue fluorescence and have good thermal stability, making it a promising functional material for fluorescence in the blue region with potential for large-scale applications.展开更多
An aromatic polyamide was synthesized by low-temperature poly-condensation reaction from terephthaloyl chloride and 4,4'-diaminobenzanilide (4,4'-DABA). The synthesized polyamide had a characteristic peak of c...An aromatic polyamide was synthesized by low-temperature poly-condensation reaction from terephthaloyl chloride and 4,4'-diaminobenzanilide (4,4'-DABA). The synthesized polyamide had a characteristic peak of carbon atoms in the amide group at 166 ppm, which was demonstrated by the solid nuclear magnetic resonance carbon spectrum. It was shown to be the stretching vibration absorption peak of the amide N-H bond at 3342 cm<sup>−1</sup> by Fourier infrared (FT-IR) spectroscopy. It was obtained that the energy band near 1100 - 1276 cm<sup>−1</sup> belongs to the absorption peak of the para-substituted benzene ring and the band near 2977 cm<sup>−1</sup> was the C-H stretching vibration peak of the benzene ring by Raman spectroscopy. The molecular structure of the synthesized polyamide compound was confirmed by FT-IR, Raman, and solid <sup>13</sup>C-NMR spectroscopies. It was proved that the polymer is stable up to 300˚C and has a relatively high stability by the thermogravimetric analysis. It was also confirmed by the fluorescence spectrum that it has a strong blue fluorescence near 420 nm. The morphological characteristics of the polymer were further demonstrated by electron scanning electron microscopy (SEM). The properties of polymeric p-benzoyl-4,4'-diaminobenzoyl-aniline were found to emit strong blue fluorescence and have good thermal stability, making it a promising functional material for fluorescence in the blue region with potential for large-scale applications.展开更多
Estrogen deficiency mediates aging, but the underlying mechanism remains to be fully determined. We report here that estrogen deficiency caused by targeted disruption of aromatase in mice results in significant inhibi...Estrogen deficiency mediates aging, but the underlying mechanism remains to be fully determined. We report here that estrogen deficiency caused by targeted disruption of aromatase in mice results in significant inhibition of telomerase activity in the adrenal gland in vivo. Gene expression analysis showed that, in the absence of estrogen, telomerase reverse transcriptase （TERT） gene expression is reduced in association with compromised cell proliferation in the adrenal gland cortex and adrenal atrophy. Stem cells positive in c-kit are identified to populate in the parenchyma of adrenal cortex. Analysis of telomeres revealed that estrogen deficiency results in significantly shorter teiomeres in the adrenal cortex than that in wild-type （WT） control mice. To further establish the causal effects of estrogen, we conducted an estrogen replacement therapy in these estrogen-deficient animals. Administration of estrogen for 3 weeks restores TERT gene expression, telomerase activity and cell proliferation in estrogen-deficient mice. Thus, our data show for the first time that estrogen deficiency causes inhibitions of TERT gene expression, telomerase activity, telomere maintenance, and cell proliferation in the adrenal gland of mice in vivo, suggesting that telomerase inhibition and telomere shortening may mediate cell proliferation arrest in the adrenal gland, thus contributing to estrogen deficiency-induced aging under physiological conditions.展开更多
With wide application of electric vehicles and large-scale in energy storage systems, the requirement ofsecondary batteries with higher power density and better safety gets urgent. Owing to the merits of hightheoretic...With wide application of electric vehicles and large-scale in energy storage systems, the requirement ofsecondary batteries with higher power density and better safety gets urgent. Owing to the merits of hightheoretical capacity, relatively low cost and suitable discharge voltage, much attention has been paid tothe transition metal sulfides. Recently, a large amount of research papers have reported about the appli-cation of transition metal sulfides in lithium ion batteries. However, the practical application of transitionmetal sulfides is still impeded by their fast capacity fading and poor rate performance. More well-focusedresearches should be operated towards the commercialization of transition metal sulfides in lithium ionbatteries. In this review, recent development of using transition metal sulfides such as copper sulfides,molybdenum sulfides, cobalt sulfides, and iron sulfides as electrode materials for lithium ion batteriesis presented. In addition, the electrochemical reaction mechanisms and synthetic strategy of transitionmetal sulfides are briefly summarized. The critical issues, challenges, and perspectives providing a fur-ther understanding of the associated electrochemical processes are also discussed.展开更多
Wellbore stability is essential for safe and efficient drilling during oil and gas exploration and development.This paper introduces a hydrophobic nano-silica(HNS)for use in strengthening the wellbore wall when using ...Wellbore stability is essential for safe and efficient drilling during oil and gas exploration and development.This paper introduces a hydrophobic nano-silica(HNS)for use in strengthening the wellbore wall when using a water-based drilling fluid(WBF).The wellbore-strengthening performance was studied using the linear swelling test,hot-rolling recovery test,and compressive strength test.The mechanism of strengthening the wellbore wall was studied by means of experiments on the zeta potential,particle size,contact angle,and surface tension,and with the use of a scanning electron microscope(SEM).The surface free energy changes of the shale before and after HNS treatment were also calculated using the contact angle method.The experimental results showed that HNS exhibited a good performance in inhibiting shale swelling and dispersion.Compared with the use of water,the use of HNS resulted in a 20%smaller linear swelling height of the bentonite pellets and an 11.53 times higher recovery of water-sensitive shale—a performance that exceeds those of the commonly used shale inhibitors KCl and polyamines.More importantly,the addition of HNS was effective in preventing a decrease in shale strength.According to the mechanism study,the good wellbore-strengthening performance of HNS can be attributed to three aspects.First,the positively charged HNS balances parts of the negative charges of clay by means of electrostatic adsorption,thus inhibiting osmotic hydration.Second,HNS fabricates a lotus-leaf-like surface with a micro-nano hierarchical structure on shale after adsorption,which significantly increases the water contact angle of the shale surface and considerably reduces the surface free energy,thereby inhibiting surface hydration.Third,the decrease in capillary action and the effective plugging of the shale pores reduce the invasion of water and promote wellbore stability.The approach described herein may provide an avenue for inhibiting both the surface hydration and the osmotic hydration of shale.展开更多
