Dear Editor,DNA methylation is a key epigenetic regulatory approach for many biological processes,such as genomic imprinting,epigenetic memory maintenance,aging,and neural development.In addition to 5-methylcytosine,D...Dear Editor,DNA methylation is a key epigenetic regulatory approach for many biological processes,such as genomic imprinting,epigenetic memory maintenance,aging,and neural development.In addition to 5-methylcytosine,DNA methylation at N6-deoxyadenosine(N6-mA)is the most prevalent DNA modification in prokaryotes[1].展开更多
基金The work was supported by grants from the National Institutes of Health(R01NS085176,R01GM111514,R01EY027347,R01EY030883,and R01EY031779)the Craig H.Neilsen Foundation(259450)the BrightFocus Foundation(G2017037).
文摘Dear Editor,DNA methylation is a key epigenetic regulatory approach for many biological processes,such as genomic imprinting,epigenetic memory maintenance,aging,and neural development.In addition to 5-methylcytosine,DNA methylation at N6-deoxyadenosine(N6-mA)is the most prevalent DNA modification in prokaryotes[1].