In this paper, we conduct research on the interactive training pattern and the applications on the modern emergency rescue training activities. In emergency rescue training linkage the ecological communities, importan...In this paper, we conduct research on the interactive training pattern and the applications on the modern emergency rescue training activities. In emergency rescue training linkage the ecological communities, important is not gathered themselves together, and not the size of the momentum and the strength that is not the amount of emergency rescue training linkage performance, important is the ecological communities each organic elements in the function of the cohesion, lies in the relationship between the organic elements in ecological communities, the construction and the development is the specific ecological communities in action elements of emergency rescue training, joint quality lies in the emergency rescue training. These contents are involved in the emergency rescue training linkage management model of concrete. Under this basis, we integrate the condition of the Hainan Medical School to propose the corresponding suggestions that will enhance the performance.展开更多
Objective The thrombospondin-4(TSP-4)gene G29926C(A387P)polymorphism was recently reported to be associated with an increased risk for MI(myocardial infarction)in the American population.However,several subsequent stu...Objective The thrombospondin-4(TSP-4)gene G29926C(A387P)polymorphism was recently reported to be associated with an increased risk for MI(myocardial infarction)in the American population.However,several subsequent studies produced controversial findings.The aim of this study was to explore the possible association of the TSP-4 A387P polymorphism with ACS(acute coronary syndrome)in a Chinese Han population.Methods A case-control study including 412 patients with ACS and 337 controls free from CAD(coronary artery disease)was conducted.The TSP-4 A387P polymorphism was determined by PCR(polymerase chain reaction)and RFLP(restriction fragment length polymorphism)analysis.Results Slightly decreased frequency of GC genotype was observed in patients with ACS,compared with controls(5.3%vs 7.1%),but the difference did not reach statistical significance(P=0.31).Similarly,the prevalences of the C allele were 2/7%and 3.6%for ACS and control groups,respectively(P=0.32).None of the homozygotes was detected for the C allele.Further analyses in subjects subgrouped according to sex and age also showed no association of TSP-4 A387P polymorphism with ACS.Furthermore,after adjustment for conventional risk factors by multiple logistic regression analysis,the carrier prevalence of the C allele did not differ significantly between the ACS and control groups(OR=0.85;95%CI:0.45-1.59;P=0.60).ConclU8lon The present study suggested that the TSP-4 A387P variant show a low prevalence compared with western populations and fail to associate with an altered risk of ACS in the Chinese Han population.The findings further supplement experimental data for TSP-4 gene study of the coronary disease.展开更多
目的/意义 针对医疗器械制造商与用户设施不良事件报告(manufacturer and user facility device experience, MAUDE)数据库分析中存在的技术复杂度高与效率低等问题,设计并实现自动化分析框架,降低数据库分析难度并加速研究产出。方法/...目的/意义 针对医疗器械制造商与用户设施不良事件报告(manufacturer and user facility device experience, MAUDE)数据库分析中存在的技术复杂度高与效率低等问题,设计并实现自动化分析框架,降低数据库分析难度并加速研究产出。方法/过程 基于双链式结构设计AutoQUEST框架,其具备研究问题自动生成、结构化SQL查询构建及数据分析能力。通过5组案例评估框架查询成功率、执行时间及报告质量。结果/结论 在最优案例中,该框架查询成功率达100%,执行时间158秒,综合质量评分4.74分(满分5分),既能实现MAUDE数据库高效自动化分析,又能保持高质量的分析结果,可为医疗机构、医疗器械制造商及监管机构提供便捷可靠的数据分析支持。展开更多
文摘In this paper, we conduct research on the interactive training pattern and the applications on the modern emergency rescue training activities. In emergency rescue training linkage the ecological communities, important is not gathered themselves together, and not the size of the momentum and the strength that is not the amount of emergency rescue training linkage performance, important is the ecological communities each organic elements in the function of the cohesion, lies in the relationship between the organic elements in ecological communities, the construction and the development is the specific ecological communities in action elements of emergency rescue training, joint quality lies in the emergency rescue training. These contents are involved in the emergency rescue training linkage management model of concrete. Under this basis, we integrate the condition of the Hainan Medical School to propose the corresponding suggestions that will enhance the performance.
文摘Objective The thrombospondin-4(TSP-4)gene G29926C(A387P)polymorphism was recently reported to be associated with an increased risk for MI(myocardial infarction)in the American population.However,several subsequent studies produced controversial findings.The aim of this study was to explore the possible association of the TSP-4 A387P polymorphism with ACS(acute coronary syndrome)in a Chinese Han population.Methods A case-control study including 412 patients with ACS and 337 controls free from CAD(coronary artery disease)was conducted.The TSP-4 A387P polymorphism was determined by PCR(polymerase chain reaction)and RFLP(restriction fragment length polymorphism)analysis.Results Slightly decreased frequency of GC genotype was observed in patients with ACS,compared with controls(5.3%vs 7.1%),but the difference did not reach statistical significance(P=0.31).Similarly,the prevalences of the C allele were 2/7%and 3.6%for ACS and control groups,respectively(P=0.32).None of the homozygotes was detected for the C allele.Further analyses in subjects subgrouped according to sex and age also showed no association of TSP-4 A387P polymorphism with ACS.Furthermore,after adjustment for conventional risk factors by multiple logistic regression analysis,the carrier prevalence of the C allele did not differ significantly between the ACS and control groups(OR=0.85;95%CI:0.45-1.59;P=0.60).ConclU8lon The present study suggested that the TSP-4 A387P variant show a low prevalence compared with western populations and fail to associate with an altered risk of ACS in the Chinese Han population.The findings further supplement experimental data for TSP-4 gene study of the coronary disease.
文摘目的/意义 针对医疗器械制造商与用户设施不良事件报告(manufacturer and user facility device experience, MAUDE)数据库分析中存在的技术复杂度高与效率低等问题,设计并实现自动化分析框架,降低数据库分析难度并加速研究产出。方法/过程 基于双链式结构设计AutoQUEST框架,其具备研究问题自动生成、结构化SQL查询构建及数据分析能力。通过5组案例评估框架查询成功率、执行时间及报告质量。结果/结论 在最优案例中,该框架查询成功率达100%,执行时间158秒,综合质量评分4.74分(满分5分),既能实现MAUDE数据库高效自动化分析,又能保持高质量的分析结果,可为医疗机构、医疗器械制造商及监管机构提供便捷可靠的数据分析支持。