Fully reversed tensile-compression low-cycle fatigue tests were performed at room temperature under strain amplitude of 0.4%.The monotonic tensile results show that Fe-26Mn-10A1-C steels are fully austenite and(he opt...Fully reversed tensile-compression low-cycle fatigue tests were performed at room temperature under strain amplitude of 0.4%.The monotonic tensile results show that Fe-26Mn-10A1-C steels are fully austenite and(he optimal combination of ultimate tensile strength and total elongation was present at 950°C with 65 GPa%.The fatigue results show that the specimen at 1050°C has the maximum fatigue life of 162,000 cycles,which is much longer than twinning-induced plasticity(TWIP)steels of the same strain amplitude.The hot-forging specimen shows high similarity with TWIP steels with rapid initial cyclic hardening followed by cyclic softening and cyclic saturation.After solution heat treatment,it is noteworthy that,after rapid initial cyclic softening,another rapid cyclic hardening and a following decrease with fluctuation were observed at 1000°C.It is reas on able to believe that it is caused by K-carbides precipitated during cyclic deformation.Anolher interesting phenomenon is cyclic stress subsidence observed at 1050°C during its saturation stage at the last quarter of the fatigue life,and the span is about 12.5%of whole fatigue life.展开更多
Wellbore instability,especially drilling with water-based drilling fluids(WBDFs)in complex shale for-mations,is a critical challenge for oil and gas development.The purpose of this paper is to study the feasibility of...Wellbore instability,especially drilling with water-based drilling fluids(WBDFs)in complex shale for-mations,is a critical challenge for oil and gas development.The purpose of this paper is to study the feasibility of using hydrophobically modified silica nanoparticle(HMN)to enhance the comprehensive performance of WBDFs in the Xinjiang Oilfield,especially the anti-collapse performance.The effect of HMN on the overall performance of WBDFs in the Xinjiang Oilfield,including inhibition,plugging,lu-bricity,rheology,and filtration loss,was studied with a series of experiments.The mechanism of HMN action was studied by analyzing the changes of shale surface structure and chemical groups,wettability,and capillary force.The experimental results showed that HMN could improve the performance of WBDFs in the Xinjiang Oilfeld to inhibit the hydration swelling and dispersion of shale.The plugging and lubrication performance of the WBDFs in the Xinjiang Oilfield were also enhanced with HMN based on the experimental results.HMN had less impact on the rheological and filtration performance of the WBDFs in the Xinjiang Oilfield.In addition,HMN significantly prevented the decrease of shale strength.The potential mechanism of HMN was as follows.The chemical composition and structure of the shale surface were altered due to the adsorption of HMN driven by electrostatic attraction.Changes of the shale surface resulted in significant wettability transition.The capillary force of the shale was converted from a driving force of water into the interior to a resistance.In summary,hydrophobic nanoparticles presented afavorable application potential for WBDFs.展开更多
Previous studies on optical remote sensing mapping of landslides mainly focused on new landslides that have occurred, but little attention was paid to the early landslide due to its high concealment. In SAR technology...Previous studies on optical remote sensing mapping of landslides mainly focused on new landslides that have occurred, but little attention was paid to the early landslide due to its high concealment. In SAR technology, a prevalent method to detect early landslides, only can be used to identify the potential hazards of slow deformation. Therefore, it is necessary to explore new method of early landslides mapping by integrating all types of direct and indirect early features, such as cracks on slopes, small collapses inside and topographic features. In this study, an object-oriented image analysis method based on slope unit division and multi-scale segmentation was proposed to obtain accurate location and boundary extraction of early landslides. In the middle-and small-scale segmentation, the object, texture, spectrum, geometric features,topographic features, and other features were obtained to determine the local feature location of early landslides. The slope unit boundary was combined with the feature of a large-scale segmentation object to determine the scope of landslides. This method was tested in the Xianshui River basin in the Daofu County, Sichuan Province, China. The results demonstrate that:(1) Such features as landslide cracks and the small collapse at the bottom of slope can effectively determine the landslide position.(2) The slope unit division and the correct setting of shape factors in multiple segmentation can effectively determine the landslide boundary.(3) The accuracy of landslide location extraction was 83.33%, and the accuracy of boundary extraction for early landslides that were completely identified was evaluated as 82.67%. It is indicated that this method can improve the accuracy of boundary extraction and meet the requirements of the early landslides mapping.展开更多
Early Cretaceous A-type granitic plutons are widely distributed in Shandong Peninsula,which are of great significance to understanding the regional tectonic evolution.Here we report geochemical characteristics,geochro...Early Cretaceous A-type granitic plutons are widely distributed in Shandong Peninsula,which are of great significance to understanding the regional tectonic evolution.Here we report geochemical characteristics,geochronological results,and zircon Hf-O isotope compositions of Wulian granites to reveal its origin and geological significance.Wulian granites share most characteristics of the A_(2)-type granite.Zircon U-Pb LA-ICPMS analysis for Wulian A-type granites yields average age of 116.6±2.1 Ma.Zircon O isotope values range from 4.20‰to 5.57‰,and these values are marginally identical to or slightly lower than those of mantle zircon(5.3‰±0.3‰).Zirconε_(Hf)(t)values(-26.1--23.5)indicate an enriched source.Integrated zircon Hf-O isotope compositions indicate that the source region of Wulian granites involves the components of ancient oceanic crust.Apatites from Wulian granites have the lower chlorine(0.06 wt.%-0.15 wt.%)and higher fluorine contents(2.11 wt.%-2.48 wt.%)compared with Haiyang pluton,together with their high(La/Gd)_(N),(La/Yd)_(N) and low(Gd/Yb)_(N) ratios and high oxygen state magma reflected from zircon,signifying that slab derived component was added into the overlying mantle region through fluid/melt.The geochemical characteristics of Wulian granites could be explained by the ridge(between the Izanagi and Pacific plates)subduction model,which began to influence the tectonic evolution of the Xuhuai region and Shandong Peninsula since~130±5 Ma.The following slab window between two plates plausibly explains regional extension,resulting in hot magma upwelling and the formation of the A-type granite belt.Integrating the Lower Yangtze River belt and Shandong Peninsula A-type granite proves the northward movement of the ridge between the Pacific Plate and Izanagi Plate.展开更多
Hydraulic slotting in a gas drainage borehole is an effective method of enhancing gas drainage perfor- mance. However, it frequently occurs that a large amount of slotting products （mainly the coal slurry and gas） i...Hydraulic slotting in a gas drainage borehole is an effective method of enhancing gas drainage perfor- mance. However, it frequently occurs that a large amount of slotting products （mainly the coal slurry and gas） intensely spurt out of the borehole during the slotting, which adversely affects the slotting efficiency. Despite extensive previous investigations on the mechanism and prevention-device design of the spurt during ordinary borehole drilling, a very few studies has focused on the spurt in the s Ottlng pro ] ＂ _ cess. The slotting spurt is mainly caused by two reasons： the coal and gas outburst in the borehole and the borehole deslagging blockage. This paper focuses on the second reason, and investigates the hydraulic deslagging flow patterns in the annular space between the drill pipe and borehole wall Results show that there are six deslagging flow patterns when the drill pipe is still： pure slurry flow, pure gas flow, bubble flow, intermittent flow, layering flow and annular flow. When the drill pipe rotates, each of those six flow patterns changes due to the Taylor vortex effect. Outcomes of this study could help to better understand the slotting-spurt mechanism and provide guidance on the anti-spurt strategies through eliminating the borehole deslagging blockage.展开更多
