Epigenetics is the discipline of regulating cellular activity through chemical modification or modulation of noncoding RNAs without altering the nucleotide sequence.Studies on this topic include the exploration of DNA...Epigenetics is the discipline of regulating cellular activity through chemical modification or modulation of noncoding RNAs without altering the nucleotide sequence.Studies on this topic include the exploration of DNA methylation,histone modification,noncoding RNA regulation,and chromatin remodeling.Derived from the apical tissues of young permanent teeth,stem cells from apical papilla are odontogenic adult stem cells with high proliferation,self-renewal capacity,and differentiation potential.These cells play crucial roles in root formation and development.This article focuses on the two epigenetic regulatory mechanisms of histone modifications and non-coding RNA.This review summarizes,generalizes,and evaluates the status of research on the epigenetic regulation of the multidirectional differentiation of stem cells from the apical papilla,aiming to explore the mechanisms underlying the multidirectional differentiation process of these stem cells.展开更多
文摘Epigenetics is the discipline of regulating cellular activity through chemical modification or modulation of noncoding RNAs without altering the nucleotide sequence.Studies on this topic include the exploration of DNA methylation,histone modification,noncoding RNA regulation,and chromatin remodeling.Derived from the apical tissues of young permanent teeth,stem cells from apical papilla are odontogenic adult stem cells with high proliferation,self-renewal capacity,and differentiation potential.These cells play crucial roles in root formation and development.This article focuses on the two epigenetic regulatory mechanisms of histone modifications and non-coding RNA.This review summarizes,generalizes,and evaluates the status of research on the epigenetic regulation of the multidirectional differentiation of stem cells from the apical papilla,aiming to explore the mechanisms underlying the multidirectional differentiation process of these stem cells.
文摘为提高小麦赤霉病预测预报精准度,在江苏宜兴市、句容市、姜堰区等6个地区试验田开展抽穗扬花期间田间孢子捕捉及鉴定,调查不同田块赤霉病病情指数(disease index,DI),测定收获的小麦籽粒中镰刀菌毒素污染水平,分析孢子组成对小麦赤霉病发生及其镰刀菌毒素污染程度的影响。结果表明,2020年6个地区试验田共捕捉镰刀菌孢子650株,其中禾谷镰刀菌复合种(Fusarium graminearum species complex,FGSC)占总孢子数的35.5%。淮南地区(宜兴市、句容市、姜堰区、盐都区)捕捉到的FGSC占当地捕捉总孢子数量的比例均在35%以上,但淮北地区(宿豫区、铜山区)均在27%以下,淮南地区试验田小麦赤霉病DI及镰刀菌毒素含量均显著高于淮北地区(P<0.05)。6个地区DI与镰刀菌毒素含量均与FGSC孢子数呈极显著正相关(P<0.01),但与当地总孢子数量没有相关性。采用子囊孢子飞散数量法预测赤霉病时,应对捕捉孢子中FGSC数量予以明确。
