To the Editor:Obstructive sleep apnea(OSA)is one of the common sleep disorders in Parkinson’s disease(PD)that is often associated with sleep fragmentation and intermittent hypoxemia.[1]Clinically,it has been observed...To the Editor:Obstructive sleep apnea(OSA)is one of the common sleep disorders in Parkinson’s disease(PD)that is often associated with sleep fragmentation and intermittent hypoxemia.[1]Clinically,it has been observed that symptoms of OSA significantly overlap with both motor and non-motor symptoms of PD.However,the effect of OSA on the clinical symptoms of PD and the underlying mechanisms are still not well understood.OSA has been observed to induce sleep fragmentation and alterations in microscopic sleep architecture detected by electroencephalogram(EEG).展开更多
基金supported by grants from the National Key R&D Program of China(No.2017YFC 0909100)Jiangsu Provincial Medical Key Discipline(No.ZDXK202217)+5 种基金Suzhou Technology Development Programme(No.SLT201924 and SKJY2021090)Discipline Construction Program of the Second Affiliated Hospital of Soochow University(No.XKTJ XK202001)Science and Technology Innovation Project of Xiongan New Area(No.2023XAGG0073)Jiangsu Provincial Medical Key Discipline(No.ZDXK202217)Suzhou Key Laboratory(No.SZS2023015)the National Key R&D Program of China(No.2022YFC2503904).
文摘To the Editor:Obstructive sleep apnea(OSA)is one of the common sleep disorders in Parkinson’s disease(PD)that is often associated with sleep fragmentation and intermittent hypoxemia.[1]Clinically,it has been observed that symptoms of OSA significantly overlap with both motor and non-motor symptoms of PD.However,the effect of OSA on the clinical symptoms of PD and the underlying mechanisms are still not well understood.OSA has been observed to induce sleep fragmentation and alterations in microscopic sleep architecture detected by electroencephalogram(EEG).