Based on single-cell sequencing of the hippocampi of 5×familiar Alzheimer's disease(5×FAD)and wild type mice at 2-,12-,and 24-month of age,we found an increased percentage of microglia in aging and Alzhe...Based on single-cell sequencing of the hippocampi of 5×familiar Alzheimer's disease(5×FAD)and wild type mice at 2-,12-,and 24-month of age,we found an increased percentage of microglia in aging and Alzheimer's disease(AD)mice.Blood brain barrier injury may also have contributed to this increase.Immune regulation by microglia plays a major role in the progression of aging and AD,according to the functions of 41 intersecting differentially expressed genes in microglia.Signaling crosstalk between C−C motif chemokine ligand(CCL)and major histocompatibility complex-1 bridges intercellular communication in the hippocampus during aging and AD.The amyloid precursor protein(APP)and colony stimulating factor(CSF)signals drive 5×FAD to deviate from aging track to AD occurrence among intercellular communication in hippocampus.Microglia are involved in the progression of aging and AD can be divided into 10 functional types.The strength of the interaction among microglial subtypes weakened with aging,and the CCL and CSF signaling pathways were the fundamental bridge of communication among microglial subtypes.展开更多
Conventional quantity determination of Chinese herbal medicines by High-Performance Thin-Layer Chromatography (HPTLC) must be carried out on a TLC scanner for measuring the marker component on the HPTLC plate. General...Conventional quantity determination of Chinese herbal medicines by High-Performance Thin-Layer Chromatography (HPTLC) must be carried out on a TLC scanner for measuring the marker component on the HPTLC plate. Generally the HPTLC image of the herbal drug always takes the photograph as the permanent visual document. Considering the photo of the HPTLC image preserving all the visual quality-related parameters, there might be an alternative cost/effective approach worth studying. It would be presumably applicable to use the exclusively developed software as a virtual scanner instead of the TLC Scanner instrument to do digital scanning, integrating and calculating target components in the photo of the HPTLC image. It means digitally scanning the photo of the HPTLC image solely with software does the same thing as the instrumental scanner does. Based on this protocol, we primarily conducted the assay of the contents of the major saponins, jujuboside a and jujuboside b, in Ziziphi Spinosae Semen (Suan-Zao-Ren). Using home-developed software “digiscan” for acquiring the raw data and integrating the peaks area of the target components with “Origin Pro”, the contents of jujuboside a and jujuboside b can then be calculated respectively. The primary investigated experiment results were well compatible with official HPLC-ELSD method in Chinese Pharmacopoeia. The methodology validation and comparative analysis with HPLC confirmed that the unprecedented method is acceptable. The advantage of the recommended approach is far more simple, flexible and cost/effective than the conventional method, and it can be done at anytime and anywhere once only if the high quality HPTLC image photo is available. There would be a bright perspective for application to other herbal medicines. And the one-stop software for merging digital scanning, integration and calculation together is in progress.展开更多
Predicting the responses of an alluvial channel to changes in flow and sediment supply is essential for engineering design. Many methods have been developed in the last few decades to describe sectional bankfull chara...Predicting the responses of an alluvial channel to changes in flow and sediment supply is essential for engineering design. Many methods have been developed in the last few decades to describe sectional bankfull characteristics(elevation and discharge); however, studies on long-term reach-scale bankfull discharge are still limited. In this study, a hydraulic model is built to calculate the reach-scale bankfull discharge, and the effects of reservoir building on downstream bankfull discharges are discussed. The studied river reach is located at the lower Wei River(WR), where the planned Dongzhuang Reservoir would be built on its largest tributary, the Jing River. A quasi-two-dimensional numerical model coupled with a bankfull discharge estimating method is put forward to calculate the reach-scale bankfull discharge. The soundness of the model is verified. Results show that the temporal variation of reach-scale bankfull discharge of the lower reach of the WR would be highly influenced by the planned reservoir, especially during the first 20 years of operation. The effect of the planned reservoir on bankfull discharge may reach its maximum when the total trapped sediment load reaches approximately 75% of the reservoir capacity. Our results show that after the first 17 years of operation,the effect of the planned reservoir on bankfull discharge of the river reach may decrease gradually.The soundness and predictive capability of the coupled model have also been calibrated by comparing with existing reservoirs. All analyses indicate that the numerical model can be used to predict the changed reach-scale bankfull discharge of the lower WR.展开更多
It is always highly pursued to develop efficient and durable catalysts for catalytic applications.Herein,intermetallic PdBi aerogels with tunable activity were prepared successfully via a surfactant-free spontaneous g...It is always highly pursued to develop efficient and durable catalysts for catalytic applications.Herein,intermetallic PdBi aerogels with tunable activity were prepared successfully via a surfactant-free spontaneous gelation process.The prepared PdBi aerogels have a three-dimensional high porous structure and plentiful active sites pervaded on the ultrathin interlinked nanowires network.These unique structures,as well as the synergistic effect between Pd and Bi,can accelerate mass and electron transfer,and improve the atom utilization ratio of Pd atoms to promote the catalytic efficiency.As a proofof-concept application,the optimized Pd_(2) Bi_(1) aerogels exhibit 4.2 and 6.2 times higher catalytic activity for the reduction of 4-nitrophenol(4-NP)and methylene blue(MB)than those of commercial Pd/C,respectively.With the introduction of non-noble metal of Bi,the cost of the resulted Pd Bi aerogels can be dropped signi ficantly while the catalytic capability of Pd Bi aerogel will be improved sharply.This strategy will bring good hints to rationally design fine catalysts for various applications.展开更多
