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黄连解毒汤对血热型银屑病动物模型免疫细胞及炎性因子表达的影响 被引量:4
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作者 罗光云 叶建州 +4 位作者 何丹 杨建婷 丛琳 孔祥一 杨雪松 《云南中医学院学报》 2022年第4期60-64,共5页
目的 研究黄连解毒汤对血热型银屑病小鼠模型免疫细胞及炎性因子表达的影响。方法 选取40只SKH-1雌性小鼠,随机分为正常组、模型组、消银颗粒组、黄连解毒汤组,各10只。除正常组外,其余各组均建立血热型银屑病模型,并于建模成功后分别... 目的 研究黄连解毒汤对血热型银屑病小鼠模型免疫细胞及炎性因子表达的影响。方法 选取40只SKH-1雌性小鼠,随机分为正常组、模型组、消银颗粒组、黄连解毒汤组,各10只。除正常组外,其余各组均建立血热型银屑病模型,并于建模成功后分别给予生理盐水、消银颗粒、黄连解毒汤处理。于建模后1 d、给药前1 d、给药后1周评价各组小鼠银屑病面积和严重程度指数(psoriasis area and severity index,PASI)差异,并分别于给药前1 d、给药后1周检测各组小鼠血清粒细胞集落刺激因子(granulocyte colony-stimulating factor,G-CSF)、白细胞介素-10(interleukin-10,IL-10)、IL-17水平变化,比较其血清CD4、CD8、CD11c表达变化。结果 模型组、黄连解毒汤组均建模成功,消银颗粒组建模成功9只。模型组、消银颗粒组、黄连解毒汤组给药前1 d、给药后1周PASI均较建模后1 d升高,且均高于正常组,消银颗粒组、黄连解毒汤组给药后1周PASI较给药前1 d下降。模型组、消银颗粒组、黄连解毒汤组给药前1 d、给药后1周IL-17均低于正常组,其G-CSF、IL-10均高于正常组;消银颗粒组、黄连解毒汤组给药后1周IL-17较给药前1 d升高,G-CSF、IL-10较给药前1 d下降。模型组、消银颗粒组、黄连解毒汤组给药前1 d、给药后1周CD4均低于正常组,其CD8、CD11c均高于正常组;消银颗粒组、黄连解毒汤组给药后1周CD4较给药前1 d升高,CD8、CD11c较给药前1 d下降。各组小鼠观察期间均未见毒副反应发生。结论 黄连解毒汤能够有效调节血热型银屑病小鼠免疫细胞及炎性因子表达,促进小鼠皮损的消退。 展开更多
关键词 黄连解毒汤 银屑病 免疫细胞 炎性因子
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氮素对茶树生理及品质成分影响的研究进展 被引量:7
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作者 刘健伟 方寒寒 +5 位作者 袁新跃 骆东亮 于璇 杨青 何丹 夏再瑾 《茶叶学报》 2018年第3期155-161,共7页
氮素是茶树生长所必需的大量元素,决定茶叶的产量与品质。氮素的吸收、同化、转移、不同氮素水平的供应,以及不同形态氮素的供应都显著调节着茶树的生理代谢以及品质成分,此外氮素与其它多种营养元素的交互作用,也深刻影响茶树的生长发... 氮素是茶树生长所必需的大量元素,决定茶叶的产量与品质。氮素的吸收、同化、转移、不同氮素水平的供应,以及不同形态氮素的供应都显著调节着茶树的生理代谢以及品质成分,此外氮素与其它多种营养元素的交互作用,也深刻影响茶树的生长发育,因此研究氮素对于茶树的影响具有现实的意义,本文结合我国近年来研究成果,系统综述了氮素对于茶树生理以及品质成分影响的研究进展,以期为氮素对茶树的系统研究提供理论基础,为茶树的高产优质提供科学依据。 展开更多
关键词 氮素水平 氮素形态 营养交互 茶树生理 品质代谢 基因
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Simulation and experiment of rice cleaning in air-separation device based on DEM-CFD coupling method 被引量:1
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作者 Xuedong Ma Lei Zhao +1 位作者 Bingjiang Guo he dang 《International Journal of Agricultural and Biological Engineering》 SCIE EI CAS 2020年第5期226-233,共8页
In order to study the movement characteristics and separation mechanism of rice and its impurities under the action of airflow,and lower the impurity rate in the cleaning operation process,rice and its impurities were... In order to study the movement characteristics and separation mechanism of rice and its impurities under the action of airflow,and lower the impurity rate in the cleaning operation process,rice and its impurities were modeled based on the“overlapping multi-sphere clump method”,the DEM-CFD coupling method was used to simulate rice cleaning process under different airflow velocity and airflow inclined angle,and combined with aerodynamics,the motion state and separation behavior of rice and its impurities in the flow field.The results showed that under horizontal airflow conditions,the average impurity rate of rice was the lowest when the airflow velocity was 9 m/s.When the flow velocity remains unchanged and the airflow inclined angle was set at 10°,the average impurity rate decreased,while the entrainment loss rate increased.The airflow velocity was negatively correlated with the impurity rate and positively correlated with the entrainment loss rate,while the airflow inclined angle was negatively correlated with the impurity rate and positively correlated with the entrainment loss rate.By designing and setting up an experimental device,an experiment was carried out with airflow velocity and airflow inclined angle as the factors,and the experimental results were consistent with the simulation results,indicating that it was reliable to study the physical behavior of rice-straw separation in the airflow field by using the DEM-CFD coupling method. 展开更多
关键词 DEM-CFD rice cleaning airflow velocity airflow inclined angle EXPERIMENT
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