Organic-inorganic hybrid materials provide a desirable platform for the development of novel functional materials.Here,we report the one-pot synthesis of mesoporous hybrid nanospheres by the in-situ sol-gel condensati...Organic-inorganic hybrid materials provide a desirable platform for the development of novel functional materials.Here,we report the one-pot synthesis of mesoporous hybrid nanospheres by the in-situ sol-gel condensation of tetraethoxysilane around surfactant micelle-confined nano covalent organic polymer(nanoCOP)colloids.The hybrid nanospheres containing nanoCOPs uniformly distributed in the mesosilica network,inherited the visible light responsive properties of the nanoCOPs.The turnover frequency of the hybrid nanospheres is almost 12 times that of its corresponding bulk COP counterpart for the photocatalytic reductive dehalogenation of a-bromoacetophenone,which is attributed to activation of the Hantzsch ester reductant by the hydroxyl group.The existence of a volcano relationship between the activity and nano COP/mesosilica ratio confirmed the synergistic effect between nano COP and mesosilica.Our preliminary results suggest that hybridization of semiconductors and reactant-activating materials is an efficient strategy for enhancing the activity of a catalyst for photocatalysis.展开更多
The development of heterogeneous catalytic processes is crucial for the synthesis of chiral compounds for both academic and industrial applications.However,thus far,such achievements have remained elusive.Herein,we re...The development of heterogeneous catalytic processes is crucial for the synthesis of chiral compounds for both academic and industrial applications.However,thus far,such achievements have remained elusive.Herein,we report the heterogeneous asymmetric hydrogenation of 2-methylquinoline over solid chiral catalysts,which were prepared by the one-pot polymerization of(1R,2R)-N-(4-vinyl-benzenesulfonyl)-1,2-diphenylethane-1,2-diamine(VDPEN)and divinylbenzene(DVB)in the presence or absence of activated carbon(C)or carbon nanotubes(CNTs),followed by Ru coordination and anion exchange.The solid chiral catalysts were fully characterized by N2 sorption analysis,elemental analysis,TEM,FT-IR spectroscopy,and 13C CP-MAS NMR.All the solid chiral catalysts could efficiently catalyze the asymmetric hydrogenation of 2-methylquinoline to afford 2-methyl-1,2,3,4-tetrahydroquinoline with 90%ee.Studies have shown that polymer/C and polymer/CNTs composites are more active than pure polymers.The polymer/CNTs composite exhibited the highest activity among all the solid chiral catalysts under identical conditions,owing to the unique morphology of CNTs.The recycling stabilities of the solid chiral catalysts were greatly improved when ionic liquids(ILs)were employed as solvents;this is mainly attributed to the decreased leaching amount of anions owing to the confinement effect of ILs on ionic compounds.展开更多
Marine microorganism accumulated on the surface of ships or pipelines would accelerate fouling organisms, such as mussels and barnacles, adhered on the surface. It was significant to understand the bio-interaction bet...Marine microorganism accumulated on the surface of ships or pipelines would accelerate fouling organisms, such as mussels and barnacles, adhered on the surface. It was significant to understand the bio-interaction between the microorganisms and the surface. Attenuated total reflection(ATR) Fourier transform infrared(FTIR) spectroscopy was used to study the initial stages of marine microorganism adhering to surfaces, because it could probe the microorganism interaction to the surface regardless of the water interference. Bacillus sp. and Escherichia coli were selected to study the initial attachment on different surfaces, because they were typical fouling microorganisms and showed opposite Gram stain results. The assays were conducted respectively in dried and settled bacteria on two different surfaces(ZnSe, Al2 O3 coated on ZnSe). IR spectra of settled bacteria showed amide I band red shift and amide II band blue shift in aqueous environment on both surfaces compared with the dry bacteria. The reasons of amide bands shift were investigated and it was discovered that the hydrogen bond between the water and the protein of the bacteria led to the protein secondary structure change. ATR-FTIR provided an approach to study the attachment process and showed dynamic changing process on the surface, and it could be an appropriate approach to study the interaction between proteins and chemicals.展开更多
基金Sponsored by Campus Culture Project of Beijing Jiaotong University:Cross-cultural Study of Campus Official English Translation from the Perspective of International Publicity (162085522)。
文摘The linguistic landscape of traditional historic tourist attractions has undergone heterogeneous changes under the impact of globalization and tourism development.Guided by the linguistic landscape construction principle and meaning combination analysis,taking the linguistic landscape of South Luogu Al ey in Beijing as the research object,its unique presentation and formation mechanism are analyzed and explicated in this paper.In the first part,we describe the elements of tradition and modernity presented in both private and official linguistic landscape.In the second part,we explain these characteristics,and the results show that:traditional elements dominated with each presents unique characteristics while modern elements especially English have been extensively employed than ever before,functioning as the information disseminator and prestige symbol.Finally,certain degrees of problems need to be meticulously considered so as to foster the renewal progress of the historic tourist attractions.
基金National Natural Science Foundation of China(32072531)the Agricultural Science and Technology Innovation Program of the Chinese Academy of Agricultural Sciences(CAAS-ASTIP-2016-RIP)+2 种基金the National Key Research and Development Program of China(2021YFE0190700)the ScienceTechnology&Innovation Funding Authority(STDF)of Egypt(43093)for funding this work。
文摘Red fruit peel is one of pear's most valuable economic traits and is mainly determined by anthocyanins.Many pear cultivars with a red peel originated from bud sports;however,little is known about the genetic mechanisms underlying this trait.We have previously identified a mutant Pp BBX24 containing a 14-nucleotide deletion in the coding region(Ppbbx24-del)as the only known variant associated with the red coloration of the mutant‘Red Zaosu'pear(Pyrus pyrifolia White Pear Group).Herein,we analyzed the role of the mutant gene in red coloration and its mechanism of action.The results showed that light promoted red peel coloration in the‘Red Zaosu'pear,and Ppbbx24-del positively affected light-induced anthocyanin biosynthesis,while normal Pp BBX24 had the opposite effects.Transient and stable transformation experiments confirmed that Ppbbx24-del could promote anthocyanin accumulation in pear fruit peels,calli,and tobacco flowers.Due to the loss of nuclear localization sequence(NLS)and viral protein(VP)domains,Ppbbx24-del co-localized in the nucleus and cytoplasm,whereas PpBBX24 localized only in the nucleus.Real-time PCR and transcriptome analyses indicated that PpM YB10 and PpH Y5 are highly expressed in the‘Red Zaosu'pear.In yeast one-hybrid and dual-luciferase assays,Ppbbx24-del and PpHY5 independently promoted the expression of PpC HS,PpC HI,and PpM YB10 by binding to their promoters;however,PpBBX24 did not affect the expression of these genes.Additionally,we found that Ppbbx24-del and PpHY5 had additive effects on the expression of PpC HS,PpC HI,and PpMYB10,as they promote the expression of anthocyanin synthesis genes separately.The co-expression of PpB BX24 and PpHY5 inhibited the activation of downstream genes by PpHY5,which was attributed to the interaction between the two loci.In conclusion,our results clarify the molecular mechanism by which mutant Ppbbx24-del and PpBBX24 exert opposite effects in regulating anthocyanin accumulation in pear.These findings lay an important theoretical foundation for using Ppbbx24-del to create red pear cultivars.
基金the funding support from the National Natural Science Foundation of China(22471055)Scientific Research Projects of Higher Education Institutions in Hebei Province(BJ2025137)+3 种基金Natural Science Foundation of Hebei Province(B2024202020,B2022202039)Hebei Yanzhao Golden Platform Talents Project(B2024003001)State Key Laboratory of Structural Chemistry(20240025)Tianjin Education Commission Scientific Research Project(2022KJ093).
文摘Wearable sensors represent a promising technology to monitor human health and movement,however,it is pivotal and challenging to tailor-make highly conductive hydrogels to achieve high sensitivity and environmental weatherability for application at extreme temperature conditions.Herein,the dual-conductive hydrogels consisting of ion-conductive deep eutectic solvents(DES)and electron-conductive MXene within polymer matrix have been presented.The increment of ion and electron migration path could generate substantial resistance variation and thus improves the sensitivity of hydrogels under small strain and large strain,resembling those in low and high frequency sound discrimination of auditory transduction.Additionally,the hydrogen bonding interactions among water molecules,DES and MXene as well as polymers endow the hydrogels with superior anti-freezing and water-retaining performance.The resultant hydrogel sensor achieves ultra-fast strain response time of 0.01 s and high sensitivity over 1.0 in wide strain ranges from 1%to 150%.High sensitivity,anti-freezing and water-retaining performance enable the hydrogels to monitor strain at extreme temperature conditions from20 to 60℃ and could detect human motion in real time.This work provides a rational approach to the construction of high-sensitivity and environmental weatherable hydrogels based on the dual-conductive fillers for the development of advanced wearable sensors.
文摘An aromatic polyamide was synthesized by low-temperature poly-condensation reaction from terephthaloyl chloride and 4,4'-diaminobenzanilide (4,4'-DABA). The synthesized polyamide had a characteristic peak of carbon atoms in the amide group at 166 ppm, which was demonstrated by the solid nuclear magnetic resonance carbon spectrum. It was shown to be the stretching vibration absorption peak of the amide N-H bond at 3342 cm<sup>−1</sup> by Fourier infrared (FT-IR) spectroscopy. It was obtained that the energy band near 1100 - 1276 cm<sup>−1</sup> belongs to the absorption peak of the para-substituted benzene ring and the band near 2977 cm<sup>−1</sup> was the C-H stretching vibration peak of the benzene ring by Raman spectroscopy. The molecular structure of the synthesized polyamide compound was confirmed by FT-IR, Raman, and solid <sup>13</sup>C-NMR spectroscopies. It was proved that the polymer is stable up to 300˚C and has a relatively high stability by the thermogravimetric analysis. It was also confirmed by the fluorescence spectrum that it has a strong blue fluorescence near 420 nm. The morphological characteristics of the polymer were further demonstrated by electron scanning electron microscopy (SEM). The properties of polymeric p-benzoyl-4,4'-diaminobenzoyl-aniline were found to emit strong blue fluorescence and have good thermal stability, making it a promising functional material for fluorescence in the blue region with potential for large-scale applications.
文摘An aromatic polyamide was synthesized by low-temperature poly-condensation reaction from terephthaloyl chloride and 4,4'-diaminobenzanilide (4,4'-DABA). The synthesized polyamide had a characteristic peak of carbon atoms in the amide group at 166 ppm, which was demonstrated by the solid nuclear magnetic resonance carbon spectrum. It was shown to be the stretching vibration absorption peak of the amide N-H bond at 3342 cm<sup>−1</sup> by Fourier infrared (FT-IR) spectroscopy. It was obtained that the energy band near 1100 - 1276 cm<sup>−1</sup> belongs to the absorption peak of the para-substituted benzene ring and the band near 2977 cm<sup>−1</sup> was the C-H stretching vibration peak of the benzene ring by Raman spectroscopy. The molecular structure of the synthesized polyamide compound was confirmed by FT-IR, Raman, and solid <sup>13</sup>C-NMR spectroscopies. It was proved that the polymer is stable up to 300˚C and has a relatively high stability by the thermogravimetric analysis. It was also confirmed by the fluorescence spectrum that it has a strong blue fluorescence near 420 nm. The morphological characteristics of the polymer were further demonstrated by electron scanning electron microscopy (SEM). The properties of polymeric p-benzoyl-4,4'-diaminobenzoyl-aniline were found to emit strong blue fluorescence and have good thermal stability, making it a promising functional material for fluorescence in the blue region with potential for large-scale applications.
文摘Estrogen deficiency mediates aging, but the underlying mechanism remains to be fully determined. We report here that estrogen deficiency caused by targeted disruption of aromatase in mice results in significant inhibition of telomerase activity in the adrenal gland in vivo. Gene expression analysis showed that, in the absence of estrogen, telomerase reverse transcriptase （TERT） gene expression is reduced in association with compromised cell proliferation in the adrenal gland cortex and adrenal atrophy. Stem cells positive in c-kit are identified to populate in the parenchyma of adrenal cortex. Analysis of telomeres revealed that estrogen deficiency results in significantly shorter teiomeres in the adrenal cortex than that in wild-type （WT） control mice. To further establish the causal effects of estrogen, we conducted an estrogen replacement therapy in these estrogen-deficient animals. Administration of estrogen for 3 weeks restores TERT gene expression, telomerase activity and cell proliferation in estrogen-deficient mice. Thus, our data show for the first time that estrogen deficiency causes inhibitions of TERT gene expression, telomerase activity, telomere maintenance, and cell proliferation in the adrenal gland of mice in vivo, suggesting that telomerase inhibition and telomere shortening may mediate cell proliferation arrest in the adrenal gland, thus contributing to estrogen deficiency-induced aging under physiological conditions.
基金the financial support of the National Natural Science Foundation of China (21273185 and 21621091)the National Found for Fostering Talents of Basic Science (J1310024)
文摘With wide application of electric vehicles and large-scale in energy storage systems, the requirement ofsecondary batteries with higher power density and better safety gets urgent. Owing to the merits of hightheoretical capacity, relatively low cost and suitable discharge voltage, much attention has been paid tothe transition metal sulfides. Recently, a large amount of research papers have reported about the appli-cation of transition metal sulfides in lithium ion batteries. However, the practical application of transitionmetal sulfides is still impeded by their fast capacity fading and poor rate performance. More well-focusedresearches should be operated towards the commercialization of transition metal sulfides in lithium ionbatteries. In this review, recent development of using transition metal sulfides such as copper sulfides,molybdenum sulfides, cobalt sulfides, and iron sulfides as electrode materials for lithium ion batteriesis presented. In addition, the electrochemical reaction mechanisms and synthetic strategy of transitionmetal sulfides are briefly summarized. The critical issues, challenges, and perspectives providing a fur-ther understanding of the associated electrochemical processes are also discussed.
基金the National Natural Science Foundation of China (U1762212 and 51904329)the Shandong Natural Science Foundation (ZR2019BEE002)
文摘Wellbore stability is essential for safe and efficient drilling during oil and gas exploration and development.This paper introduces a hydrophobic nano-silica(HNS)for use in strengthening the wellbore wall when using a water-based drilling fluid(WBF).The wellbore-strengthening performance was studied using the linear swelling test,hot-rolling recovery test,and compressive strength test.The mechanism of strengthening the wellbore wall was studied by means of experiments on the zeta potential,particle size,contact angle,and surface tension,and with the use of a scanning electron microscope(SEM).The surface free energy changes of the shale before and after HNS treatment were also calculated using the contact angle method.The experimental results showed that HNS exhibited a good performance in inhibiting shale swelling and dispersion.Compared with the use of water,the use of HNS resulted in a 20%smaller linear swelling height of the bentonite pellets and an 11.53 times higher recovery of water-sensitive shale—a performance that exceeds those of the commonly used shale inhibitors KCl and polyamines.More importantly,the addition of HNS was effective in preventing a decrease in shale strength.According to the mechanism study,the good wellbore-strengthening performance of HNS can be attributed to three aspects.First,the positively charged HNS balances parts of the negative charges of clay by means of electrostatic adsorption,thus inhibiting osmotic hydration.Second,HNS fabricates a lotus-leaf-like surface with a micro-nano hierarchical structure on shale after adsorption,which significantly increases the water contact angle of the shale surface and considerably reduces the surface free energy,thereby inhibiting surface hydration.Third,the decrease in capillary action and the effective plugging of the shale pores reduce the invasion of water and promote wellbore stability.The approach described herein may provide an avenue for inhibiting both the surface hydration and the osmotic hydration of shale.
文摘Fully reversed tensile-compression low-cycle fatigue tests were performed at room temperature under strain amplitude of 0.4%.The monotonic tensile results show that Fe-26Mn-10A1-C steels are fully austenite and(he optimal combination of ultimate tensile strength and total elongation was present at 950°C with 65 GPa%.The fatigue results show that the specimen at 1050°C has the maximum fatigue life of 162,000 cycles,which is much longer than twinning-induced plasticity(TWIP)steels of the same strain amplitude.The hot-forging specimen shows high similarity with TWIP steels with rapid initial cyclic hardening followed by cyclic softening and cyclic saturation.After solution heat treatment,it is noteworthy that,after rapid initial cyclic softening,another rapid cyclic hardening and a following decrease with fluctuation were observed at 1000°C.It is reas on able to believe that it is caused by K-carbides precipitated during cyclic deformation.Anolher interesting phenomenon is cyclic stress subsidence observed at 1050°C during its saturation stage at the last quarter of the fatigue life,and the span is about 12.5%of whole fatigue life.
基金the National Natural Science Foundation of China(51904329,52174014)the Major Scientific and Technological Projects of CNPC(ZD 2019-183-005)Key R&D Program of Shandong Province(No.2020ZLYS07).
文摘Wellbore instability,especially drilling with water-based drilling fluids(WBDFs)in complex shale for-mations,is a critical challenge for oil and gas development.The purpose of this paper is to study the feasibility of using hydrophobically modified silica nanoparticle(HMN)to enhance the comprehensive performance of WBDFs in the Xinjiang Oilfield,especially the anti-collapse performance.The effect of HMN on the overall performance of WBDFs in the Xinjiang Oilfield,including inhibition,plugging,lu-bricity,rheology,and filtration loss,was studied with a series of experiments.The mechanism of HMN action was studied by analyzing the changes of shale surface structure and chemical groups,wettability,and capillary force.The experimental results showed that HMN could improve the performance of WBDFs in the Xinjiang Oilfeld to inhibit the hydration swelling and dispersion of shale.The plugging and lubrication performance of the WBDFs in the Xinjiang Oilfield were also enhanced with HMN based on the experimental results.HMN had less impact on the rheological and filtration performance of the WBDFs in the Xinjiang Oilfield.In addition,HMN significantly prevented the decrease of shale strength.The potential mechanism of HMN was as follows.The chemical composition and structure of the shale surface were altered due to the adsorption of HMN driven by electrostatic attraction.Changes of the shale surface resulted in significant wettability transition.The capillary force of the shale was converted from a driving force of water into the interior to a resistance.In summary,hydrophobic nanoparticles presented afavorable application potential for WBDFs.
基金supported by Geological Survey Project of China Geological Survey(No.DD20221635,DD20211386,DD20211392,DD2019064,DD20190033,DD20179603,)the National Natural Science Foundation of China(No.92055314)。
文摘Previous studies on optical remote sensing mapping of landslides mainly focused on new landslides that have occurred, but little attention was paid to the early landslide due to its high concealment. In SAR technology, a prevalent method to detect early landslides, only can be used to identify the potential hazards of slow deformation. Therefore, it is necessary to explore new method of early landslides mapping by integrating all types of direct and indirect early features, such as cracks on slopes, small collapses inside and topographic features. In this study, an object-oriented image analysis method based on slope unit division and multi-scale segmentation was proposed to obtain accurate location and boundary extraction of early landslides. In the middle-and small-scale segmentation, the object, texture, spectrum, geometric features,topographic features, and other features were obtained to determine the local feature location of early landslides. The slope unit boundary was combined with the feature of a large-scale segmentation object to determine the scope of landslides. This method was tested in the Xianshui River basin in the Daofu County, Sichuan Province, China. The results demonstrate that:(1) Such features as landslide cracks and the small collapse at the bottom of slope can effectively determine the landslide position.(2) The slope unit division and the correct setting of shape factors in multiple segmentation can effectively determine the landslide boundary.(3) The accuracy of landslide location extraction was 83.33%, and the accuracy of boundary extraction for early landslides that were completely identified was evaluated as 82.67%. It is indicated that this method can improve the accuracy of boundary extraction and meet the requirements of the early landslides mapping.
基金supported by the National Natural Science Foundation of China(No.91958110)the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB42020203)。
文摘Early Cretaceous A-type granitic plutons are widely distributed in Shandong Peninsula,which are of great significance to understanding the regional tectonic evolution.Here we report geochemical characteristics,geochronological results,and zircon Hf-O isotope compositions of Wulian granites to reveal its origin and geological significance.Wulian granites share most characteristics of the A_(2)-type granite.Zircon U-Pb LA-ICPMS analysis for Wulian A-type granites yields average age of 116.6±2.1 Ma.Zircon O isotope values range from 4.20‰to 5.57‰,and these values are marginally identical to or slightly lower than those of mantle zircon(5.3‰±0.3‰).Zirconε_(Hf)(t)values(-26.1--23.5)indicate an enriched source.Integrated zircon Hf-O isotope compositions indicate that the source region of Wulian granites involves the components of ancient oceanic crust.Apatites from Wulian granites have the lower chlorine(0.06 wt.%-0.15 wt.%)and higher fluorine contents(2.11 wt.%-2.48 wt.%)compared with Haiyang pluton,together with their high(La/Gd)_(N),(La/Yd)_(N) and low(Gd/Yb)_(N) ratios and high oxygen state magma reflected from zircon,signifying that slab derived component was added into the overlying mantle region through fluid/melt.The geochemical characteristics of Wulian granites could be explained by the ridge(between the Izanagi and Pacific plates)subduction model,which began to influence the tectonic evolution of the Xuhuai region and Shandong Peninsula since~130±5 Ma.The following slab window between two plates plausibly explains regional extension,resulting in hot magma upwelling and the formation of the A-type granite belt.Integrating the Lower Yangtze River belt and Shandong Peninsula A-type granite proves the northward movement of the ridge between the Pacific Plate and Izanagi Plate.
文摘Hydraulic slotting in a gas drainage borehole is an effective method of enhancing gas drainage perfor- mance. However, it frequently occurs that a large amount of slotting products （mainly the coal slurry and gas） intensely spurt out of the borehole during the slotting, which adversely affects the slotting efficiency. Despite extensive previous investigations on the mechanism and prevention-device design of the spurt during ordinary borehole drilling, a very few studies has focused on the spurt in the s Ottlng pro ] ＂ _ cess. The slotting spurt is mainly caused by two reasons： the coal and gas outburst in the borehole and the borehole deslagging blockage. This paper focuses on the second reason, and investigates the hydraulic deslagging flow patterns in the annular space between the drill pipe and borehole wall Results show that there are six deslagging flow patterns when the drill pipe is still： pure slurry flow, pure gas flow, bubble flow, intermittent flow, layering flow and annular flow. When the drill pipe rotates, each of those six flow patterns changes due to the Taylor vortex effect. Outcomes of this study could help to better understand the slotting-spurt mechanism and provide guidance on the anti-spurt strategies through eliminating the borehole deslagging blockage.
基金supported by grants from the Key R&D Plan of the Science and Technology Plan of Tibet Autonomous Region,China(Grant No.:XZ202201ZY0026G)the Science and Technology Cooperation Project of Shandong Provincial Department of Science and Technology for Counterpart Assistance to Tibet,China(Grant No.:YDZX2021083)+1 种基金the National Natural Science Foundation of China(Grant No.:82205078)the Natural Science Foundation of Shandong Province,China(Grant No.:ZR2021QH157).
文摘Based on single-cell sequencing of the hippocampi of 5×familiar Alzheimer's disease(5×FAD)and wild type mice at 2-,12-,and 24-month of age,we found an increased percentage of microglia in aging and Alzheimer's disease(AD)mice.Blood brain barrier injury may also have contributed to this increase.Immune regulation by microglia plays a major role in the progression of aging and AD,according to the functions of 41 intersecting differentially expressed genes in microglia.Signaling crosstalk between C−C motif chemokine ligand(CCL)and major histocompatibility complex-1 bridges intercellular communication in the hippocampus during aging and AD.The amyloid precursor protein(APP)and colony stimulating factor(CSF)signals drive 5×FAD to deviate from aging track to AD occurrence among intercellular communication in hippocampus.Microglia are involved in the progression of aging and AD can be divided into 10 functional types.The strength of the interaction among microglial subtypes weakened with aging,and the CCL and CSF signaling pathways were the fundamental bridge of communication among microglial subtypes.
文摘Conventional quantity determination of Chinese herbal medicines by High-Performance Thin-Layer Chromatography (HPTLC) must be carried out on a TLC scanner for measuring the marker component on the HPTLC plate. Generally the HPTLC image of the herbal drug always takes the photograph as the permanent visual document. Considering the photo of the HPTLC image preserving all the visual quality-related parameters, there might be an alternative cost/effective approach worth studying. It would be presumably applicable to use the exclusively developed software as a virtual scanner instead of the TLC Scanner instrument to do digital scanning, integrating and calculating target components in the photo of the HPTLC image. It means digitally scanning the photo of the HPTLC image solely with software does the same thing as the instrumental scanner does. Based on this protocol, we primarily conducted the assay of the contents of the major saponins, jujuboside a and jujuboside b, in Ziziphi Spinosae Semen (Suan-Zao-Ren). Using home-developed software “digiscan” for acquiring the raw data and integrating the peaks area of the target components with “Origin Pro”, the contents of jujuboside a and jujuboside b can then be calculated respectively. The primary investigated experiment results were well compatible with official HPLC-ELSD method in Chinese Pharmacopoeia. The methodology validation and comparative analysis with HPLC confirmed that the unprecedented method is acceptable. The advantage of the recommended approach is far more simple, flexible and cost/effective than the conventional method, and it can be done at anytime and anywhere once only if the high quality HPTLC image photo is available. There would be a bright perspective for application to other herbal medicines. And the one-stop software for merging digital scanning, integration and calculation together is in progress.
基金funded by the National Natural Science Foundation of China(Grants No.2011CB403305,51579230,51109198,41571005,and 51479179)
文摘Predicting the responses of an alluvial channel to changes in flow and sediment supply is essential for engineering design. Many methods have been developed in the last few decades to describe sectional bankfull characteristics(elevation and discharge); however, studies on long-term reach-scale bankfull discharge are still limited. In this study, a hydraulic model is built to calculate the reach-scale bankfull discharge, and the effects of reservoir building on downstream bankfull discharges are discussed. The studied river reach is located at the lower Wei River(WR), where the planned Dongzhuang Reservoir would be built on its largest tributary, the Jing River. A quasi-two-dimensional numerical model coupled with a bankfull discharge estimating method is put forward to calculate the reach-scale bankfull discharge. The soundness of the model is verified. Results show that the temporal variation of reach-scale bankfull discharge of the lower reach of the WR would be highly influenced by the planned reservoir, especially during the first 20 years of operation. The effect of the planned reservoir on bankfull discharge may reach its maximum when the total trapped sediment load reaches approximately 75% of the reservoir capacity. Our results show that after the first 17 years of operation,the effect of the planned reservoir on bankfull discharge of the river reach may decrease gradually.The soundness and predictive capability of the coupled model have also been calibrated by comparing with existing reservoirs. All analyses indicate that the numerical model can be used to predict the changed reach-scale bankfull discharge of the lower WR.
基金the financial support from the National Natural Science Foundation of China(Nos.21245007 and 81000976)the Natural Science Foundation of Shandong Province(No.ZR2017MB017)+1 种基金Scientific Start-up Research Fund of Chengdu University of Information Technology(No.KYTZ201714)the open fund of Innovation&Application Engineering Research Center for Mesoporous Materials of Shanxi Province(No.MMIA2019001)。
文摘It is always highly pursued to develop efficient and durable catalysts for catalytic applications.Herein,intermetallic PdBi aerogels with tunable activity were prepared successfully via a surfactant-free spontaneous gelation process.The prepared PdBi aerogels have a three-dimensional high porous structure and plentiful active sites pervaded on the ultrathin interlinked nanowires network.These unique structures,as well as the synergistic effect between Pd and Bi,can accelerate mass and electron transfer,and improve the atom utilization ratio of Pd atoms to promote the catalytic efficiency.As a proofof-concept application,the optimized Pd_(2) Bi_(1) aerogels exhibit 4.2 and 6.2 times higher catalytic activity for the reduction of 4-nitrophenol(4-NP)and methylene blue(MB)than those of commercial Pd/C,respectively.With the introduction of non-noble metal of Bi,the cost of the resulted Pd Bi aerogels can be dropped signi ficantly while the catalytic capability of Pd Bi aerogel will be improved sharply.This strategy will bring good hints to rationally design fine catalysts for various applications.
文摘Organic-inorganic hybrid materials provide a desirable platform for the development of novel functional materials.Here,we report the one-pot synthesis of mesoporous hybrid nanospheres by the in-situ sol-gel condensation of tetraethoxysilane around surfactant micelle-confined nano covalent organic polymer(nanoCOP)colloids.The hybrid nanospheres containing nanoCOPs uniformly distributed in the mesosilica network,inherited the visible light responsive properties of the nanoCOPs.The turnover frequency of the hybrid nanospheres is almost 12 times that of its corresponding bulk COP counterpart for the photocatalytic reductive dehalogenation of a-bromoacetophenone,which is attributed to activation of the Hantzsch ester reductant by the hydroxyl group.The existence of a volcano relationship between the activity and nano COP/mesosilica ratio confirmed the synergistic effect between nano COP and mesosilica.Our preliminary results suggest that hybridization of semiconductors and reactant-activating materials is an efficient strategy for enhancing the activity of a catalyst for photocatalysis.
基金supported by the National Natural Science Foundation of China (21733009, 21621063)the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB17020200)~~
文摘The development of heterogeneous catalytic processes is crucial for the synthesis of chiral compounds for both academic and industrial applications.However,thus far,such achievements have remained elusive.Herein,we report the heterogeneous asymmetric hydrogenation of 2-methylquinoline over solid chiral catalysts,which were prepared by the one-pot polymerization of(1R,2R)-N-(4-vinyl-benzenesulfonyl)-1,2-diphenylethane-1,2-diamine(VDPEN)and divinylbenzene(DVB)in the presence or absence of activated carbon(C)or carbon nanotubes(CNTs),followed by Ru coordination and anion exchange.The solid chiral catalysts were fully characterized by N2 sorption analysis,elemental analysis,TEM,FT-IR spectroscopy,and 13C CP-MAS NMR.All the solid chiral catalysts could efficiently catalyze the asymmetric hydrogenation of 2-methylquinoline to afford 2-methyl-1,2,3,4-tetrahydroquinoline with 90%ee.Studies have shown that polymer/C and polymer/CNTs composites are more active than pure polymers.The polymer/CNTs composite exhibited the highest activity among all the solid chiral catalysts under identical conditions,owing to the unique morphology of CNTs.The recycling stabilities of the solid chiral catalysts were greatly improved when ionic liquids(ILs)were employed as solvents;this is mainly attributed to the decreased leaching amount of anions owing to the confinement effect of ILs on ionic compounds.
基金supported by the National Natural Science Foundation of China (No. 21675165)
文摘Marine microorganism accumulated on the surface of ships or pipelines would accelerate fouling organisms, such as mussels and barnacles, adhered on the surface. It was significant to understand the bio-interaction between the microorganisms and the surface. Attenuated total reflection(ATR) Fourier transform infrared(FTIR) spectroscopy was used to study the initial stages of marine microorganism adhering to surfaces, because it could probe the microorganism interaction to the surface regardless of the water interference. Bacillus sp. and Escherichia coli were selected to study the initial attachment on different surfaces, because they were typical fouling microorganisms and showed opposite Gram stain results. The assays were conducted respectively in dried and settled bacteria on two different surfaces(ZnSe, Al2 O3 coated on ZnSe). IR spectra of settled bacteria showed amide I band red shift and amide II band blue shift in aqueous environment on both surfaces compared with the dry bacteria. The reasons of amide bands shift were investigated and it was discovered that the hydrogen bond between the water and the protein of the bacteria led to the protein secondary structure change. ATR-FTIR provided an approach to study the attachment process and showed dynamic changing process on the surface, and it could be an appropriate approach to study the interaction between proteins and chemicals.
